Mostrando 1 - 20 Resultados de 28 Para Buscar '"Drosophila melanogaster"', tiempo de consulta: 0.14s Limitar resultados
  1. 1
    “…We exposed four Drosophila melanogaster strains to malathion, a commonly used organophosphate insecticide. …”
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    Transposable elements contribute to the genomic response to insecticides in Drosophila melanogaster
  2. 2
    “…In this work, we conduct a genome-wide screen for adaptive TE insertions in Drosophila melanogaster that have taken place during or after the spread of this species out of Africa. …”
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    High Rate of Recent Transposable Element–Induced Adaptation in Drosophila melanogaster
  3. 3
    “…Drosophila melanogaster is an important model for antiviral immunity in arthropods, but very few DNA viruses have been described from the family Drosophilidae. …”
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    The discovery, distribution, and diversity of DNA viruses associated with Drosophila melanogaster in Europe
  4. 4
    “…We assessed the accuracy of this approach on whole, complex eukaryotic genomes by resequencing pools of largely isogenic, individually sequenced Drosophila melanogaster strains. We called SNPs in the pooled data and estimated false positive and false negative rates using the SNPs called in individual strain as a reference. …”
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    Empirical Validation of Pooled Whole Genome Population Re-Sequencing in Drosophila melanogaster
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    Exploring the Phenotypic Space and the Evolutionary History of a Natural Mutation in Drosophila melanogaster
  6. 6
    “…We have previously identified a putatively adaptive transposable element in the Drosophila melanogaster genome, named FBti0019170, inserted in a kuz intron. …”
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    Natural and laboratory mutations in kuzbanian are associated with zinc stress phenotypes in Drosophila melanogaster
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    Stress affects the epigenetic marks added by natural transposable element insertions in Drosophila melanogaster
  8. 8
    “…Signatures of spatially varying selection have been investigated both at the genomic and transcriptomic level in several organisms. In Drosophila melanogaster, the majority of these studies have analyzed North American and Australian populations, leading to the identification of several loci and traits under selection. …”
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    Genome-wide patterns of local adaptation in Western European Drosophila melanogaster natural populations
  9. 9
    “…While several studies in a diverse set of species have shed light on the genes underlying adaptation, our knowledge on the selective pressures that explain the observed patterns lags behind. Drosophila melanogaster is a valuable organism to study environmental adaptation because this species originated in Southern Africa and has recently expanded worldwide, and also because it has a functionally well‐annotated genome. …”
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    Temperature, rainfall and wind variables underlie environmental adaptation in natural populations of Drosophila melanogaster
  10. 10
    “…In this work, we take advantage of the wealth of information available for Drosophila melanogaster and humans to analyze the role of transposable elements in six stress regulatory networks: immune, hypoxia, oxidative, xenobiotic, heat shock, and heavy metal. …”
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    Diverse families of transposable elements affect the transcriptional regulation of stress-response genes in Drosophila melanogaster
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    A unique cluster of roo insertions in the promoter region of a stress response gene in Drosophila melanogaster
  12. 12
    por Kapun, Martin, Barrón, Maite G, Staubach, Fabian, Obbard, Darren J, Wiberg, R Axel W, Vieira, Jorge, Goubert, Clément, Rota-Stabelli, Omar, Kankare, Maaria, Bogaerts-Márquez, María, Haudry, Annabelle, Waidele, Lena, Kozeretska, Iryna, Pasyukova, Elena G, Loeschcke, Volker, Pascual, Marta, Vieira, Cristina P, Serga, Svitlana, Montchamp-Moreau, Catherine, Abbott, Jessica, Gibert, Patricia, Porcelli, Damiano, Posnien, Nico, Sánchez-Gracia, Alejandro, Grath, Sonja, Sucena, Élio, Bergland, Alan O, Guerreiro, Maria Pilar Garcia, Onder, Banu Sebnem, Argyridou, Eliza, Guio, Lain, Schou, Mads Fristrup, Deplancke, Bart, Vieira, Cristina, Ritchie, Michael G, Zwaan, Bas J, Tauber, Eran, Orengo, Dorcas J, Puerma, Eva, Aguadé, Montserrat, Schmidt, Paul, Parsch, John, Betancourt, Andrea J, Flatt, Thomas, González, Josefa
    Publicado 2020
