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1por van Henten, Saskia, Adriaensen, Wim, Fikre, Helina, Akuffo, Hannah, Diro, Ermias, Hailu, Asrat, Van der Auwera, Gert, van Griensven, Johan“…Leishmania aethiopica is the main causative species for cutaneous leishmaniasis (CL) in Ethiopia. Despite its considerable burden, L. aethiopica has been one of the most neglected Leishmania species. …”
Publicado 2019
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2“…Half a million new cases of visceral leishmaniasis occur each year, and 10% of these are fatal. …”
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3por Diro, Ermias, Lynen, Lutgarde, Ritmeijer, Koert, Boelaert, Marleen, Hailu, Asrat, van Griensven, Johan“…Visceral Leishmaniasis (VL) is an important protozoan opportunistic disease in HIV patients in endemic areas. …”
Publicado 2014
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4por Wasunna, Monique, Musa, Ahmed, Hailu, Asrat, Khalil, Eltahir A. G., Olobo, Joseph, Juma, Rashid, Wells, Susan, Alvar, Jorge, Balasegaram, Manica“…Visceral leishmaniasis is a neglected tropical disease endemic in East Africa where improved patient-adapted treatments are needed. …”
Publicado 2016
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6por Müller, Ingrid, Hailu, Asrat, Choi, Beak-San, Abebe, Tamrat, Fuentes, Jose M., Munder, Markus, Modolell, Manuel, Kropf, Pascale“…Thus, targeting L-arginine metabolism might be a promising therapeutic strategy against leishmaniasis, especially in children and young adults.…”
Publicado 2008
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7por Lemma, Wossenseged, Erenso, Girume, Gadisa, Endalamaw, Balkew, Meshesha, Gebre-Michael, Teshome, Hailu, Asrat“…BACKGROUND: Cutaneous leishmaniasis (CL) is endemic in the highlands of Ethiopia, and almost always caused by Leishmania aethiopica. …”
Publicado 2009
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8por Takele, Yegnasew, Abebe, Tamrat, Weldegebreal, Teklu, Hailu, Asrat, Hailu, Workagegnehu, Hurissa, Zewdu, Ali, Jemal, Diro, Ermiyas, Sisay, Yifru, Cloke, Tom, Modolell, Manuel, Munder, Markus, Tacchini-Cottier, Fabienne, Müller, Ingrid, Kropf, Pascale“…BACKGROUND: Visceral leishmaniasis is a parasitic disease associated with high mortality. …”
Publicado 2013
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9por Abebe, Tamrat, Hailu, Asrat, Woldeyes, Mihretu, Mekonen, Woinshet, Bilcha, Kassahun, Cloke, Thomas, Fry, Lionel, Seich al Basatena, Nafisa-Katrin, Corware, Karina, Modolell, Manuel, Munder, Markus, Tacchini-Cottier, Fabienne, Müller, Ingrid, Kropf, Pascale“…BACKGROUND: Cutaneous leishmaniasis is a vector-borne disease that is in Ethiopia mainly caused by the parasite Leishmania aethiopica. …”
Publicado 2012
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10Correction: Arginase Activity in the Blood of Patients with Visceral Leishmaniasis and HIV Infectionpor Takele, Yegnasew, Abebe, Tamrat, Weldegebreal, Teklu, Hailu, Asrat, Hailu, Workagegnehu, Hurissa, Zewdu, Ali, Jemal, Diro, Ermiyas, Sisay, Yifru, Cloke, Tom, Modolell, Manuel, Munder, Markus, Tacchini-Cottier, Fabienne, Müller, Ingrid, Kropf, PascaleEnlace del recurso
Publicado 2013
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11por Vallur, Aarthy C., Tutterrow, Yeung L., Mohamath, Raodoh, Pattabhi, Sowmya, Hailu, Asrat, Abdoun, Asim O., Ahmed, Abdalla E., Mukhtar, Maowia, Salam, Md Abdus, Almeida, Meirielly Lima, Almeida, Roque P., Mondal, Dinesh, Albertini, Audrey, Ghalib, Hashim, Duthie, Malcolm S., Reed, Steven G.“…BACKGROUND: Visceral leishmaniasis (VL) can be fatal without timely diagnosis and treatment. …”
Publicado 2015
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12por van Griensven, Johan, Gadisa, Endalamaw, Aseffa, Abraham, Hailu, Asrat, Beshah, Abate Mulugeta, Diro, Ermias“…Leishmania aethiopica is the etiological agent of cutaneous leishmaniasis (CL) in Ethiopia and can cause severe and complicated cases such as diffuse CL (DCL), mucocutaneous leishmaniasis or extensive CL, requiring systemic treatment. …”
