Mostrando 1 - 20 Resultados de 963 Para Buscar 'Arcueil~', tiempo de consulta: 2.71s Limitar resultados
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    por Merkl, Rainer
    Publicado 2007
    “…RESULTS: In order to study the evolution of trp genes, completely sequenced archeal and bacterial genomes containing trpB were analysed. …”
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    “…To structurally analyse these channels, we selected nanobodies against an archeal MS channel after immunization of a llama with recombinant expressed, detergent solubilized and purified protein. …”
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    por Ribas de Pouplana, Lluís
    Publicado 2022
    “…This field is in constant evolution driven by the discovery or design of new tools, many of which are based on archeal biology. In a recent article published in JBC, one such tool is characterized and its evolution studied, revealing unexpected details regarding the emergence of the universal genetic code machinery.…”
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    “…Here, we report an approach that exploits protein engineering to “humanise” thermophilic archeal surrogate proteins as targets for small-molecule inhibitor discovery and to exemplify this approach in the development of inhibitors against the PPI between the recombinase RAD51 and tumour suppressor BRCA2. …”
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