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61por Maia, Eduardo H. B., Medaglia, Lucas Rolim, da Silva, Alisson Marques, Taranto, Alex G.“…This context has motivated us to develop Molecular Architect (MolAr). MolAr is a workflow with a simple and intuitive interface that acts in an integrated and automated form to perform the entire VS process, from protein preparation (homology modeling and protonation state) to virtual screening. …”
Publicado 2020
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62por Liu, Siying, Wang, Wenbo, Xu, Weiheng, Liu, Luyang, Zhang, Wenlong, Song, Kenan, Chen, Xiangfan“…Additive manufacturing (AM), also known as three-dimensional (3D) printing, is thriving as an effective and robust method in fabricating architected piezoelectric structures, yet most of the commonly adopted printing techniques often face the inherent speed-accuracy trade-off, limiting their speed in manufacturing sophisticated parts containing micro-/nanoscale features. …”
Publicado 2022
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63por Saccone, Max A., Gallivan, Rebecca A., Narita, Kai, Yee, Daryl W., Greer, Julia R.“…We report an AM technique that produces metals and alloys with microscale resolution via vat photopolymerization (VP). Three-dimensional-architected hydrogels are infused with metal precursors, then calcined and reduced to convert the hydrogel scaffolds into miniaturized metal replicas. …”
Publicado 2022
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64por Pérez de Isla, Leopoldo, Díaz-Díaz, Jose L., Romero, Manuel J., Muñiz-Grijalvo, Ovidio, Mediavilla, Juan D., Argüeso, Rosa, Sánchez Muñoz-Torrero, Juan F., Rubio, Patricia, Álvarez-Baños, Pilar, Ponte, Paola, Mañas, Dolores, Suárez Gutierrez, Lorena, Cepeda, José María, Casañas, Marta, Fuentes, Francisco, Guijarro, Carlos, Ángel Barba, Miguel, Saltijeral Cerezo, Adriana, Padró, Teresa, Mata, Pedro“…CONCLUSIONS: Treatment with alirocumab in addition to high-intensity statin therapy resulted in significant regression of coronary plaque burden and plaque stabilization on coronary computed tomographic angiography over 78 weeks in these groups of patients with familial hypercholesterolemia without clinical atherosclerotic cardiovascular disease. ARCHITECT (Effect of Alirocumab on Atherosclerotic Plaque Volume, Architecture and Composition) could link and explain ODYSSEY OUTCOMES (Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab) results. …”
Publicado 2023
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65por Libonati, Flavia, Graziosi, Serena, Ballo, Federico, Mognato, Marco, Sala, Giacomo“…By looking ahead, mimicking the characteristic microscale structure of crystalline materials will allow replicating the typical behavior of crystals at a larger scale, combining the hardening traits of metallurgy with the characteristic behavior of polymers and the advantage of lightweight architected structures, leading to novel materials with multiple functions.…”
Publicado 2021
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67por Peng, Bo, Wei, Ye, Qin, Yu, Dai, Jiabao, Li, Yue, Liu, Aobo, Tian, Yun, Han, Liuliu, Zheng, Yufeng, Wen, Peng“…Architected materials that consist of multiple subelements arranged in particular orders can demonstrate a much broader range of properties than their constituent materials. …”
Publicado 2023
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71“…This experimental and computational work demonstrates that the discrete-continuum duality of architected structural meta-materials may give rise to their damage tolerance and insensitivity of failure to the presence of flaws even when made entirely of intrinsically brittle materials.…”
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72“…METHODS: Determination of between-run precision, and Deming comparison between patient sample results for 25OHD on the Abbott Architect, DiaSorin Liaison and AB SCIEX API 4000 (LC-MS/MS). …”
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73“…In this article, we present 11 quick tips for architecting biomedical informatics workflows on compute clouds, distilling knowledge gained from experience developing, operating, maintaining, and distributing software and virtualized appliances on the world’s largest cloud. …”
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74por Cheng, Kevin, Coller, Kelly E., Marohnic, Christopher C., Pfeiffer, Zachary A., Fino, James R., Elsing, Randee R., Bergsma, Janet, Marcinkus, Marilee A., Kar, Alak K., Gumbs, Orlando H., Otis, Kathy S., Fishpaugh, Jeffrey, Schultz, Phillip W., Pope, Mark R., Narvaez, Alfredo R., Wong, Susan J., Madison-Antenucci, Susan, Leary, Thomas P., Dawson, George J.“…A fully automated prototype B. microti antibody test was developed on the Architect instrument. The specificity was determined to be 99.98% in volunteer blood donors (n = 28,740) from areas considered to have low endemicity for B. microti. …”
Publicado 2018
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75por Soh, A., Binder, L., Clough, M., Hernandez, M. Hernandez, Lefèvre, G., Mostert, K., Nguyen, T.B., Otte, K.-M., Portakal, O., Sandri, M.S., Yen, J.L., Huang, J., Beshiri, A.“…AIMS: This study assessed the performance of a new fully automated immunoassay, ARCHITECT B.R.A.H.M.S procalcitonin (PCT), comparing the results with other commercial assays on routine clinical specimens. …”
Publicado 2018
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77por Zyrianoff, Ivan, Heideker, Alexandre, Silva, Dener, Kleinschmidt, João, Soininen, Juha-Pekka, Salmon Cinotti, Tullio, Kamienski, CarlosEnlace del recurso
Publicado 2019
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78por Thorudottir, Sandra, Sigurdardottir, Heida M., Rice, Grace E., Kerry, Sheila J., Robotham, Ro J., Leff, Alex P., Starrfelt, Randi“…Here we report neuropsychological data from an architect (PL518) who lost his ability for visual imagery following a bilateral posterior cerebral artery (PCA) stroke. …”
Publicado 2020
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80“…A model-based approach to large-scale distributed system architecting is suggested, which is based on the use of dynamic digital twins. …”
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