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21por Dian, Sofiati, Hermawan, Robby, van Laarhoven, Arjan, Immaculata, Sofia, Achmad, Tri Hanggono, Ruslami, Rovina, Anwary, Farhan, Soetikno, Ristaniah D., Ganiem, Ahmad Rizal, van Crevel, Reinout“…We performed magnetic resonance imaging (MRI) at baseline and after two months treatment to characterise neuroradiological patterns in a prospective cohort of adult TBM patients in Indonesia. We included 48 TBM patients (median age 30, 52% female, 8% HIV-infected), most of whom had grade II (90%), bacteriologically confirmed (71%) disease, without antituberculotic resistance. …”
Publicado 2020
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22por Png, Eileen, Alisjahbana, Bachti, Sahiratmadja, Edhyana, Marzuki, Sangkot, Nelwan, Ron, Balabanova, Yanina, Nikolayevskyy, Vladyslav, Drobniewski, Francis, Nejentsev, Sergey, Adnan, Iskandar, van de Vosse, Esther, Hibberd, Martin L, van Crevel, Reinout, Ottenhoff, Tom HM, Seielstad, Mark“…In order to identify additional targets in genetically dissimilar populations, and to enhance our understanding of this disease, we performed a multi-stage GWAS in a Southeast Asian cohort from Indonesia. METHODS: In stage 1, we used the Affymetrix 100 K SNP GeneChip marker set to genotype 259 Indonesian samples. …”
Publicado 2012
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23por Meijerink, Hinta, Indrati, Agnes, Utami, Fitri, Soedarmo, Suharyani, Alisjahbana, Bachti, Netea, Mihai G., van Crevel, Reinout, Wisaksana, Rudi, van der Ven, Andre Jam“…METHODS: Treatment naïve HIV-infected individuals from Indonesia were recruited. Several cohorts of individuals were recruited: 1) using heroin 2) receiving methadone opioid substitution 3) using heroin over 1 year ago and 4) controls (never used opioids). …”
Publicado 2015
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24por Heemskerk, A. Dorothee, Donovan, Joseph, Thu, Do Dang Anh, Marais, Suzaan, Chaidir, Lidya, Dung, Vu Thi Mong, Centner, Chad M., Ha, Vu Thi Ngoc, Annisa, Jessi, Dian, Sofiati, Bovijn, Louise, Mai, Nguyen Thi Hoang, Phu, Nguyen Hoan, Chau, Nguyen Van Vinh, Ganiem, Ahmad Rizal, Van, Cao Thao, Geskus, Ronald B., Thuong, Nguyen Thuy Thuong, Ruslami, Rovina, Meintjes, Graeme, van Crevel, Reinout, Wilkinson, Robert J., Thwaites, Guy E.“…METHODS: In hospitals in Vietnam, South Africa and Indonesia we conducted a prospective study of modified ZN with or without cytospin, conventional ZN smear, GeneXpert, and culture on CSF in adults with suspected TBM. …”
Publicado 2018
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25por Davila, Sonia, Hibberd, Martin L., Hari Dass, Ranjeeta, Wong, Hazel E. E., Sahiratmadja, Edhyana, Bonnard, Carine, Alisjahbana, Bachti, Szeszko, Jeffrey S., Balabanova, Yanina, Drobniewski, Francis, van Crevel, Reinout, van de Vosse, Esther, Nejentsev, Sergey, Ottenhoff, Tom H. M., Seielstad, Mark“…Initially, we genotyped 149 sequence polymorphisms in 375 pulmonary TB patients and 387 controls from Indonesia. We found that four polymorphisms in the TLR8 gene on chromosome X showed evidence of association with TB susceptibility in males, including a non-synonymous polymorphism rs3764880 (Met1Val; P = 0.007, odds ratio (OR) = 1.8, 95% c.i. = 1.2–2.7). …”
Publicado 2008
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26por Vrieling, Frank, Alisjahbana, Bachti, Sahiratmadja, Edhyana, van Crevel, Reinout, Harms, Amy C., Hankemeier, Thomas, Ottenhoff, Tom H. M., Joosten, Simone A.“…Targeted tandem liquid chromatography–mass spectrometry (LC-MS/MS) was used to compare amine and acylcarnitine levels in plasma samples of patients with TB or TB-DM from Indonesia at time of diagnosis and during antibiotic treatment. …”
Publicado 2019
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27por Wisaksana, Rudi, de Mast, Quirijn, Alisjahbana, Bachti, Jusuf, Hadi, Sudjana, Primal, Indrati, Agnes R., Sumantri, Rachmat, Swinkels, Dorine, van Crevel, Reinout, van der Ven, Andre“…METHODS: Three groups of patients were selected from a prospective cohort of HIV-infected subjects in Bandung, Indonesia. The first group consisted of HIV-infected patients who started TB treatment more than 30 days after cohort enrollment (cases). …”
Publicado 2013
