GWAS-Identified Variants for Obesity Do Not Influence the Risk of Developing Multiple Myeloma: A Population-Based Study and Meta-Analysis

Por Sánchez-Maldonado, José Manuel, Cabrera-Serrano, Antonio José, Chattopadhyay, Subhayan, Campa, Daniele, Garrido, María del Pilar, Macauda, Angelica, Ter Horst, Rob, Jerez, Andrés, Netea, Mihai G., Li, Yang, Hemminki, Kari, Canzian, Federico, Försti, Asta, Sainz, Juan
Publicado em 2023

Differences in Immune Responses in Individuals of Indian and European Origin: Relevance for the COVID-19 Pandemic

Por Geckin, Büsra, Zoodsma, Martijn, Kilic, Gizem, Debisarun, Priya A., Rakshit, Srabanti, Adiga, Vasista, Ahmed, Asma, Parthiban, Chaitra, Kumar, Nirutha Chetan, D’Souza, George, Baltissen, Marijke P., Martens, Joost H. A., Domínguez-Andrés, Jorge, Li, Yang, Vyakarnam, Annapurna, Netea, Mihai G.
Publicado em 2023

Do GWAS-Identified Risk Variants for Chronic Lymphocytic Leukemia Influence Overall Patient Survival and Disease Progression?

Por Cabrera-Serrano, Antonio José, Sánchez-Maldonado, José Manuel, ter Horst, Rob, Macauda, Angelica, García-Martín, Paloma, Benavente, Yolanda, Landi, Stefano, Clay-Gilmour, Alyssa, Niazi, Yasmeen, Espinet, Blanca, Rodríguez-Sevilla, Juan José, Pérez, Eva María, Maffei, Rossana, Blanco, Gonzalo, Giaccherini, Matteo, Cerhan, James R., Marasca, Roberto, López-Nevot, Miguel Ángel, Chen-Liang, Tzu, Thomsen, Hauke, Gámez, Irene, Campa, Daniele, Moreno, Víctor, de Sanjosé, Silvia, Marcos-Gragera, Rafael, García-Álvarez, María, Dierssen-Sotos, Trinidad, Jerez, Andrés, Butrym, Aleksandra, Norman, Aaron D., Luppi, Mario, Slager, Susan L., Hemminki, Kari, Li, Yang, Berndt, Sonja I., Casabonne, Delphine, Alcoceba, Miguel, Puiggros, Anna, Netea, Mihai G., Försti, Asta, Canzian, Federico, Sainz, Juan
Publicado em 2023

Polymorphisms within Autophagy-Related Genes as Susceptibility Biomarkers for Multiple Myeloma: A Meta-Analysis of Three Large Cohorts and Functional Characterization

Por Clavero, Esther, Sanchez-Maldonado, José Manuel, Macauda, Angelica, Ter Horst, Rob, Sampaio-Marques, Belém, Jurczyszyn, Artur, Clay-Gilmour, Alyssa, Stein, Angelika, Hildebrandt, Michelle A. T., Weinhold, Niels, Buda, Gabriele, García-Sanz, Ramón, Tomczak, Waldemar, Vogel, Ulla, Jerez, Andrés, Zawirska, Daria, Wątek, Marzena, Hofmann, Jonathan N., Landi, Stefano, Spinelli, John J., Butrym, Aleksandra, Kumar, Abhishek, Martínez-López, Joaquín, Galimberti, Sara, Sarasquete, María Eugenia, Subocz, Edyta, Iskierka-Jażdżewska, Elzbieta, Giles, Graham G., Rybicka-Ramos, Malwina, Kruszewski, Marcin, Abildgaard, Niels, Verdejo, Francisco García, Sánchez Rovira, Pedro, da Silva Filho, Miguel Inacio, Kadar, Katalin, Razny, Małgorzata, Cozen, Wendy, Pelosini, Matteo, Jurado, Manuel, Bhatti, Parveen, Dudzinski, Marek, Druzd-Sitek, Agnieszka, Orciuolo, Enrico, Li, Yang, Norman, Aaron D., Zaucha, Jan Maciej, Reis, Rui Manuel, Markiewicz, Miroslaw, Rodríguez Sevilla, Juan José, Andersen, Vibeke, Jamroziak, Krzysztof, Hemminki, Kari, Berndt, Sonja I., Rajkumar, Vicent, Mazur, Grzegorz, Kumar, Shaji K., Ludovico, Paula, Nagler, Arnon, Chanock, Stephen J., Dumontet, Charles, Machiela, Mitchell J., Varkonyi, Judit, Camp, Nicola J., Ziv, Elad, Vangsted, Annette Juul, Brown, Elizabeth E., Campa, Daniele, Vachon, Celine M., Netea, Mihai G., Canzian, Federico, Försti, Asta, Sainz, Juan
Publicado em 2023

