-
1“…This review summarizes our current knowledge of both the formation and function of the Drosophila melanogaster digestive tract, with a major focus on its main digestive/absorptive portion: the strikingly adaptable adult midgut.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
2“…To elucidate mechanisms underlying the complex relationships between a host and its microbiota, we used the genetically tractable model Drosophila melanogaster. Consistent with previous studies, the microbiota was simple in composition and diversity. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
3por Paredes, Juan C., Herren, Jeremy K., Schüpfer, Fanny, Marin, Ray, Claverol, Stéphane, Kuo, Chih-Horng, Lemaitre, Bruno, Béven, Laure“…Here we provide the first genome sequence, along with proteomic validation, of an endosymbiotic inherited Spiroplasma bacterium, the Spiroplasma poulsonii MSRO strain harbored by Drosophila melanogaster. Comparison of the genome content of S. poulsonii with that of horizontally transmitted spiroplasmas indicates that S. poulsonii has lost many metabolic pathways and transporters, demonstrating a high level of interdependence with its insect host. …”
Publicado 2015
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
4
-
5por Bretscher, Andrew J., Honti, Viktor, Binggeli, Olivier, Burri, Olivier, Poidevin, Mickael, Kurucz, Éva, Zsámboki, János, Andó, István, Lemaitre, BrunoEnlace del recurso
Publicado 2015
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
6“…In the fruit fly Drosophila melanogaster, the iron transporter Transferrin 1 (Tsf1) mediates iron relocation from the hemolymph to the fat body upon infection as part of the nutritional immune response. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
7por Melcarne, Claudia, Ramond, Elodie, Dudzic, Jan, Bretscher, Andrew J., Kurucz, Éva, Andó, István, Lemaitre, BrunoEnlace del recurso
Publicado 2019
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
8por Ramond, Elodie, Maclachlan, Catherine, Clerc-Rosset, Stéphanie, Knott, Graham W., Lemaitre, Bruno“…This clade includes many vertically transmitted insect endosymbionts, including Spiroplasma poulsonii, a natural endosymbiont of Drosophila melanogaster. S. poulsonii bacteria are mainly found in the hemolymph of infected female flies and exhibit efficient vertical transmission from mother to offspring. …”
Publicado 2016
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
9por Herren, Jeremy K, Paredes, Juan C, Schüpfer, Fanny, Arafah, Karim, Bulet, Philippe, Lemaitre, Bruno“…Spiroplasma poulsonii is a maternally transmitted bacterial endosymbiont that is naturally associated with Drosophila melanogaster. S. poulsonii resides extracellularly in the hemolymph, where it must acquire metabolites to sustain proliferation. …”
Publicado 2014
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
10Male-killing symbiont damages host's dosage-compensated sex chromosome to induce embryonic apoptosis“…Here, we uncover the molecular and cellular mechanisms underlying Spiroplasma-induced embryonic male lethality in Drosophila melanogaster. Transcriptomic analysis reveals that many genes related to DNA damage and apoptosis are up-regulated specifically in infected male embryos. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
11por Masson, Florent, Calderon‐Copete, Sandra, Schüpfer, Fanny, Vigneron, Aurélien, Rommelaere, Samuel, Garcia‐Arraez, Mario G., Paredes, Juan C., Lemaitre, Bruno“…Spiroplasma poulsonii is a vertically transmitted endosymbiont of Drosophila melanogaster that causes male‐killing, that is the death of infected male embryos during embryogenesis. …”
Publicado 2020
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
12“…Drosophila melanogaster’s blood cells (hemocytes) play essential roles in wound healing and are involved in clearing microbial infections. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
13“…Spiroplasma is a diverse bacterial clade that includes many vertically transmitted insect endosymbionts, including Spiroplasma poulsonii, a natural endosymbiont of Drosophila melanogaster. These bacteria persist in the hemolymph of their adult host and exhibit efficient vertical transmission from mother to offspring. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
14por Hanson, Mark Austin, Cohen, Lianne B., Marra, Alice, Iatsenko, Igor, Wasserman, Steven A., Lemaitre, Bruno“…The fruit fly Drosophila melanogaster combats microbial infection by producing a battery of effector peptides that are secreted into the haemolymph. …”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
15por Hamilton, Phineas T., Votýpka, Jan, Dostálová, Anna, Yurchenko, Vyacheslav, Bird, Nathan H., Lukeš, Julius, Lemaitre, Bruno, Perlman, Steve J.“…Despite the importance of Drosophila melanogaster as a model of infection and immunity and a long awareness that trypanosomatid infection is common in the genus, no trypanosomatid parasites naturally infecting Drosophila have been characterized. …”
Publicado 2015
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
16“…Here, we analyze the mechanisms underlying protection from parasitoid wasps in Drosophila melanogaster mediated by its facultative endosymbiont Spiroplasma poulsonii. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
17“…During our immune study characterizing the antimicrobial peptide gene Baramicin, we recovered multiple Baramicin paralogs in Drosophila melanogaster and other species, united by their N-terminal IM24 domain. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
18por Masson, Florent, Rommelaere, Samuel, Schüpfer, Fanny, Boquete, Jean-Philippe, Lemaitre, Bruno“…Here, we investigate the nutritional interactions between endosymbiotic partners using the tractable insect Drosophila melanogaster and its natural endosymbiont Spiroplasma poulsonii. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
19por Fabian, Daniel K., Garschall, Kathrin, Klepsatel, Peter, Santos‐Matos, Gonçalo, Sucena, Élio, Kapun, Martin, Lemaitre, Bruno, Schlötterer, Christian, Arking, Robert, Flatt, Thomas“…Here, we have analyzed the genomes of a set of Drosophila melanogaster lines that have been maintained under direct selection for postponed reproduction and indirect selection for longevity, relative to unselected control lines, for over 35 years. …”
Publicado 2018
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
20por Garcia-Arraez, Mario Gonzalo, Masson, Florent, Escobar, Juan Camilo Paredes, Lemaitre, Bruno“…One example is the association between the vertically transmitted facultative endosymbiont Spiroplasma poulsonii and its natural host Drosophila melanogaster. Whereas S. poulsonii protects its host against parasitoid wasps and nematodes by the action of toxins from the family of Ribosome Inactivating Proteins (RIPs), the presence of S. poulsonii has been reported to reduce host’s life span and to kill male embryos by a toxin called Spaid. …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto