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1por Wang, Sijia, Ray, Nicolas, Rojas, Winston, Parra, Maria V., Bedoya, Gabriel, Gallo, Carla, Poletti, Giovanni, Mazzotti, Guido, Hill, Kim, Hurtado, Ana M., Camrena, Beatriz, Nicolini, Humberto, Klitz, William, Barrantes, Ramiro, Molina, Julio A., Freimer, Nelson B., Bortolini, Maria Cátira, Salzano, Francisco M., Petzl-Erler, Maria L., Tsuneto, Luiza T., Dipierri, José E., Alfaro, Emma L., Bailliet, Graciela, Bianchi, Nestor O., Llop, Elena, Rothhammer, Francisco, Excoffier, Laurent, Ruiz-Linares, Andrés“…The large and diverse population of Latin America is potentially a powerful resource for elucidating the genetic basis of complex traits through admixture mapping. …”
Publicado 2008
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2por Paschetta, Carolina, de Azevedo, Soledad, Ramallo, Virginia, Cintas, Celia, Pérez, Orlando, Navarro, Pablo, Bandieri, Lucas, Sánchez, Mirsha Quinto, Adhikari, Kaustubh, Bortolini, M. Catira, Ferrara, Giovanni Poletti, Gallo, Carla, Bedoya, Gabriel, Rothhammer, Francisco, Alonzo, Victor Acuña, Ruiz-Linares, Andrés, González-José, Rolando“…We developed a comprehensive analysis of ethnic self-perception (ESP) on a large sample of Latin American mestizos from five countries, differing in age, socio-economic and education context, external phenotypic attributes and genetic background. …”
Publicado 2021
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3por Mendoza-Revilla, Javier, Chacón-Duque, J. Camilo, Fuentes-Guajardo, Macarena, Ormond, Louise, Wang, Ke, Hurtado, Malena, Villegas, Valeria, Granja, Vanessa, Acuña-Alonzo, Victor, Jaramillo, Claudia, Arias, William, Barquera, Rodrigo, Gómez-Valdés, Jorge, Villamil-Ramírez, Hugo, Silva de Cerqueira, Caio C., Badillo Rivera, Keyla M., Nieves-Colón, Maria A., Gignoux, Christopher R., Wojcik, Genevieve L., Moreno-Estrada, Andrés, Hünemeier, Tábita, Ramallo, Virginia, Schuler-Faccini, Lavinia, Gonzalez-José, Rolando, Bortolini, Maria-Cátira, Canizales-Quinteros, Samuel, Gallo, Carla, Poletti, Giovanni, Bedoya, Gabriel, Rothhammer, Francisco, Balding, David, Fumagalli, Matteo, Adhikari, Kaustubh, Ruiz-Linares, Andrés, Hellenthal, Garrett“…We apply this method to genome-wide SNP data of ∼4,000 individuals in five admixed Latin American cohorts from Brazil, Chile, Colombia, Mexico, and Peru. …”
Publicado 2022
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4por Yang, Guangrui, Chen, Yingjie, Li, Qing, Benítez, Daniel, Ramírez, Luis Miguel, Fuentes-Guajardo, Macarena, Hanihara, Tsunehiko, Scott, G. Richard, Acuña Alonzo, Victor, Gonzalez Jose, Rolando, Bortolini, Maria Catira, Poletti, Giovanni, Gallo, Carla, Rothhammer, Francisco, Rojas, Winston, Zanolli, Clément, Adhikari, Kaustubh, Ruiz-Linares, Andres, Delgado, Miguel“…Despite this, populations of mixed continental ancestry such as contemporary Latin Americans remain unexplored. In the present study we investigated a large Latin American sample from Colombia (N = 804) and obtained buccolingual and mesiodistal diameters and three indices for maxillary and mandibular teeth (except third molars). …”
Publicado 2023
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5por Quinto-Sánchez, Mirsha, Cintas, Celia, Silva de Cerqueira, Caio Cesar, Ramallo, Virginia, Acuña-Alonzo, Victor, Adhikari, Kaustubh, Castillo, Lucía, Gomez-Valdés, Jorge, Everardo, Paola, De Avila, Francisco, Hünemeier, Tábita, Jaramillo, Claudia, Arias, Williams, Fuentes, Macarena, Gallo, Carla, Poletti, Giovani, Schuler-Faccini, Lavinia, Bortolini, Maria Cátira, Canizales-Quinteros, Samuel, Rothhammer, Francisco, Bedoya, Gabriel, Rosique, Javier, Ruiz-Linares, Andrés, González-José, Rolando“…Here we aim to further evaluate such hypothesis on a large sample of admixed Latin Americans individuals by exploring if low socioeconomic status individuals tend to exhibit greater facial fluctuating asymmetry values. …”
