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423por Michaud, Mickaël, Sukkurwala, Abdul Qader, Martins, Isabelle, Shen, Shensi, Zitvogel, Laurence, Kroemer, Guido“…Recently, we observed that overexpression of CD39, an ATP-degrading enzyme expressed on the cell surface, abolishes the immunogenicity of cell death, thus rendering cancers resistant against chemotherapy.…”
Publicado 2012
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424por Zeng, Fanning, Wind, Nicholas, Mcclenaghan, Conor, Verkuyl, J. Martin, Watson, Robert P., Nash, Mark S.“…GPR39 is a GPCR implicated as a regulator of gastrointestinal motility, although the mechanism remains elusive. …”
Publicado 2012
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428por Vanderhoeven, Jeroen P, Peterson, Suzanne E, Gannon, Elizabeth E, Mayock, Dennis E, Gammill, Hilary S“…STUDY DESIGN: We conducted a retrospective cohort study of 234 eligible singletons delivered after fetal lung maturity (FLM) testing prior to 39 weeks gestation at our center over a two year time period. …”
Publicado 2014
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429“…RESULTS: During the 8 year study period there was an average of 292′546 persons aged 5-39 and there were a total of 1122 deaths, certified as potential SCDs in 3.6% of cases. …”
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430
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431“…The proportions of CD8, B cells, CD4 and CD39-expressing cells were analysed by flow cytometry. …”
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432“…OBJECTIVE: The current study was carried out to adapt and validate a well-known tool to measure the QOL (i.e., Stroke-Aphasia Quality of Life-39; SAQOL-39) to Hindi. MATERIALS AND METHODS: We presented the original (English) version of the SAQOL-39 to a group of six Hindi-speaking Speech Language Pathologists hailing from the central and northern regions of India to examine the sociocultural suitability of items and indicate modifications, if any. …”
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433
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434“…OBJECTIVE: This study aimed to adapt and validate the widely-used stroke-aphasia quality of life (SAQOL-39) scale to Malayalam. MATERIALS AND METHODS: We required seven Malayalam-speaking Speech Language Pathologists (SLPs), hailing from different regions of Kerala, to examine the socio-cultural suitability of the original items in SAQOL-39 and indicate modifications, wherever necessary. …”
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435por Persu, Alexandre, Evenepoel, Lucie, Jin, Yu, Mendola, Antonella, Ngueta, Gérard, Yang, Wen-Yi, Gruson, Damien, Horman, Sandrine, Staessen, Jan A., Vikkula, Miikka“…The serine/threonine kinase With-No-Lysine (K) Kinase 1 (WNK1) activates the thiazide-sensitive Na(+)/Cl(−) cotransporter through phosphorylation of STE20/SPS1-related proline/alanine-rich kinase, another serine/threonine kinase encoded by STK39. The aim of this study was to look for association between WNK1 and STK39 gene variants, and blood pressure (BP) and hypertension. …”
Publicado 2016
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436por Hsieh, Joanne, Koseki, Masahiro, Molusky, Matthew M., Yakushiji, Emi, Ichi, Ikuyo, Westerterp, Marit, Iqbal, Jahangir, Chan, Robin B., Abramowicz, Sandra, Tascau, Liana, Takiguchi, Shunichi, Yamashita, Shizuya, Welch, Carrie L., Di Paolo, Gilbert, Hussain, M. Mahmood, Lefkowitch, Jay H., Rader, Daniel J., Tall, Alan R.“…We discovered that tetratricopeptide repeat (TPR) domain protein 39B (Ttc39b, C9orf52) (T39), a high density lipoprotein (HDL) gene discovered in human genome wide association studies (GWAS)(2), promotes the ubiquitination and degradation of LXR. …”
Publicado 2016
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437por Kang, Ji-feng, Luo, Yang, Tang, Bei-sha, Wan, Chang-min, Yang, Yang, Li, Kai, Liu, Zhen-hua, Sun, Qi-ying, Xu, Qian, Yan, Xin-xiang, Guo, Ji-feng“…Recently, RAB39B mutations were reported to be a causative factor in patients with Parkinson’s disease (PD). …”
Publicado 2016
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438por Ochoa-Repáraz, Javier, Colpitts, Sara L., Kircher, Christopher, Kasper, Eli J., Telesford, Kiel M., Begum-Haque, Sakhina, Pant, Anudeep, Kasper, Lloyd H.“…Conversely, a significant increase of the relative frequency of CD39(+) Treg cells was observed. In vivo, the protective effect of GALT-derived teriflunomide-induced CD39(+) Treg cells was established by adoptive transfer into recipient experimental autoimmune encephalomyelitis mice. …”
Publicado 2016
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439por Vyas, Krishna S., Hambrick, Rhodes H., Shakir, Afaaf, Morrison, Shane D., Gosman, Amanda A., Dobke, Marek, Vasconez, Henry C., Mardini, Samir, Granick, Mark S.Enlace del recurso
Publicado 2017
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440“…In the present study, the functions of ubiquitin-specific peptidase 39 (USP39) were investigated in the context of two vascular remodeling models (a mouse common carotid artery ligation and a pig bilateral saphenous vein-carotid artery interposition graft). …”
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