“…Similar trends were seen using the other case definition, except the decline in CA CRE rate since 2016 was not significant (Figure 3). [Figure: see text] [Figure: see text] [Figure: see text] CONCLUSION: Adjusted CRE incidence rates declined from 2016 to 2020 using current and prior case definitions but changes over time varied by epidemiologic class. …”
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“…Cases with recent COVID-19 had higher 30-day mortality than those without across all epi classes (Figure 2; p≤ .01 for all), with mortality highest among HO cases with recent COVID-19 (77%). …”
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“…Disease site specific symptoms were more common than constitutional symptoms in both groups. 36% of patients with pulmonary NTM were treated compared with 70% of patients with extra-pulmonary NTM (Table 3). 69% were referred to Pulmonologists, and 43% to infectious diseases for evaluation and management. [Figure: see text] Demographic data for patients with pulmonary and extrapulmonary NTM [Figure: see text] Mycobacterium species isolated from patients with pulmonary and extrapulmonary NTM [Figure: see text] Clinical characteristics of patients with pulmonary and extrapulmonary NTM including symptoms, referral to specialists, whether patients were diagnosed with disease by a clinician, and how many were treated. …”
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“…We used multivariable logistic regression to identify factors associated with COVID-19-associated hospitalization in persons with iSA infection and compared infection types and outcomes in iSA patients with and without prior COVID-19-associated hospitalization. [Figure: see text] RESULTS: Of 2,406 HA iSA cases reported, 146 (6.1%) had prior COVID-19-associated hospitalization. …”
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“…Percent tested varied by NHSN location type (Figure). Regression models identified location-type (oncology, critical care), laxatives use, chemotherapy, and residing in EIP catchment area predictive of testing (Figure). …”
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“…In multivariable analysis, age ≥ 65 years, recent hospitalization, chronic hemodialysis, and recent nitrofurantoin use were significantly associated with mrCDI (Table 2). [Figure: see text] [Figure: see text] CONCLUSION: Patients with iCDI who are older, on hemodialysis, or had recent hospitalization or nitrofurantoin use may be at increased risk of mrCDI and may benefit from early use of adjunctive therapy to prevent mrCDI. …”
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“…FFQ decreased significantly in 11 of 15 regions (P < 0.05, Figures 1 and 2). The median (IQR) FFQ RR for the regions was 0.83 (0.81, 0.87) (Figure 3). …”
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“…Figure. Frequency of Cases Discharged in the 12 Weeks Prior to Readmission with Clostridioides difficile Infection (N=1138*) [Image: see text] CONCLUSION: A third of hospitalized CO CDI had been recently discharged from the same hospital, and most had received antibiotics during or soon after the last admission. …”
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“…RESULTS: Of 1,018 candidemia cases in 2017, 123 (12%) occurred in the context of recent IDU (1% in Minnesota and 27% in New Mexico) (Figure 1). In the 4 states with pre-2017 data, the proportion of IDU cases increased from 7% in 2014 to 15% in 2017, with the proportion in Tennessee nearly tripling from 7% to 18% (Figure 2). …”
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“…[Figure: see text] +Adjusted for gender, race/ethnicity, and education. …”
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“…Similarly, the 30-day mortality rates decreased, with the largest decrease among persons aged ≥85 years: from 310 cases to 169 cases per 100,000 population (Figure 1). The percentage of isolates due to NAP1/027 decreased from 20.3% in 2011 to 6.5% in 2016. …”
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“…The percentage of patients on fluoroquinolones was lower in 2015, while percentages of patients on carbapenems or cephalosporins were higher in 2015 than in 2011 (figure). [Image: see text] CONCLUSION: Some observed differences between 2011 and 2015 provide evidence of stewardship impact. …”
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“…The pathway categorized FQ treatment as supported for 646 (85.4%) and unsupported for 110 patients (14.6%) (figure). Almost half of unsupported treatment was due to a lack of compatible signs or symptoms of infection in a patient from whom an organism susceptible or likely susceptible to an FQ was identified from a nonsterile site (49/110 patients, 44.5%), suggesting colonization. …”
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“…Interestingly, CA cases were more widely spread across SVI quartiles compared to HA cases; a higher proportion of HA cases resided in census tracts in the 3rd or 4th SVI quartiles (Table 1). [Figure: see text] CONCLUSION: Patient-specific risk factors classically associated with HA ESBL are less commonly associated with CA ESBL in Monroe County. …”
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“…Among the three sites with four full years of data, a different trend was seen in each (Figure). Trends in GA and MN were statistically significant, and no significant trend was seen in OR. …”
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“…RESULTS: In 161 NHs (mean certified beds 118, 92% dual certified, 68% for-profit), the % of NHs reporting implementation of the 15 activities (figure) ranged from 25% (has a formulary of antibiotic agents, providers required to perform an antibiotic “time-out”) to 88% (providers required to document dose, duration and indication). …”
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“…Among the 1,268 antibacterials (figure), fluoroquinolones (15%), combination penicillins (8%), third-generation cephalosporins (8%), and glycopepetides (5%) ranked among the top 10 classes in use. …”
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“…Risk factors for recurrence were: injection drug use (IDU) (aOR; 1.38, 95% confidence interval [CI]: 1.15–1.65), central venous catheters (aOR; 1.35, 95% CI: 1.22–1.51), dialysis (aOR; 2.00, 95% CI: 1.74–2.31), and history of MRSA colonization (aOR; 1.35, 95% CI: 1.22–1.51) (figure). Recurrence was more likely for bloodstream infections (BSI) without another infection (aOR; 2.08, 95% CI: 1.74–2.48), endocarditis (aOR; 1.46, 95% CI: 1.16–1.55), and bone/joint infections (aOR; 1.38, 95% CI: 1.20–1.59), and less likely for pneumonia (aOR: 0.75, 95% CI: 0.64–0.89), compared with other initial infection types. …”
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“…The median number of weeks from prior hospitalization to CDI was 27 (IQR 18–38, Figure 1). Cases had a higher risk of hospitalization than matched controls in the prior 3–6 months (amOR: 2.33, 95% CI: 1.87, 2.90) and 6–12 months (amOR: 1.43 95% CI: 1.18, 1.74). …”
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“…RESULTS: HACO MRSA incidence declined overall from 2009 to 2016 but increased from 2016 to 2017 overall (8%), for both PWID (63%) and others (5%) (figure). For both PWID and non-PWID, incidence from 2016 to 2017 increased by 0.5 cases/100,000 population; 91% of the increase in PWID occurred in cases with a past year hospitalization while 78% of the increase in cases not associated with injection drug use (IDU) occurred in cases with past year LTCF residence. …”
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