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    “…Similar trends were seen using the other case definition, except the decline in CA CRE rate since 2016 was not significant (Figure 3). [Figure: see text] [Figure: see text] [Figure: see text] CONCLUSION: Adjusted CRE incidence rates declined from 2016 to 2020 using current and prior case definitions but changes over time varied by epidemiologic class. …”
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    1928. Trends In Incidence of Carbapenem-Resistant Enterobacterales (CRE) In Seven US sites, 2016─2020
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    “…Hospitalization rates among those ≥ 75 years peaked in December 2020; the following month, January 2021, had the highest proportion of post-discharge mortality (22.6%) in this age group (Figure 2). Mortality among hospitalized adults ages ≥18 years with laboratory-confirmed COVID-19, COVID-19-Associated Hospitalization Surveillance Network, March 2020–April 2021 [Figure: see text] Figure 1 Hospitalization Rate and Mortality among laboratory-confirmed COVID-19 among adults ages ≥75 years, COVID-19 Associated Hospitalization Surveillance Network, March 2020–April 2021 [Figure: see text] Figure 2 CONCLUSION: Among all deaths in adults with a COVID-19-associated hospitalization, two-thirds occurred in-hospital and one-third occurred ≤ 60 days post-discharge. …”
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    1368. In-hospital and post-discharge mortality among adults with COVID-19 associated hospitalization, COVID-NET, March 2020–April 2021.
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    “…Vaccination coverage and antiviral receipt varied by season and age [Figures 1 and 2]. Overall, 31% (n=846) were vaccinated and 89% (n=2,408) received antivirals. …”
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    128. Characteristics and Outcomes of Pregnant Women Hospitalized with Influenza in the United States, Flusurv-net, 2010–2019
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    “…Those with multiple attempts generally used the same communication type for all attempts (204/250); of those who switched, the commonest switch was to the phone (39/46). [Figure: see text] [Figure: see text] CONCLUSION: Of the three communication types, the phone and app options were most popular, with a trend towards more phone use in older age groups. …”
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    533. Use of Different Communication Types for Telehealth for COVID-19 During Implementation of a State Telehealth Test to Treat Program in Minnesota
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    “…Incidence of vaccine-type NS-IPD decreased in all age groups (Figure 1), while incidence of NVT NS-IPD increased in all age groups (Figure 2). …”
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    180. Impact of Pneumococcal Conjugative Vaccine on Antibiotic Resistant Invasive Pneumococcal Disease in the United States
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    “…We used multivariable logistic regression to identify factors associated with COVID-19-associated hospitalization in persons with iSA infection and compared infection types and outcomes in iSA patients with and without prior COVID-19-associated hospitalization. [Figure: see text] RESULTS: Of 2,406 HA iSA cases reported, 146 (6.1%) had prior COVID-19-associated hospitalization. …”
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    740. Healthcare-associated invasive Staphylococcus aureus among adults with prior COVID-19-associated hospitalization, 2020
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    “…Most common viruses detected by clinical testing included respiratory syncytial virus (41%), rhinovirus/enterovirus (31%), and influenza (15%) (Figure 1). Systematic RT–PCR testing at MDH identified 1,600 (68%) patients positive for ≥1 respiratory virus, identifying previously unknown detections among 35% (820) of SARI patients (Figure 2). …”
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    Comparison of Respiratory Pathogen Detections from Routine Hospital Testing and Expanded Systematic Testing from the Minnesota Severe Acute Respiratory Illness Surveillance Program, 2015–2016
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    “…Compared with treated patients without an acute cardiovascular event, treated patients with aHF (Figure A) and aIHD (Figure B) were more likely to be older, currently/formerly use tobacco and have underlying conditions including cardiovascular disease, diabetes mellitus, and kidney disease. …”
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    1621. Acute Cardiovascular Events Among Adults Hospitalized with Influenza, FluSurv-NET, 2010–2018
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    “…Risk status by CURB-65 was less sensitive than PSI in predicting MV, vasopressor, or ECMO usage as well as death (figure). The specificity of CURB-65 and PSI was similar against all outcomes (figure). …”
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    94. Pneumonia Severity Scores Poorly Predict Severe Outcomes Among Adults Hospitalized with Influenza
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    “…The largest reductions were noted in PCV13-type IPD in both PLHIV (Figure 1) and non-PLHIV (Figure 2) for both periods (-46.8% for PLHIV and -45.9% for non-PLHIV in 2011–12; -60.3% for PLHIV and -65.8% for non-PLHIV in 2013–14). …”
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    Changes in invasive pneumococcal disease among adults living with HIV following introduction of 13-valent pneumococcal conjugate vaccine, 2008–2014
