Mostrando 1 - 20 Resultados de 35 Para Buscar '"The OA"', tiempo de consulta: 0.33s Limitar resultados
  1. 1
    “…OBJECTIVE: Epidemiological studies of knee osteoarthritis (OA) have often used a radiographic definition. However, the clinical syndrome of OA is influenced by a broad range of factors in addition to the structural changes required for radiographic OA. …”
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    How well do radiographic, clinical and self-reported diagnoses of knee osteoarthritis agree? Findings from the Hertfordshire cohort study
  2. 2
    “…Thirty-one percent (n = 238) knees demonstrated tibiofemoral OA, 28% (n = 220) showed patellofemoral OA, and 16% demonstrated OA in both locations. …”
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    Concordance between clinical and radiographic evaluations of knee osteoarthritis
  3. 3
    “…BACKGROUND: We consider the relationships between a clinical and radiological diagnosis of knee or hip OA and activities of daily-living (ADL) in older adults. …”
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    Impact of osteoarthritis on activities of daily living: does joint site matter?
  4. 4
    “…A variant in the FTO gene has been implicated in genetic risk to osteoarthritis (OA). We examined the role of the FTO polymorphism rs8044769 in risk of knee and hip OA in cases and controls incorporating body mass index (BMI) information. …”
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    The effect of FTO variation on increased osteoarthritis risk is mediated through body mass index: a mendelian randomisation study
  5. 5
    “…We therefore aimed to investigate whether sarcopenia is associated with a higher risk of radiographic (ROA) and symptomatic knee OA (SxOA) in a large cohort of North American people in the context of the OA initiative. …”
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    Lower Limb Muscle Strength and Muscle Mass Are Associated With Incident Symptomatic Knee Osteoarthritis: A Longitudinal Cohort Study
  6. 6
    “…INTRODUCTION: The authors examined how body mass index (BMI) across life is linked to the risk of midlife knee osteoarthritis (OA), testing whether prolonged exposure to high BMI or high BMI at a particular period has the greatest influence on the risk of knee OA. …”
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    Life course body mass index and risk of knee osteoarthritis at the age of 53 years: evidence from the 1946 British birth cohort study
  7. 7
    “…OBJECTIVE: To assess if a coding variant in the gene encoding transient receptor potential cation channel, subfamily V, member 1 (TRPV1) is associated with genetic risk of painful knee osteoarthritis (OA). METHODS: The Ile585Val TRPV1 variant encoded by rs8065080 was genotyped in 3270 cases of symptomatic knee OA, 1098 cases of asymptomatic knee OA and 3852 controls from seven cohorts from the UK, the USA and Australia. …”
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    The Ile585Val TRPV1 variant is involved in risk of painful knee osteoarthritis
  8. 8
    “…BACKGROUND: Some controversy exists regarding the safety of intra-articular hyaluronic acid (IAHA) in the management of osteoarthritis (OA). OBJECTIVE: The objective of this study was to re-assess the safety profile of IAHA in patients with OA, through a comprehensive meta-analysis of randomized, placebo-controlled trials. …”
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    Safety of Intra-articular Hyaluronic Acid Injections in Osteoarthritis: Outcomes of a Systematic Review and Meta-Analysis
  9. 9
    “…CONCLUSIONS: GS and CS can be considered safe treatments for patients with OA. All eligible studies on ASU included in our analysis used the proprietary product Piascledine(®) and allowed other anti-OA medications; thus, the safety of ASU must be confirmed in future studies without concomitant anti-OA medications. …”
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    Safety of Symptomatic Slow-Acting Drugs for Osteoarthritis: Outcomes of a Systematic Review and Meta-Analysis
  10. 10
    “…PURPOSE: To assess whether rheumatoid arthritis (RA) is associated with a greater risk of adverse events following total knee replacement (TKR) and total hip replacement (THR) than osteoarthritis (OA). PATIENTS AND METHODS: Individuals with a diagnosis of RA or OA were identified using primary care records. …”
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    The impact of rheumatoid arthritis on the risk of adverse events following joint replacement: a real-world cohort study
  11. 11
    “…Recent meta-analyses have shown a range of effects of OA on mortality, reflecting different OA definitions and study methods. …”
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    Knee osteoarthritis and time-to all-cause mortality in six community-based cohorts: an international meta-analysis of individual participant-level data
  12. 12
    “…Knee osteoarthritis (OA) is one of the most common and disabling medical conditions. …”
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    Multimodal Multidisciplinary Management of Patients with Moderate to Severe Pain in Knee Osteoarthritis: A Need to Meet Patient Expectations
  13. 13
    “…Osteoarthritis (OA), a disease affecting different patient phenotypes, appears as an optimal candidate for personalized healthcare. …”
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    Can We Identify Patients with High Risk of Osteoarthritis Progression Who Will Respond to Treatment? A Focus on Biomarkers and Frailty
  14. 14
    “…METHODS: Using the outcomes of several systematic reviews on the safety of anti-OA drugs, we summarized the ways in which harms have been reported in OA RCT manuscripts to date. …”
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    Recommendations for the Reporting of Harms in Manuscripts on Clinical Trials Assessing Osteoarthritis Drugs: A Consensus Statement from the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO)
  15. 15
    “…RESULTS: Study cohorts included 2070 OA and 142 RA patients for TKR and 2030 OA and 98 RA patients for THR. …”
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    The effect of rheumatoid arthritis on patient-reported outcomes following knee and hip replacement: evidence from routinely collected data
  16. 16
    “…BACKGROUND: Knee osteoarthritis (OA) is a common condition, associated with a high rate of disability and poor quality of life. …”
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    Knee osteoarthritis and adverse health outcomes: an umbrella review of meta-analyses of observational studies
  17. 17
    “…Osteoarthritis (OA) is the most common form of arthritis and a major cause of disability. …”
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    Large Scale Replication Study of the Association between HLA Class II/BTNL2 Variants and Osteoarthritis of the Knee in European-Descent Populations
  18. 18
    “…OBJECTIVE: Knee osteoarthritis (OA) has a significant genetic component. The authors have assessed the role of three variants reported to influence risk of knee OA with p<5×10–8 in determining patellofemoral and tibiofemoral Kellgren Lawrence (K/L) grade in knee OA cases. …”
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    Genetic contribution to radiographic severity in osteoarthritis of the knee
  19. 19
    “…Knee osteoarthritis (OA) is a heterogeneous disease, and identification of its subgroups/phenotypes can improve patient treatment and drug development. …”
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    Pain trajectory defines knee osteoarthritis subgroups: a prospective observational study
  20. 20
    “…OBJECTIVE: With adults working to older ages, occupation is an important, yet less modifiable domain of physical activity to consider in the risk of knee osteoarthritis (OA). This study aimed to investigate the association between predominant lifetime occupation and prevalent knee OA. …”
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    Predominant lifetime occupation and associations with painful and structural knee osteoarthritis: An international participant-level cohort collaboration
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