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1“…We regularly import and process more than 15 different NHS open datasets to deliver OpenPrescribing.net, one of the most high-impact use cases for NHS England’s open data, with over 15,000 unique users each month. …”
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2por Curtis, Helen J., Dennis, John M., Shields, Beverley M., Walker, Alex J., Bacon, Seb, Hattersley, Andrew T., Jones, Angus G., Goldacre, Ben“…MATERIALS AND METHODS: We evaluated time trends for the period 1998 to 2016, using England's publicly available prescribing datasets, and stratified these by the order in which they were prescribed to patients using the Clinical Practice Research Datalink. …”
Publicado 2018
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3“…METHODS: Tamoxifen and raloxifene data were extracted from England’s monthly prescribing data sets, October 2010–October 2017. …”
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4por Yang, Ya-Ting, Zhong, Xiaomin, Fahmi, Ali, Watts, Simon, Ashcroft, Darren M., Massey, Jon, Fisher, Louis, MacKenna, Brian, Mehrkar, Amir, Bacon, Sebastian C. J., Goldacre, Ben, Hand, Kieran, van Staa, Tjeerd, Palin, Victoria“…METHODS: With the approval of NHS England, a retrospective cohort study using the OpenSAFELY platform analysed routinely collected electronic health data from GP practices in England between January 2019 and December 2021. …”
Publicado 2023
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6por Andrews, Colm, Schultze, Anna, Curtis, Helen, Hulme, William, Tazare, John, Evans, Stephen, Mehrkar, Amir, Bacon, Sebastian, Hickman, George, Bates, Christopher, Parry, John, Hester, Frank, Harper, Sam, Cockburn, Jonathan, Evans, David, Ward, Tom, Davy, Simon, Inglesby, Peter, Goldacre, Ben, MacKenna, Brian, Tomlinson, Laurie, Walker, Alex“…OpenSAFELY-TPP data is derived from practices in England using SystmOne software, and has been used for the majority of these studies. …”
Publicado 2022
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7por Zhong, Xiaomin, Pate, Alexander, Yang, Ya-Ting, Fahmi, Ali, Ashcroft, Darren M., Goldacre, Ben, MacKenna, Brian, Mehrkar, Amir, Bacon, Sebastian C.J., Massey, Jon, Fisher, Louis, Inglesby, Peter, Hand, Kieran, van Staa, Tjeerd, Palin, Victoria“…METHODS: With the approval of NHS England, we used OpenSAFELY platform to access the TPP SystmOne electronic health record (EHR) system and selected patients prescribed antibiotics from 2019 to 2021. …”
Publicado 2023
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8por Feldman, Harriet Ruth, DeVito, Nicholas J, Mendel, Jonathan, Carroll, David E, Goldacre, Ben“…SETTING: NHS Trusts (secondary/tertiary care organisations) in England. PARTICIPANTS: 236 Trusts were contacted, of which 217 responded. …”
Publicado 2018
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9por Rowan, Anna, Bates, Chris, Hulme, William, Evans, David, Davy, Simon, A Kennedy, Nicholas, Galloway, James, E Mansfield, Kathryn, Bechman, Katie, Matthewman, Julian, Yates, Mark, Brown, Jeremy, Schultze, Anna, Norton, Sam, J. Walker, Alex, E. Morton, Caroline, Bhaskaran, Krishnan, T. Rentsch, Christopher, Williamson, Elizabeth, Croker, Richard, Bacon, Seb, Hickman, George, Ward, Tom, Green, Amelia, Fisher, Louis, J Curtis, Helen, Tazare, John, M. Eggo, Rosalind, Inglesby, Peter, Cockburn, Jonathan, I. McDonald, Helen, Mathur, Rohini, YS