Mostrando 1 - 16 Resultados de 16 Para Buscar '"The Messengers"', tiempo de consulta: 1.84s Limitar resultados
  1. 1
    “…N(6)-methyladenosine (m(6)A) is the most prevalent internal (non-cap) modification present in the messenger RNA (mRNA) of all higher eukaryotes(1,2). …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    m(6)A-dependent regulation of messenger RNA stability
  2. 2
    “…Chemical modifications on messenger RNA are increasingly recognized as a critical regulatory layer in the flow of genetic information, but quantitative tools to monitor RNA modifications in a whole-transcriptome and site-specific manner are lacking. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Evolution of a Reverse Transcriptase to Map N(1)-Methyladenosine in Human mRNA
  3. 3
    “…N(6)-methyladenosine (m(6)A) is the most prevalent and reversible internal modification in mammalian messenger and non-coding RNAs. We report here that human METTL14 catalyzes m(6)A RNA methylation. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    A METTL3-METTL14 complex mediates mammalian nuclear RNA N(6)-adenosine methylation
  4. 4
    por Yue, Yanan, Liu, Jianzhao, He, Chuan
    Publicado 2015
    “…N(6)-methyladenosine (m(6)A) is the most prevalent and internal modification that occurs in the messenger RNAs (mRNA) of most eukaryotes, although its functional relevance remained a mystery for decades. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    RNA N(6)-methyladenosine methylation in post-transcriptional gene expression regulation
  5. 5
    “…Here we show that over one-third of zebrafish maternal messenger RNAs (mRNAs) can be N(6)-methyladenosine (m(6)A) modified, and the clearance of these maternal mRNAs is facilitated by an m(6)A-binding protein, Ythdf2. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    m(6)A-dependent maternal mRNA clearance facilitates zebrafish maternal-to-zygotic transition
  6. 6
    “…Recent discoveries of reversible N(6)-methyladenosine (m(6)A) methylation on messenger RNA (mRNA) and mapping of m(6)A methylomes in mammals and yeast have revealed potential regulatory functions of this RNA modification. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Unique Features of the m(6)A Methylome in Arabidopsis thaliana
  7. 7
    “…N(6)-methyladenosine (m(6)A) is the most abundant internal modification of eukaryotic messenger RNA (mRNA) and plays critical roles in RNA biology. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    YTHDC1 mediates nuclear export of N(6)-methyladenosine methylated mRNAs
  8. 8
    “…Chemical modifications of messenger RNA (mRNA) may regulate many aspects of mRNA processing and protein synthesis. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    2′-O-methylation in mRNA disrupts tRNA decoding during translation elongation
  9. 9
    “…N (6)-methyladenosine (m(6)A) is the most prevalent modification in eukaryotic messenger RNAs (mRNAs) and is interpreted by its readers, such as YTH domain-containing proteins, to regulate mRNA fate. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Recognition of RNA N(6)-methyladenosine by IGF2BP Proteins Enhances mRNA Stability and Translation
  10. 10
    “…Here, we show that durable neoantigen-specific immunity is regulated by messenger RNA (mRNA) N(6)-methyadenosine (m(6)A) methylation through the m(6)A-binding protein YTHDF1(5). …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Anti-tumor immunity controlled through mRNA m(6)A and YTHDF1 in dendritic cells
  11. 11
    “…N(6)-methyladenosine (m(6)A) is one of the most abundant messenger RNA modifications in eukaryotes involved in various pivotal processes of RNA metabolism. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Single-base mapping of m(6)A by an antibody-independent method
  12. 12
    “…The regulation of islet cell biology is critical for glucose homeostasis(1).N(6)-methyladenosine (m(6)A) is the most abundant internal messenger RNA (mRNA) modification in mammals(2). Here we report that the m(6)A landscape segregates human type 2 diabetes (T2D) islets from controls significantly better than the transcriptome and that m(6)A is vital for β-cell biology. m(6)A-sequencing in human T2D islets reveals several hypomethylated transcripts involved in cell-cycle progression, insulin secretion, and the Insulin/IGF1-AKT-PDX1 pathway. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    m(6)A mRNA Methylation Regulates Human β-Cell Biology in Physiological States and in Type 2 Diabetes
  13. 13
    “…N(6)-methyladenosine (m(6)A) is the most abundant internal modification in eukaryotic messenger RNA (mRNA). Recent discoveries of demethylases and specific binding proteins of m(6)A as well as m(6)A methylomes obtained in mammals, yeast and plants have revealed regulatory functions of this RNA modification. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Widespread occurrence of N(6)-methyladenosine in bacterial mRNA
  14. 14
    “…N(6)-methyladenosine (m(6)A), the most abundant and dynamic internal modification in eukaryotic messenger RNA(8-19), can be selectively recognized by the YTHDF2 protein to affect the stability of cytoplasmic mRNAs(15), but how m(6)A achieves wide-ranging physiological significance needs further exploration. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    N(6)-methyladenosine-dependent RNA structural switches regulate RNA-protein interactions
  15. 15
    “…N(6)-methyladenosine (m(6)A), the most prevalent internal RNA modification on mammalian messenger RNAs (mRNAs), regulates fates and functions of modified transcripts through m(6)A-specific binding proteins(1–5). m(6)A is abundant in the nervous system and modulates various neural functions(6–11). …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    m(6)A facilitates hippocampus-dependent learning and memory through Ythdf1
  16. 16
    “…RESULTS: In total, 1,398 lncRNAs and 14,631 messenger RNAs were screened from TCGA data set, and divided into the low and high immunity groups. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Screening and verification of prognostic lncRNA markers related to immune infiltration in the metastasis of osteosarcoma
Herramientas de búsqueda: RSS