Mostrando 1 - 20 Resultados de 22 Para Buscar '"Drosophila melanogaster"', tiempo de consulta: 0.12s Limitar resultados
  1. 1
    “…Here we report a microarray analysis of gene expression variation among females of 16 Drosophila melanogaster strains derived from natural populations, including eight strains from the putative ancestral range in sub-Saharan Africa and eight strains from Europe. …”
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    Population transcriptomics of Drosophila melanogaster females
  2. 2
    “…Recent microarray studies have revealed that expression variation is abundant in many species, including Drosophila melanogaster. However, previous expression surveys in this species generally focused on a small number of laboratory strains established from derived populations. …”
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    Gene expression variation in African and European populations of Drosophila melanogaster
  3. 3
    “…BACKGROUND: Bacterial and fungal infections induce a potent immune response in Drosophila melanogaster, but it is unclear whether viral infections induce an antiviral immune response. …”
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    The Transcriptional Response of Drosophila melanogaster to Infection with the Sigma Virus (Rhabdoviridae)
  4. 4
    “…Here we use high-throughput RNA sequencing of a single Drosophila melanogaster tissue to detect brain-specific differences in gene expression between the sexes and between two populations, one from the ancestral species range in sub-Saharan Africa and one from the recently colonized species range in Europe. …”
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    Population and sex differences in Drosophila melanogaster brain gene expression
  5. 5
    por Argyridou, Eliza, Parsch, John
    Publicado 2018
    “…Using bioinformatic and experimental approaches, we investigate the expression of the X chromosome in Drosophila melanogaster. We observe nearly complete X chromosome dosage compensation in male somatic tissues, but not in testis. …”
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    Regulation of the X Chromosome in the Germline and Soma of Drosophila melanogaster Males
  6. 6
    “…Cosmopolitan populations of Drosophila melanogaster are more tolerant to oxidative stress than those from the species’ ancestral range in sub-Saharan Africa, and the degree of tolerance is associated with an insertion/deletion polymorphism in the 3′ untranslated region of the Metallothionein A (MtnA) gene that varies clinally in frequency. …”
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    Natural variation in the transcriptional response of Drosophila melanogaster to oxidative stress
  7. 7
    por Huylmans, Ann Kathrin, Parsch, John
    Publicado 2014
    “…To investigate gene expression variation between sexes and populations in a single somatic tissue, we performed a quantitative analysis of the Malpighian tubule transcriptome in adult males and females of Drosophila melanogaster derived from two distinct populations (one from sub-Saharan Africa and one from northern Europe). …”
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    Population- and Sex-Biased Gene Expression in the Excretion Organs of Drosophila melanogaster
  8. 8
    “…Sex chromosomes often differ from autosomes with respect to their gene expression and regulation. In Drosophila melanogaster, X-linked genes are dosage compensated by having their expression upregulated in the male soma, a process mediated by the X-chromosome-specific binding of the dosage compensation complex (DCC). …”
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    The Influence of Chromosomal Environment on X-Linked Gene Expression in Drosophila melanogaster
  9. 9
    “…Drosophila melanogaster is an important model for antiviral immunity in arthropods, but very few DNA viruses have been described from the family Drosophilidae. …”
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    The discovery, distribution, and diversity of DNA viruses associated with Drosophila melanogaster in Europe
  10. 10
    por Glaser-Schmitt, Amanda, Parsch, John
    Publicado 2023
    “…Here, we examined coding and non-coding gene expression in the fat body of an ancestral African and a derived European Drosophila melanogaster population across three developmental stages spanning ten hours of larval development. …”
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    Dynamics and stage-specificity of between-population gene expression divergence in the Drosophila melanogaster larval fat body
  11. 11
    por Glaser-Schmitt, Amanda, Parsch, John
    Publicado 2018
    “…In this study, we perform a functional analysis of the Drosophila melanogaster CG9509 enhancer, a cis-regulatory element that shows evidence of adaptive evolution in populations outside the species’ ancestral range in sub-Saharan Africa. …”
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    Functional characterization of adaptive variation within a cis-regulatory element influencing Drosophila melanogaster growth
  12. 12
