Loss of stearoyl-CoA desaturase 2 disrupts inflammatory response in macrophages

por Lin, Joseph B., Mora, Amy, Wang, Tzu Jui, Santeford, Andrea, Usmani, Darksha, Ligon, Marianne M., Mysorekar, Indira U., Apte, Rajendra S.
Publicado 2023

The Chlamydia effector CpoS modulates the inclusion microenvironment and restricts the interferon response by acting on Rab35

por Meier, Karsten, Jachmann, Lana H., Türköz, Gözde, Babu Sait, Mohammed Rizwan, Pérez, Lucía, Kepp, Oliver, Valdivia, Raphael H., Kroemer, Guido, Sixt, Barbara S.
Publicado 2023

African swine fever virus MGF-360-10L is a novel and crucial virulence factor that mediates ubiquitination and degradation of JAK1 by recruiting the E3 ubiquitin ligase HERC5

por Li, Dan, Peng, Jiangling, Wu, Junhuang, Yi, Jiamin, Wu, Panxue, Qi, Xiaolan, Ren, Jingjing, Peng, Gaochuang, Duan, Xianghan, Ru, Yi, Liu, Huanan, Tian, Hong, Zheng, Haixue
Publicado 2023

Crystal structure and induced stability of trimeric BxpB: implications for the assembly of BxpB-BclA complexes in the exosporium of Bacillus anthracis

por Chattopadhyay, Debasish, Walker, Dionna R., Rich-New, Shane T., Kearney, John F., Turnbough, Jr., Charles L.
Publicado 2023

Global analysis of putative phospholipases in Plasmodium falciparum reveals an essential role of the phosphoinositide-specific phospholipase C in parasite maturation

por Burda, Paul-Christian, Ramaprasad, Abhinay, Bielfeld, Sabrina, Pietsch, Emma, Woitalla, Anna, Söhnchen, Christoph, Singh, Mehar Nihal, Strauss, Jan, Sait, Aaron, Collinson, Lucy M., Schwudke, Dominik, Blackman, Michael J., Gilberger, Tim-Wolf
Publicado 2023

Systemic host inflammation induces stage-specific transcriptomic modification and slower maturation in malaria parasites

por Lansink, Lianne I. M., Skinner, Oliver P., Engel, Jessica A., Lee, Hyun Jae, Soon, Megan S. F., Williams, Cameron G., SheelaNair, Arya, Pernold, Clara P. S., Laohamonthonkul, Pawat, Akter, Jasmin, Stoll, Thomas, Hill, Michelle M., Talman, Arthur M., Russell, Andrew, Lawniczak, Mara, Jia, Xiaoxiao, Chua, Brendon, Anderson, Dovile, Creek, Darren J., Davenport, Miles P., Khoury, David S., Haque, Ashraful
Publicado 2023

Differential dysregulation of β-TrCP1 and -2 by HIV-1 Vpu leads to inhibition of canonical and non-canonical NF-κB pathways in infected cells

por Pickering, Suzanne, Sumner, Jonathan, Kerridge, Claire, Perera, Marianne, Neil, Stuart
Publicado 2023

Tixagevimab/cilgavimab for preventing COVID-19 during the Omicron surge: retrospective analysis of National Veterans Health Administration electronic data

por Young-Xu, Yinong, Epstein, Lauren, Marconi, Vincent C., Davey, Victoria, Korves, Caroline, Zwain, Gabrielle, Smith, Jeremy, Cunningham, Fran, Bonomo, Robert A., Ginde, Adit A.
Publicado 2023

Mrs4 loss of function in fungi during adaptation to the cystic fibrosis lung

por Murante, Daniel, Demers, Elora G., Kurbessoian, Tania, Ruzic, Marina, Ashare, Alix, Stajich, Jason E., Hogan, Deborah A.
Publicado 2023

SARS-CoV-2 ORF6 protein does not antagonize interferon signaling in respiratory epithelial Calu-3 cells during infection

por Li, Minghua, Ayyanathan, Kasirajan, Dittmar, Mark, Miller, Jesse, Tapescu, Iulia, Lee, Jae Seung, McGrath, Marisa E., Xue, Yong, Vashee, Sanjay, Schultz, David C., Frieman, Matthew B., Cherry, Sara
Publicado 2023

Regionalization of the antiviral response in the gastrointestinal tract to provide spatially controlled host/pathogen interactions

por Stanifer, Megan L., Karst, Stephanie M., Boulant, Steeve
Publicado 2023

Probing the drivers of Staphylococcus aureus biofilm protein amyloidogenesis and disrupting biofilms with engineered protein disaggregases

por Howard, Matthew K., Miller, Karlie R., Sohn, Brian S., Ryan, Jeremy J., Xu, Andy, Jackrel, Meredith E.
Publicado 2023

Ergosterol distribution controls surface structure formation and fungal pathogenicity

por Choy, Hau Lam, Gaylord, Elizabeth A., Doering, Tamara L.
Publicado 2023

Dual localization of receptor-type adenylate cyclases and cAMP response protein 3 unveils the presence of two putative signaling microdomains in Trypanosoma cruzi

por Chiurillo, Miguel A., Carlson, Joshua, Bertolini, Mayara S., Raja, Aqsa, Lander, Noelia
Publicado 2023

Adaptive variations in SARS-CoV-2 spike proteins: effects on distinct virus-cell entry stages

por Qing, Enya, Gallagher, Tom
Publicado 2023

The choline-binding proteins PspA, PspC, and LytA of Streptococcus pneumoniae and their interaction with human endothelial and red blood cells

por Vilhena, Cláudia, Du, Shanshan, Battista, Miriana, Westermann, Martin, Kohler, Thomas, Hammerschmidt, Sven, Zipfel, Peter F.
Publicado 2023

Ehrlichia Notch signaling induction promotes XIAP stability and inhibits apoptosis

por Patterson, LaNisha L., Byerly, Caitlan D., Solomon, Regina, Pittner, Nicholas, Bui, Duc Cuong, Patel, Jignesh, McBride, Jere W.
Publicado 2023

Ehrlichia Wnt SLiM ligand mimic deactivates the Hippo pathway to engage the anti-apoptotic Yap-GLUT1-BCL-xL axis

por Byerly, Caitlan D., Patterson, LaNisha L., Pittner, Nicholas A., Solomon, Regina N., Patel, Jignesh G., Rogan, Madison R., McBride, Jere W.
Publicado 2023

Species- and strain-specific differences in the phagocytosis of Prototheca: insights from live-cell imaging

por Haider, Mohammed J. A., Shave, Christopher D., Onyishi, Chinaemerem U., Jagielski, Tomasz, Lara-Reyna, Samuel, Frickel, Eva-Maria, May, Robin C.
Publicado 2023

Deep spatial profiling of Venezuelan equine encephalitis virus reveals increased genetic diversity amidst neuroinflammation and cell death during brain infection

por Williams, Evan P., Xue, Yi, Lee, Jasper, Fitzpatrick, Elizabeth A., Kong, Ying, Reichard, Walter, Writt, Haley, Jonsson, Colleen B.
Publicado 2023