“…The clinical diagnosis of Parkinson's disease (PD) is very difficult, especially in the early stage of the disease, because there is no physiological indicator that can be referenced. Drug-free patients with early PD are characterized by clinical symptoms such as impaired motor function and cognitive decline, which was caused by the dysfunction of brain's dynamic activities. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The main objective of this study was to determine the predictive value of US characteristics for disease-free survival (DFS) in BC patients. We retrospectively analyzed the ultrasonic images and clinical data of BC patients who had previously undergone breast surgery at least 10 years before study enrollment and divided them into a case group and a control group according to the cutoff value of 120 months for DFS. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Hybridbio/‐synthetic sensory conjugated polymer nanoparticles (CPNs) are developed for selective label‐free detection of target ssDNA in serum. Carboxylic acid‐functionalized anionic polyfluorene nanoparticles are rationally designed as signal amplifying unit to bioconjugate with amine functionalized single stranded oligonucleotides as a receptor. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In order to study the effect of meso-iodination of free-base corroles on their photophysical character, we designed and synthesized a series of free-base corrole derivatives F10–OH (iodine-free), F10–OH–I (mono-iodo) and F10–OH–2I (di-iodo), with different substitution patterns at the meso-position as candidates for photodynamic therapy (PDT). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Here, we report a highly continuous and completely gap-free reference genome of Actinidia chinensis cv. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Two patients in the UCBT group relapsed, two died of acute and chronic GVHD, and one patient developed chronic GVHD 140 days after UCBT and is still alive, so the GVHD-free/relapse-free survival (GRFS) was 50% (95% CI, 17.2–76.1%). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…However, because of a lack of appropriate data, limited research has been conducted on variations in disability-free life expectancy (DFLE) among older adults. This study aimed to use the most up-to-date disability survey data to explore geographical variations in DFLE at age 60 in China and to identify the socioeconomic and health care factors that partially account for these variations. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…However, certain advantageous properties usually associated with the liquid state of matter, such as processability, flowability, or molecular mobility, are highly sought-after features for biomacromolecules in a solvent-free environment. Here, we provide an overview over the design principles and synthetic pathways to obtain solvent-free liquids of biomacromolecular architectures approaching the topic from our own perspective of research. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The serial monitoring of tumor genotypes is becoming increasingly attainable with circulating cell-free DNA (cf-DNA) and circulating tumor cells (CTCs) emerging as “liquid biopsies”. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Here, we have proposed and experimentally demonstrated a calibration-free sensor for achieving high-precision biosensing detection, based on an optically controlled terahertz (THz) ultrafast metasurface. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Molecular models of lipid-free apo A-I have been reported by methods like X-ray crystallography and chemical cross-linking/mass spectrometry (CCL/MS). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This approach, when combined with real-time label-free Raman spectroscopy of biochemical composition changes and confocal light scattering spectroscopic microscopy of chromatin transition, allows for monitoring live differentiating organoids without the need to sacrifice a sample, substantially shortening the time of protocol fine-tuning. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Here we report beat frequency (BF) QEPAS that can be used for ultra-sensitive calibration-free trace-gas detection and fast spectral scan applications. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

Enlace del recurso
Enlace del recurso
Enlace del recurso

“…METHODS: We utilized 5hmC-Seal to profile genome-wide 5-hydroxymethylcytosines in plasma cell-free DNA (cfDNA). Candidate genes were identified by intersecting the differentially hydroxymethylated genes and differentially expressed genes from the GSE30528 and GSE30529. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…There was no significant difference between the two cohorts in terms of transplant-related mortality (TRM), relapse, and long-term survival (overall survival and leukemia-free survival). The 5-year probability of GVHD-free/relapse-free survival (GRFS) was 47.9% and 33.4% in the CBT and the sibling-PBSCT/BMT cohorts, respectively (p = 0.632); among patients who survived more than 100 days after transplantation (n = 61), the 5-year probability of chronic GVHD-free, relapse-free survival (CRFS) was 66.2% in the CBT cohort, which was significantly higher than that in the sibling-PBSCT/BMT cohort (37.4%) (p = 0.037). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In this study, a new metal-free photoinduced electron transfer-reversible addition-fragmentation chain transfer (PET-RAFT) polymerization system was developed for controlled macromolecular synthesis in both heterogeneous and homogeneous systems by structural engineering of graphitic carbon nitrides (g-C(3)N(4)) to improve the textural, optical, and electronic properties. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This work opens a new window of opportunity for DMSO-free MSC cryopreservation using zwitterionic compounds like betaine combined with electroporation.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso