SARS-CoV-2 Spike Furin Cleavage Site and S2′ Basic Residues Modulate the Entry Process in a Host Cell-Dependent Manner

por Lavie, Muriel, Dubuisson, Jean, Belouzard, Sandrine
Publicado 2022

Structural Insight into Terminal Galactose Recognition by Two Non-HBGA Binding GI.3 Noroviruses

por Wang, Chenlong, Kang, Huiling, Tan, Ming, Cong, Jingyuan, Su, Dan, Li, Xuemei, Chen, Yutao
Publicado 2022

Longitudinal Assessment of SARS-CoV-2-Specific T Cell Cytokine-Producing Responses for 1 Year Reveals Persistence of Multicytokine Proliferative Responses, with Greater Immunity As...

por Lin, Jonah, Law, Ryan, Korosec, Chapin S., Zhou, Christine, Koh, Wan Hon, Ghaemi, Mohammad Sajjad, Samaan, Philip, Ooi, Hsu Kiang, Matveev, Vitaliy, Yue, FengYun, Gingras, Anne-Claude, Estacio, Antonio, Buchholz, Megan, Cheatley, Patti Lou, Mohammadi, Avid, Kaul, Rupert, Pavinski, Katerina, Mubareka, Samira, McGeer, Allison J., Leis, Jerome A., Heffernan, Jane M., Ostrowski, Mario
Publicado 2022

Forkhead O Transcription Factor 4 Restricts HBV Covalently Closed Circular DNA Transcription and HBV Replication through Genetic Downregulation of Hepatocyte Nuclear Factor 4 Alpha...

por Li, Yuqi, He, Minjing, Gong, Ruijie, Wang, Ziteng, Lu, Lin, Peng, Shu, Duan, Zhiyun, Feng, Ying, Liu, Yi, Gao, Bo
Publicado 2022

FUBP3 Degrades the Porcine Epidemic Diarrhea Virus Nucleocapsid Protein and Induces the Production of Type I Interferon

por Dong, Sujie, Kong, Ning, Wang, Chunmei, Li, Youwen, Sun, Dage, Qin, Wenzhen, Zhai, Huanjie, Zhai, Xueying, Yang, Xinyu, Ye, Chenqian, Ye, Manqing, Liu, Changlong, Yu, Lingxue, Zheng, Hao, Tong, Wu, Yu, Hai, Zhang, Wen, Tong, Guangzhi, Shan, Tongling
Publicado 2022

Comparison of Crimean-Congo Hemorrhagic Fever Virus and Aigai Virus in Life Cycle Modeling Systems Reveals a Difference in L Protein Activity

por Pickin, Matthew J., Devignot, Stéphanie, Weber, Friedemann, Groschup, Martin H.
Publicado 2022

Repurposing the Kinase Inhibitor Mavelertinib for Giardiasis Therapy

por Michaels, Samantha A., Hulverson, Matthew A., Whitman, Grant R., Tran, Linh T., Choi, Ryan, Fan, Erkang, McNamara, Case W., Love, Melissa S., Ojo, Kayode K.
Publicado 2022

Functional Role of YnfA, an Efflux Transporter in Resistance to Antimicrobial Agents in Shigella flexneri

por Sen, Tanuka, Verma, Naresh K.
Publicado 2022

MBZM-N-IBT, a Novel Small Molecule, Restricts Chikungunya Virus Infection by Targeting nsP2 Protease Activity In Vitro, In Vivo, and Ex Vivo

por De, Saikat, Ghosh, Soumyajit, Keshry, Supriya Suman, Mahish, Chandan, Mohapatra, Chinmayee, Guru, Ankeeta, Mamidi, Prabhudutta, Datey, Ankita, Pani, Sweta Smita, Vasudevan, Dileep, Beuria, Tushar Kant, Chattopadhyay, Subhasis, Subudhi, Bharat Bhusan, Chattopadhyay, Soma
Publicado 2022