Publicado 2017
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6por Adhikari, Kaustubh, Mendoza-Revilla, Javier, Sohail, Anood, Fuentes-Guajardo, Macarena, Lampert, Jodie, Chacón-Duque, Juan Camilo, Hurtado, Malena, Villegas, Valeria, Granja, Vanessa, Acuña-Alonzo, Victor, Jaramillo, Claudia, Arias, William, Lozano, Rodrigo Barquera, Everardo, Paola, Gómez-Valdés, Jorge, Villamil-Ramírez, Hugo, Silva de Cerqueira, Caio C., Hunemeier, Tábita, Ramallo, Virginia, Schuler-Faccini, Lavinia, Salzano, Francisco M., Gonzalez-José, Rolando, Bortolini, Maria-Cátira, Canizales-Quinteros, Samuel, Gallo, Carla, Poletti, Giovanni, Bedoya, Gabriel, Rothhammer, Francisco, Tobin, Desmond J., Fumagalli, Matteo, Balding, David, Ruiz-Linares, Andrés“…We report a genome-wide association scan in >6,000 Latin Americans for pigmentation of skin and eyes. …”
Publicado 2019
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7por Quinto-Sánchez, Mirsha, Cintas, Celia, Silva de Cerqueira, Caio Cesar, Ramallo, Virginia, Acuña-Alonzo, Victor, Adhikari, Kaustubh, Castillo, Lucía, Gomez-Valdés, Jorge, Everardo, Paola, De Avila, Francisco, Hünemeier, Tábita, Jaramillo, Claudia, Arias, Williams, Fuentes, Macarena, Gallo, Carla, Poletti, Giovani, Schuler-Faccini, Lavinia, Bortolini, Maria Cátira, Canizales-Quinteros, Samuel, Rothhammer, Francisco, Bedoya, Gabriel, Rosique, Javier, Ruiz-Linares, Andrés, González-José, RolandoEnlace del recurso
Publicado 2017
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8por Chacón-Duque, Juan-Camilo, Adhikari, Kaustubh, Fuentes-Guajardo, Macarena, Mendoza-Revilla, Javier, Acuña-Alonzo, Victor, Barquera, Rodrigo, Quinto-Sánchez, Mirsha, Gómez-Valdés, Jorge, Everardo Martínez, Paola, Villamil-Ramírez, Hugo, Hünemeier, Tábita, Ramallo, Virginia, Silva de Cerqueira, Caio C., Hurtado, Malena, Villegas, Valeria, Granja, Vanessa, Villena, Mercedes, Vásquez, René, Llop, Elena, Sandoval, José R., Salazar-Granara, Alberto A., Parolin, Maria-Laura, Sandoval, Karla, Peñaloza-Espinosa, Rosenda I., Rangel-Villalobos, Hector, Winkler, Cheryl A., Klitz, William, Bravi, Claudio, Molina, Julio, Corach, Daniel, Barrantes, Ramiro, Gomes, Verónica, Resende, Carlos, Gusmão, Leonor, Amorim, Antonio, Xue, Yali, Dugoujon, Jean-Michel, Moral, Pedro, González-José, Rolando, Schuler-Faccini, Lavinia, Salzano, Francisco M., Bortolini, Maria-Cátira, Canizales-Quinteros, Samuel, Poletti, Giovanni, Gallo, Carla, Bedoya, Gabriel, Rothhammer, Francisco, Balding, David, Hellenthal, Garrett, Ruiz-Linares, Andrés“…Historical records and genetic analyses indicate that Latin Americans trace their ancestry mainly to the intermixing (admixture) of Native Americans, Europeans and Sub-Saharan Africans. …”
Publicado 2018
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9por Ruiz-Linares, Andrés, Adhikari, Kaustubh, Acuña-Alonzo, Victor, Quinto-Sanchez, Mirsha, Jaramillo, Claudia, Arias, William, Fuentes, Macarena, Pizarro, María, Everardo, Paola, de Avila, Francisco, Gómez-Valdés, Jorge, León-Mimila, Paola, Hunemeier, Tábita, Ramallo, Virginia, Silva de Cerqueira, Caio C., Burley, Mari-Wyn, Konca, Esra, de Oliveira, Marcelo Zagonel, Veronez, Mauricio Roberto, Rubio-Codina, Marta, Attanasio, Orazio, Gibbon, Sahra, Ray, Nicolas, Gallo, Carla, Poletti, Giovanni, Rosique, Javier, Schuler-Faccini, Lavinia, Salzano, Francisco M., Bortolini, Maria-Cátira, Canizales-Quinteros, Samuel, Rothhammer, Francisco, Bedoya, Gabriel, Balding, David, Gonzalez-José, Rolando“…The current genetic makeup of Latin America has been shaped by a history of extensive admixture between Africans, Europeans and Native Americans, a process taking place within the context of extensive geographic and social stratification. …”
