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1por Ye, Qiang, Li, Zi, Li, Yang, Li, Yirong, Zhang, Yan, Gui, Runlin, Cui, Yue, Zhang, Qi, Qian, Lu, Xiong, Yuyan, Yu, Yi“…Recently, exosomes as essential intercellular messengers are receiving great interest for their important roles in melanoma progression, diagnosis, and treatment. …”
Publicado 2022
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2“…In recent years, an increasing number of studies have focused on the neurobiological effects of EMR, including the metabolism and transport of neurotransmitters. As messengers of synaptic transmission, neurotransmitters play critical roles in cognitive and emotional behavior. …”
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3“…Reactive oxygen species (ROS), previously considered intracellular byproducts of aerobic metabolism, are now known to regulate multiple signaling pathways as second messengers. Cancer cells cope with elevated amounts of ROS during therapy by upregulating the antioxidant system, enabling tumor therapeutic resistance via a variety of mechanisms. …”
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4por Li, Suting, Lu, Danhua, Tang, Jianming, Min, Jie, Hu, Ming, Li, Yang, Liu, Yaodan, Wang, Linlin, Liu, Cheng, Hong, Li“…Ca(2+) is an important ion in response to electrical stimulation (ES) and acts as second messenger in the regulation of various physiological processes. …”
Publicado 2019
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5por Chen, Ke, Li, Yang, Xu, Luwei, Qian, Yiguan, Liu, Ning, Zhou, Changcheng, Liu, Jingyu, Zhou, Liuhua, Xu, Zheng, Jia, Ruipeng, Ge, Yu-Zheng“…Extracellular vesicles (EVs) contain many effective components, such as cellular proteins, microRNAs, messenger RNAs, and long noncoding RNAs, and can be secreted by different cell types. …”
Publicado 2022
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6“…Additional strategies, such as a booster vaccination with messenger RNA COVID-19 vaccines, might improve seroprotection for these patients.…”
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7por Deng, Dawei, Li, Yang, Xue, Jianpeng, Wang, Jie, Ai, Guanhua, Li, Xin, Gu, Yueqing“…Messenger RNA (mRNA), a single-strand ribonucleic acid with functional gene information is usually abnormally expressed in cancer cells and has become a promising biomarker for the study of tumor progress. …”
Publicado 2015
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8por Guo, Zhenru, Chen, Qing, Zhu, Jing, Wang, Yan, Li, Yang, Li, Qingcheng, Zhao, Kan, Li, Yue, Tang, Rui, Shi, Xiaoli, Tan, Kenan, Kong, Li, Jiang, Yunfeng, Jiang, Qiantao, Wang, Jirui, Chen, Guoyue, Wei, Yuming, Zheng, Youliang, Qi, Pengfei“…This missense mutation led to a more compact messenger RNA (mRNA) secondary structure around the miRNA172-binding region, resulting in increased Q(c5) expression during the spike development stage and a consequent increase in spike density. …”
Publicado 2022
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9por Li, Jinjie, Li, Yang, Yin, Zhigang, Jiang, Jihong, Zhang, Minghui, Guo, Xiao, Ye, Zhujia, Zhao, Yan, Xiong, Haiyan, Zhang, Zhanying, Shao, Yujie, Jiang, Conghui, Zhang, Hongliang, An, Gynheung, Paek, Nam‐Chon, Ali, Jauhar, Li, Zichao“…The production of H(2)O(2), a second messenger for the induction of stomatal closure in response to ABA, was activated in overexpression plants under drought stress conditions, consequently, increased stomatal closure and decreased stomatal conductance. …”
Publicado 2016
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10por Erstad, Derek J., Farrar, Christian T., Ghoshal, Sarani, Masia, Ricard, Ferreira, Diego S., Chen, Yin‐Ching Iris, Choi, Ji‐Kyung, Wei, Lan, Waghorn, Phillip A., Rotile, Nicholas J., Tu, Chuantao, Graham‐O'Regan, Katherine A., Sojoodi, Mozhdeh, Li, Shen, Li, Yang, Wang, Guogiang, Corey, Kathleen E., Or, Yat Sun, Jiang, Lijuan, Tanabe, Kenneth K., Caravan, Peter, Fuchs, Bryan C.“…Liver tissue was subjected to pathologic and morphometric scoring of fibrosis, hydroxyproline quantitation, and determination of fibrogenic messenger RNA expression. High‐dose EDP‐305 (30 mg/kg) reduced liver fibrosis in both the BDL and CDAHFD models as measured by collagen proportional area, hydroxyproline analysis, and fibrogenic gene expression (all P < 0.05). …”
Publicado 2018
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11“…RESULTS: BRE expression in A549 cells, derived from human lung cells, was markedly decreased compared with parental cisplatin‐resistant A549/DDP cells at messenger ribonucleic acid and protein levels. BRE overexpression in A549 significantly decreased sensitivity to DDP by inhibiting cell apoptosis. …”
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12por Li, Yang, Li, Guoqing, Wang, Fu, Wu, Xiaoshan, Wu, Zhifang, Wang, Jinsong, Zhang, Chunmei, He, Junqi, Wang, Hao, Wang, Songlin“…Here, we performed long noncoding RNA (lncRNA) and messenger RNA (mRNA) expression profiles in the ECM components of deciduous tooth germs by RNA sequencing in miniature pigs. …”
Publicado 2019
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13por Logeswaran, Dhenugen, Li, Yang, Akhter, Khadiza, Podlevsky, Joshua D., Olson, Tamara L., Forsberg, Katherine, Chen, Julian J.-L.“…Here, we report an unprecedented messenger RNA (mRNA)-derived biogenesis pathway for the 1,291 nucleotide TER from the basidiomycete fungus Ustilago maydis. …”
Publicado 2022
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14por Chen, Xing, Ma, Xiang-ming, Yang, Chong-Wu, Jiang, Shu-zhen, Huang, Li-bo, Li, Yang, Zhang, Fan, Jiao, Ning, Yang, Wei-ren“…Histological analysis showed that the addition of organic trace elements could significantly improve the villus height and villus concealment ratio (p < 0.05). In addition, the messenger RNA (mRNA) and protein expressions of divalent metal transporter 1 (DMT1), zinc transporter 1 (ZnT-1), and ferroportin 1 (FPN1) were the highest in the OTE450 group. …”
Publicado 2022
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15por Kramer, Michael H., Zhang, Qiang, Sprung, Robert, Day, Ryan B., Erdmann-Gilmore, Petra, Li, Yang, Xu, Ziheng, Helton, Nichole M., George, Daniel R., Mi, Yiling, Westervelt, Peter, Payton, Jacqueline E., Ramakrishnan, Sai M., Miller, Christopher A., Link, Daniel C., DiPersio, John F., Walter, Matthew J., Townsend, R. Reid, Ley, Timothy J.“…For example, samples with IDH1/2 mutations displayed elevated levels of the 2-oxoglutarate–dependent histone demethylases KDM4A/B/C, despite no changes in messenger RNA levels for these genes; we confirmed this finding in vitro. …”
Publicado 2022
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16“…Enzyme-linked immunosorbent assay (ELISA) was applied to detect the levels of relevant inflammatory mediators, reverse transcription-quantitative polymerase chain reaction (RT-qPCR) was used to measure the messenger RNA (mRNA) expression levels of serum necrosis factor-alpha (TNF-α), interleukin-6 (IL-6) and prostaglandin E2 (PGE2), and hematoxylin and eosin staining was utilized to detect the pathological characteristics of the synovial tissues. …”
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