A Reduced F(420)-Dependent Nitrite Reductase in an Anaerobic Methanotrophic Archaeon

por Heryakusuma, Christian, Susanti, Dwi, Yu, Hang, Li, Zhou, Purwantini, Endang, Hettich, Robert L., Orphan, Victoria J., Mukhopadhyay, Biswarup
Publicado 2022

Mutation to ispA Produces Stable Small-Colony Variants of Pseudomonas aeruginosa That Have Enhanced Aminoglycoside Resistance

por Pitton, Melissa, Oberhaensli, Simone, Appiah, Fiona, Pagani, Jean-Luc, Fournier, Anne, Jakob, Stephan M., Que, Yok-Ai, Cameron, David R.
Publicado 2022

Dual Inhibition of Vacuolar-ATPase and TMPRSS2 Is Required for Complete Blockade of SARS-CoV-2 Entry into Cells

por Icho, Simoun, Rujas, Edurne, Muthuraman, Krithika, Tam, John, Liang, Huazhu, Landreth, Shelby, Liao, Mingmin, Falzarano, Darryl, Julien, Jean-Philippe, Melnyk, Roman A.
Publicado 2022

Validation of Clinical Risk Models for Clostridioides difficile-Attributable Outcomes

por Madden, Gregory R., Petri, William A., Costa, Deiziane V. S., Warren, Cirle A., Ma, Jennie Z., Sifri, Costi D.
Publicado 2022

In Vitro Selection of Remdesivir-Resistant SARS-CoV-2 Demonstrates High Barrier to Resistance

por Checkmahomed, Liva, Carbonneau, Julie, Du Pont, Venice, Riola, Nicholas C., Perry, Jason K., Li, Jiani, Paré, Bastien, Simpson, Shawn M., Smith, Martin A., Porter, Danielle P., Boivin, Guy
Publicado 2022

Antibiotic Exposure Leads to Reduced Phage Susceptibility in Vancomycin Intermediate Staphylococcus aureus (VISA)

por McCallin, Shawna, Menzi, Carmen, Lassen, Swenja, Daraspe, Jean, Oechslin, Frank, Moreillon, Philippe
Publicado 2022

Parasite Viability as a Measure of In Vivo Drug Activity in Preclinical and Early Clinical Antimalarial Drug Assessment

por Radohery, Georges F. R., Walz, Annabelle, Gumpp, Christin, Cherkaoui-Rbati, Mohammed H., Gobeau, Nathalie, Gower, Jeremy, Davenport, Miles P., Rottmann, Matthias, McCarthy, James S., Möhrle, Jörg J., Rebelo, Maria, Demarta-Gatsi, Claudia, Khoury, David S.
Publicado 2022

The Combination Treatment of Fosmanogepix and Liposomal Amphotericin B Is Superior to Monotherapy in Treating Experimental Invasive Mold Infections

por Gebremariam, Teclegiorgis, Gu, Yiyou, Alkhazraji, Sondus, Youssef, Eman, Shaw, Karen Joy, Ibrahim, Ashraf S.
Publicado 2022

Characterizing SARS-CoV-2 Viral Clearance Kinetics to Improve the Design of Antiviral Pharmacometric Studies

por Watson, James A., Kissler, Stephen M., Day, Nicholas P. J., Grad, Yonatan H., White, Nicholas J.
Publicado 2022

Linolenic Acid-Metronidazole: a Compound Relieving Drug Resistance and Inhibiting Helicobacter pylori

por Dai, Yuan-Yuan, Qin, Chun, Huang, Gan-Rong, Qin, Yan-Chun, Huang, Yong-Yi, Huang, Yan-Qiang, Zhao, Li-juan
Publicado 2022

Development of a Rapid Live SARS-CoV-2 Neutralization Assay Based on a qPCR Readout

por Lichtenegger, Sabine, Saiger, Sabine, Hardt, Melina, Kulnik, Susanne, Wagner, Gabriel E., Kleinhappl, Barbara, Assig, Karoline, Zauner, Andrea, Ober, Michelle, Kimpel, Janine, von Laer, Dorothee, Zatloukal, Kurt, Steinmetz, Ivo
Publicado 2022