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    “…After imputing A subtype, the 2017–2018 season had the highest rates observed for H3N2 (62.8) and B (28.5) than in any previous season, and the third highest rate of H1N1 (13.5) (Figure 1A). During 2017–2018, rates in adult ≥65 years peaked 3 weeks before they peaked in children 0–4 years. …”
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    LB17. Age-Related Differences in Influenza Type/Subtype Among Patients Hospitalized with Influenza, FluSurv-NET—2017–2018
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    “…Data on the proportion of H1 results by age correlated well between FluSurv-NET and US virologic surveillance (Figure B). CONCLUSION: Influenza A H1 and H3 virus circulation patterns varied by age group during the 2018–2019 season. …”
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    LB19. Patterns of Influenza A Hospitalizations by Subtype and Age in the United States, FluSurv-NET, 2018–2019
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    “…The adjusted VE in 2013–14 was 68% (95% Confidence Interval: 34, 85), but was non-significant during the 2014–15 and 2015–16 seasons (Figure). Estimates of VE by influenza A subtypes varied substantially by year; VE against influenza B viruses was significant, but could not be stratified by year. …”
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    Vaccine effectiveness against influenza-associated hospitalization among children aged < 13 years using a hospital-based surveillance system in Minnesota, 2013 – 2016
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    “…The percentage of patients on fluoroquinolones was lower in 2015, while percentages of patients on carbapenems or cephalosporins were higher in 2015 than in 2011 (figure). [Image: see text] CONCLUSION: Some observed differences between 2011 and 2015 provide evidence of stewardship impact. …”
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    1859. Prevalence of Antimicrobial Use in US Hospital Patients, 2011 vs. 2015
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    “…The pathway categorized FQ treatment as supported for 646 (85.4%) and unsupported for 110 patients (14.6%) (figure). Almost half of unsupported treatment was due to a lack of compatible signs or symptoms of infection in a patient from whom an organism susceptible or likely susceptible to an FQ was identified from a nonsterile site (49/110 patients, 44.5%), suggesting colonization. …”
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    1009. Measuring the quality of fluoroquinolone prescribing in hospitals: results from the Emerging Infections Program Hospital Prevalence Survey Antimicrobial Quality Assessment
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    “…Among the three sites with four full years of data, a different trend was seen in each (Figure). Trends in GA and MN were statistically significant, and no significant trend was seen in OR. …”
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    Wide Range of Carbapenem-resistant Enterobacteriaceae Incidence and Trends in Emerging Infections Program Surveillance, 2012–2015
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    “…RESULTS: In 161 NHs (mean certified beds 118, 92% dual certified, 68% for-profit), the % of NHs reporting implementation of the 15 activities (figure) ranged from 25% (has a formulary of antibiotic agents, providers required to perform an antibiotic “time-out”) to 88% (providers required to document dose, duration and indication). …”
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    1836. Characteristics of Nursing Homes Associated With Self-reported Implementation of Centers for Disease Control and Prevention (CDC) Core Elements of Antibiotic Stewardship
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    “…Among the 1,268 antibacterials (figure), fluoroquinolones (15%), combination penicillins (8%), third-generation cephalosporins (8%), and glycopepetides (5%) ranked among the top 10 classes in use. …”
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    1831. Point Prevalence and Epidemiology of Antimicrobial Use in US Nursing Homes, 2017
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    “…Risk factors for recurrence were: injection drug use (IDU) (aOR; 1.38, 95% confidence interval [CI]: 1.15–1.65), central venous catheters (aOR; 1.35, 95% CI: 1.22–1.51), dialysis (aOR; 2.00, 95% CI: 1.74–2.31), and history of MRSA colonization (aOR; 1.35, 95% CI: 1.22–1.51) (figure). Recurrence was more likely for bloodstream infections (BSI) without another infection (aOR; 2.08, 95% CI: 1.74–2.48), endocarditis (aOR; 1.46, 95% CI: 1.16–1.55), and bone/joint infections (aOR; 1.38, 95% CI: 1.20–1.59), and less likely for pneumonia (aOR: 0.75, 95% CI: 0.64–0.89), compared with other initial infection types. …”
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    1230. Epidemiology and Risk Factors for Recurrent Invasive Methicillin-Resistant Staphylococcus aureus Infection: nine US States, 2006–2013
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    “…Among patients with influenza A(H1N1)pdm09, vaccination was associated with decreased odds of ICU admission (odds ratio (OR) 0.81; OR 0.72) and MV (OR 0.66; OR 0.54) in adults 18–64 and ≥65 years, respectively; decreased odds of pneumonia (OR 0.83), death (OR 0.64) and shortened ICU LOS (relative hazard (RH) 0.82) in adults 18–64 years; and shortened hospital LOS (RH 0.91) in adults ≥65 years (figure). Vaccination was not associated with attenuation of severe outcomes in patients with influenza A(H3N2) and B. …”
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    898. Influenza Vaccination Reduces Risk of Severe Outcomes among Adults Hospitalized with Influenza A(H1N1)pdm09, FluSurv-NET, 2013–2018
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