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1por Mansfield, Kathryn E., Schmidt, Sigrún A. J., Darvalics, Bianka, Mulick, Amy, Abuabara, Katrina, Wong, Angel Y. S., Sørensen, Henrik Toft, Smeeth, Liam, Bhaskaran, Krishnan, dos Santos Silva, Isabel, Silverwood, Richard J., Langan, Sinéad M.“…Participants with atopic eczema (adults only in England and any age in Denmark) were matched on age, sex, and calendar period (as well as primary care practice in England only) to those without atopic eczema. …”
Publicado 2020
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3por Davidson, Jennifer, Banerjee, Amitava, Mathur, Rohini, Ramsay, Mary, Smeeth, Liam, Walker, Jemma, McDonald, Helen, Warren-Gash, Charlotte“…We therefore aimed to investigate the incidence of clinically diagnosed influenza/influenza-like illness (ILI) by ethnicity in England from 2008-2018. Methods: We used linked primary and secondary healthcare data (from the Clinical Practice Research Datalink [CPRD] GOLD and Aurum databases and Hospital Episodes Statistics Admitted Patient Care [HES APC]). …”
Publicado 2021
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4por Davidson, Jennifer A, Banerjee, Amitava, Strongman, Helen, Herrett, Emily, Smeeth, Liam, Breuer, Judith, Warren-Gash, Charlotte“…PURPOSE: To assess the risk of incident cardiovascular outcomes after COVID-19 by level of cardiovascular risk in waves one and two of the pandemic in England in 2020. PATIENTS AND METHODS: We conducted a self-controlled case-series study among adults aged 40–84 years with no pre-existing cardiovascular disease using linked data from the Clinical Practice Research Datalink. …”
Publicado 2023
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5por Lin, Liang-Yu, Mulick, Amy, Mathur, Rohini, Smeeth, Liam, Warren-Gash, Charlotte, Langan, Sinéad M.“…We included people with at least one serum vitamin D test, living in England with linked primary care and inpatient records. …”
Publicado 2022
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6por Warren-Gash, Charlotte, Davidson, Jennifer A., Strongman, Helen, Herrett, Emily, Smeeth, Liam, Breuer, Judith, Banerjee, Amitava“…METHODS: We carried out historical, population-based cohort studies among adults aged 40–84 years in England using linked data from the Clinical Practice Research Datalink. …”
Publicado 2023
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7por Warren-Gash, Charlotte, Hayward, Andrew C., Hemingway, Harry, Denaxas, Spiros, Thomas, Sara L., Timmis, Adam D., Whitaker, Heather, Smeeth, LiamEnlace del recurso
Publicado 2012
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8por Pujades-Rodriguez, Mar, Duyx, Bram, Thomas, Sara L., Stogiannis, Dimitris, Rahman, Anisur, Smeeth, Liam, Hemingway, Harry“…METHODS: CALIBER data, which links primary care, hospital and mortality data in England, was analysed. A cohort of people aged ≥18 years and without history of CVD was assembled and included all patients with prospectively recorded rheumatoid arthritis from January 1997, until March 2010, matched with up to ten people without rheumatoid arthritis by age, sex and general practice. …”
Publicado 2016
