Mostrando 1 - 20 Resultados de 25 Para Buscar '"whig"', tiempo de consulta: 0.06s Limitar resultados
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    “…Here we demonstrate that c-di-GMP also intervenes later in development to control differentiation of the reproductive hyphae into spores by arming a novel anti-σ (RsiG) to bind and sequester a sporulation-specific σ factor (σ(WhiG)). We present the structure of the RsiG-(c-di-GMP)(2)-σ(WhiG) complex, revealing an unusual, partially intercalated c-di-GMP dimer bound at the RsiG-σ(WhiG) interface. …”
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  14. 14
    por Kaiser, Brett K., Stoddard, Barry L.
    Publicado 2011
    “…WhiA transcription is stimulated by WhiG, while the WhiA protein binds directly to WhiG (leading to inhibition of WhiG-dependent transcription). …”
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  15. 15
    “…We recently showed c-di-GMP controls this transition by arming a unique anti-σ, RsiG, to bind the sporulation-specific σ, WhiG. The Streptomyces venezuelae RsiG–(c-di-GMP)(2)–WhiG structure revealed that a monomeric RsiG binds c-di-GMP via two E(X)(3)S(X)(2)R(X)(3)Q(X)(3)D repeat motifs, one on each helix of an antiparallel coiled-coil. …”
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  16. 16
    “…Here we show that whi-independent expression of FtsZ restores sporulation to the early sporulation mutants whiA, whiB, whiG, whiH, whiI and whiJ. Viability, stress resistance and high-resolution electron microscopy underlined that viable spores were formed. …”
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  17. 17
    por Laws, Keith R.
    Publicado 2016
    “…The issue of reproducibility occupies a central place in our whig history of psychology.…”
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  18. 18
    “…Expression of one sRNA in particular was dependent upon the sporulation-specific sigma factor σ(WhiG).…”
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    “…Detected by quantitative real-time PCR, the relative transcription of SACE_7115, the amfC homolog for an aerial mycelium formation protein, was dramatically increased in SACE_0012 mutant, whereas erythromycin biosynthetic gene eryA, a pleiotropic regulatory gene bldD, and the genes SACE_2141, SACE_6464, SACE_6040, that are the homologs to the sporulation regulators WhiA, WhiB, WhiG, were not differentially expressed. SACE_0012 disruption could not restore its defect of aerial development in bldD mutant, and also did not further accelerate the mycelium formation in the mutant of SACE_7040 gene, that was previously identified to be a morphogenesis repressor. …”
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  20. 20
    “…In contrast, Group II genes were expressed later than Group I genes and their expression depended not only on bldM but also on whiI and whiG (encoding the sigma factor that activates whiI). …”
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