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1por Bakal, David, Coelho, Lara, Luz, Paula M, Clark, Jesse L, De Boni, Raquel, Cardoso, Sandra Wagner, Veloso, Valdilea, Lake, Jordan, Grinsztejn, Beatriz“…BACKGROUND: Weight gain commonly occurs among HIV-infected (HIV+) adults initiating modern ART regimens, and obesity is increasingly reported in this population. …”
Publicado 2017
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2por Coelho, Lara E., Jenkins, Cathy A., Shepherd, Bryan E., Pape, Jean W., Cordero, Fernando Mejia, Padgett, Denis, Ramirez, Brenda Crabtree, Grinsztejn, Beatriz, Althoff, Keri N., Koethe, John R., Marconi, Vincent C., Tien, Phyllis C., Willig, Amanda L., Moore, Richard D., Castilho, Jessica L., Colasanti, Jonathan, Crane, Heidi M., Gill, M. John, Horberg, Michael A., Mayor, Angel, Silverberg, Michael J., McGowan, Catherine, Rebeiro, Peter F.“…METHODS: ART-naïve PWH ≥18 years old, enrolled in Brazil, Honduras, Mexico, Peru, and Haiti (sites within CCASAnet) and the US (NA-ACCORD) starting ART between 2000 and 2017, with at least one weight measured after ART initiation were included. …”
Publicado 2022
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3por Carriquiry, Gabriela, Giganti, Mark J, Castilho, Jessica L, Jayathilake, Karu, Cahn, Pedro, Grinsztejn, Beatriz, Cortes, Claudia, Pape, Jean W, Padgett, Denis, Sierra‐Madero, Juan, McGowan, Catherine C, Shepherd, Bryan E, Gotuzzo, Eduardo“…Patients were classified as older (≥50 years) or younger (<50 years) based on age at ART initiation. ART effectiveness was measured using three outcomes: death, virologic failure and ART treatment modification. …”
Publicado 2018
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4por Caetano, Diogo Gama, Ribeiro-Alves, Marcelo, Hottz, Eugênio Damaceno, Vilela, Larissa Melo, Cardoso, Sandra Wagner, Hoagland, Brenda, Grinsztejn, Beatriz, Veloso, Valdilea Gonçalves, Morgado, Mariza Gonçalves, Bozza, Patrícia Torres, Guimarães, Monick Lindenmeyer, Côrtes, Fernanda Heloise“…We observed the highest frequencies of activated CD8(+) T cells in VCs, while EC and cART groups presented similar but slightly altered frequencies of this marker when compared to the HIVneg group. …”
Publicado 2022
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5por de Paula, Hury Hellen Souza, Ferreira, Ana Cristina Garcia, Caetano, Diogo Gama, Delatorre, Edson, Teixeira, Sylvia Lopes Maia, Coelho, Lara Esteves, João, Eduarda Grinsztejn, de Andrade, Michelle Morata, Cardoso, Sandra Wagner, Grinsztejn, Beatriz, Veloso, Valdilea Gonçalves, Morgado, Mariza Gonçalves, Guimarães, Monick Lindenmeyer, Côrtes, Fernanda Heloise“…OBJECTIVES: To investigate the impact of early combined antiretroviral therapy (cART) on inflammation biomarkers and immune activation during acute and early chronic HIV-1 infection. …”
Publicado 2018
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6por Leite, Thaysse Ferreira, Delatorre, Edson, Côrtes, Fernanda Heloise, Ferreira, Ana Cristina Garcia, Cardoso, Sandra Wagner, Grinsztejn, Beatriz, de Andrade, Michelle Morata, Veloso, Valdilea Gonçalves, Morgado, Mariza Gonçalves, Guimarães, Monick Lindenmeyer“…Peripheral blood mononuclear cell (PBMC) and plasma samples were obtained from ten HIV-infected Brazilian individuals diagnosed at the acute phase of infection, before (PRE(ART)) and 12 months (M12(ART)) after suppressive cART. …”
Publicado 2019
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7Materias: “…PrEP Implementation Science: State-of-the-Art and Research Agenda…”
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8por Luz, Paula M, Girouard, Michael P, Grinsztejn, Beatriz, Freedberg, Kenneth A, Veloso, Valdilea G, Losina, Elena, Struchiner, Claudio J, MacLean, Rachel L, Parker, Robert A, Paltiel, A David, Walensky, Rochelle P“…OBJECTIVE: In Brazil, universal provision of antiretroviral therapy (ART) has been guaranteed free of charge to eligible HIV-positive patients since December 1996. …”
Publicado 2016
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9por Cardoso, Sandra W, Luz, Paula M, Velasque, Luciane, Torres, Thiago S, Tavares, Isabel C, Ribeiro, Sayonara R, Moreira, Ronaldo I, Veloso, Valdilea G, Moore, Richard D, Grinsztejn, Beatriz“…For this study we included all patients who started first-line and second-line cART between 2000 and 2013. Second-line cART required a switch in the anchor drug of first-line cART. …”
Publicado 2014
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10por Carriquiry, Gabriela, Fink, Valeria, Koethe, John Robert, Giganti, Mark Joseph, Jayathilake, Karu, Blevins, Meridith, Cahn, Pedro, Grinsztejn, Beatriz, Wolff, Marcelo, Pape, Jean William, Padgett, Denis, Madero, Juan Sierra, Gotuzzo, Eduardo, McGowan, Catherine Carey, Shepherd, Bryan Earl“…Risk factors for death were assessed using Cox regression models stratified by site and adjusted for sex, baseline age, nadir pre-ART CD4 count, calendar year of ART initiation, clinical AIDS at baseline and type of ART regimen. …”