Publicado 2014
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10por Adhikari, Kaustubh, Fontanil, Tania, Cal, Santiago, Mendoza-Revilla, Javier, Fuentes-Guajardo, Macarena, Chacón-Duque, Juan-Camilo, Al-Saadi, Farah, Johansson, Jeanette A., Quinto-Sanchez, Mirsha, Acuña-Alonzo, Victor, Jaramillo, Claudia, Arias, William, Barquera Lozano, Rodrigo, Macín Pérez, Gastón, Gómez-Valdés, Jorge, Villamil-Ramírez, Hugo, Hunemeier, Tábita, Ramallo, Virginia, Silva de Cerqueira, Caio C., Hurtado, Malena, Villegas, Valeria, Granja, Vanessa, Gallo, Carla, Poletti, Giovanni, Schuler-Faccini, Lavinia, Salzano, Francisco M., Bortolini, Maria-Cátira, Canizales-Quinteros, Samuel, Rothhammer, Francisco, Bedoya, Gabriel, Gonzalez-José, Rolando, Headon, Denis, López-Otín, Carlos, Tobin, Desmond J., Balding, David, Ruiz-Linares, Andrés“…We report a genome-wide association scan in over 6,000 Latin Americans for features of scalp hair (shape, colour, greying, balding) and facial hair (beard thickness, monobrow, eyebrow thickness). …”
Publicado 2016
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11por Bonfante, Betty, Faux, Pierre, Navarro, Nicolas, Mendoza-Revilla, Javier, Dubied, Morgane, Montillot, Charlotte, Wentworth, Emma, Poloni, Lauriane, Varón-González, Ceferino, Jones, Philip, Xiong, Ziyi, Fuentes-Guajardo, Macarena, Palmal, Sagnik, Chacón-Duque, Juan Camilo, Hurtado, Malena, Villegas, Valeria, Granja, Vanessa, Jaramillo, Claudia, Arias, William, Barquera, Rodrigo, Everardo-Martínez, Paola, Sánchez-Quinto, Mirsha, Gómez-Valdés, Jorge, Villamil-Ramírez, Hugo, Silva de Cerqueira, Caio C., Hünemeier, Tábita, Ramallo, Virginia, Liu, Fan, Weinberg, Seth M., Shaffer, John R., Stergiakouli, Evie, Howe, Laurence J., Hysi, Pirro G., Spector, Timothy D., Gonzalez-José, Rolando, Schüler-Faccini, Lavinia, Bortolini, Maria-Cátira, Acuña-Alonzo, Victor, Canizales-Quinteros, Samuel, Gallo, Carla, Poletti, Giovanni, Bedoya, Gabriel, Rothhammer, Francisco, Thauvin-Robinet, Christel, Faivre, Laurence, Costedoat, Caroline, Balding, David, Cox, Timothy, Kayser, Manfred, Duplomb, Laurence, Yalcin, Binnaz, Cotney, Justin, Adhikari, Kaustubh, Ruiz-Linares, Andrés“…To characterize the genetic basis of facial features in Latin Americans, we performed a genome-wide association study (GWAS) of more than 6000 individuals using 59 landmark-based measurements from two-dimensional profile photographs and ~9,000,000 genotyped or imputed single-nucleotide polymorphisms. …”
Publicado 2021
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12por Faux, Pierre, Ding, Li, Ramirez-Aristeguieta, Luis Miguel, Chacón-Duque, J. Camilo, Comini, Maddalena, Mendoza-Revilla, Javier, Fuentes-Guajardo, Macarena, Jaramillo, Claudia, Arias, William, Hurtado, Malena, Villegas, Valeria, Granja, Vanessa, Barquera, Rodrigo, Everardo-Martínez, Paola, Quinto-Sánchez, Mirsha, Gómez-Valdés, Jorge, Villamil-Ramírez, Hugo, Silva de Cerqueira, Caio C., Hünemeier, Tábita, Ramallo, Virginia, Gonzalez-José, Rolando, Schüler-Faccini, Lavinia, Bortolini, Maria-Cátira, Acuña-Alonzo, Victor, Canizales-Quinteros, Samuel, Poletti, Giovanni, Gallo, Carla, Rothhammer, Francisco, Rojas, Winston, Schmid, Annina B., Adhikari, Kaustubh, Bennett, David L., Ruiz-Linares, Andrés“…In 1000 genomes data, these variants are absent in Europeans but common in Latin Americans. Analysing high-density genotype data from 7594 Latin Americans, we characterized Neanderthal introgression in SCN9A. …”
