“…Extended Spectrum Beta-Lactamase (ESBL) genes such as blaCTX-M, blaOXA, and blaTEM were abundant, though subtle difference in the prevalence of AMR genes between two cities was observed (Figure 2). [Figure: see text] [Figure: see text] [Figure: see text] CONCLUSION: Most of the E. coli isolates contained various ESBL genes and their gyrA genes were mutated to quinolone resistant forms. …”
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“…RESULTS: Of 1,778 patients with ASB, 74.7% (N = 1328) had a Ucx ordered by an EM clinician (Figure 1), and 74.4% (N = 1323) were treated with antibiotics (Figure 2). …”
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“…Overall, 43.1% (n=241) of the antibiotics were categorized Access and 54.4% (n=304) Watch [Figure 1]. Cephalosporins were the most common antibiotic class (56% n=313), followed by β-lactam inhibitors (18% n=106) and narrow penicillins (8.2% n=46) [Figure 2]. …”
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“…Interestingly, most of the Acinetobacter isolates that belong to ST2 (ST195 and ST281, Oxford) are CRAb with qacE gene. [Figure: see text] [Figure: see text] [Figure: see text] CONCLUSION: Clinical isolates in our study had an even distribution of both CRAb and CSAb. …”
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“…[Figure: see text] [Figure: see text] [Figure: see text] CONCLUSION: Although there was a trend towards resistance genes affecting outcomes, the full analysis indicated no relationship between resistance genes and overall outcomes. …”
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“…The trend in inappropriate antibiotic use continued to decrease after the intervention by 1.1%/month (P-value = 0.02) (Figure 2a). Of 2493/5151 E-visits specifically for sinus symptoms, guideline-concordant antibiotic use was low (intercept = 8%) pre-intervention (Figure 2b). …”
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“…DSI-CB implementation was associated with significant reductions in rates of total respiratory cultures ordered, rates of positive respiratory cultures & reductions in both total & broad-spectrum ICU-AURs (Table 2, Figure 1). [Figure: see text] [Figure: see text] CONCLUSION: Implementation of a novel VAP DSI-CB was safe, feasible & associated with significant reductions in rates of respiratory culture positivity and ICU-AURs. …”
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“…[Image: see text] Figure 2. Prevalence of ABX resistance genes by hospital. …”
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“…Branch lengths reflect the number of allele differences between the isolates in the connected nodes [Image: see text] Figure 2. Minimum spanning tree (MST) of wgMLST profiles of Klebsiella pneumoniae isolates. …”
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“…On adjusted analysis, there were no differences in patient outcomes (Figure 2). CONCLUSION: Among patients with HCAP started on empiric MRSA and PSA coverage without microbiological diagnosis, clinical outcomes were similar in patients switched to an NS antibiotic and those maintained on BS antibiotics. …”
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“…METHODS: An antibiotic NE algorithm was developed to characterize vancomycin use (Figure) at a large academic institution (1/2016–8/2019). …”
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“…No further NDMKP cases have been identified to date. [Figure: see text] Each line represents a scope, each color represents a patient. …”
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“…After UV treatment ST1193, ST399, and ST7394 were not recovered. [Figure: see text] [Figure: see text] CONCLUSION: During UV intervention 3 different STs (ST1193, ST399, ST7394) were not recovered, but there were negligible changes to the frequency of recovery of the other 6 STs as compared to sham UV treatment. …”
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“…For all phenotypes, there was significant variation in resistance across census regions (all P< 0.001) with the highest in the East South Central region and lowest in the New England region of the US (Table). The figure shows regional prevalence of ESBL+ E. coli in 2019. …”
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“…The data shows that the intervention PX-UV group had a reduction of clonal recovery by 10 STs as compared to the sham UV group. [Figure: see text] [Figure: see text] CONCLUSION: The overall reductions in the number of isolates in the real UV units was driven by reductions in the ST117 a predominant strain in a hospital environment reported previously in Detroit and ST80. …”
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“…The results of a univariate analysis for infection are shown in Figure 1. There were no statistically significant differences in all-cause mortality (40% vs. 17%, P = 0.08) and incidence of heart transplantation (19% vs. 34%, P = 0.09) between those with infection and those without infection; the number of hospital readmissions were more common in patients with infection (median, 4 vs. 2, P < 0.01). …”
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“…In the mortality risk model, the AUROCs for qSOFA, SOFA and SIRS were 0.75, 0.70 and 0.71, respectively (Figure). The AUROC for qSOFA ≥2 was significantly higher than for SIRS ≥2 and SOFA ≥2 (P = 0.004, P < 0.001, respectively). …”
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“…No differences in global clinical cure and other clinical outcomes were seen between groups (Figure 1). On multivariable logistic regression analysis, only relapsed/refractory malignancy was identified as an independent predictor of global clinical failure (odds ratio, OR, 9.43; 95% confidence interval, CI, 1.17–76.9; P = 0.035). …”
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“…All 14 respiratory viruses in the diagnostic panel were positive for at least one HA-RVI (Figure 1), but rhino/enterovirus (99), influenza A (27), human metapneumovirus (22) and respiratory syncytial virus (20) were most common. …”
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“…The addition of SOFA ≥6 to the baseline risk model produced the highest AUROC values in both the BSI and non-BSI cohorts (figure). CONCLUSION: Among immunocompromised patients, an SOFA score ≥6 was the strongest predictor of mortality. …”
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