Mostrando 1 - 20 Resultados de 133 Para Buscar '"conservator"', tiempo de consulta: 0.28s Limitar resultados
  1. 1
    “…WDR5 is a highly-conserved nuclear protein that performs multiple scaffolding functions in the context of chromatin. …”
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    WDR5 is a conserved regulator of protein synthesis gene expression
  2. 2
    “…Therefore, our findings provide a framework for evaluating the roles of conserved active-site residues, motifs, and domains in CDs.…”
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    Roles of conserved active site residues in the IscS cysteine desulfurase reaction
  3. 3
    “…Failure of mutant polycystins to localize to cilia abolishes flow-stimulated calcium signaling and causes autosomal dominant polycystic kidney disease. We identify a conserved amino acid sequence, KVHPSST, in the C-terminus of polycystin-1 (PC1) that serves as a ciliary-targeting signal. …”
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    A conserved signal and GTPase complex are required for the ciliary transport of polycystin-1
  4. 4
    por Woo, Xing Yi, Giordano, Jessica, Srivastava, Anuj, Zhao, Zi-Ming, Lloyd, Michael W., de Bruijn, Roebi, Suh, Yun-Suhk, Patidar, Rajesh, Chen, Li, Scherer, Sandra, Bailey, Matthew H., Yang, Chieh-Hsiang, Cortes-Sanchez, Emilio, Xi, Yuanxin, Wang, Jing, Wickramasinghe, Jayamanna, Kossenkov, Andrew V., Rebecca, Vito W., Sun, Hua, Mashl, R. Jay, Davies, Sherri R., Jeon, Ryan, Frech, Christian, Randjelovic, Jelena, Rosains, Jacqueline, Galimi, Francesco, Bertotti, Andrea, Lafferty, Adam, O’Farrell, Alice C., Modave, Elodie, Lambrechts, Diether, ter Brugge, Petra, Serra, Violeta, Marangoni, Elisabetta, El Botty, Rania, Kim, Hyunsoo, Kim, Jong-Il, Yang, Han-Kwang, Lee, Charles, Dean, Dennis A., Davis-Dusenbery, Brandi, Evrard, Yvonne A., Doroshow, James H., Welm, Alana L., Welm, Bryan E., Lewis, Michael T., Fang, Bingliang, Roth, Jack A., Meric-Bernstam, Funda, Herlyn, Meenhard, Davies, Michael A., Ding, Li, Li, Shunqiang, Govindan, Ramaswamy, Isella, Claudio, Moscow, Jeffrey A., Trusolino, Livio, Byrne, Annette T., Jonkers, Jos, Bult, Carol J., Medico, Enzo, Chuang, Jeffrey H.
    Publicado 2021
    “…CNA inferences based on DNA sequencing and microarray data displayed substantially higher resolution and dynamic range than gene expression-based inferences, and they also showed strong CNA conservation from PTs through late-passage PDXs. CNA recurrence analysis of 130 colorectal and breast PT/PDX-early/PDX-late trios confirmed high-resolution CNA retention. …”
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    Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts
  5. 5
    por Woo, Xing Yi, Giordano, Jessica, Srivastava, Anuj, Zhao, Zi-Ming, Lloyd, Michael W., de Bruijn, Roebi, Suh, Yun-Suhk, Patidar, Rajesh, Chen, Li, Scherer, Sandra, Bailey, Matthew H., Yang, Chieh-Hsiang, Cortes-Sanchez, Emilio, Xi, Yuanxin, Wang, Jing, Wickramasinghe, Jayamanna, Kossenkov, Andrew V., Rebecca, Vito W., Sun, Hua, Mashl, R. Jay, Davies, Sherri R., Jeon, Ryan, Frech, Christian, Randjelovic, Jelena, Rosains, Jacqueline, Galimi, Francesco, Bertotti, Andrea, Lafferty, Adam, O’Farrell, Alice C., Modave, Elodie, Lambrechts, Diether, ter Brugge, Petra, Serra, Violeta, Marangoni, Elisabetta, El Botty, Rania, Kim, Hyunsoo, Kim, Jong-Il, Yang, Han-Kwang, Lee, Charles, Dean, Dennis A., Davis-Dusenbery, Brandi, Evrard, Yvonne A., Doroshow, James H., Welm, Alana L., Welm, Bryan E., Lewis, Michael T., Fang, Bingliang, Roth, Jack A., Meric-Bernstam, Funda, Herlyn, Meenhard, Davies, Michael A., Ding, Li, Li, Shunqiang, Govindan, Ramaswamy, Isella, Claudio, Moscow, Jeffrey A., Trusolino, Livio, Byrne, Annette T., Jonkers, Jos, Bult, Carol J., Medico, Enzo, Chuang, Jeffrey H.