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28por Eckold, Clare, Kumar, Vinod, Weiner, January, Alisjahbana, Bachti, Riza, Anca-Lelia, Ronacher, Katharina, Coronel, Jorge, Kerry-Barnard, Sarah, Malherbe, Stephanus T, Kleynhans, Leanie, Stanley, Kim, Ruslami, Rovina, Ioana, Mihai, Ugarte-Gil, Cesar, Walzl, Gerhard, van Crevel, Reinout, Wijmenga, Cisca, Critchley, Julia A, Dockrell, Hazel M, Cliff, Jacqueline M“…METHODS: Whole blood samples were collected from active TB patients with diabetes (glycated hemoglobin [HbA1c] ≥6.5%) or IH (HbA1c = 5.7% to <6.5%), TB-only patients, and healthy controls in 4 countries: South Africa, Romania, Indonesia, and Peru. Differential blood gene expression was determined by RNA-seq (n = 249). …”
Publicado 2020
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29por Ruesen, Carolien, Chaidir, Lidya, van Laarhoven, Arjan, Dian, Sofiati, Ganiem, Ahmad Rizal, Nebenzahl-Guimaraes, Hanna, Huynen, Martijn A., Alisjahbana, Bachti, Dutilh, Bas E., van Crevel, Reinout“…METHODS: We whole-genome sequenced M. tuberculosis strains isolated from 322 HIV-negative tuberculosis patients from Indonesia and compared isolates from patients with TBM (n = 106) and PTB (n = 216). …”
Publicado 2018
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30por Donovan, Joseph, Phu, Nguyen Hoan, Mai, Nguyen Thi Hoang, Dung, Le Tien, Imran, Darma, Burhan, Erlina, Ngoc, Lam Hong Bao, Bang, Nguyen Duc, Giang, Do Chau, Ha, Dang Thi Minh, Day, Jeremy, Thao, Le Thi Phuong, Thuong, Nguyen TT, Vien, Nguyen Nang, Geskus, Ronald B., Wolbers, Marcel, Hamers, Raph L, van Crevel, Reinout, Nursaya, Mugi, Maharani, Kartika, Hien, Tran Tinh, Baird, Kevin, Lan, Nguyen Huu, Kestelyn, Evelyne, Chau, Nguyen Van Vinh, Thwaites, Guy E.“…The trial will be set in two hospitals in Ho Chi Minh City, Vietnam, and two hospitals in Jakarta, Indonesia. The trial will enrol 520 HIV-infected adults. …”
Publicado 2018
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31por van Doorn, Cassandra L.R., Eckold, Clare, Ronacher, Katharina, Ruslami, Rovina, van Veen, Suzanne, Lee, Ji-Sook, Kumar, Vinod, Kerry-Barnard, Sarah, Malherbe, Stephanus T., Kleynhans, Léanie, Stanley, Kim, Hill, Philip C., Joosten, Simone A., van Crevel, Reinout, Wijmenga, Cisca, Critchley, Julia A., Walzl, Gerhard, Alisjahbana, Bachti, Haks, Mariëlle C., Dockrell, Hazel M., Ottenhoff, Tom H.M., Vianello, Eleonora, Cliff, Jacqueline M.“…METHODS: Samples were collected in a longitudinal cohort study of adult TB patients from South Africa (n = 94) and Indonesia (n = 81), who had concomitant DM (n = 59), intermediate hyperglycaemia (n = 79) or normal glycaemia/no DM (n = 37). …”
Publicado 2022
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32Impaired resolution of blood transcriptomes through tuberculosis treatment with diabetes comorbiditypor Eckold, Clare, van Doorn, Cassandra L. R., Ruslami, Rovina, Ronacher, Katharina, Riza, Anca‐Lelia, van Veen, Suzanne, Lee, Ji‐Sook, Kumar, Vinod, Kerry‐Barnard, Sarah, Malherbe, Stephanus T., Kleynhans, Léanie, Stanley, Kim, Joosten, Simone A., Critchley, Julia A, Hill, Philip C., van Crevel, Reinout, Wijmenga, Cisca, Haks, Mariëlle C., Ioana, Mihai, Alisjahbana, Bachti, Walzl, Gerhard, Ottenhoff, Tom H. M., Dockrell, Hazel M., Vianello, Eleonora, Cliff, Jacqueline M.“…METHODS: Pulmonary TB patients recruited in South Africa, Indonesia and Romania were classified as having TB‐DM, TB with prediabetes, TB‐related hyperglycaemia or TB‐only, based on glycated haemoglobin concentration at TB diagnosis and after 6 months of TB treatment. …”
Publicado 2023
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33por Marais, Suzaan, Cresswell, Fiona V, Hamers, Raph L., te Brake, Lindsey H.M., Ganiem, Ahmad R., Imran, Darma, Bangdiwala, Ananta, Martyn, Emily, Kasibante, John, Kagimu, Enock, Musubire, Abdu, Maharani, Kartika, Estiasari, Riwanti, Kusumaningrum, Ardiana, Kusumadjayanti, Nadytia, Yunivita, Vycke, Naidoo, Kogieleum, Lessells, Richard, Moosa, Yunus, Svensson, Elin M., Huppler Hullsiek, Katherine, Aarnoutse, Rob E., Boulware, David R., van Crevel, Reinout, Ruslami, Rovina, Meya, David B.“…The trial will be conducted across five clinical sites in Uganda, South Africa and Indonesia. Participants are HIV-positive or negative adults with clinically suspected TBM, who will be randomised (1:1) to one of two arms: 35 mg/kg oral rifampicin daily for 8 weeks (in combination with standard dose isoniazid [H], pyrazinamide [Z] and ethambutol [E]) or standard of care (oral HRZE, containing 10 mg/kg/day rifampicin). …”
Publicado 2020
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