Wong, Angel, Forbes, Harriet, Parry, John, Hester, Frank, Harper, Sam, J Douglas, Ian, Smeeth, Liam, A Tomlinson, Laurie, W Lees, Charlie, Evans, Stephen, Smith, Catherine, M. Langan, Sinéad, Mehkar, Amir, MacKenna, Brian, Goldacre, Ben“…With the approval of NHS England, we set out to obtain data on one specific group of medicines, “high-cost drugs” (HCD) which are typically specialist medicines for the management of long-term conditions, prescribed by hospitals to patients. …”
Publicado 2021
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11por Forbes, Harriet, Morton, Caroline E, Bacon, Seb, McDonald, Helen I, Minassian, Caroline, Brown, Jeremy P, Rentsch, Christopher T, Mathur, Rohini, Schultze, Anna, DeVito, Nicholas J, MacKenna, Brian, Hulme, William J, Croker, Richard, Walker, Alex J, Williamson, Elizabeth J, Bates, Chris, Mehrkar, Amir, Curtis, Helen J, Evans, David, Wing, Kevin, Inglesby, Peter, Drysdale, Henry, Wong, Angel Y S, Cockburn, Jonathan, McManus, Robert, Parry, John, Hester, Frank, Harper, Sam, Douglas, Ian J, Smeeth, Liam, Evans, Stephen J W, Bhaskaran, Krishnan, Eggo, Rosalind M, Goldacre, Ben, Tomlinson, Laurie A“…DESIGN: Population based cohort study, on behalf of NHS England. SETTING: Primary care data and pseudonymously linked hospital and intensive care admissions and death records from England, during wave 1 (1 February to 31 August 2020) and wave 2 (1 September to 18 December 2020). …”
Publicado 2021
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12por Wood, Angela, Denholm, Rachel, Hollings, Sam, Cooper, Jennifer, Ip, Samantha, Walker, Venexia, Denaxas, Spiros, Akbari, Ashley, Banerjee, Amitava, Whiteley, William, Lai, Alvina, Sterne, Jonathan, Sudlow, Cathie, Douiri, Abdel, Akinoso-Imran, Abdul Qadr, Jonas, Adrian, Shah, Ajay, Handy, Alex, Davies, Alun, Kurdi, Amanj, Hansell, Anna, Docherty, Annemarie, Pherwani, Arun, Dashtban, Ashkan, Bray, Ben, Cairns, Ben, Goldacre, Ben, Humberstone, Ben, Mateen, Bilal, Doble, Brett, Roberts, Brian, Morris, Carole, Dale, Caroline, Rogers, Caroline, Wolfe, Charles, Tomlinson, Christopher, Lawson, Claire, du Toit, Clea, Berry, Colin, Smith, Craig, O’Connell, Dan, Harris, Daniel, Brind, David, Cromwell, David, Hughes, David, Martos, David Moreno, Ringham, Debbie, Lawler, Deborah, Lowe, Deborah, Nikiphorou, Elena, Withnell, Eloise, Di Angelantonio, Emanuele, Morris, Eva, Birney, Ewan, Falck, Fabian, Torabi, Fatemeh, Greaves, Felix, Falter, Florian, Zaccardi, Francesco, Kee, Frank, Davies, Gareth, Nicholson, George, Curry, Gwenetta, Zhang, Haoting, Hemingway, Harry, Wilde, Harry, Abbasizanjani, Hoda, Wu, Honghan, Tang, Howard, Wang, Huan, Mordi, Ify, MacArthur, Jackie, Lyons, Jane, Beveridge, Jennifer, Barrett, Jessica, Wu, Jianhua, Thygesen, Johan, Danesh, John, Dennis, John, Boyle, Jon, Halcox, Julian, Khunti, Kamlesh, Cheema, Kate, Brown, Katherine, Li, Ken, Kavanagh, Kim, North, Laura, Pasea, Laura, Ellins, Libby, Pierotti, Livia, Wright, Lucy, Martin, Lydia, Morrice, Lynn, Mamas, Mamas, Bennie, Marion, Barber, Mark, Macleod, Mary