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1por Liu, Fang, Liang, Tian, Zhang, Zhiying, Liu, Lijun, Li, Jing, Dong, Wenxue, Zhang, Han, Bai, Su, Ma, Lifeng, Kang, Longli“…Only a few studies have focused on the characteristics of oral microbiota in high-altitude humans. We collected saliva samples from 167 Tibetans at four altitudes (2800 to 4500 m) in Tibet to explore the relationship between the high altitude environment and oral microbiota. …”
Publicado 2021
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2por Feng, Siwei, Wei, Gang, Yang, Xuelin, Zhang, Zhiying, Qu, Jingfeng, Wang, Donglan, Zhou, Tian, Ni, Ting, Liu, Lijun, Kang, Longli“…BACKGROUND: As a chronic mountain sickness(CMS) with the highest incidence and the greatest harm, the pathogenesis of high altitude polycythemia (HAPC) is still not fully understood. …”
Publicado 2023
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3por Zhang, Zhiying, Ma, Lifeng, Fan, Xiaowei, Wang, Kun, Liu, Lijun, Zhao, Yiduo, Zhao, ZhiPeng, Zhang, Han, Liang, Tian, Dong, Wenxue, Cai, Peng, Li, Yansong, Li, Jing, Zhou, Songhua, Kang, Longli“…High-altitude polycythemia (HAPC) is characterized by excessive proliferation of erythrocytes, resulting from the hypobaric hypoxia condition in high altitude. …”
Publicado 2021
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4por Li, Yi, Hao, Meng, Hu, Zixin, Ma, Yanyun, Wang, Kun, Liu, Xiaoyu, Yin, Xianhong, Zhang, Menghan, Wang, Yi, Liang, Meng, Guo, Yuan, Bao, Lei, Zhang, Shixuan, Le, Shiguan, Wu, Chenyuan, Sun, Dayan, Wei, Yang, Wu, Fei, Zhang, Rui, Zhu, Lingxian, Zhang, Hui, Jiang, Shuai, Chen, Xingdong, Wang, Xiaofeng, Zhang, Yao, Kang, Longli, Duan, Wenyuan, Qiao, Bin, Wang, Jiucun, Jin, LiEnlace del recurso
Publicado 2023
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5por Jin, Tianbo, Ren, Yongchao, Zhu, Xikai, Li, Xun, Ouyang, Yongri, He, Xue, Zhang, Zhiying, Zhang, Yuan, Kang, Longli, Yuan, Dongya“…Previous studies demonstrated that Angiotensin II Receptor 1 (AGTR1) may play an important role in the development of high-altitude pulmonary edema. We envisaged a role for AGTR1 gene variants in the pathogenesis of HAPE and investigated their potential associations with HAPE in a Han Chinese population. …”
Publicado 2016
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6por Li, Xun, Jin, Tianbo, Zhang, Mingxia, Yang, Hua, Huang, Xuewen, Zhou, Xiaobo, Huang, Wenchao, Qin, Lipeng, Kang, Longli, Fan, Ming, Li, Suzhi“…A two-stage genome-wide association study (GWAS) was performed to identify and analyze genes and single nucleotide polymorphisms (SNPs) associated with high-altitude pulmonary edema (HAPE) in a Han Chinese patient population. …”
Publicado 2017
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7por Liu, Lijun, Zhang, Yao, Zhang, Zhiying, Zhao, Yiduo, Fan, Xiaowei, Ma, Lifeng, Zhang, Yuan, He, Haijin, Kang, Longli“…High altitude polycythemia (HAPC) refers to the long-term living in the plateau of the hypoxia environment is not accustomed to cause red blood cell hyperplasia. …”
Publicado 2017
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8por Fan, Xiaowei, Ma, Lifeng, Zhang, Zhiying, Li, Yi, Hao, Meng, Zhao, Zhipeng, Zhao, Yiduo, Liu, Fang, Liu, Lijun, Luo, Xingguang, Cai, Peng, Li, Yansong, Kang, Longli“…BACKGROUND: High-altitude polycythemia (HAPC) is a chronic high-altitude disease that can lead to an increase in the production of red blood cells in the people who live in the plateau, a hypoxia environment, for a long time. …”
Publicado 2018
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9por Zhao, Yiduo, Zhang, Zhiying, Liu, Lijun, Zhang, Yao, Fan, Xiaowei, Ma, Lifeng, Li, Jing, Zhang, Yuan, He, Haijin, Kang, Longli“…High altitude polycythemia (HAPC) is a common chronic disease at high altitude, which is characterized by excessive erythrocytosis (females, hemoglobin ≥ 190 g/L; males, hemoglobin ≥ 210 g/L). …”