    “…Here, we address these issues using a collaborative approach, sequencing 48 pooled population samples from 32 locations, and perform the first continent-wide genomic analysis of genetic variation in European Drosophila melanogaster. Our analyses uncover longitudinal population structure, provide evidence for continent-wide selective sweeps, identify candidate genes for local climate adaptation, and document clines in chromosomal inversion and transposable element frequencies. …”
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    Genomic Analysis of European Drosophila melanogaster Populations Reveals Longitudinal Structure, Continent-Wide Selection, and Previously Unknown DNA Viruses
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    “…The advent of long-read sequencing technologies has allowed the generation of multiple high-quality de novo genome assemblies for multiple species, including well-known model species such as Drosophila melanogaster. Genome assemblies for multiple individuals of the same species are key to discover the genetic diversity present in natural populations, especially the one generated by transposable elements, the most common type of structural variant. …”
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    DrosOmics: A Browser to Explore -omics Variation Across High-Quality Reference Genomes From Natural Populations of Drosophila melanogaster
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    “…We present a protocol for generating a precise deletion, without altering the genetic background of the strain, of a transposable element (TE) in a natural population of Drosophila melanogaster using two steps of CRISPR-Cas9 homology-directed repair. …”
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    Two-step CRISPR-Cas9 protocol for transposable element deletion in D. melanogaster natural populations
  15. 15
    por Guio, Lain, González, Josefa
    Publicado 2015
    “…In this work, we take advantage of a recently characterized transposable element insertion mediating oxidative stress response in Drosophila melanogaster to test the dominance effect of an adaptive mutation. …”
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    The Dominance Effect of the Adaptive Transposable Element Insertion Bari-Jheh Depends on the Genetic Background
  16. 16
    por Mateo, Lidia, González, Josefa
    Publicado 2014
    “…In this work, we take advantage of the high-quality genome sequence and the wealth of functional information available for Drosophila melanogaster to further investigate the possibility of additional independent domestications of pogo-like transposases into host CENP-B related proteins. …”
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    Pogo-like Transposases Have Been Repeatedly Domesticated into CENP-B-Related Proteins
  17. 17
    “…To advance our understanding of adaptation to temporally varying selection pressures, we identified signatures of seasonal adaptation occurring in parallel among Drosophila melanogaster populations. Specifically, we estimated allele frequencies genome-wide from flies sampled early and late in the growing season from 20 widely dispersed populations. …”
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    Broad geographic sampling reveals the shared basis and environmental correlates of seasonal adaptation in Drosophila
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    “…We experimentally validated the accuracy of T-lex detecting presence or absence of 768 previously identified TE copies in two resequenced Drosophila melanogaster strains. Approximately 95% of the TE insertions were detected with 100% sensitivity and 97% specificity. …”
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    T-lex: a program for fast and accurate assessment of transposable element presence using next-generation sequencing data
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    “…We validated our method by performing simulations and by using real data to accurately predict the alleles of well-known recombination modifiers, including common inversions in Drosophila melanogaster and human, and the chromosomes under selective pressure at the lactase locus in humans. …”
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    Identifying chromosomal subpopulations based on their recombination histories advances the study of the genetic basis of phenotypic traits
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    “…In this work, we combine gene expression, in vivo reporter assays, CRISPR/Cas9 genome editing, and survival experiments to characterize in detail the molecular and phenotypic consequences of a natural Drosophila melanogaster transposable element insertion: the roo solo-LTR FBti0019985. …”
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    The Interplay Between Developmental Stage and Environment Underlies the Adaptive Effect of a Natural Transposable Element Insertion
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