Joan, Caputo, Massimo, Buch, Maya, Mizani, Mehrdad, Katsoulis, Michalis, Gravenor, Mike, Inouye, Mike, Skrypak, Mirek, Gerstung, Moritz, Pirmohamed, Munir, Glickman, Myer, Herz, Naomi, Davies, Neil, Hall, Nick, Samani, Nilesh, Seminog, Olena, Lorgelly, Paula, Machado, Pedro, Li, Qiuju, Denholm, Rachel, Goldacre, Raph, Carragher, Raymond, Sofat, Reecha, Takhar, Rohan, Lyons, Ronan, Priedon, Rouven, Griffiths, Rowena, Payne, Rupert, Kolamunnage-Dona, Ruwanthi, Salim, Safa, Padmanabhan, Sandosh, Onida, Sarah, Kent, Seamus, Bacon, Seb, Manohar, Sinduja, Babu-Narayan, Sonya, Keene, Spencer, Varma, Susheel, Lawrence, Thomas, Wang, Tianxiao, Wilkinson, Tim, Norris, Tom, Palmer, Tom, Nafilyan, Vahé“…OBJECTIVE: To describe a novel England-wide electronic health record (EHR) resource enabling whole population research on covid-19 and cardiovascular disease while ensuring data security and privacy and maintaining public trust. …”
Publicado 2021
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13por Lemanska, Agnieszka, Andrews, Colm, Fisher, Louis, Butler-Cole, Ben, Mehrkar, Amir, Roberts, Keith J, Goldacre, Ben, Walker, Alex J, MacKenna, Brian“…DATA SOURCES: With the approval of NHS England, we conducted this study using 24 million electronic healthcare records of people within the OpenSAFELY-TPP research platform. …”
Publicado 2023
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14por Curtis, Helen J, MacKenna, Brian, Wiedemann, Milan, Fisher, Louis, Croker, Richard, Morton, Caroline E, Inglesby, Peter, Walker, Alex J, Morley, Jessica, Mehrkar, Amir, Bacon, Sebastian CJ, Hickman, George, Evans, David, Ward, Tom, Davy, Simon, Hulme, William J, Macdonald, Orla, Conibere, Robin, Lewis, Tom, Myers, Martin, Wanninayake, Shamila, Collison, Kiren, Drury, Charles, Samuel, Miriam, Sood, Harpreet, Cipriani, Andrea, Fazel, Seena, Sharma, Manuj, Baqir, Wasim, Bates, Chris, Parry, John, Goldacre, Ben“…DESIGN AND SETTING: With the approval of NHS England, a cohort study was conducted of 23.8 million patient records in general practice, in situ using OpenSAFELY. …”
Publicado 2023
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15por Tazare, John, Walker, Alex J., Tomlinson, Laurie A., Hickman, George, Rentsch, Christopher T., Williamson, Elizabeth J., Bhaskaran, Krishnan, Evans, David, Wing, Kevin, Mathur, Rohini, Wong, Angel YS., Schultze, Anna, Bacon, Seb, Bates, Chris, Morton, Caroline E., Curtis, Helen J., Nightingale, Emily, McDonald, Helen I., Mehrkar, Amir, Inglesby, Peter, Davy, Simon, MacKenna, Brian, Cockburn, Jonathan, Hulme, William J., Warren-Gash, Charlotte, Bhate, Ketaki, Nitsch, Dorothea, Powell, Emma, Mulick, Amy, Forbes, Harriet, Minassian, Caroline, Croker, Richard, Parry, John, Hester, Frank, Harper, Sam, Eggo, Rosalind M., Evans, Stephen JW., Smeeth, Liam, Douglas, Ian J, Goldacre, Ben“…Methods: Working on behalf of NHS England, we used linked primary care records, death certificate and hospital data from the OpenSAFELY platform. …”
Publicado 2022
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16por Lemanska, Agnieszka, Andrews, Colm, Fisher, Louis, Bacon, Seb, Frampton, Adam E, Mehrkar, Amir, Inglesby, Peter, Davy, Simon, Roberts, Keith, Patalay, Praveetha, Goldacre, Ben, MacKenna, Brian, Walker, Alex J“…METHODS: With the approval of NHS England, and drawing from a nationally representative OpenSAFELY-TPP dataset of 24 million patients (over 40% of the English population), we undertook a cohort study of people diagnosed with pancreatic cancer. …”
Publicado 2023
