Mostrando 1 - 20 Resultados de 35 Para Buscar '"The OA"', tiempo de consulta: 0.22s Limitar resultados
  1. 1
    “…BACKGROUND: Hip effusion-synovitis may be relevant to osteoarthritis (OA) but is of uncertain etiology. The aim of this study was to describe the cross-sectional and longitudinal associations of hip effusion-synovitis with clinical and structural risk factors of OA in older adults. …”
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    Quantification of hip effusion-synovitis and its cross-sectional and longitudinal associations with hip pain, MRI findings and early radiographic hip OA
  2. 2
    “…A variant in the FTO gene has been implicated in genetic risk to osteoarthritis (OA). We examined the role of the FTO polymorphism rs8044769 in risk of knee and hip OA in cases and controls incorporating body mass index (BMI) information. …”
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    The effect of FTO variation on increased osteoarthritis risk is mediated through body mass index: a mendelian randomisation study
  3. 3
    “…Osteoarthritis (OA) mainly affects older populations; however, it is possible that early life factors contribute to the development of OA in later life. …”
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    Do early life factors affect the development of knee osteoarthritis in later life: a narrative review
  4. 4
    “…OBJECTIVE: To assess if a coding variant in the gene encoding transient receptor potential cation channel, subfamily V, member 1 (TRPV1) is associated with genetic risk of painful knee osteoarthritis (OA). METHODS: The Ile585Val TRPV1 variant encoded by rs8065080 was genotyped in 3270 cases of symptomatic knee OA, 1098 cases of asymptomatic knee OA and 3852 controls from seven cohorts from the UK, the USA and Australia. …”
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    The Ile585Val TRPV1 variant is involved in risk of painful knee osteoarthritis
  5. 5
    “…BACKGROUND: Osteoarthritis (OA) is a major clinical and public health problem, with no current medications approved as having disease modifying effects. …”
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    Does statin use have a disease modifying effect in symptomatic knee osteoarthritis? Study protocol for a randomised controlled trial
  6. 6
    “…Osteoarthritis (OA) is a common joint disorder for which there is no cure. …”
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    A Randomised Controlled Trial of YOGa and Strengthening Exercise for Knee OsteoArthritis: Protocol for a Comparative Effectiveness Trial (YOGA Trial)
  7. 7
    “…BACKGROUND: Osteoarthritis (OA) is a common health issue worldwide in the aging population who are also commonly deficient in vitamin D. …”
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    Vitamin D supplementation in the management of knee osteoarthritis: study protocol for a randomized controlled trial
  8. 8
    “…Recent meta-analyses have shown a range of effects of OA on mortality, reflecting different OA definitions and study methods. …”
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    Knee osteoarthritis and time-to all-cause mortality in six community-based cohorts: an international meta-analysis of individual participant-level data
  9. 9
    “…BACKGROUND: There is an unmet need for treatments for knee osteoarthritis (OA). Effusion-synovitis is a common inflammatory phenotype of knee OA and predicts knee pain and structural degradation. …”
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    Study protocol for a randomised controlled trial of diacerein versus placebo to treat knee osteoarthritis with effusion-synovitis (DICKENS)
  10. 10
    “…BACKGROUND: Cam morphology contributes to the development of hip osteoarthritis (OA) but is less studied in the general population. …”
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    A prospective cohort study on cam morphology and its role in progression of osteoarthritis
  11. 11
    “…OBJECTIVE: With adults working to older ages, occupation is an important, yet less modifiable domain of physical activity to consider in the risk of knee osteoarthritis (OA). This study aimed to investigate the association between predominant lifetime occupation and prevalent knee OA. …”
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    Predominant lifetime occupation and associations with painful and structural knee osteoarthritis: An international participant-level cohort collaboration
  12. 12
    “…BACKGROUND: Bisphosphonates are a class of drugs that slow bone loss and are a promising candidate to treat knee osteoarthritis (OA) patients. In a pilot study, we demonstrated that zoledronic acid reduced knee pain and size of subchondral bone marrow lesions (BMLs) over 6 months in knee OA patients with significant knee pain and BMLs. …”
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    A protocol for a multicentre, randomised, double-blind, placebo-controlled trial to compare the effect of annual infusions of zoledronic acid to placebo on knee structural change and knee pain over 24 months in knee osteoarthritis patients – ZAP2
  13. 13
    “…OBJECTIVE: There is increasing evidence for the involvement of vascular disease in the pathogenesis of knee OA. Popliteal artery wall thickness can be used as a surrogate marker of atherosclerosis. …”
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    Association between popliteal artery wall thickness and structural progression in patients with symptomatic knee osteoarthritis
  14. 14
    “…BACKGROUND: Previous studies investigating the association between GDF5 rs143383 polymorphism and knee osteoarthritis (OA) have suggested stronger associations in Asians than Caucasians, but limitations on the amount of available data have meant that a definitive assessment has not been possible. …”
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    Association between GDF5 rs143383 polymorphism and knee osteoarthritis: an updated meta-analysis based on 23,995 subjects
  15. 15
    “…OBJECTIVE: To evaluate the effects of the updated version of an evidence-based osteoarthritis (OA) resource and consumer hub, ‘My Joint Pain’ website, on health education and quality of care over 12 months. …”
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    My joint pain, a web-based resource, effects on education and quality of care at 24 months
  16. 16
    “…CONCLUSION: Change in meniscal tears shares risk factors with knee OA and is independently associated with worsening knee pain and structural damage suggesting that meniscal tears are on the knee OA causal pathway.…”
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    Natural history and clinical significance of meniscal tears over 8 years in a midlife cohort
  17. 17
    “…BACKGROUND: To describe demographic and clinical factors associated with the presence and incidence of depression and explore the temporal relationship between depression and joint symptoms in patients with symptomatic knee osteoarthritis (OA). METHODS: Three hundred ninety-seven participants were selected from a randomized controlled trial in people with symptomatic knee OA and vitamin D deficiency (age 63.3 ± 7.1 year, 48.6% female). …”
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    Depression in patients with knee osteoarthritis: risk factors and associations with joint symptoms
  18. 18
    “…The objective of this study was to describe the rate of change in knee cartilage volume over 4.5 years in subjects with symptomatic knee osteoarthritis (OA) and to determine factors associated with cartilage loss. …”
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    Knee cartilage loss in symptomatic knee osteoarthritis over 4.5 years
  19. 19
    “…This suggests a gap in knowledge for persons with OA regarding the many different treatments available to them. …”
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    The Web-Based Osteoarthritis Management Resource My Joint Pain Improves Quality of Care: A Quasi-Experimental Study
  20. 20
    “…INTRODUCTION: The associations between leptin, interleukin (IL)-6, and hip radiographic osteoarthritis (OA) have not been reported, and their roles in obesity-related hip OA are unclear. …”
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    The association between leptin, interleukin-6, and hip radiographic osteoarthritis in older people: a cross-sectional study
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