Mostrando 1 - 19 Resultados de 19 Para Buscar '"The Messengers"', tiempo de consulta: 0.90s Limitar resultados
  1. 1
    por Sart, Sébastien, Song, Liqing, Li, Yan
    Publicado 2015
    “…However, recent findings have challenged this dogma and physiological levels of ROS are now considered as secondary messengers, mediating numerous cellular functions in stem cells. …”
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    Controlling Redox Status for Stem Cell Survival, Expansion, and Differentiation
  2. 2
    “…TIPE3 (TNFAIP8L3) is the transfer protein of phosphoinositide second messengers that promote cancer. Its role in breast cancer has not been evaluated. …”
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    TIPE3 protein promotes breast cancer metastasis through activating AKT and NF-κB signaling pathways
  3. 3
    “…Circulating exosomal miRNAs may play an important role in metabolic dysfunction in NS workers by serving as messengers of circadian misalignment to peripheral tissues.…”
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    Circulating Exosomal miRNAs Signal Circadian Misalignment to Peripheral Metabolic Tissues
  4. 4
    “…HSP70/HSP70-PCs treatment did not alter the messenger RNA (mRNA) or protein levels of matrix metalloproteinase-9; the opposite was true for Ras homolog family member A (RhoA) mRNA and protein levels. …”
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    Extracellular HSP70/HSP70-PCs regulate hepatocarcinoma cell migration and invasion via RhoA
  5. 5
    “…In exoRBase 2.0, the number of exLRs has increased to 19 643 messenger RNAs (mRNAs), 15 645 long non-coding RNAs (lncRNAs) and 79 084 circular RNAs (circRNAs) obtained from ∼1000 human blood, urine, cerebrospinal fluid (CSF) and bile samples. …”
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    exoRBase 2.0: an atlas of mRNA, lncRNA and circRNA in extracellular vesicles from human biofluids
  6. 6
    “…Here, we develop a web-accessible database (http://www.exoRBase.org), exoRBase, which is a repository of circular RNA (circRNA), long non-coding RNA (lncRNA) and messenger RNA (mRNA) derived from RNA-seq data analyses of human blood exosomes. …”
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    exoRBase: a database of circRNA, lncRNA and mRNA in human blood exosomes
  7. 7
    “…METHODS: Quantitative real-time polymerase chain (qRT-PCR) was applied to determine HSP70 messenger RNA (mRNA) levels, and immunohistochemistry assay was conducted to determine HSP70 protein level. …”
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    The HSP70 gene predicts prognosis and response to chemotherapy in epithelial ovarian cancer
  8. 8
    “…These results indicate that Dcp2 plays a critical role in the response to chronic nicotine exposure. Moreover, the messenger RNA (mRNA) level of Dcp2 in the fly head was suppressed by chronic nicotine treatment, and up-regulation of Dcp2 expression in the nervous system blocked cNILH. …”
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    Down-Regulation of Decapping Protein 2 Mediates Chronic Nicotine Exposure-Induced Locomotor Hyperactivity in Drosophila
  9. 9
    “…The gene features contain network topology information, because it is extracted by integrating deoxyribonucleic acid methylation, messenger ribonucleic acid expression data, and protein–protein interactions through network embedding method. …”
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    NESM: a network embedding method for tumor stratification by integrating multi-omics data
  10. 10
    “…On the other hand, CX-5461 increased p53 accumulation and messenger RNA level of its target genes, p21, MDM2, and Sestrin1/2 in U2-OS cells. …”
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    CX-5461 induces autophagy and inhibits tumor growth via mammalian target of rapamycin-related signaling pathways in osteosarcoma
  11. 11
    “…METHODS: Cell growth inhibition was determined by methyl thiazolyl tetrazolium assay; cell morphology and apoptosis were observed under transmission electron microscope; cell cycle and apoptosis rates were detected using flow cytometry; B‐cell lymphoma 2 (Bcl‐2) and Bcl‐2‐like protein 4 (Bax) messenger RNA expression were determined by quantitative PCR; and p53, p73, p53 upregulated modulator of apoptosis (PUMA), Bax, Bcl‐2, and caspase‐9 protein expression were detected by Western blotting. …”
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    Sulforaphane‐induced apoptosis in Xuanwei lung adenocarcinoma cell line XWLC‐05
  12. 12
    “…Cyclic diguanylate (c-di-GMP) is a nearly universal second messenger in bacteria and modulates various important physiological processes, including motility, biofilm formation, antifungal antibiotic production and host colonization. …”
