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1por Consolino, Lorena, Anemone, Annasofia, Capozza, Martina, Carella, Antonella, Irrera, Pietro, Corrado, Alessia, Dhakan, Chetan, Bracesco, Martina, Longo, Dario Livio“…This mini-review describes CEST-based methods to non-invasively investigate tumor metabolism and important metabolites involved, such as glucose and lactate, as well as measurement of tumor acidosis. …”
Publicado 2020
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2por Villano, Daisy, Romdhane, Feriel, Irrera, Pietro, Consolino, Lorena, Anemone, Annasofia, Zaiss, Moritz, Dastrù, Walter, Longo, Dario Livio“…To overcome these limitations, we propose a fast multislice CEST‐MRI sequence with high pH accuracy and spatial resolution. …”
Publicado 2020
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3por Anemone, Annasofia, Consolino, Lorena, Conti, Laura, Irrera, Pietro, Hsu, Myriam Y., Villano, Daisy, Dastrù, Walter, Porporato, Paolo E., Cavallo, Federica, Longo, Dario Livio“…MRI-CEST pH imaging successfully discriminated the more aggressive 4T1 and TS/A tumours that displayed a more acidic pH. …”
Publicado 2020
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4por Longo, Dario L., Sun, Phillip Zhe, Consolino, Lorena, Michelotti, Filippo C., Uggeri, Fulvio, Aime, Silvio“…[Image: see text] Chemical exchange saturation transfer (CEST) is a novel contrast mechanism for magnetic resonance imaging (MRI). …”
Publicado 2014
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5por Irrera, Pietro, Consolino, Lorena, Roberto, Miriam, Capozza, Martina, Dhakan, Chetan, Carella, Antonella, Corrado, Alessia, Villano, Daisy, Anemone, Annasofia, Navarro-Tableros, Victor, Bracesco, Martina, Dastrù, Walter, Aime, Silvio, Longo, Dario Livio“…In conclusion, this work shows that MRI-CEST tumor pH imaging is a valuable tool for assessing the in vivo treatment response to PPIs.…”
Publicado 2022
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6por Irrera, Pietro, Roberto, Miriam, Consolino, Lorena, Anemone, Annasofia, Villano, Daisy, Navarro-Tableros, Victor, Carella, Antonella, Dastrù, Walter, Aime, Silvio, Longo, Dario Livio“…Overall, this study highlights MRI-CEST tumor pH imaging as a valid approach to monitoring treatment response to PPIs.…”
Publicado 2022
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7por Avnet, Sofia, Lemma, Silvia, Cortini, Margherita, Di Pompo, Gemma, Perut, Francesca, Lipreri, Maria Veronica, Roncuzzi, Laura, Columbaro, Marta, Errani, Costantino, Longhi, Alessandra, Zini, Nicoletta, Heymann, Dominique, Dominici, Massimo, Grisendi, Giulia, Golinelli, Giulia, Consolino, Lorena, Longo, Dario Livio, Nanni, Cristina, Righi, Alberto, Baldini, Nicola“…In vivo subcutaneous and orthotopic models, co-injected with mesenchymal stromal (MSC) and osteosarcoma cells, formed an acidic tumour microenvironment (mean pH 6.86, as assessed by in vivo MRI-CEST pH imaging). In these xenografts, we enlightened the expression of both IL6 and the NF-kB complex subunit in stromal cells infiltrating the tumour acidic area. …”
Publicado 2021
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