Publicado 2016
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13por Alebie, Getachew, Worku, Amha, Yohannes, Siele, Urga, Befikadu, Hailu, Asrat, Tadesse, Dagimawie“…BACKGROUND: Visceral leishmaniasis (VL), a vector-borne disease caused by species of the L.donovani complex, has (re)-emerged in Ethiopia during the last two decades and is currently of increasing public health concern. …”
Publicado 2019
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14por Abebe, Tamrat, Takele, Yegnasew, Weldegebreal, Teklu, Cloke, Tom, Closs, Ellen, Corset, Camille, Hailu, Asrat, Hailu, Workagegnehu, Sisay, Yifru, Corware, Karina, Corset, Margaux, Modolell, Manuel, Munder, Markus, Tacchini-Cottier, Fabienne, Müller, Ingrid, Kropf, Pascale“…The underlying mechanisms resulting in the profound immune suppression characteristic of human visceral leishmaniasis (VL) are not fully understood. Here, we tested the hypothesis that arginase, an enzyme associated with immunosuppression, is higher in patients with VL and contributes to impaired T cell responses. …”
Publicado 2013
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15por Miller, Ezer, Warburg, Alon, Novikov, Ilya, Hailu, Asrat, Volf, Petr, Seblova, Veronika, Huppert, Amit“…Identifying the hosts that contribute most towards infection of the vectors is crucial for understanding the transmission dynamics, and planning targeted intervention policy of visceral leishmaniasis as well as other vector borne infectious diseases (e.g., West Nile Fever).…”
Publicado 2014
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16por Tajebe, Fitsumbrhan, Getahun, Mulusew, Adem, Emebet, Hailu, Asrat, Lemma, Mulualem, Fikre, Helina, Raynes, John, Tamiru, Aschalew, Mulugeta, Zemenay, Diro, Ermias, Toulza, Frederic, Shkedy, Ziv, Ayele, Tadesse, Modolell, Manuel, Munder, Markus, Müller, Ingrid, Takele, Yegnasew, Kropf, Pascale“…Visceral leishmaniasis (VL) is a neglected tropical disease that affects the poorest communities and can cause substantial morbidity and mortality. …”
Publicado 2017
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17por Modolell, Manuel, Choi, Beak-San, Ryan, Robert O., Hancock, Maggie, Titus, Richard G., Abebe, Tamrat, Hailu, Asrat, Müller, Ingrid, Rogers, Matthew E., Bangham, Charles R. M., Munder, Markus, Kropf, Pascale“…The balance between T helper (Th) 1 and Th2 cell responses is a major determinant of the outcome of experimental leishmaniasis, but polarized Th1 or Th2 responses are not sufficient to account for healing or nonhealing. …”
Publicado 2009
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18por Van den Bergh, Rafael, Van Ginderachter, Jo A., Schouppe, Elio, Desimmie, Belete A., Hailu, Asrat, De Baetselier, Patrick, van Griensven, JohanEnlace del recurso
Publicado 2014
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19por Yared, Solomon, Deribe, Kebede, Gebreselassie, Araya, Lemma, Wessenseged, Akililu, Essayas, Kirstein, Oscar D, Balkew, Meshesha, Warburg, Alon, Gebre-Michael, Teshome, Hailu, Asrat“…BACKGROUND: Visceral leishmaniasis (VL, also called ‘’kala-azar”), is a life threatening neglected tropical infectious disease which mainly affects the poorest of the poor. …”
Publicado 2014
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20por Musa, Ahmed M., Younis, Brima, Fadlalla, Ahmed, Royce, Catherine, Balasegaram, Manica, Wasunna, Monique, Hailu, Asrat, Edwards, Tansy, Omollo, Raymond, Mudawi, Mahmoud, Kokwaro, Gilbert, El-Hassan, Ahmed, Khalil, Eltahir“…BACKGROUND: A recent study has shown that treatment of visceral leishmaniasis (VL) with the standard dose of 15 mg/kg/day of paromomycin sulphate (PM) for 21 days was not efficacious in patients in Sudan. …”
Publicado 2010
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