Mostrando 1 - 4 Resultados de 4 Para Buscar '"ITAM"', tiempo de consulta: 0.13s Limitar resultados
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    “…Importantly, we show that genetic disruption of the DAP12/FcRγ–Vav pathway leads to antigen presentation defects that are more profound than in DCs lacking NOX2, suggesting that ITAM signaling also controls cross-presentation in a ROS-independent manner.…”
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    An ITAM-signaling pathway controls cross-presentation of particulate but not soluble antigens in dendritic cells
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    Differential Requirements for Vav Proteins in DAP10- and ITAM-mediated NK Cell Cytotoxicity
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    “…Our study demonstrates that signals emanating from ITAM-containing receptors mediated by Vav family Rho GEFs control the velocity, but not the directionality, of neutrophil migration towards sites of bacterial infection. …”
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    ITAM Signaling by Vav Family Rho Guanine Nucleotide Exchange Factors Regulates Interstitial Transit Rates of Neutrophils In Vivo
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    “…Dap12 and FcRγ, the two transmembrane ITAM-containing signaling adaptors expressed in dendritic cells (DC), are implicated in the regulation of DC function. …”
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    Loss of DAP12 and FcRγ Drives Exaggerated IL-12 Production and CD8(+) T Cell Response by CCR2(+) Mo-DCs
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