A single-cell view on host immune transcriptional response to in vivo BCG-induced trained immunity

Por Li, Wenchao, Moorlag, Simone J.C.F.M., Koeken, Valerie A.C.M., Röring, Rutger J., de Bree, L. Charlotte J., Mourits, Vera P., Gupta, Manoj K., Zhang, Bowen, Fu, Jianbo, Zhang, Zhenhua, Grondman, Inge, van Meijgaarden, Krista E., Zhou, Liang, Alaswad, Ahmed, Joosten, Leo A.B., van Crevel, Reinout, Xu, Cheng-Jian, Netea, Mihai G., Li, Yang
Publicado em 2023

Peripheral blood mononuclear cell hyperresponsiveness in patients with premature myocardial infarction without traditional risk factors

Por Mol, Jan-Quinten, van Tuijl, Julia, Bekkering, Siroon, van der Heijden, Charlotte D.C.C., Damen, Sander A.J., Cossins, Benjamin C., van Emst, Liesbeth, Nielen, Tim M., Rodwell, Laura, Li, Yang, Pop, Gheorghe A.M., Netea, Mihai G., van Royen, Niels, Riksen, Niels P., El Messaoudi, Saloua
Publicado em 2023

Identification of novel genetic loci for risk of multiple myeloma by functional annotation

Por Macauda, Angelica, Briem, Klara, Clay-Gilmour, Alyssa, Cozen, Wendy, Försti, Asta, Giaccherini, Matteo, Corradi, Chiara, Sainz, Juan, Niazi, Yasmeen, ter Horst, Rob, Li, Yang, Netea, Mihai G., Vogel, Ulla, Hemminki, Kari, Slager, Susan L., Varkonyi, Judit, Andersen, Vibeke, Iskierka-Jazdzewska, Elzbieta, Mártinez-Lopez, Joaquin, Zaucha, Jan, Camp, Nicola J., Rajkumar, S. Vincent, Druzd-Sitek, Agnieszka, Bhatti, Parveen, Chanock, Stephen J., Kumar, Shaji K., Subocz, Edyta, Mazur, Grzegorz, Landi, Stefano, Machiela, Mitchell J., Jerez, Andrés, Norman, Aaron D., Hildebrandt, Michelle A. T., Kadar, Katalin, Berndt, Sonja I., Ziv, Elad, Buda, Gabriele, Nagler, Arnon, Dumontet, Charles, Raźny, Malgorzata, Watek, Marzena, Butrym, Aleksandra, Grzasko, Norbert, Dudzinski, Marek, Rybicka-Ramos, Malwina, Matera, Eva-Laure, García-Sanz, Ramón, Goldschmidt, Hartmut, Jamroziak, Krzysztof, Jurczyszyn, Artur, Clavero, Esther, Giles, Graham G., Pelosini, Matteo, Zawirska, Daria, Kruszewski, Marcin, Marques, Herlander, Haastrup, Eva, Sánchez-Maldonado, José Manuel, Bertsch, Uta, Rymko, Marcin, Raab, Marc-Steffen, Brown, Elizabeth E., Hofmann, Jonathan N., Vachon, Celine, Campa, Daniele, Canzian, Federico
Publicado em 2023

Refined mapping of autoimmune disease associated genetic variants with gene expression suggests an important role for non-coding RNAs

Por Ricaño-Ponce, Isis, Zhernakova, Daria V., Deelen, Patrick, Luo, Oscar, Li, Xingwang, Isaacs, Aaron, Karjalainen, Juha, Di Tommaso, Jennifer, Borek, Zuzanna Agnieszka, Zorro, Maria M., Gutierrez-Achury, Javier, Uitterlinden, Andre G., Hofman, Albert, van Meurs, Joyce, Netea, Mihai G., Jonkers, Iris H., Withoff, Sebo, van Duijn, Cornelia M., Li, Yang, Ruan, Yijun, Franke, Lude, Wijmenga, Cisca, Kumar, Vinod
Publicado em 2016

