Mostrando 1 - 20 Resultados de 191 Para Buscar '"ITAM"', tiempo de consulta: 0.21s Limitar resultados
  1. 1
    “…Immune cells express receptors bearing an immune tyrosine activation motif (ITAM) containing two YXXL motifs or hemITAMs containing only one YXXL motif. …”
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    Phosphorylation on Syk Y342 is important for both ITAM and hemITAM signaling in platelets
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    por Zhao, Baohong
    Publicado 2015
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    RBP-J and ITAM crosstalk
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    “…Most TCR ITAMs (6 of 10) are contributed by the CD3ζ subunits. …”
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    TCR ITAM multiplicity is required for the generation of follicular helper T-cells
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    “…Collagen activates mammalian platelets through a complex of the immunoglobulin (Ig) receptor GPVI and the Fc receptor γ-chain, which has an immunoreceptor tyrosine-based activation motif (ITAM). Cross-linking of GPVI mediates activation through the sequential activation of Src and Syk family kinases and activation of PLCγ2. …”
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    G6f-Like Is an ITAM-Containing Collagen Receptor in Thrombocytes
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    Selection and characterization of FcϵRI phospho-ITAM specific antibodies
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    RBP-J imposes a requirement for ITAM-mediated costimulation of osteoclastogenesis
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    “…Several activating NK cell receptors are coupled to adaptor molecules containing an immunoreceptor tyrosine-based activation motif (ITAM). These receptors include CD16 and the natural cytotoxic receptors NKp46, NKp44, NKp30 in humans. …”
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    Role of the ITAM-Bearing Receptors Expressed by Natural Killer Cells in Cancer
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    “…This phosphorylation induces the recruitment of spleen tyrosine kinase (Syk), which is required for downstream NF-κB activation, indicating that the tetherin cytoplasmic tail resembles the hemi-immunoreceptor tyrosine-based activation motifs (hemITAMs) found in C-type lectin pattern recognition receptors. …”
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    Retroviral Retention Activates a Syk-Dependent HemITAM in Human Tetherin
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    “…The current study presents initial validation statistics for the Italian Mood Scale (ITAMS), a culturally- and linguistically-validated Italian version of the Brunel Mood Scale (BRUMS: Terry and Lane, 2010). …”
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    Development and Initial Validation of the Italian Mood Scale (ITAMS) for Use in Sport and Exercise Contexts
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    “…The ITAM-bearing transmembrane signaling subunits (TSS) are indispensable components of activating leukocyte receptor complexes. …”
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    Retention of duplicated ITAM-containing transmembrane signaling subunits in the tetraploid amphibian species Xenopus laevis
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    “…In this study, the in vivo functions of FcRγ ITAM tyrosines were characterized using wild type and ITAM tyrosine mutant (Y65F/Y76F) transgenic mice crossed to an FcRγ-deficient genetic background. …”
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    Importance of Fc Receptor γ-Chain ITAM Tyrosines in Neutrophil Activation and in vivo Autoimmune Arthritis
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    Phosphorylation of spleen tyrosine kinase at Y346 negatively regulates ITAM-mediated signaling and function in platelets
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    Partially Defective Store Operated Calcium Entry and Hem(ITAM) Signaling in Platelets of Serotonin Transporter Deficient Mice
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    “…INTRODUCTION: The immunoreceptor tyrosine-based activation motif (ITAM) pathway provides osteoclast co-stimulatory signals and regulates proliferation, survival and differentiation of effector immune cells. …”
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    The immunoreceptor tyrosine-based activation motif (ITAM) -related factors are increased in synovial tissue and vasculature of rheumatoid arthritic joints
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    “…Our research investigates how institutions influence the adoption of new IT by using the Institution-based Technology Acceptance Model (ITAM). We conducted an empirical test by using survey data collected from 300 employees in the public sector. …”
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    Searching for New Model of Digital Informatics for Human–Computer Interaction: Testing the Institution-Based Technology Acceptance Model (ITAM)
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    “…Antiplatelet drugs targeting G-protein-coupled receptors (GPCRs), used for the secondary prevention of arterial thrombosis, coincide with an increased bleeding risk. Targeting ITAM-linked receptors, such as the collagen receptor glycoprotein VI (GPVI), is expected to provide a better antithrombotic-hemostatic profile. …”
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    Ultra-high-throughput Ca(2+) assay in platelets to distinguish ITAM-linked and G-protein-coupled receptor activation
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    “…FCER1G is a component of Fc receptor complexes that contain an immunoreceptor tyrosine-based activation motif (ITAM). SYK interacts with the Fc receptor by binding to doubly phosphorylated ITAM (p-ITAM) via its two tandem SH2 domains (SYK-tSH2). …”
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    Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM
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    “…Our results reveal that MHC-I molecules display specific patterns of “selective” inhibition over cytotoxicity and cytokine production induced by ITAM-dependent receptors and 2B4, but not on NKG2D. …”
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    MHC-I Molecules Selectively Inhibit Cell-Mediated Cytotoxicity Triggered by ITAM-Coupled Activating Receptors and 2B4
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    por Neeves, Keith B.
    Publicado 2021
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    A tail of two ITAMs: GPVI/FcRγ and FcγRIIa's role in platelet activation and thrombus stability
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    “…We also demonstrate that various ITAM associated activation receptors, including Ly49H, remain associated with their respective adaptor molecules. …”
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    Chronic Ly49H Receptor Engagement in vivo Decreases NK Cell Response to Stimulation Through ITAM-Dependent and Independent Pathways Both in vitro and in vivo
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