-
1por Németh, Tamás, Futosi, Krisztina, Szabó, Marcell, Aradi, Petra, Saito, Takashi, Mócsai, Attila, Jakus, Zoltán“…In this study, the in vivo functions of FcRγ ITAM tyrosines were characterized using wild type and ITAM tyrosine mutant (Y65F/Y76F) transgenic mice crossed to an FcRγ-deficient genetic background. …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
2por Walbaum, Stefan, Ambrosy, Benjamin, Schütz, Paula, Bachg, Anne C., Horsthemke, Markus, Leusen, Jeanette H.W., Mócsai, Attila, Hanley, Peter J.“…In summary, we show that (1) CR3 indeed mediates a slow sinking mode of phagocytosis, which is accentuated by deletion of ITAM adaptors or Syk, (2) CR3 induces phagocytic cup-like structures, driven by ITAM adaptors and Syk, and (3) CR3 is involved in forming and closing FcγR-mediated phagocytic cups.…”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
3“…Some of these signaling pathways shows similarity to immunoreceptor-like receptor signaling and involves important other enzymes (e.g., PLCγ2) and adapter proteins (such as the ITAM−bearing adapters DAP12 and the Fc-receptor γ-chain). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto