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  1. 1
    “…Nonetheless, NKp46(neg-low)/CD56(dim)/CD16(neg) cells displayed a markedly defective cytotoxicity that could be reversed by blocking the inhibitory receptor CD94/NKG2A. …”
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    The early expansion of anergic NKG2A(pos)/CD56(dim)/CD16(neg) natural killer represents a therapeutic target in haploidentical hematopoietic stem cell transplantation
  2. 2
    “…In particular, the two main NK cell subsets are represented by the CD56(bright)/CD16(−/dim) and the CD56(dim)/CD16(bright) NK cells. Experimental evidences indicate that CD56(bright) and CD56(dim) NK cells represent different maturative stages of the NK cell developmental pathway. …”
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    New miRNA Signature Heralds Human NK Cell Subsets at Different Maturation Steps: Involvement of miR-146a-5p in the Regulation of KIR Expression
  3. 3
    “…Human NK cells are distinguished into CD56(bright)CD16(−) cells and CD56(dim)CD16(+) cells. These two subsets are conventionally associated with differential functional outcomes and are heterogeneous with respect to the expression of KIR and CD94/NKG2 heterodimers that represent the two major types of HLA-class I-specific receptors. …”
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    Features of Memory-Like and PD-1(+) Human NK Cell Subsets
  4. 4
    “…Only recently, a key role for CCR7 in promoting CD56(dim) NK cell migration toward lymphoid tissues has been described. …”
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    Human NK Cell Subsets Redistribution in Pathological Conditions: A Role for CCR7 Receptor
  5. 5
    “…We show that while in the peritoneal fluid (PF) of low-grade PC most CD56dim NK cells show a relatively immature phenotype (NKG2A+KIR–CD57–CD16dim), in the PF of high-grade PC NK cells are, in large majority, mature (CD56dimKIR+CD57+CD16bright). …”
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    Different Features of Tumor-Associated NK Cells in Patients With Low-Grade or High-Grade Peritoneal Carcinomatosis
  6. 6
    “…The analysis revealed that CD56(bright)CD16(neg) resulted higher in BAL than PB of sarcoidosis and healthy subjects, while CD56(dim)CD16(+) showed a different proportion between BAL and PB of both Sarcoidosis patients and HC. …”
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    Characterization of natural killer and T cells in bronchoalveolar lavage and peripheral blood of sarcoidosis patients
  7. 7
    “…PD-1 mRNA and protein were higher in CD56(dim) than in CD56(bright) NK cells. Confocal microscopy analyses revealed that PD-1 protein is present in virtually all NK cells analyzed. …”
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    PD-1 in human NK cells: evidence of cytoplasmic mRNA and protein expression
  8. 8
    “…PD-1 was present on CD56(dim) NKs, and particularly abundant on CD56(neg) NKs, but only rarely present on CD56(bright) NKs. …”
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    Identification of a novel cord blood NK cell subpopulation expressing functional programmed death receptor-1
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