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9por Rowan, Anna, Bates, Chris, Hulme, William, Evans, David, Davy, Simon, A Kennedy, Nicholas, Galloway, James, E Mansfield, Kathryn, Bechman, Katie, Matthewman, Julian, Yates, Mark, Brown, Jeremy, Schultze, Anna, Norton, Sam, J. Walker, Alex, E. Morton, Caroline, Bhaskaran, Krishnan, T. Rentsch, Christopher, Williamson, Elizabeth, Croker, Richard, Bacon, Seb, Hickman, George, Ward, Tom, Green, Amelia, Fisher, Louis, J Curtis, Helen, Tazare, John, M. Eggo, Rosalind, Inglesby, Peter, Cockburn, Jonathan, I. McDonald, Helen, Mathur, Rohini, YS Wong, Angel, Forbes, Harriet, Parry, John, Hester, Frank, Harper, Sam, J Douglas, Ian, Smeeth, Liam, A Tomlinson, Laurie, W Lees, Charlie, Evans, Stephen, Smith, Catherine, M. Langan, Sinéad, Mehkar, Amir, MacKenna, Brian, Goldacre, Ben“…With the approval of NHS England, we set out to obtain data on one specific group of medicines, “high-cost drugs” (HCD) which are typically specialist medicines for the management of long-term conditions, prescribed by hospitals to patients. …”
Publicado 2021
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10por Forbes, Harriet, Morton, Caroline E, Bacon, Seb, McDonald, Helen I, Minassian, Caroline, Brown, Jeremy P, Rentsch, Christopher T, Mathur, Rohini, Schultze, Anna, DeVito, Nicholas J, MacKenna, Brian, Hulme, William J, Croker, Richard, Walker, Alex J, Williamson, Elizabeth J, Bates, Chris, Mehrkar, Amir, Curtis, Helen J, Evans, David, Wing, Kevin, Inglesby, Peter, Drysdale, Henry, Wong, Angel Y S, Cockburn, Jonathan, McManus, Robert, Parry, John, Hester, Frank, Harper, Sam, Douglas, Ian J, Smeeth, Liam, Evans, Stephen J W, Bhaskaran, Krishnan, Eggo, Rosalind M, Goldacre, Ben, Tomlinson, Laurie A“…DESIGN: Population based cohort study, on behalf of NHS England. SETTING: Primary care data and pseudonymously linked hospital and intensive care admissions and death records from England, during wave 1 (1 February to 31 August 2020) and wave 2 (1 September to 18 December 2020). …”
Publicado 2021
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11por Bidulka, Patrick, Mathur, Rohini, Lugo‐Palacios, David G., O'Neill, Stephen, Basu, Anirban, Silverwood, Richard J., Charlton, Paul, Briggs, Andrew, Smeeth, Liam, Adler, Amanda I., Douglas, Ian J., Khunti, Kamlesh, Grieve, Richard“…AIMS: To assess any disparities in the initiation of second‐line antidiabetic treatments prescribed among people with type 2 diabetes mellitus (T2DM) in England according to ethnicity and social deprivation level. …”
Publicado 2022
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12por Tazare, John, Walker, Alex J., Tomlinson, Laurie A., Hickman, George, Rentsch, Christopher T., Williamson, Elizabeth J., Bhaskaran, Krishnan, Evans, David, Wing, Kevin, Mathur, Rohini, Wong, Angel YS., Schultze, Anna, Bacon, Seb, Bates, Chris, Morton, Caroline E., Curtis, Helen J., Nightingale, Emily, McDonald, Helen I., Mehrkar, Amir, Inglesby, Peter, Davy, Simon, MacKenna, Brian, Cockburn, Jonathan, Hulme, William J., Warren-Gash, Charlotte, Bhate, Ketaki, Nitsch, Dorothea, Powell, Emma, Mulick, Amy, Forbes, Harriet, Minassian, Caroline, Croker, Richard, Parry, John, Hester, Frank, Harper, Sam, Eggo, Rosalind M., Evans, Stephen JW., Smeeth, Liam, Douglas, Ian J, Goldacre, Ben“…Methods: Working on behalf of NHS England, we used linked primary care records, death certificate and hospital data from the OpenSAFELY platform. …”
Publicado 2022
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13por McDonald, Helen I, Tessier, Elise, White, Joanne M, Woodruff, Matthew, Knowles, Charlotte, Bates, Chris, Parry, John, Walker, Jemma L, Scott, J Anthony, Smeeth, Liam, Yarwood, Joanne, Ramsay, Mary, Edelstein, Michael“…Using electronic health records, we assessed the early impact of coronavirus disease (COVID-19) on routine childhood vaccination in England by 26 April 2020. Measles-mumps-rubella vaccination counts fell from February 2020, and in the 3 weeks after introduction of physical distancing measures were 19.8% lower (95% confidence interval: −20.7 to −18.9) than the same period in 2019, before improving in mid-April. …”
