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1por Dai, Zhuozhi, Ji, Jim, Xiao, Gang, Yan, Gen, Li, Shengkai, Zhang, Guishan, Lin, Yan, Shen, Zhiwei, Wu, Renhua“…Chemical exchange saturation transfer (CEST) is an emerging MRI contrast mechanism that is capable of noninvasively imaging dilute CEST agents and local properties such as pH and temperature, augmenting the routine MRI methods. …”
Publicado 2014
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2por Tang, Yanyan, Xiao, Gang, Shen, Zhiwei, Zhuang, Caiyu, Xie, Yudan, Zhang, Xiaolei, Yang, Zhongxian, Guan, Jitian, Shen, Yuanyu, Chen, Yanzi, Lai, Lihua, Chen, Yuanfeng, Chen, Shuo, Dai, Zhuozhi, Wang, Runrun, Wu, Renhua“…RESULTS: By conducting dual-power CEST MRI, the pH of solutions was determined to be 6.0–7.2 at 3T in vitro. …”
Publicado 2020
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3por Chen, Miaomiao, Chen, Chaoying, Shen, Zhiwei, Zhang, Xiaolei, Chen, Yanzi, Lin, Fengfeng, Ma, Xilun, Zhuang, Caiyu, Mao, Yifei, Gan, Haochuan, Chen, Peidong, Zong, Xiaodan, Wu, Renhua“…Extracellular pH (pH(e)) decrease is associated with tumor growth, invasion, metastasis, and chemoresistance, which can be detected by chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI). Here, we demonstrated that ioversol CEST MRI can be exploited to achieve pH(e) mapping of the liver cancer microenvironment. …”
Publicado 2017
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4por Jia, Yanlong, Chen, Yanzi, Geng, Kuan, Cheng, Yan, Li, Yan, Qiu, Jinming, Huang, Huaidong, Wang, Runrun, Zhang, Yunping, Wu, Renhua“…Hence, using glutamate chemical exchange saturation transfer (GluCEST) imaging for the early diagnosis of encephalitis holds promise. …”
Publicado 2020
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5por Yan, Gen, Zhang, Tao, Dai, Zhuozhi, Yi, Meizhi, Jia, Yanlong, Nie, Tingting, Zhang, Handi, Xiao, Gang, Wu, Renhua“…PURPOSE: We developed a novel magnetic resonance imaging (MRI) technique based on chemical exchange saturation transfer (CEST) for GABA imaging and investigated the concentration-dependent CEST effect ofGABA in a rat model of brain tumor with blood—brain barrier (BBB) disruption. …”
Publicado 2016
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6“…METHODS: A total of 20 patients with BD, 30 with UD patients, and 20 matched healthy controls (HCs) underwent 3.0T magnetic resonance imaging with chemical exchange saturation transfer (CEST) for glutamate (Glu; GluCEST) imaging, multivoxel magnetic resonance spectroscopy, and diffusion kurtosis imaging. …”
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7por Chen, Peidong, Shen, Zhiwei, Wang, Qianqian, Zhang, Bingna, Zhuang, Zerui, Lin, Jiefen, Shen, Yuanyu, Chen, Yanzhi, Dai, Zhuozhi, Wu, Renhua“…In addition, there is a significant positive correlation between glucoCEST enhancement (GCE) and myo-Inosito (Ins) in the AD group and the control group (P < 0.05). …”
Publicado 2021
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8por Jia, Yanlong, Wang, Chaochao, Zheng, Jiehua, Lin, Guisen, Ni, Dalong, Shen, Zhiwei, Huang, Baoxuan, Li, Yan, Guan, Jitian, Hong, Weida, Chen, Yuanfeng, Wu, Renhua“…The PEG-b-P(AM-co-AN) has chemical exchange saturation transfer (CEST) effects, which enable the use of CEST imaging for monitoring nanocarrier accumulation and providing molecular information of pathological tissues. …”
Publicado 2019
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9“…Recently, nanotheranostic agents that combine medicinal drugs and chemical exchange saturated transfer (CEST) contrast agents have shown good promise because CEST imaging technology can utilize the frequency-selective radiofrequency pulse from exchangeable protons to indirectly image without requiring metals or radioactive agents. …”
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