Mostrando 1 - 20 Resultados de 42 Para Buscar '"Drosophila melanogaster"', tiempo de consulta: 0.09s Limitar resultados
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    “…To answer these questions we used Drosophila melanogaster, because its chemosensory systems are well characterized and both the genotype and environment can be controlled precisely. …”
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    Plasticity of the Chemoreceptor Repertoire in Drosophila melanogaster
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    por Mackay, Trudy F. C., Richards, Stephen, Stone, Eric A., Barbadilla, Antonio, Ayroles, Julien F., Zhu, Dianhui, Casillas, Sònia, Han, Yi, Magwire, Michael M., Cridland, Julie M., Richardson, Mark F., Anholt, Robert R. H., Barrón, Maite, Bess, Crystal, Blankenburg, Kerstin Petra, Carbone, Mary Anna, Castellano, David, Chaboub, Lesley, Duncan, Laura, Harris, Zeke, Javaid, Mehwish, Jayaseelan, Joy Christina, Jhangiani, Shalini N., Jordan, Katherine W., Lara, Fremiet, Lawrence, Faye, Lee, Sandra L., Librado, Pablo, Linheiro, Raquel S., Lyman, Richard F., Mackey, Aaron J., Munidasa, Mala, Muzny, Donna Marie, Nazareth, Lynne, Newsham, Irene, Perales, Lora, Pu, Ling-Ling, Qu, Carson, Ràmia, Miquel, Reid, Jeffrey G., Rollmann, Stephanie M., Rozas, Julio, Saada, Nehad, Turlapati, Lavanya, Worley, Kim C., Wu, Yuan-Qing, Yamamoto, Akihiko, Zhu, Yiming, Bergman, Casey M., Thornton, Kevin R., Mittelman, David, Gibbs, Richard A.
    Publicado 2012
    “…Here, we describe the Drosophila melanogaster Genetic Reference Panel (DGRP), a community resource for analysis of population genomics and quantitative traits. …”
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    The Drosophila melanogaster Genetic Reference Panel
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    Systems Genetics of Complex Traits in Drosophila melanogaster
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    “…Little is known about the genetic basis of naturally occurring variation for sexually selected behavioral traits. Drosophila melanogaster, with its rich repertoire of courtship behavior and genomic and genetic resources, is an excellent model organism for addressing this question. …”
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    Heritable Variation in Courtship Patterns in Drosophila melanogaster
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    “…The amount of pigmentation on the abdomen of Drosophila melanogaster is a relatively simple morphological trait, which serves as a model for mapping the genetic basis of variation in complex phenotypes. …”
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    Genetic Architecture of Abdominal Pigmentation in Drosophila melanogaster
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    “…To gain insights in evolutionarily conserved genetic principles that regulate food intake, we took advantage of a model system, Drosophila melanogaster, in which food intake, environmental conditions and genetic background can be controlled precisely. …”
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    Quantitative Genetics of Food Intake in Drosophila melanogaster
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    “…Here, we assessed the genetic divergence between five Drosophila melanogaster lines selected for postponed senescence for over 170 generations (O lines) and five lines from the same base population maintained at a two week generation interval for over 850 generations (B lines). …”
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    The Genomic Basis of Postponed Senescence in Drosophila melanogaster
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    “…Here, we quantified genetic variation for micro-environmental plasticity for three quantitative traits in the inbred, sequenced lines of the Drosophila melanogaster Genetic Reference Panel. We found substantial genetic variation for micro-environmental plasticity for all traits, with broad sense heritabilities of the same magnitude or greater than those of trait means. …”
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    Genetic Architecture of Micro-Environmental Plasticity in Drosophila melanogaster
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    “…Whereas neural mechanisms that mediate the effects of these drugs are well-characterized, genetic factors that account for individual variation in susceptibility to substance abuse and addiction remain largely unknown. Drosophila melanogaster can serve as a translational model for studies on substance abuse, since flies have a dopamine transporter that can bind cocaine and methamphetamine, and exposure to these compounds elicits effects similar to those observed in people, suggesting conserved evolutionary mechanisms underlying drug responses. …”
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    Genetics of cocaine and methamphetamine consumption and preference in Drosophila melanogaster
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    “…Using whole-genome quantitative gene expression as a model, here we study how the genetic architecture of regulatory variation in gene expression changed in a population of fully sequenced inbred Drosophila melanogaster strains when flies developed in different environments (25 °C and 18 °C). …”
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    Genotype by environment interaction for gene expression in Drosophila melanogaster
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    “…Here, we present a nucleotide resolution catalog of single-nucleotide, multi-nucleotide, and structural variants in 39 Drosophila melanogaster Genetic Reference Panel inbred lines. …”
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    Genomic Variation and Its Impact on Gene Expression in Drosophila melanogaster
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    “…Here, we exploit natural variation in the inbred, sequenced lines of the Drosophila melanogaster Genetic Reference Panel (DGRP) to map genetic variants affecting recombination rate. …”
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    The Genetic Architecture of Natural Variation in Recombination Rate in Drosophila melanogaster
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    “…Here, we report that RNAi knockdown of Obp56h gene expression in Drosophila melanogaster enhances mating behavior by reducing courtship latency. …”
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    Obp56h Modulates Mating Behavior in Drosophila melanogaster
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    Genome-Wide Association Study of Circadian Behavior in Drosophila melanogaster
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    “…Here, we analyzed the pattern of genetic divergence between long-lived (O) Drosophila melanogaster lines selected for postponed reproductive senescence and unselected control (B) lines. …”
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    Genetic Basis of Increased Lifespan and Postponed Senescence in Drosophila melanogaster
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    “…We quantified spontaneous grooming behavior in 201 sequenced lines of the Drosophila melanogaster Genetic Reference Panel and observed significant genetic variation in spontaneous grooming, with broad-sense heritabilities of 0.25 and 0.24 in females and males, respectively. …”
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    Genetic Basis of Natural Variation in Spontaneous Grooming in Drosophila melanogaster
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    “…Here, we used RNA interference in Drosophila melanogaster to reduce expression of six genes (brm, osa, Snr1, SMC1, SMC3, vtd) orthologous to human genes associated with SSRIDDs and CdLS. …”
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    Genetic and Genomic Analyses of Drosophila melanogaster Models of Chromatin Modification Disorders
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    “…Oxidative stress resistance is a quantitative trait with population variation attributable to the interplay between genetic and environmental factors. Drosophila melanogaster provides an ideal system to study the genetics of variation for resistance to oxidative stress. …”
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    Genome-Wide Association Analysis of Oxidative Stress Resistance in Drosophila melanogaster
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    “…To identify genes affecting sensitivity and resistance to ROS-induced locomotor decline, we assessed locomotion of aged flies of the sequenced, wild-derived lines from the Drosophila melanogaster Genetics Reference Panel on standard medium and following chronic exposure to medium supplemented with 3 mM menadione sodium bisulfite (MSB). …”
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    Genome-Wide Association for Sensitivity to Chronic Oxidative Stress in Drosophila melanogaster
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    “…Previous studies have reported similar changes in Drosophila melanogaster in response to RJ. Here, we quantified viability, development time, body size, productivity, lifespan and genome wide transcript abundance of D. melanogaster reared on standard culture medium supplemented with increasing concentrations of RJ. …”
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    The Effects of Royal Jelly on Fitness Traits and Gene Expression in Drosophila melanogaster
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