Publicado 2023
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13por Wu, Sijie, Zhang, Manfei, Yang, Xinzhou, Peng, Fuduan, Zhang, Juan, Tan, Jingze, Yang, Yajun, Wang, Lina, Hu, Yanan, Peng, Qianqian, Li, Jinxi, Liu, Yu, Guan, Yaqun, Chen, Chen, Hamer, Merel A., Nijsten, Tamar, Zeng, Changqing, Adhikari, Kaustubh, Gallo, Carla, Poletti, Giovanni, Schuler-Faccini, Lavinia, Bortolini, Maria-Cátira, Canizales-Quinteros, Samuel, Rothhammer, Francisco, Bedoya, Gabriel, González-José, Rolando, Li, Hui, Krutmann, Jean, Liu, Fan, Kayser, Manfred, Ruiz-Linares, Andres, Tang, Kun, Xu, Shuhua, Zhang, Liang, Jin, Li, Wang, Sijia“…We further replicated our findings in the Uyghurs, a population from China characterized by East Asian-European admixture (N = 721), the CANDELA cohort from five Latin American countries (N = 2301), and the Rotterdam Study cohort of Dutch Europeans (N = 4411). …”
Publicado 2018
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14por Schmid, Annina B, Adhikari, Kaustubh, Ramirez-Aristeguieta, Luis Miguel, Chacón-Duque, Juan-Camilo, Poletti, Giovanni, Gallo, Carla, Rothhammer, Francisco, Bedoya, Gabriel, Ruiz-Linares, Andres, Bennett, David L“…This protocol describes a proposed GWAS on genetic contributions to baseline pain sensitivity and nociceptive sensitisation in a sample of unrelated healthy individuals of mixed Latin American ancestry. METHODS AND ANALYSIS: A GWAS on genetic contributions to pain sensitivity in the naïve state and following nociceptive sensitisation will be conducted in unrelated healthy individuals of mixed ancestry. …”
Publicado 2019
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15por Li, Yi, Xiong, Ziyi, Zhang, Manfei, Hysi, Pirro G., Qian, Yu, Adhikari, Kaustubh, Weng, Jun, Wu, Sijie, Du, Siyuan, Gonzalez-Jose, Rolando, Schuler-Faccini, Lavinia, Bortolini, Maria-Catira, Acuna-Alonzo, Victor, Canizales-Quinteros, Samuel, Gallo, Carla, Poletti, Giovanni, Bedoya, Gabriel, Rothhammer, Francisco, Wang, Jiucun, Tan, Jingze, Yuan, Ziyu, Jin, Li, Uitterlinden, André G., Ghanbari, Mohsen, Ikram, M. Arfan, Nijsten, Tamar, Zhu, Xiangyu, Lei, Zhen, Jia, Peilin, Ruiz-Linares, Andres, Spector, Timothy D., Wang, Sijia, Kayser, Manfred, Liu, Fan“…In this study, we quantitatively assessed 136 ear morphology traits using deep learning analysis of digital face images in 14,921 individuals from five different cohorts in Europe, Asia, and Latin America. Through GWAS meta-analysis and C-GWASs, a recently introduced method to effectively combine GWASs of many traits, we identified 16 genetic loci involved in various ear phenotypes, eight of which have not been previously associated with human ear features. …”
Publicado 2023
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16por Adhikari, Kaustubh, Reales, Guillermo, Smith, Andrew J. P., Konka, Esra, Palmen, Jutta, Quinto-Sanchez, Mirsha, Acuña-Alonzo, Victor, Jaramillo, Claudia, Arias, William, Fuentes, Macarena, Pizarro, María, Barquera Lozano, Rodrigo, Macín Pérez, Gastón, Gómez-Valdés, Jorge, Villamil-Ramírez, Hugo, Hunemeier, Tábita, Ramallo, Virginia, Silva de Cerqueira, Caio C., Hurtado, Malena, Villegas, Valeria, Granja, Vanessa, Gallo, Carla, Poletti, Giovanni, Schuler-Faccini, Lavinia, Salzano, Francisco M., Bortolini, Maria- Cátira, Canizales-Quinteros, Samuel, Rothhammer, Francisco, Bedoya, Gabriel, Calderón, Rosario, Rosique, Javier, Cheeseman, Michael, Bhutta, Mahmood F., Humphries, Steve E., Gonzalez-José, Rolando, Headon, Denis, Balding, David, Ruiz-Linares, Andrés“…Here we report a genome-wide association study for non-pathological pinna morphology in over 5,000 Latin Americans. We find genome-wide significant association at seven genomic regions affecting: lobe size and attachment, folding of antihelix, helix rolling, ear protrusion and antitragus size (linear regression P values 2 × 10(−8) to 3 × 10(−14)). …”