    Publicado 2021
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    Author Correction: Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts
  6. 6
    “…Here, we focus on N-MYC amplified neuroblastoma to determine the extent of colocalization between N-MYC and WDR5 on chromatin while also demonstrating that like c-MYC, WDR5 can facilitate the recruitment of N-MYC to conserved WDR5-bound genes. We conclude based on this analysis that N-MYC and WDR5 colocalize invariantly across cell lines at predicted sites of facilitated recruitment associated with protein synthesis genes. …”
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    WDR5 facilitates recruitment of N-MYC to conserved WDR5 gene targets in neuroblastoma cell lines
  7. 7
    “…BACKGROUND: Older patients with end-stage renal disease (ESRD) have experienced diminished quality of life and debilitating symptoms. Conservative management may be a potential treatment option. …”
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    Quality of life, symptoms, and sleep quality of elderly with end-stage renal disease receiving conservative management: a systematic review
  8. 8
    “…Tumors in the central and nipple portion (TCNP) had poor prognosis compared to other peripheral quadrants. The breast-conserving therapy (BCT) is becoming increasingly common worldwide in breast cancer operations. …”
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    Breast-Conserving Therapy Has Better Prognosis for Tumors in the Central and Nipple Portion of Breast Cancer Compared with Mastectomy: A SEER Data-Based Study
  9. 9
    “…We observed that the global potential N cycle changes from a conservative cycle in forests to a less conservative one in grasslands and a leaky one in croplands. …”
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    Expanding agroforestry can increase nitrate retention and mitigate the global impact of a leaky nitrogen cycle in croplands
  10. 10
    “…Finally, we explore the practical implications of our findings for the development of conservation strategies in Cycas. The present study demonstrates the efficiency of RADseq for conservation genomic studies on non-model species with large and complex genomes. …”
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    Genome-Wide Evidence for Complex Hybridization and Demographic History in a Group of Cycas From China
  11. 11
    por Wang, Jing, Chen, Min, Du, Jiang
    Publicado 2017
    “…RATIONALE: Elbow injury in children by improper treatment or a delay of more than 3 weeks could lead to old unreduced Monteggia fracture, which are difficult to manage. Conservative or normal surgical methods usually fail. …”
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    Type III Monteggia fracture with posterior interosseous nerve injury in a child: A case report
  12. 12
    “…Universal primers were used to amplify highly conserved region located within the 16S rRNA amplicon, followed by hybridized to pathogen-specific probes for identification of these five organisms. …”
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    Comparison of Two Suspension Arrays for Simultaneous Detection of Five Biothreat Bacterial in Powder Samples
  13. 13
    “…Here we describe how miR-615-3p represses hTERT expression. mir-615-3p is located in an intron of the HOXC5 gene, a member of the highly conserved homeobox family of transcription factors controlling embryogenesis and development. …”
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    HoxC5 and miR-615-3p target newly evolved genomic regions to repress hTERT and inhibit tumorigenesis
  14. 14
    “…We performed trio medical exome sequencing of the family and conservation analysis to identify variants. RESULTS: We report a pair of severe CNM twins with the same novel homozygous SPEG variant c. 8710A>G (p.Thr2904Ala) identified by clinical trio medical exome sequencing of the family and conservation analysis. …”
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    Novel SPEG variant cause centronuclear myopathy in China
  15. 15
    “…We further identify the most vulnerable populations that need conservation priority and many candidate genes and variants that may be useful for forest tree breeding with special aims. …”
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    Genomic insights into local adaptation and future climate-induced vulnerability of a keystone forest tree in East Asia
  16. 16
    “…Moreover, the genome structure, codon usage, and repeat sequences were highly conserved and showed similarities among the seven species. …”
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    Comparative analysis of medicinal plant Isodon rubescens and its common adulterants based on chloroplast genome sequencing
  17. 17
    por Wang, Jing, Li, Shao-Lei, Wu, Nan, Wu, Qi
    Publicado 2020
    “…In conclusion, the application of conservative electrocoagulation followed by porcine FS as a wound-protection technique promoted ESD-induced ulcer healing in the esophagus. …”
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    Effectiveness of fibrin sealant as a hemostatic technique in accelerating endoscopic submucosal dissection-induced ulcer healing and preventing stricture in the esophagus: A retrospective study
  18. 18
    “…Here, we designed two novel composite immunogens containing highly conserved T-cell epitopes of six influenza A virus internal antigens, and expressed them in DNA, recombinant adenovirus-based (AdC68) and recombinant vaccinia vectors, respectively, to formulate three vaccine forms. …”
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    Influenza Vaccine With Consensus Internal Antigens as Immunogens Provides Cross-Group Protection Against Influenza A Viruses
  19. 19
    “…All patients received the traditional conservative treatments of debridement of the necrotic tissues guided by an endoscope and systematic antibiotic therapy partly guided by culture results. …”
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    Retrospective Analysis of a Modified Irrigation Method for Nasopharyngeal Carcinoma Patients With Post-Radiation Nasopharyngeal Necrosis
  20. 20
    “…Monocot ARGs have more conserved mitochondrion-targeting signals and are more evolutionarily conserved than dicot ARGs.…”
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    Comprehensive molecular analysis of arginase-encoding genes in common wheat and its progenitor species
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