Publicado 2017
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10por Li, Yi, Ma, Yanyun, Wang, Kun, Zhang, Menghan, Wang, Yi, Liu, Xiaoyu, Hao, Meng, Yin, Xianhong, Liang, Meng, Zhang, Hui, Wang, Xiaofeng, Chen, Xingdong, Zhang, Yao, Duan, Wenyuan, Kang, Longli, Qiao, Bin, Wang, Jiucun, Jin, Li“…Altitude acclimatization is a human physiological process of adjusting to the decreased oxygen availability. …”
Publicado 2021
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11por Wang, Kun, Zhang, Menghan, Li, Yi, Pu, Weilin, Ma, Yanyun, Wang, Yi, Liu, Xiaoyu, Kang, Longli, Wang, Xiaofeng, Wang, Jiucun, Qiao, Bin, Jin, Li“…BACKGROUND: High-altitude headache (HAH) is the most common sickness occurred in healthy people after rapid ascending to high altitude, and its risk factors were still not well understood. …”
Publicado 2018
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12por He, Yongjun, Liu, Lijun, Xu, Pengcheng, He, Na, Yuan, Dongya, Kang, Longli, Jin, Tianbo“…High altitude pulmonary edema (HAPE) occurs mainly under conditions such as high altitude, rapid ascent, or hypoxia. …”
Publicado 2017
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13por Dong, Wenxue, Ma, Lifeng, Huang, Qiumin, Yang, Xu, Mei, Zhendong, Kong, Mengmeng, Sun, Zhonghan, Zhang, Zhiying, Li, Jing, Zou, Jiaojiao, Chen, Dandan, Dai, Yuxiang, Zhou, Daxin, Zheng, Yan, Kang, Longli“…BACKGROUND: Alterations in the gut microbiota have been observed in patients with pulmonary hypertension (PH), though whether the roles of the gut microbiota in PH at different altitudes are the same is unknown. This study aims to evaluate the associations of the gut microbiome with PH in highlanders and lowlanders. …”
Publicado 2023
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14por Zhang, Chao, Lu, Yan, Feng, Qidi, Wang, Xiaoji, Lou, Haiyi, Liu, Jiaojiao, Ning, Zhilin, Yuan, Kai, Wang, Yuchen, Zhou, Ying, Deng, Lian, Liu, Lijun, Yang, Yajun, Li, Shilin, Ma, Lifeng, Zhang, Zhiying, Jin, Li, Su, Bing, Kang, Longli, Xu, Shuhua“…To gain insights into the population history and the genetic basis of high-altitude adaptation of the two groups, we analyzed genome-wide data in 111 Sherpas (Tibet and Nepal) and 177 Tibetans (Tibet and Qinghai), together with available data from present-day human populations. …”
Publicado 2017
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15por Deng, Lian, Zhang, Chao, Yuan, Kai, Gao, Yang, Pan, Yuwen, Ge, Xueling, He, Yaoxi, Yuan, Yuan, Lu, Yan, Zhang, Xiaoxi, Chen, Hao, Lou, Haiyi, Wang, Xiaoji, Lu, Dongsheng, Liu, Jiaojiao, Tian, Lei, Feng, Qidi, Khan, Asifullah, Yang, Yajun, Jin, Zi-Bing, Yang, Jian, Lu, Fan, Qu, Jia, Kang, Longli, Su, Bing, Xu, Shuhua“…Human genetic adaptation to high altitudes (>2500 m) has been extensively studied over the last few years, but few functional adaptive genetic variants have been identified, largely owing to the lack of deep-genome sequencing data available to previous studies. …”
Publicado 2019
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16por Liang, Tian, Liu, Fang, Ma, Lifeng, Zhang, Zhiying, Liu, Lijun, Huang, Tingting, Li, Jing, Dong, Wenxue, Zhang, Han, Li, Yansong, Jiang, Yaqiong, Ye, Weimin, Bai, Su, Kang, Longli“…Located in southwestern China, Tibet has an average altitude of 4,000 meters and is known as the world’s roof. …”
Publicado 2021
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17por Rong, Hao, He, Xue, Zhu, Linhao, Zhu, Xikai, Kang, Longli, Wang, Li, He, Yongjun, Yuan, Dongya, Jin, Tianbo“…High altitude pulmonary edema (HAPE) is a paradigm of pulmonary edema. …”
Publicado 2017
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