An integrative genomics approach identifies novel pathways that influence candidaemia susceptibility

Por Matzaraki, Vasiliki, Gresnigt, Mark S., Jaeger, Martin, Ricaño-Ponce, Isis, Johnson, Melissa D., Oosting, Marije, Franke, Lude, Withoff, Sebo, Perfect, John R., Joosten, Leo A. B., Kullberg, Bart Jan, van de Veerdonk, Frank L., Jonkers, Iris, Li, Yang, Wijmenga, Cisca, Netea, Mihai G., Kumar, Vinod
Publicado em 2017

Identification of Discriminating Metabolic Pathways and Metabolites in Human PBMCs Stimulated by Various Pathogenic Agents

Por Zhang, Xiang, Mardinoglu, Adil, Joosten, Leo A. B., Kuivenhoven, Jan A., Li, Yang, Netea, Mihai G., Groen, Albert K.
Publicado em 2018

Integration of multi-omics data and deep phenotyping enables prediction of cytokine responses

Por Bakker, Olivier B., Aguirre-Gamboa, Raul, Sanna, Serena, Oosting, Marije, Smeekens, Sanne P., Jaeger, Martin, Zorro, Maria, Võsa, Urmo, Withoff, Sebo, Netea-Maier, Romana T., Koenen, Hans J.P.M., Joosten, Irma, Xavier, Ramnik J., Franke, Lude, Joosten, Leo A.B., Kumar, Vinod, Wijmenga, Cisca, Netea, Mihai G., Li, Yang
Publicado em 2018

Steroid hormone-related polymorphisms associate with the development of bone erosions in rheumatoid arthritis and help to predict disease progression: Results from the REPAIR conso...

Por Sánchez-Maldonado, Jose M., Cáliz, Rafael, Canet, Luz, Horst, Rob ter, Bakker, Olivier, den Broeder, Alfons A., Martínez-Bueno, Manuel, Canhão, Helena, Rodríguez-Ramos, Ana, Lupiañez, Carmen B., Soto-Pino, María José, García, Antonio, Pérez-Pampin, Eva, González-Utrilla, Alfonso, Escudero, Alejandro, Segura-Catena, Juana, Netea-Maier, Romana T., Ferrer, Miguel Ángel, Collantes-Estevez, Eduardo, López Nevot, Miguel Ángel, Li, Yang, Jurado, Manuel, Fonseca, João E., Netea, Mihai G., Coenen, Marieke J. H., Sainz, Juan
Publicado em 2019

Leukocyte-Released Mediators in Response to Both Bacterial and Fungal Infections Trigger IFN Pathways, Independent of IL-1 and TNF-α, in Endothelial Cells

Por Le, Kieu T. T., Chu, Xiaojing, Jaeger, Martin, Plantinga, Josée A., Matzaraki, Vasiliki, Withoff, Sebo, Joosten, Leo A. B., Netea, Mihai G., Wijmenga, Cisca, Li, Yang, Moser, Jill, Kumar, Vinod
Publicado em 2019

NFKB2 polymorphisms associate with the risk of developing rheumatoid arthritis and response to TNF inhibitors: Results from the REPAIR consortium

Por Manuel Sánchez-Maldonado, Jose, Martínez-Bueno, Manuel, Canhão, Helena, ter Horst, Rob, Muñoz-Peña, Sonia, Moñiz-Díez, Ana, Rodríguez-Ramos, Ana, Escudero, Alejandro, Sorensen, Signe B., Hetland, Merete L., Ferrer, Miguel A., Glintborg, Bente, Filipescu, Ileana, Pérez-Pampin, Eva, Conesa-Zamora, Pablo, García, Antonio, den Broeder, Alfons, De Vita, Salvatore, Hove Jacobsen, Svend Erik, Collantes, Eduardo, Quartuccio, Luca, Netea, Mihai G., Li, Yang, Fonseca, João E., Jurado, Manuel, López-Nevot, Miguel Ángel, Coenen, Marieke J. H., Andersen, Vibeke, Cáliz, Rafael, Sainz, Juan
Publicado em 2020

The Set7 Lysine Methyltransferase Regulates Plasticity in Oxidative Phosphorylation Necessary for Trained Immunity Induced by β-Glucan