Publicado 2020
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14por Curtis, Helen J, MacKenna, Brian, Croker, Richard, Inglesby, Peter, Walker, Alex J, Morley, Jessica, Mehrkar, Amir, Morton, Caroline E, Bacon, Seb, Hickman, George, Bates, Chris, Evans, David, Ward, Tom, Cockburn, Jonathan, Davy, Simon, Bhaskaran, Krishnan, Schultze, Anna, Rentsch, Christopher T, Williamson, Elizabeth J, Hulme, William J, McDonald, Helen I, Tomlinson, Laurie, Mathur, Rohini, Drysdale, Henry, Eggo, Rosalind M, Wing, Kevin, Wong, Angel YS, Forbes, Harriet, Parry, John, Hester, Frank, Harper, Sam, Evans, Stephen JW, Douglas, Ian J, Smeeth, Liam, Goldacre, Ben“…DESIGN AND SETTING: Working on behalf of NHS England, a cohort study was conducted of 23.8 million patient records in general practice, in situ using OpenSAFELY. …”
Publicado 2021
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15por Walker, Jemma L, Schultze, Anna, Tazare, John, Tamborska, Arina, Singh, Bhagteshwar, Donegan, Katherine, Stowe, Julia, Morton, Caroline E, Hulme, William J, Curtis, Helen J, Williamson, Elizabeth J, Mehrkar, Amir, Eggo, Rosalind M, Rentsch, Christopher T, Mathur, Rohini, Bacon, Sebastian, Walker, Alex J, Davy, Simon, Evans, David, Inglesby, Peter, Hickman, George, MacKenna, Brian, Tomlinson, Laurie, CA Green, Amelia, Fisher, Louis, Cockburn, Jonathan, Parry, John, Hester, Frank, Harper, Sam, Bates, Christopher, Evans, Stephen JW, Solomon, Tom, Andrews, Nick J, Douglas, Ian J, Goldacre, Ben, Smeeth, Liam, McDonald, Helen I“…METHODS: With the approval of NHS England we analysed primary care data from >17 million patients in England linked to emergency care, hospital admission and mortality records in the OpenSAFELY platform. …”
Publicado 2022
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16por Green, Amelia, Curtis, Helen, Hulme, William, Williamson, Elizabeth, McDonald, Helen, Bhaskaran, Krishnan, Rentsch, Christopher, Schultze, Anna, MacKenna, Brian, Mahalingasivam, Viyaasan, Tomlinson, Laurie, Walker, Alex, Fisher, Louis, Massey, Jon, Andrews, Colm, Hopcroft, Lisa, Morton, Caroline, Croker, Richard, Morley, Jessica, Mehrkar, Amir, Bacon, Seb, Evans, David, Inglesby, Peter, Hickman, George, Ward, Tom, Davy, Simon, Mathur, Rohini, Tazare, John, Eggo, Rosalind, Wing, Kevin, Wong, Angel, Forbes, Harriet, Bates, Chris, Cockburn, Jonathan, Parry, John, Hester, Frank, Harper, Sam, Douglas, Ian, Evans, Stephen, Smeeth, Liam, Goldacre, Ben“…CONCLUSIONS: While the majority of COVID-19 vaccine breakthrough cases in England were mild, some differences in rates of breakthrough cases have been identified in several clinical groups. …”
Publicado 2022
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17por Newton, John N, Briggs, Adam D M, Murray, Christopher J L, Dicker, Daniel, Foreman, Kyle J, Wang, Haidong, Naghavi, Mohsen, Forouzanfar, Mohammad H, Ohno, Summer Lockett, Barber, Ryan M, Vos, Theo, Stanaway, Jeffrey D, Schmidt, Jürgen C, Hughes, Andrew J, Fay, Derek F J, Ecob, Russell, Gresser, Charis, McKee, Martin, Rutter, Harry, Abubakar, Ibrahim, Ali, Raghib, Anderson, H Ross, Banerjee, Amitava, Bennett, Derrick A, Bernabé, Eduardo, Bhui, Kamaldeep S, Biryukov, Stanley M, Bourne, Rupert R, Brayne, Carol E G, Bruce, Nigel G, Brugha, Traolach S, Burch, Michael, Capewell, Simon, Casey, Daniel, Chowdhury, Rajiv, Coates, Matthew M, Cooper, Cyrus, Critchley, Julia A, Dargan, Paul I, Dherani, Mukesh K, Elliott, Paul, Ezzati, Majid, Fenton, Kevin A, Fraser, Maya