-
1por Rodgers, Mary A., Shah, Pir A., Anderson, Mark, Vallari, Ana S., Gersch, Jeffrey, Mbanya, Dora, Sauleda Oliveras, Silvia, Choudhry, Saad, Leary, Thomas P., Kuhns, Mary C., Dawson, George J., Cloherty, Gavin A., Lau, Daryl T.Y.“…To evaluate the clinical utility of HBsAg isoforms, we developed novel prototype assays on the ARCHITECT automated serology platform that specifically detects total-HBsAg (T-HBsAg), large (L-HBsAg), and middle (M-HBsAg) products of the S gene to determine the isoform composition of human specimens from acute and chronic HBV infection and during long-term nucleos(t)ide analog therapy. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
2Development and performance of prototype serologic and molecular tests for hepatitis delta infectionpor Coller, Kelly E., Butler, Emily K., Luk, Ka-Cheung, Rodgers, Mary A., Cassidy, Michael, Gersch, Jeffrey, McNamara, Anne L., Kuhns, Mary C., Dawson, George J., Kaptue, Lazare, Bremer, Birgit, Wedemeyer, Heiner, Cloherty, Gavin A.“…Prototype molecular (RNA) and serologic (IgG) assays were developed for high-throughput testing on the Abbott m2000 and ARCHITECT systems, respectively. RNA detection was achieved through amplification of a ribozyme region target, with a limit of detection of 5 IU/ml. …”
Publicado 2018
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto