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1ARCHITECT HIV Combo Ag/Ab and RealTime HIV-1 Assays Detect Diverse HIV Strains in Clinical SpecimensBằng Rodgers, Mary A., Vallari, Ana S., Yamaguchi, Julie, Holzmayer, Vera, Harris, Barbara, Toure-Kane, Coumba, Mboup, Souleymane, Badreddine, Samar, McArthur, Carole, Ndembi, Nicaise, Mbanya, Dora, Kaptue, Lazare, Cloherty, Gavin“…To determine whether HIV diversity impacts the ARCHITECT HIV Combo Ag/Ab (HIV Combo) or RealTime HIV-1 (RT) assays, a set of N = 199 HIV clinical specimens from Cameroon, Senegal, Saudi Arabia, and Thailand were sequenced and tested in both assays. …”
Được phát hành 2018
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2Bằng Holzmayer, Vera, Taylor, Russell, Kuhns, Mary C., Gawel, Susan H., Ndembi, Nicaise, Mbanya, Dora, Kaptue, Lazare, Rodgers, Mary A., Cloherty, Gavin“…We evaluated the use of DBS whole blood samples in the modified Abbott ARCHITECT anti-HCV assay, comparing assay performance against the standard assay run using DBS and venous plasma samples. 144 HCV positive and 104 HCV negative matched venous plasma and whole blood specimens were selected from a retrospective study with convenience sampling in Cameroon. …”
Được phát hành 2022
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3Bằng Butler, Emily K., Rodgers, Mary A., Coller, Kelly E., Barnaby, Devin, Krilich, Elizabeth, Olivo, Ana, Cassidy, Michael, Mbanya, Dora, Kaptue, Lazare, Ndembi, Nicaise, Cloherty, Gavin“…Samples were screened for HDV antibodies on the Abbott ARCHITECT instrument and for HDV RNA on the Abbott m2000 instrument by research assays. …”
Được phát hành 2018
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4Hepatitis C virus surveillance and identification of human pegivirus 2 in a large Cameroonian cohortBằng Rodgers, Mary A., Holzmayer, Vera, Vallari, Ana, Olivo, Ana, Forberg, Kenn, Fuhrman, Jill, Coller, Kelly E., Awazi, Bih, Kenmegne Sidje, Jules Bertrand, Frankel, Matthew B., Berg, Michael G., Mbanya, Dora, Ndembi, Nicaise, Cloherty, Gavin A.“…All specimens were screened for HCV using the Abbott RealTime HCV viral load assay and positive specimens with remaining volume were also screened for HPgV‐2 antibodies on the Abbott ARCHITECT instrument, followed by molecular characterization. …”
Được phát hành 2018
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5Bằng Rodgers, Mary A., Shah, Pir A., Anderson, Mark, Vallari, Ana S., Gersch, Jeffrey, Mbanya, Dora, Sauleda Oliveras, Silvia, Choudhry, Saad, Leary, Thomas P., Kuhns, Mary C., Dawson, George J., Cloherty, Gavin A., Lau, Daryl T.Y.“…To evaluate the clinical utility of HBsAg isoforms, we developed novel prototype assays on the ARCHITECT automated serology platform that specifically detects total-HBsAg (T-HBsAg), large (L-HBsAg), and middle (M-HBsAg) products of the S gene to determine the isoform composition of human specimens from acute and chronic HBV infection and during long-term nucleos(t)ide analog therapy. …”
Được phát hành 2023
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6Development and performance of prototype serologic and molecular tests for hepatitis delta infectionBằng Coller, Kelly E., Butler, Emily K., Luk, Ka-Cheung, Rodgers, Mary A., Cassidy, Michael, Gersch, Jeffrey, McNamara, Anne L., Kuhns, Mary C., Dawson, George J., Kaptue, Lazare, Bremer, Birgit, Wedemeyer, Heiner, Cloherty, Gavin A.“…Prototype molecular (RNA) and serologic (IgG) assays were developed for high-throughput testing on the Abbott m2000 and ARCHITECT systems, respectively. RNA detection was achieved through amplification of a ribozyme region target, with a limit of detection of 5 IU/ml. …”
Được phát hành 2018
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7Bằng Peluso, Michael J., Takahashi, Saki, Hakim, Jill, Kelly, J. Daniel, Torres, Leonel, Iyer, Nikita S., Turcios, Keirstinne, Janson, Owen, Munter, Sadie E., Thanh, Cassandra, Nixon, Christopher C., Hoh, Rebecca, Tai, Viva, Fehrman, Emily A., Hernandez, Yanel, Spinelli, Matthew A., Gandhi, Monica, Palafox, Mary-Ann, Vallari, Ana, Rodgers, Mary A., Prostko, John, Hackett, John, Trinh, Lan, Wrin, Terri, Petroplolous, Christos J., Chiu, Charles Y., Norris, Philip J., DiGermanio, Clara, Stone, Mars, Busch, Michael P., Elledge, Susanna K., Zhou, Xin X., Wells, James A., Shu, Albert, Kurtz, Theodore W., Pak, John E., Wu, Wesley, Burbelo, Peter D., Cohen, Jeffrey I., Rutishauser, Rachel L., Martin, Jeffrey N., Deeks, Steven G., Henrich, Timothy J., Rodriguez-Barraquer, Isabel, Greenhouse, Bryan“…Variations in sensitivity and durability were particularly dramatic for individuals with mild infection, who had consistently lower antibody titers and represent the majority of the infected population, with sensitivities often differing substantially from reported test characteristics (e.g., amongst commercial assays, sensitivity at 6 months ranged from 33% for ARCHITECT IgG to 98% for VITROS Total Ig). Thus, the ability to detect previous infection by SARS-CoV-2 is highly dependent on the severity of the initial infection, timing relative to infection, and the assay used. …”
Được phát hành 2021
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8Bằng Berg, Michael G., Olivo, Ana, Harris, Barbara J., Rodgers, Mary A., James, Linda, Mampunza, Samuel, Niles, Jonathan, Baer, Franklin, Yamaguchi, Julie, Kaptue, Lazare, Laeyendecker, Oliver, Quinn, Thomas C., McArthur, Carole, Cloherty, Gavin A.“…Individuals confirmed as reactive by the Abbott ARCHITECT HIV Ag/Ab Combo assay (n=1968) were measured by the Abbott RealTime HIV-1 viral load assay. …”
Được phát hành 2021
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