S, Fürst, Thomas, Greaves, Felix, Green, Mark A, Gunnell, David J, Hannigan, Bernadette M, Hay, Roderick J, Hay, Simon I, Hemingway, Harry, Larson, Heidi J, Looker, Katharine J, Lunevicius, Raimundas, Lyons, Ronan A, Marcenes, Wagner, Mason-Jones, Amanda J, Matthews, Fiona E, Moller, Henrik, Murdoch, Michele E, Newton, Charles R, Pearce, Neil, Piel, Frédéric B, Pope, Daniel, Rahimi, Kazem, Rodriguez, Alina, Scarborough, Peter, Schumacher, Austin E, Shiue, Ivy, Smeeth, Liam, Tedstone, Alison, Valabhji, Jonathan, Williams, Hywel C, Wolfe, Charles D A, Woolf, Anthony D, Davis, Adrian C J“…Outputs of this analysis are relevant to current policy questions in England and elsewhere, particularly on health inequalities. …”
Publicado 2015
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18por Grint, Daniel J, Wing, Kevin, Williamson, Elizabeth, McDonald, Helen I, Bhaskaran, Krishnan, Evans, David, Evans, Stephen JW, Walker, Alex J, Hickman, George, Nightingale, Emily, Schultze, Anna, Rentsch, Christopher T, Bates, Chris, Cockburn, Jonathan, Curtis, Helen J, Morton, Caroline E, Bacon, Sebastian, Davy, Simon, Wong, Angel YS, Mehrkar, Amir, Tomlinson, Laurie, Douglas, Ian J, Mathur, Rohini, Blomquist, Paula, MacKenna, Brian, Ingelsby, Peter, Croker, Richard, Parry, John, Hester, Frank, Harper, Sam, DeVito, Nicholas J, Hulme, Will, Tazare, John, Goldacre, Ben, Smeeth, Liam, Eggo, Rosalind M“…We found increased risk of death for VOC compared with non-VOC cases in England (hazard ratio: 1.67; 95% confidence interval: 1.34–2.09; p < 0.0001). …”
Publicado 2021
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19por Grint, Daniel J, Wing, Kevin, Houlihan, Catherine, Gibbs, Hamish P, Evans, Stephen J W, Williamson, Elizabeth, McDonald, Helen I, Bhaskaran, Krishnan, Evans, David, Walker, Alex J, Hickman, George, Nightingale, Emily, Schultze, Anna, Rentsch, Christopher T, Bates, Chris, Cockburn, Jonathan, Curtis, Helen J, Morton, Caroline E, Bacon, Sebastian, Davy, Simon, Wong, Angel Y S, Mehrkar, Amir, Tomlinson, Laurie, Douglas, Ian J, Mathur, Rohini, MacKenna, Brian, Ingelsby, Peter, Croker, Richard, Parry, John, Hester, Frank, Harper, Sam, DeVito, Nicholas J, Hulme, Will, Tazare, John, Smeeth, Liam, Goldacre, Ben, Eggo, Rosalind M“…METHODS: With the approval of NHS England, we linked individual-level data from primary care with SARS-CoV-2 community testing, hospital admission, and Office for National Statistics all-cause death data. …”
Publicado 2021
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20por Milojevic, Ai, Wilkinson, Paul, Armstrong, Ben, Bhaskaran, Krishnan, Smeeth, Liam, Hajat, Shakoor“…OBJECTIVE: To inform potential pathophysiological mechanisms of air pollution effects on cardiovascular disease (CVD), we investigated short-term associations between ambient air pollution and a range of cardiovascular events from three national databases in England and Wales. METHODS: Using a time-stratified case-crossover design, over 400 000 myocardial infarction (MI) events from the Myocardial Ischaemia National Audit Project (MINAP) database, over 2 million CVD emergency hospital admissions and over 600 000 CVD deaths were linked with daily mean concentrations of carbon monoxide (CO), nitrogen dioxide (NO(2)), particulate matter less than 10 μm in aerodynamic diameter (PM(10)), particulate matter less than 2.5 μm in aerodynamic diameter (PM(2.5)) and sulfur dioxide (SO(2)), and daily maximum of 8-hourly running mean of O(3) measured at the nearest air pollution monitoring site to the place of residence. …”
Publicado 2014
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