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    Cyclic di-GMP regulates bacterial colonization and further biocontrol efficacy of Bacillus velezensis against apple ring rot disease via its potential receptor YdaK
  13. 13
    “…Further functional effects were tested by small interfering RNA knockdown of the gene for interferon regulatory factor 5 (IRF5), followed by reverse transcription–qPCR (RT‐qPCR) and enzyme‐linked immunosorbent assay (ELISA) to measure the levels of IFNγ messenger RNA (mRNA) and protein, respectively. RESULTS: In nuclear extracts from CD8+ T cells, results of qMS showed that relative TF binding to the AS‐risk A allele of rs4648889 was increased 3.7‐fold (P < 0.03) for Ikaros family zinc‐finger protein 3 (IKZF3; Aiolos) and components of the NuRD complex, including chromodomain helicase DNA binding protein 4 (CHD4) (3.6‐fold increase; P < 0.05) and retinoblastoma binding protein 4 (RBBP4) (4.1‐fold increase; P < 0.03). …”
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    Functional Genomic Analysis of a RUNX3 Polymorphism Associated With Ankylosing Spondylitis
  14. 14
    por Thompson, Mark G., Burgess, Jefferey L., Naleway, Allison L., Tyner, Harmony, Yoon, Sarang K., Meece, Jennifer, Olsho, Lauren E.W., Caban-Martinez, Alberto J., Fowlkes, Ashley L., Lutrick, Karen, Groom, Holly C., Dunnigan, Kayan, Odean, Marilyn J., Hegmann, Kurt, Stefanski, Elisha, Edwards, Laura J., Schaefer-Solle, Natasha, Grant, Lauren, Ellingson, Katherine, Kuntz, Jennifer L., Zunie, Tnelda, Thiese, Matthew S., Ivacic, Lynn, Wesley, Meredith G., Mayo Lamberte, Julie, Sun, Xiaoxiao, Smith, Michael E., Phillips, Andrew L., Groover, Kimberly D., Yoo, Young M., Gerald, Joseph, Brown, Rachel T., Herring, Meghan K., Joseph, Gregory, Beitel, Shawn, Morrill, Tyler C., Mak, Josephine, Rivers, Patrick, Poe, Brandon P., Lynch, Brian, Zhou, Yingtao, Zhang, Jing, Kelleher, Anna, Li, Yan, Dickerson, Monica, Hanson, Erika, Guenther, Kyley, Tong, Suxiang, Bateman, Allen, Reisdorf, Erik, Barnes, John, Azziz-Baumgartner, Eduardo, Hunt, Danielle R., Arvay, Melissa L., Kutty, Preeta, Fry, Alicia M., Gaglani, Manjusha
    Publicado 2021
    “…BACKGROUND: Information is limited regarding the effectiveness of the two-dose messenger RNA (mRNA) vaccines BNT162b2 (Pfizer–BioNTech) and mRNA-1273 (Moderna) in preventing infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and in attenuating coronavirus disease 2019 (Covid-19) when administered in real-world conditions. …”
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    Prevention and Attenuation of Covid-19 with the BNT162b2 and mRNA-1273 Vaccines
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    “…Activated AMPK upregulated the messenger RNA expression and protein levels of atrogin-1, a muscle-specific ubiquitin ligase, in the myocardium. …”
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    Metformin-Enhanced Cardiac AMP-Activated Protein Kinase/Atrogin-1 Pathways Inhibit Charged Multivesicular Body Protein 2B Accumulation in Ischemia–Reperfusion Injury
  16. 16
    “…We further demonstrated that miR-320a-3p could regulate fibrosis by targeting FOXM1 messenger RNA (mRNA) 3′-untranslated region (UTR). …”
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    ALKBH5 promotes lung fibroblast activation and silica-induced pulmonary fibrosis through miR-320a-3p and FOXM1
  17. 17
    “…Compared with D1 and T2 group, the T3 group showed an expression of messenger ribonucleic acid (mRNA) that is associated with (CPS-1, ASS1, OTC, ARG) and (N-AGS, S6K1, eIF4B, mTORC1) in liver; moreover, the T3 group was significantly enhanced (p < 0.05). …”
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    Rumen-Protected Lysine and Methionine Supplementation Reduced Protein Requirement of Holstein Bulls by Altering Nitrogen Metabolism in Liver
  18. 18
    “…The present study aimed to investigate the effects of 17β-estradiol and tamoxifen, an agonist and inhibitor of the estrogen receptor (ER), respectively, on the proliferation and apoptosis of gastric cancer cells, as well as the messenger (m)RNA expression levels of ER-α36. Nested reverse transcription-polymerase chain reaction (RT-PCR) confirmed that ER-α36 was expressed in the BGC823, MKN45 and SGC7901 human gastric cancer cell lines. …”
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    Effects of 17β-estradiol and tamoxifen on gastric cancer cell proliferation and apoptosis and ER-α36 expression
  19. 19
    por Zhou, Lin-Yan, Xie, Ying, Li, Yan
    Publicado 2022
    “…After blocking PD-L1, the messenger ribonucleic acid and protein expression of PD-1 were invariant. …”
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    Bifidobacterium infantis regulates the programmed cell death 1 pathway and immune response in mice with inflammatory bowel disease
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