Por Keating, Samuel T., Groh, Laszlo, van der Heijden, Charlotte D.C.C., Rodriguez, Hanah, dos Santos, Jéssica C., Fanucchi, Stephanie, Okabe, Jun, Kaipananickal, Harikrishnan, van Puffelen, Jelmer H., Helder, Leonie, Noz, Marlies P., Matzaraki, Vasiliki, Li, Yang, de Bree, L. Charlotte J., Koeken, Valerie A.C.M., Moorlag, Simone J.C.F.M., Mourits, Vera P., Domínguez-Andrés, Jorge, Oosting, Marije, Bulthuis, Elianne P., Koopman, Werner J.H., Mhlanga, Musa, El-Osta, Assam, Joosten, Leo A.B., Netea, Mihai G., Riksen, Niels P.
Publicado em 2020

Deconvolution of bulk blood eQTL effects into immune cell subpopulations

Por Aguirre-Gamboa, Raúl, de Klein, Niek, di Tommaso, Jennifer, Claringbould, Annique, van der Wijst, Monique GP, de Vries, Dylan, Brugge, Harm, Oelen, Roy, Võsa, Urmo, Zorro, Maria M., Chu, Xiaojin, Bakker, Olivier B., Borek, Zuzanna, Ricaño-Ponce, Isis, Deelen, Patrick, Xu, Cheng-Jiang, Swertz, Morris, Jonkers, Iris, Withoff, Sebo, Joosten, Irma, Sanna, Serena, Kumar, Vinod, Koenen, Hans J. P. M., Joosten, Leo A. B., Netea, Mihai G., Wijmenga, Cisca, Franke, Lude, Li, Yang
Publicado em 2020

BCG Vaccination in Humans Elicits Trained Immunity via the Hematopoietic Progenitor Compartment

Por Cirovic, Branko, de Bree, L. Charlotte J., Groh, Laszlo, Blok, Bas A., Chan, Joyce, van der Velden, Walter J.F.M., Bremmers, M.E.J., van Crevel, Reinout, Händler, Kristian, Picelli, Simone, Schulte-Schrepping, Jonas, Klee, Kathrin, Oosting, Marije, Koeken, Valerie A.C.M., van Ingen, Jakko, Li, Yang, Benn, Christine S., Schultze, Joachim L., Joosten, Leo A.B., Curtis, Nigel, Netea, Mihai G., Schlitzer, Andreas
Publicado em 2020

Rewiring of glucose metabolism defines trained immunity induced by oxidized low-density lipoprotein

Por Keating, Samuel T., Groh, Laszlo, Thiem, Kathrin, Bekkering, Siroon, Li, Yang, Matzaraki, Vasiliki, van der Heijden, Charlotte D. C. C., van Puffelen, Jelmer H., Lachmandas, Ekta, Jansen, Trees, Oosting, Marije, de Bree, L. Charlotte J., Koeken, Valerie A. C. M., Moorlag, Simone J. C. F. M., Mourits, Vera P., van Diepen, Janna, Strienstra, Rinke, Novakovic, Boris, Stunnenberg, Hendrik G., van Crevel, Reinout, Joosten, Leo A. B., Netea, Mihai G., Riksen, Niels P.
Publicado em 2020

Sex-Specific Regulation of Inflammation and Metabolic Syndrome in Obesity

Por ter Horst, Rob, van den Munckhof, Inge C.L., Schraa, Kiki, Aguirre-Gamboa, Raul, Jaeger, Martin, Smeekens, Sanne P., Brand, Tessa, Lemmers, Heidi, Dijkstra, Helga, Galesloot, Tessel E., de Graaf, Jacqueline, Xavier, Ramnik J., Li, Yang, Joosten, Leo A.B., Rutten, Joost H.W., Netea, Mihai G., Riksen, Niels P.
Publicado em 2020

Multi-omics examination of Q fever fatigue syndrome identifies similarities with chronic fatigue syndrome

Por Raijmakers, Ruud P. H., Roerink, Megan E., Jansen, Anne F. M., Keijmel, Stephan P., Gacesa, Ranko, Li, Yang, Joosten, Leo A. B., van der Meer, Jos W. M., Netea, Mihai G., Bleeker-Rovers, Chantal P., Xu, Cheng-Jian
Publicado em 2020