Mostrando 1 - 18 Resultados de 18 Para Buscar 'POPULATION DYNAMICS', tiempo de consulta: 0.47s Limitar resultados
  1. 1
    “…One of the central objectives in the field of phylodynamics is the quantification of population dynamic processes using genetic sequence data or in some cases phenotypic data. …”
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    How well can the exponential-growth coalescent approximate constant-rate birth–death population dynamics?
  2. 2
    por Seidel, Sophie, Stadler, Tanja
    Publicado 2022
    “…The development of organisms and tissues is dictated by an elaborate balance between cell division, apoptosis and differentiation: the cell population dynamics. To quantify these dynamics, we propose a phylodynamic inference approach based on single-cell lineage recorder data. …”
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    TiDeTree: a Bayesian phylogenetic framework to estimate single-cell trees and population dynamic parameters from genetic lineage tracing data
  3. 3
    por Seidel, Sophie, Stadler, Tanja
    Publicado 2023
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    Correction to: ‘TiDeTree: a Bayesian phylogenetic framework to estimate single-cell trees and population dynamic parameters from genetic lineage tracing data’ (2022) by Seidel & Stadler
  4. 4
    “…Estimation of epidemiological and population parameters from molecular sequence data has become central to the understanding of infectious disease dynamics. …”
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    Inferring Epidemiological Dynamics with Bayesian Coalescent Inference: The Merits of Deterministic and Stochastic Models
  5. 5
    “…In summary, when using genetic data to estimate epidemic dynamics, our results suggest that the birth-death method will be less sensitive to population fluctuations of early outbreaks than the coalescent method that assumes a deterministic exponentially growing infected population.…”
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    Inference of Epidemiological Dynamics Based on Simulated Phylogenies Using Birth-Death and Coalescent Models
  6. 6
    “…The multi-type birth–death model with sampling is a phylodynamic model which enables the quantification of past population dynamics in structured populations based on phylogenetic trees. …”
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    Robust Phylodynamic Analysis of Genetic Sequencing Data from Structured Populations
  7. 7
    “…Detailed information on the interaction of host population dynamics and evolutionary history can inform decisions on how to contain or entirely avoid disease outbreaks. …”
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    Simultaneous reconstruction of evolutionary history and epidemiological dynamics from viral sequences with the birth–death SIR model
  8. 8
    “…We analyze a global human influenza H3N2 virus data set from a geographically structured host population to demonstrate how seasonal dynamics can be inferred simultaneously with the phylogeny and migration process. …”
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    Phylodynamics with Migration: A Computational Framework to Quantify Population Structure from Genomic Data
  9. 9
    “…Population dynamics can be inferred from genetic sequence data by using phylodynamic methods. …”
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    Inferring time-dependent migration and coalescence patterns from genetic sequence and predictor data in structured populations
  10. 10
    “…By comparing our results with population-based surveillance data, we show that we can reliably estimate incidence from viral phylogenies once viral movement in and out of the local population is accounted for. …”
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    Tracking external introductions of HIV using phylodynamics reveals a major source of infections in rural KwaZulu-Natal, South Africa
  11. 11
    “…Bayesian phylogenetics aims at estimating phylogenetic trees together with evolutionary and population dynamic parameters based on genetic sequences. …”
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    Impact of the tree prior on estimating clock rates during epidemic outbreaks
  12. 12
    “…The dataset is too small to show a particular population structure with high significance, however our preliminary analyses suggest that half the population is spreading the virus with an R0 well above 2, while the other half of the population is spreading with an R0 below 1. …”
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    Insights into the Early Epidemic Spread of Ebola in Sierra Leone Provided by Viral Sequence Data
  13. 13
    “…Infecting large portions of the global population, seasonal influenza is a major burden on societies around the globe. …”
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    Characterising the epidemic spread of influenza A/H3N2 within a city through phylogenetics
  14. 14
    “…Modern phylodynamic methods interpret an inferred phylogenetic tree as a partial transmission chain providing information about the dynamic process of transmission and removal (where removal may be due to recovery, death, or behavior change). …”
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    Estimating Epidemic Incidence and Prevalence from Genomic Data
  15. 15
    “…Taking this heterogeneity into account is necessary to obtain accurate estimates of the underlying population dynamics. We present a new multitype birth–death model (MTBD) that can estimate lineage-specific birth and death rates. …”
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    A Multitype Birth–Death Model for Bayesian Inference of Lineage-Specific Birth and Death Rates
  16. 16
    “…Phylodynamic models are widely used in infectious disease epidemiology to infer the dynamics and structure of pathogen populations. However, these models generally assume that individual hosts contact one another at random, ignoring the fact that many pathogens spread through highly structured contact networks. …”
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    Phylodynamics on local sexual contact networks
  17. 17
    “…In summary, our framework provides additional information on the evolutionary dynamics of traits in pathogen populations and may improve GWAS if pathogen effects are highly phylogenetically correlated amongst individuals in a cohort.…”
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    A Phylogeny-aware GWAS Framework to Correct for Heritable Pathogen Effects on Infectious Disease Traits
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    “…Viral phylogenetic methods contribute to understanding how HIV spreads in populations, and thereby help guide the design of prevention interventions. …”
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    Phylogenetic Tools for Generalized HIV-1 Epidemics: Findings from the PANGEA-HIV Methods Comparison
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