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17por Curtis, Helen J, MacKenna, Brian, Croker, Richard, Inglesby, Peter, Walker, Alex J, Morley, Jessica, Mehrkar, Amir, Morton, Caroline E, Bacon, Seb, Hickman, George, Bates, Chris, Evans, David, Ward, Tom, Cockburn, Jonathan, Davy, Simon, Bhaskaran, Krishnan, Schultze, Anna, Rentsch, Christopher T, Williamson, Elizabeth J, Hulme, William J, McDonald, Helen I, Tomlinson, Laurie, Mathur, Rohini, Drysdale, Henry, Eggo, Rosalind M, Wing, Kevin, Wong, Angel YS, Forbes, Harriet, Parry, John, Hester, Frank, Harper, Sam, Evans, Stephen JW, Douglas, Ian J, Smeeth, Liam, Goldacre, Ben“…DESIGN AND SETTING: Working on behalf of NHS England, a cohort study was conducted of 23.8 million patient records in general practice, in situ using OpenSAFELY. …”
Publicado 2021
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18por Walker, Jemma L, Schultze, Anna, Tazare, John, Tamborska, Arina, Singh, Bhagteshwar, Donegan, Katherine, Stowe, Julia, Morton, Caroline E, Hulme, William J, Curtis, Helen J, Williamson, Elizabeth J, Mehrkar, Amir, Eggo, Rosalind M, Rentsch, Christopher T, Mathur, Rohini, Bacon, Sebastian, Walker, Alex J, Davy, Simon, Evans, David, Inglesby, Peter, Hickman, George, MacKenna, Brian, Tomlinson, Laurie, CA Green, Amelia, Fisher, Louis, Cockburn, Jonathan, Parry, John, Hester, Frank, Harper, Sam, Bates, Christopher, Evans, Stephen JW, Solomon, Tom, Andrews, Nick J, Douglas, Ian J, Goldacre, Ben, Smeeth, Liam, McDonald, Helen I“…METHODS: With the approval of NHS England we analysed primary care data from >17 million patients in England linked to emergency care, hospital admission and mortality records in the OpenSAFELY platform. …”
Publicado 2022
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19por Green, Amelia, Curtis, Helen, Hulme, William, Williamson, Elizabeth, McDonald, Helen, Bhaskaran, Krishnan, Rentsch, Christopher, Schultze, Anna, MacKenna, Brian, Mahalingasivam, Viyaasan, Tomlinson, Laurie, Walker, Alex, Fisher, Louis, Massey, Jon, Andrews, Colm, Hopcroft, Lisa, Morton, Caroline, Croker, Richard, Morley, Jessica, Mehrkar, Amir, Bacon, Seb, Evans, David, Inglesby, Peter, Hickman, George, Ward, Tom, Davy, Simon, Mathur, Rohini, Tazare, John, Eggo, Rosalind, Wing, Kevin, Wong, Angel, Forbes, Harriet, Bates, Chris, Cockburn, Jonathan, Parry, John, Hester, Frank, Harper, Sam, Douglas, Ian, Evans, Stephen, Smeeth, Liam, Goldacre, Ben“…CONCLUSIONS: While the majority of COVID-19 vaccine breakthrough cases in England were mild, some differences in rates of breakthrough cases have been identified in several clinical groups. …”
Publicado 2022
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20por Grint, Daniel J, Wing, Kevin, Williamson, Elizabeth, McDonald, Helen I, Bhaskaran, Krishnan, Evans, David, Evans, Stephen JW, Walker, Alex J, Hickman, George, Nightingale, Emily, Schultze, Anna, Rentsch, Christopher T, Bates, Chris, Cockburn, Jonathan, Curtis, Helen J, Morton, Caroline E, Bacon, Sebastian, Davy, Simon, Wong, Angel YS, Mehrkar, Amir, Tomlinson, Laurie, Douglas, Ian J, Mathur, Rohini, Blomquist, Paula, MacKenna, Brian, Ingelsby, Peter, Croker, Richard, Parry, John, Hester, Frank, Harper, Sam, DeVito, Nicholas J, Hulme, Will, Tazare, John, Goldacre, Ben, Smeeth, Liam, Eggo, Rosalind M“…We found increased risk of death for VOC compared with non-VOC cases in England (hazard ratio: 1.67; 95% confidence interval: 1.34–2.09; p < 0.0001). …”
Publicado 2021
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