Publicado 2015
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17por Koenigstein, Fabienne, Boekstegers, Felix, Wilson, James F, Fuentes-Guajardo, Macarena, Gonzalez-Jose, Rolando, Bedoya, Gabriel, Bortolini, Maria Cátira, Acuña-Alonzo, Victor, Gallo, Carla, Ruiz Linares, Andres, Rothhammer, Francisco, Lorenzo Bermejo, Justo“…The Native American genome typically exhibits long stretches of homozygosity, and Latin Americans are highly heterogeneous regarding the individual burden of homozygosity, the proportion and the type of Native American ancestry. …”
Publicado 2021
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18por Adhikari, Kaustubh, Fuentes-Guajardo, Macarena, Quinto-Sánchez, Mirsha, Mendoza-Revilla, Javier, Camilo Chacón-Duque, Juan, Acuña-Alonzo, Victor, Jaramillo, Claudia, Arias, William, Lozano, Rodrigo Barquera, Pérez, Gastón Macín, Gómez-Valdés, Jorge, Villamil-Ramírez, Hugo, Hunemeier, Tábita, Ramallo, Virginia, Silva de Cerqueira, Caio C., Hurtado, Malena, Villegas, Valeria, Granja, Vanessa, Gallo, Carla, Poletti, Giovanni, Schuler-Faccini, Lavinia, Salzano, Francisco M., Bortolini, Maria- Cátira, Canizales-Quinteros, Samuel, Cheeseman, Michael, Rosique, Javier, Bedoya, Gabriel, Rothhammer, Francisco, Headon, Denis, González-José, Rolando, Balding, David, Ruiz-Linares, Andrés“…We report a genome-wide association scan for facial features in ∼6,000 Latin Americans. We evaluated 14 traits on an ordinal scale and found significant association (P values<5 × 10(−8)) at single-nucleotide polymorphisms (SNPs) in four genomic regions for three nose-related traits: columella inclination (4q31), nose bridge breadth (6p21) and nose wing breadth (7p13 and 20p11). …”
Publicado 2016
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19por Lorenzo Bermejo, Justo, Boekstegers, Felix, González Silos, Rosa, Marcelain, Katherine, Baez Benavides, Pablo, Barahona Ponce, Carol, Müller, Bettina, Ferreccio, Catterina, Koshiol, Jill, Fischer, Christine, Peil, Barbara, Sinsheimer, Janet, Fuentes Guajardo, Macarena, Barajas, Olga, Gonzalez-Jose, Rolando, Bedoya, Gabriel, Cátira Bortolini, Maria, Canizales-Quinteros, Samuel, Gallo, Carla, Ruiz Linares, Andres, Rothhammer, Francisco“…Latin Americans are highly heterogeneous regarding the type of Native American ancestry. …”
Publicado 2017
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20por Quinto-Sánchez, Mirsha, Muñoz-Muñoz, Francesc, Gomez-Valdes, Jorge, Cintas, Celia, Navarro, Pablo, Cerqueira, Caio Cesar Silva de, Paschetta, Carolina, de Azevedo, Soledad, Ramallo, Virginia, Acuña-Alonzo, Victor, Adhikari, Kaustubh, Fuentes-Guajardo, Macarena, Hünemeier, Tábita, Everardo, Paola, de Avila, Francisco, Jaramillo, Claudia, Arias, Williams, Gallo, Carla, Poletti, Giovani, Bedoya, Gabriel, Bortolini, Maria Cátira, Canizales-Quinteros, Samuel, Rothhammer, Francisco, Rosique, Javier, Ruiz-Linares, Andres, Gonzalez-Jose, Rolando“…Here we explore several modularity hypotheses on a sample of Latin American mestizos, in order to test if modularity and integration patterns differ across several genomic ancestry backgrounds. …”
Publicado 2018
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