Publicado 2015
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11por Calvet, Guilherme Amaral, Velasque, Luciane, Luz, Paula Mendes, Cardoso, Sandra Wagner, Derrico, Monica, Moreira, Ronaldo Ismério, de Andrade, Angela Cristina Vasconcelos, Cytryn, Andrea, Pires, Elaine, Veloso, Valdiléa Gonçalves, Grinsztejn, Beatriz, Friedman, Ruth Khalili“…METHODS: ART-naïve women initiating cART between January 2000/June 2010 at the Instituto de Pesquisa Clínica Evandro Chagas Cohort were studied. …”
Publicado 2014
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12por Castilho, Jessica L, Kim, Ahra, Jenkins, Cathy A, Grinsztejn, Beatriz, Gotuzzo, Eduardo, Fink, Valeria, Padgett, Denis, Belaunzaran‐Zamudio, Pablo F, Crabtree‐Ramírez, Brenda, Escuder, Maria Mercedes, Souza, Rosa Alencar, Tenore, Simone B, Pimentel, Sidnei R, Ikeda, Maria Letícia Rodrigues, de Alencastro, Paulo R, Tupinanbas, Unai, Brites, Carlos, Luz, Estela, Netto, Juliana, Cortes, Claudia P, Grangeiro, Alexandre, Shepherd, Bryan E, McGowan, Catherine C“…Since 2010, the adjusted risk of KS increased in the periods before and ≤90 days after ART initiation but decreased >90 days after ART. …”
Publicado 2021
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13por Coelho, Lara E., Cardoso, Sandra W., Amancio, Rodrigo T., Moreira, Ronaldo I., Ribeiro, Sayonara R., Coelho, Alessandra B., Campos, Dayse P., Veloso, Valdiléa G., Grinsztejn, Beatriz, Luz, Paula M.“…CONCLUSIONS: Our findings show that, still in the post-cART era, prevention of opportunistic infections can be achieved by preventing immune deterioration by instituting early use of cART. …”
Publicado 2016
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14por Cardoso, Sandra W, Luz, Paula M, Velasque, Luciane, Torres, Thiago, Coelho, Lara, Freedberg, Kenneth A, Veloso, Valdilea G, Walensky, Rochelle P, Grinsztejn, Beatriz“…BACKGROUND: While Brazil has had a long-standing policy of free access to antiretroviral therapy (ART) for all in need, the epidemiological impact of ART on human immunodeficiency virus (HIV) RNA suppression in this middle-income country has not been well evaluated. …”
Publicado 2014
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15por Luz, Paula M., Grinsztejn, Beatriz, Velasque, Luciane, Pacheco, Antonio G., Veloso, Valdilea G., Moore, Richard D., Struchiner, Claudio J.“…Inverse probability of censoring weighting was used to estimate mean annual CD4+ cell counts while adjusting for choice of initial ART regimen, ART discontinuation and losses-to-follow-up. …”
Publicado 2014
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16por Grangeiro, Alexandre, Escuder, Maria Mercedes, Cassanote, Alex Jones Flores, Souza, Rosa Alencar, Kalichman, Artur O., Veloso, Valdiléa, Ikeda, Maria Letícia Rodrigues, Barcellos, Nêmora Tregnago, Brites, Carlos, Tupinanbás, Unai, Lucena, Noaldo O., da Silva, Carlos Lima, Lacerda, Heloisa Ramos, Grinsztejn, Beatriz, Castilho, Euclides Ayres“…The study design, patients’ profiles and characteristics of cART initiation between 2003 and 2010 were described. …”
Publicado 2014
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17por Palumbo, Philip J., Wilson, Ethan A., Piwowar-Manning, Estelle, McCauley, Marybeth, Gamble, Theresa, Kumwenda, Newton, Makhema, Joseph, Kumarasamy, Nagalingeswaran, Chariyalertsak, Suwat, Hakim, James G., Hosseinipour, Mina C., Melo, Marineide G., Godbole, Sheela V., Pilotto, Jose H., Grinsztejn, Beatriz, Panchia, Ravindre, Chen, Ying Q., Cohen, Myron S., Eshleman, Susan H., Fogel, Jessica M.“…Higher HIV diversity has been associated with virologic outcomes in children on antiretroviral treatment (ART). We examined the association of HIV diversity with virologic outcomes in adults from the HPTN 052 trial who initiated ART at CD4 cell counts of 350–550 cells/mm(3). …”
Publicado 2017
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18“…Currently, immediate initiation of antiretroviral therapy (ART) is recommended for all individuals with HIV infection. …”
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19por Diaz, Chanelle M., Segura, Eddy R., Luz, Paula M., Clark, Jesse L., Ribeiro, Sayonara R., De Boni, Raquel, Eksterman, Leonardo, Moreira, Rodrigo, Currier, Judith S., Veloso, Valdiléa G., Grinsztejn, Beatriz, Lake, Jordan E.“…BACKGROUND: Antiretroviral therapy (ART) agents potentially associated with adverse metabolic profiles are commonly used in low- and middle-income countries. …”
Publicado 2016
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20por Caro-Vega, Yanink, Belaunzarán-Zamudio, Pablo F, Crabtree-Ramírez, Brenda E, Shepherd, Bryan E, Grinsztejn, Beatriz, Wolff, Marcelo, Pape, Jean W, Padgett, Denis, Gotuzzo, Eduardo, McGowan, Catherine C, Sierra-Madero, Juan G“…METHODS: We included ART-naïve, HIV-positive adults on EFV or bPIs as firstline ART in CCASAnet between 2000 and 2016. …”
Publicado 2018
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