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1por Bass, Edward James, Freeman, Alex, Jameson, Charles, Punwani, Shonit, Moore, Caroline M, Arya, Manit, Emberton, Mark, Ahmed, Hashim Uddin“…Cancer was detected in 45 (79%). 43 (96%) had University College London definition 2 disease or greater. …”
Publicado 2018
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2por Radtke, Jan Philipp, Giganti, Francesco, Wiesenfarth, Manuel, Stabile, Armando, Marenco, Jose, Orczyk, Clement, Kasivisvanathan, Veeru, Nyarangi-Dix, Joanne Nyaboe, Schütz, Viktoria, Dieffenbacher, Svenja, Görtz, Magdalena, Stenzinger, Albrecht, Roth, Wilfried, Freeman, Alex, Punwani, Shonit, Bonekamp, David, Schlemmer, Heinz-Peter, Hohenfellner, Markus, Emberton, Mark, Moore, Caroline M.“…Validity was tested by a consecutive cohort of biopsy-naïve men from Heidelberg (n = 160) and externally by a cohort of 133 men from University College London Hospital (UCLH). Assessment of validity was performed at fusion-biopsy by calibration plots, receiver operating characteristics curve and decision curve analyses. …”
Publicado 2019
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3por Giganti, Francesco, Pecoraro, Martina, Stavrinides, Vasilis, Stabile, Armando, Cipollari, Stefano, Sciarra, Alessandro, Kirkham, Alex, Allen, Clare, Punwani, Shonit, Emberton, Mark, Catalano, Carlo, Moore, Caroline M., Panebianco, Valeria“…Higher inter-reader agreement was observed for the scans performed at University College London (UCL) (κ = 0.81 vs 0.55 on a per-patient level and κ = 0.70 vs 0.48 on a per-scan level, respectively). …”
Publicado 2019
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4por Stavrinides, Vasilis, Giganti, Francesco, Trock, Bruce, Punwani, Shonit, Allen, Clare, Kirkham, Alex, Freeman, Alex, Haider, Aiman, Ball, Rhys, McCartan, Neil, Whitaker, Hayley, Orczyk, Clement, Emberton, Mark, Moore, Caroline M.“…DESIGN, SETTING, AND PARTICIPANTS: Data on 672 men enrolled in AS between August 2004 and November 2017 (inclusion criteria: Gleason 3 + 3 or 3 + 4 localised prostate cancer, presenting prostate-specific antigen <20 ng/ml, and baseline mpMRI) were collected from the University College London Hospital (UCLH) database. OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: Primary outcomes were event-free survival (EFS; event defined as prostate cancer treatment, transition to watchful waiting, or death) and treatment-free survival (TFS). …”
Publicado 2020
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5por Stavrinides, Vasilis, Syer, Tom, Hu, Yipeng, Giganti, Francesco, Freeman, Alex, Karapanagiotis, Solon, Bott, Simon R.J., Brown, Louise C., Burns-Cox, Nicholas, Dudderidge, Timothy J., Bosaily, Ahmed El-Shater, Frangou, Elena, Ghei, Maneesh, Henderson, Alastair, Hindley, Richard G., Kaplan, Richard S., Oldroyd, Robert, Parker, Chris, Persad, Raj, Rosario, Derek J., Shergill, Iqbal S., Echeverria, Lina M. Carmona, Norris, Joseph M., Winkler, Mathias, Barratt, Dean, Kirkham, Alex, Punwani, Shonit, Whitaker, Hayley C., Ahmed, Hashim U., Emberton, Mark“…DESIGN, SETTING, AND PARTICIPANTS: PROMIS participants (n = 235) underwent mpMRI followed by a combined biopsy procedure at University College London Hospital, including 5-mm TPM as the reference standard. …”
Publicado 2021
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6por Pye, Hayley, Singh, Saurabh, Norris, Joseph M., Carmona Echeverria, Lina M., Stavrinides, Vasilis, Grey, Alistair, Dinneen, Eoin, Pilavachi, Elly, Clemente, Joey, Heavey, Susan, Stopka-Farooqui, Urszula, Simpson, Benjamin S., Bonet-Carne, Elisenda, Patel, Dominic, Barker, Peter, Burling, Keith, Stevens, Nicola, Ng, Tony, Panagiotaki, Eleftheria, Hawkes, David, Alexander, Daniel C., Rodriguez-Justo, Manuel, Haider, Aiman, Freeman, Alex, Kirkham, Alex, Atkinson, David, Allen, Clare, Shaw, Greg, Beeston, Teresita, Brizmohun Appayya, Mrishta, Latifoltojar, Arash, Johnston, Edward W., Emberton, Mark, Moore, Caroline M., Ahmed, Hashim U., Punwani, Shonit, Whitaker, Hayley C.“…SIMPLE SUMMARY: As we start to see the increased, routine, use of multiparametric magnetic resonance imaging (mpMRI) to inform prostate cancer diagnosis and image-guided biopsy, data collected from University College London Hospital describes the expected diagnostic outcomes of PSA and PSA Density in this pathway as well as the potential space remaining for novel biomarkers to further improve the pathway. …”
Publicado 2021
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