Mostrando 1 - 20 Resultados de 24 Para Buscar '"Mycoplasma"', tiempo de consulta: 0.16s Limitar resultados
  1. 1
    “…Here, we use Single-Molecule Real-Time (SMRT) sequencing to determine the methylomes of two related human pathogen species, Mycoplasma genitalium G-37 and Mycoplasma pneumoniae M129, with single-base resolution. …”
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    Comprehensive Methylome Characterization of Mycoplasma genitalium and Mycoplasma pneumoniae at Single-Base Resolution
  2. 2
    “…Here we combine Hi-C and super-resolution microscopy to determine the structure of the Mycoplasma pneumoniae chromosome at a 10 kb resolution. …”
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    Defined chromosome structure in the genome-reduced bacterium Mycoplasma pneumoniae
  3. 3
    “…The human pathogen Mycoplasma pneumoniae is viable independently from host cells or organisms, despite its strongly reduced genome with only about 700 protein-coding genes. …”
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    MycoWiki: Functional annotation of the minimal model organism Mycoplasma pneumoniae
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    “…Mycoplasma pneumoniae, a threatening pathogen with a minimal genome, is a model organism for bacterial systems biology for which substantial experimental information is available. …”
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    Dissecting the energy metabolism in Mycoplasma pneumoniae through genome-scale metabolic modeling
  5. 5
    “…MyMpn (http://mympn.crg.eu) is an online resource devoted to studying the human pathogen Mycoplasma pneumoniae, a minimal bacterium causing lower respiratory tract infections. …”
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    MyMpn: a database for the systems biology model organism Mycoplasma pneumoniae
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    Comparative “-omics” in Mycoplasma pneumoniae Clinical Isolates Reveals Key Virulence Factors
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    “…Among them, Mycoplasma pneumoniae arises as a candidate for synthetic biology projects, as it is one of the most deeply characterized bacteria. …”
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    Mycoplasma pneumoniae Genome Editing Based on Oligo Recombineering and Cas9-Mediated Counterselection
  8. 8
    “…However, the function and conservation of FtsZ in wall-less prokaryotes such as mycoplasmas are less clear. In the genome-reduced bacterium Mycoplasma genitalium, the cell division gene cluster is limited to four genes: mraZ, mraW, MG_223, and ftsZ. …”
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    Functional Characterization of the Cell Division Gene Cluster of the Wall-less Bacterium Mycoplasma genitalium
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    “…To assist in the advancement of the large-scale production of safe Mycoplasma vaccines and other Mycoplasma-based therapies, we developed a culture medium free of animal serum and other animal components for Mycoplasma pneumoniae growth. …”
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    Development of a Serum-Free Medium To Aid Large-Scale Production of Mycoplasma-Based Therapies
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    “…Mycoplasma pneumoniae is a causative agent of atypical pneumonia. …”
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    A Trigger Enzyme in Mycoplasma pneumoniae: Impact of the Glycerophosphodiesterase GlpQ on Virulence and Gene Expression
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    “…To address this problem, we have studied the genome-reduced bacterium Mycoplasma pneumoniae, for which the RNAs associated with transcriptional start sites have been recently experimentally identified. …”
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    Distinguishing between productive and abortive promoters using a random forest classifier in Mycoplasma pneumoniae
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    “…Mycoplasma pneumoniae is a bacterial human pathogen that causes primary atypical pneumonia. …”
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    Immunodominant proteins P1 and P40/P90 from human pathogen Mycoplasma pneumoniae
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    “…We test this method in Mycoplasma pneumoniae, a bacterium with a very inefficient native recombination machinery. …”
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    SURE editing: combining oligo-recombineering and programmable insertion/deletion of selection markers to efficiently edit the Mycoplasma pneumoniae genome
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    “…Mycoplasmas are important model organisms for Systems and Synthetic Biology, and are pathogenic to a wide variety of species. …”
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    SynMyco transposon: engineering transposon vectors for efficient transformation of minimal genomes
  15. 15
    “…We use two bacterial species (Mycoplasma pneumoniae and Mycoplasma agalactiae) that share a high gene content similarity yet show significant metabolic differences. …”
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    Inferring Active Metabolic Pathways from Proteomics and Essentiality Data
  16. 16
    por Lluch-Senar, Maria
    Publicado 2023
    “…Here, we outline how we designed MycoChassis — an attenuated bacterium strain obtained by genome engineering of Mycoplasma pneumoniae (a human lung pathogen) — and discuss the challenges on the road to its clinical translation.…”
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    From science to business: translating live biotherapeutic products to the clinic
  17. 17
    “…We also show an example of how this incorrect annotation can induce toxic effects in bacteria that lack optimal DNA repair systems, exemplified by Mycoplasma pneumoniae .…”
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    Lox’d in translation: contradictions in the nomenclature surrounding common lox-site mutants and their implications in experiments
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    “…Here, we determined the relative importance of different transcriptional mechanisms in the genome-reduced bacterium Mycoplasma pneumoniae, by employing an array of experimental techniques under multiple genetic and environmental perturbations. …”
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    Determination of the Gene Regulatory Network of a Genome-Reduced Bacterium Highlights Alternative Regulation Independent of Transcription Factors
  19. 19
    “…Here, we characterize this quality control system in a genome-reduced bacterium, Mycoplasma pneumoniae (MPN), and perform a comparative analysis of protein quality control components in slow and fast-growing prokaryotes. …”
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    Widespread ribosome stalling in a genome-reduced bacterium and the need for translational quality control
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    “…These predictions were verified experimentally by overexpressing nine different asRNAs in Mycoplasma pneumoniae. Our results suggest that most of the antisense transcripts found in bacteria are the consequence of transcriptional noise, arising at spurious promoters throughout the genome.…”
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    Bacterial antisense RNAs are mainly the product of transcriptional noise
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