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1por Nakatsuji, Teruaki, Liu, Yu-Tsueng, Huang, Cheng-Po, Gallo, Richard L., Huang, Chun-Ming“…BACKGROUND: Acne vulgaris afflicts more than fifty million people in the United State and the severity of this disorder is associated with the immune response to Propionibacterium acnes (P. acnes). …”
Publicado 2008
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4por Nakatsuji, Teruaki, Tang, De-chu C., Zhang, Liangfang, Gallo, Richard L., Huang, Chun-Ming“…BACKGROUND: In the progression of acne vulgaris, the disruption of follicular epithelia by an over-growth of Propionibacterium acnes (P. acnes) permits the bacteria to spread and become in contact with various skin and immune cells. …”
Publicado 2011
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5“…Acne is one of the most common skin diseases worldwide and results in major health care costs and significant morbidity to severely affected individuals. …”
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6por Almoughrabie, Samia, Cau, Laura, Cavagnero, Kellen, O’Neill, Alan M., Li, Fengwu, Roso-Mares, Andrea, Mainzer, Carine, Closs, Brigitte, Kolar, Matthew J., Williams, Kevin J., Bensinger, Steven J., Gallo, Richard L.“…A similar response occurred in mouse epidermis and in human skin affected with acne. Further analysis showed that this increase in lipids was mediated by short-chain fatty acids produced by Cutibacterium acnes and was dependent on increased expression of several lipid synthesis genes including glycerol-3-phosphate-acyltransferase-3. …”
Publicado 2023
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7por Nakamura, Kouki, O’Neill, Alan M., Williams, Michael R., Cau, Laura, Nakatsuji, Teruaki, Horswill, Alexander R., Gallo, Richard L.“…Since S. epidermidis coexists with abundant Cutibacteria acnes on healthy human skin and does not typically form a biofilm in this environment, we hypothesized that C. acnes may influence biofilm formation of S. epidermidis. …”
Publicado 2020
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8por Dréno, Brigitte, Gallo, Richard L., Berardesca, Enzo, Griffiths, Christopher E. M.Enlace del recurso
Publicado 2022
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9por Wang, Yanhan, Kao, Ming-Shan, Yu, Jinghua, Huang, Stephen, Marito, Shinta, Gallo, Richard L., Huang, Chun-Ming“…Acne dysbiosis happens when there is a microbial imbalance of the over-growth of Propionibacterium acnes (P. acnes) in the acne microbiome. …”
Publicado 2016
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10por Shu, Muya, Wang, Yanhan, Yu, Jinghua, Kuo, Sherwin, Coda, Alvin, Jiang, Yong, Gallo, Richard L., Huang, Chun-Ming“…Here, we demonstrate that fermentation of glycerol with Propionibacterium acnes (P. acnes), a skin commensal bacterium, can function as a skin probiotic for in vitro and in vivo growth suppression of USA300, the most prevalent community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA). …”
Publicado 2013
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11“…These observations indicate that the normal human skin microflora protects skin via various modes of action, a conclusion supported by many lines of evidence associating diseases such as acne, atopic dermatitis, psoriasis and rosacea with an imbalance of the microflora even in the absence of classical infection. …”
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12“…Imbalances in the skin microbiome, known as dysbiosis, have been linked to various inflammatory skin disorders, including atopic dermatitis, acne, and psoriasis. The roles of abundant commensal bacteria belonging to Staphylococcus and Cutibacterium taxa and the fungi Malassezia, where particular species or strains can benefit the host or cause disease, are increasingly appreciated in skin disorders. …”
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13por Wang, Yanhan, Zhu, Wenhong, Shu, Muya, Jiang, Yong, Gallo, Richard L., Liu, Yu-Tsueng, Huang, Chun-Ming“…To test our hypothesis, P. acnes was exposed to UV-B radiation. The production of porphyrins in P. acnes was significantly reduced with increasing doses of UV-B. …”
Publicado 2012
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