    “…Although gene expression can vary extensively within and among populations, the genetic basis of this variation and the evolutionary forces that maintain it are largely unknown. In Drosophila melanogaster, a 49-bp insertion/deletion (indel) polymorphism in the Metallothionein A (MtnA) gene is associated with variation in MtnA expression and oxidative stress tolerance. …”
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    Population Genetic and Functional Analysis of a cis-Regulatory Polymorphism in the Drosophila melanogaster Metallothionein A gene
  13. 13
    “…Here, we examined the maintenance of a regulatory single-nucleotide polymorphism (SNP) of the X-linked Drosophila melanogaster gene fezzik. The derived variant at this site is at intermediate frequency in many worldwide populations but absent in populations from the ancestral species range in sub-Saharan Africa. …”
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    Sexual Antagonism, Temporally Fluctuating Selection, and Variable Dominance Affect a Regulatory Polymorphism in Drosophila melanogaster
  14. 14
    “…We sequenced and assembled genomes with long-read technology and the corresponding transcriptomes from inbred lines of Drosophila melanogaster, derived from seven geographically diverse populations. …”
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    Population genomics reveals mechanisms and dynamics of de novo expressed open reading frame emergence in Drosophila melanogaster
  15. 15
    por Huylmans, Ann Kathrin, Parsch, John
    Publicado 2015
    “…Previous studies of Drosophila melanogaster found a general paucity of male-biased genes on the X chromosome, although this is mainly limited to comparisons of whole flies or body segments containing the reproductive organs. …”
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    Variation in the X:Autosome Distribution of Male-Biased Genes among Drosophila melanogaster Tissues and Its Relationship with Dosage Compensation
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    “…In this study we report that an indel polymorphism in the 3’ untranslated region (UTR) of the metallothionein gene MtnA is associated with gene expression variation in natural populations of Drosophila melanogaster. A derived allele of MtnA with a 49-bp deletion in the 3' UTR segregates at high frequency in populations outside of sub-Saharan Africa. …”
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    An Indel Polymorphism in the MtnA 3' Untranslated Region Is Associated with Gene Expression Variation and Local Adaptation in Drosophila melanogaster
  17. 17
    por Kapun, Martin, Barrón, Maite G, Staubach, Fabian, Obbard, Darren J, Wiberg, R Axel W, Vieira, Jorge, Goubert, Clément, Rota-Stabelli, Omar, Kankare, Maaria, Bogaerts-Márquez, María, Haudry, Annabelle, Waidele, Lena, Kozeretska, Iryna, Pasyukova, Elena G, Loeschcke, Volker, Pascual, Marta, Vieira, Cristina P, Serga, Svitlana, Montchamp-Moreau, Catherine, Abbott, Jessica, Gibert, Patricia, Porcelli, Damiano, Posnien, Nico, Sánchez-Gracia, Alejandro, Grath, Sonja, Sucena, Élio, Bergland, Alan O, Guerreiro, Maria Pilar Garcia, Onder, Banu Sebnem, Argyridou, Eliza, Guio, Lain, Schou, Mads Fristrup, Deplancke, Bart, Vieira, Cristina, Ritchie, Michael G, Zwaan, Bas J, Tauber, Eran, Orengo, Dorcas J, Puerma, Eva, Aguadé, Montserrat, Schmidt, Paul, Parsch, John, Betancourt, Andrea J, Flatt, Thomas, González, Josefa
    Publicado 2020
    “…Here, we address these issues using a collaborative approach, sequencing 48 pooled population samples from 32 locations, and perform the first continent-wide genomic analysis of genetic variation in European Drosophila melanogaster. Our analyses uncover longitudinal population structure, provide evidence for continent-wide selective sweeps, identify candidate genes for local climate adaptation, and document clines in chromosomal inversion and transposable element frequencies. …”
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    Genomic Analysis of European Drosophila melanogaster Populations Reveals Longitudinal Structure, Continent-Wide Selection, and Previously Unknown DNA Viruses
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    por Stamboliyska, Rayna, Parsch, John
    Publicado 2011
    “…In addition to providing a valuable resource for the community of mosquito researchers, the study allows comparative transcriptomic studies of dipteran insects to be extended over 250 million years of evolution, since the divergence of A. gambiae and Drosophila melanogaster.…”
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    Dissecting gene expression in mosquito
  19. 19
    “…We examined the molecular evolution of sex-biased genes in Drosophila melanogaster and D. ananassae, which represent two independent lineages within the melanogaster group. …”
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    Inter- and Intraspecific Variation in Drosophila Genes with Sex-Biased Expression
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    “…Genes with male- and testis-enriched expression are under-represented on the Drosophila melanogaster X chromosome. There is also an excess of retrotransposed genes, many of which are expressed in testis, that have “escaped” the X chromosome and moved to the autosomes. …”
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    X Chromosome Inactivation during Drosophila Spermatogenesis
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