“…Subjects with FH in both parents had the highest risk of ESCC and GCC incidence (HR(ESCC) = 1.65, 95%CI: 1.40–1.95; HR(GCC) = 1.42, 95%CI: 1.12–1.81) and deaths (HR(ESCC) = 1.65, 95%CI: 1.38–1.97; HR(GCC) = 1.42, 95%CI: 1.09–1.85). …”
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“…Severe tooth loss increased the risk of GCC mortality. Future studies are needed to confirm these findings.…”
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“…No statistically significant result of the family history effect on the risk of death from GCC or GNCC was found. Sensitivity analysis of 80% of subjects, randomly selected, did not change the results. …”
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“…The primary endpoint was death from esophageal squamous cell carcinoma (ESCC), gastric cardia carcinoma (GCC), and gastric noncardia carcinoma (GNCC). Hazard ratios (HRs) and 95% confidence intervals (95% CIs) were estimated using the Cox proportional hazard model. …”
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“…RESULTS: During the 30‐year follow‐up, a total of 902 UGI cancer deaths occurred, including 541 esophageal squamous cell carcinoma (ESCC) related, 284 gastric cardia carcinoma (GCC) related, and 77 gastric noncardia carcinoma (GNCC) related deaths. …”
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“…RESULTS: During over 30 years of follow-up we identified 654 incident esophageal squamous-cell carcinoma (ESCC) cases and 434 gastric cancer cases which included 88 gastric non-cardia carcinoma (GNCC) and 346 gastric cardia carcinoma (GCC) cases. Relative to normal weight, overweight or obesity were associated with a significantly reduced risk of ESCC (HR 0.69, 95 %CI 0.48–0.98) after multivariate adjustment, including age at baseline, gender, smoking, drinking, family history of cancer, education and consumption of fresh fruit. …”
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