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1521por Syreeni, Anna, El-Osta, Assam, Forsblom, Carol, Sandholm, Niina, Parkkonen, Maikki, Tarnow, Lise, Parving, Hans-Henrik, McKnight, Amy J., Maxwell, Alexander P., Cooper, Mark E., Groop, Per-Henrik“…In this study, we investigated genetic polymorphisms of the SETD7, SUV39H1, and SUV39H2 methyltransferases as predictors of risk for micro- and macrovascular complications in type 1 diabetes. …”
Publicado 2011
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1522
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1523por Cohen, Limor, Azriel-Tamir, Hagit, Arotsker, Natan, Sekler, Israel, Hershfinkel, Michal“…Importantly, GPR39 also mediated ZnR-dependent upregulation of Na(+)/H(+) exchange activity as this activity was found in native colon tissue but not in tissue obtained from GPR39 knock-out mice. …”
Publicado 2012
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1524por Lang, Minglin, Wang, Lei, Fan, Qiangwang, Xiao, Guiran, Wang, Xiaoxi, Zhong, Yi, Zhou, Bing“…Zn is imported into the brain mainly through the solute-linked carrier (Slc) 39 family transporters. Using a genetically tractable Drosophila model, we found that the expression of dZip1, the orthologue of human Slc39 family transporter hZip1 in Drosophila, was altered in the brains of Aβ42-expressing flies, and Zn homeostasis could be modulated by forcible dZip1 expression changes. …”
Publicado 2012
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1525“…There have been few medium-term results reported for this prosthesis, however, and its migration pattern has not been analyzed. PATIENTS AND METHODS: 39 consecutive CUT femoral neck prostheses were implanted in 32 patients, mean age 37 (17–58) years, with symptomatic osteoarthritis and either less than 55 years of age or with an anatomic anomaly preventing implantation of a diaphyseal stem (n = 1). …”
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1526por Wang, Tao, Xu, Chao, Liu, Yanli, Fan, Kai, Li, Zhihong, Sun, Xing, Ouyang, Hui, Zhang, Xuecheng, Zhang, Jiahai, Li, Yanjun, MacKenzie, Farrell, Min, Jinrong, Tu, Xiaoming“…SUV39H1 contains a chromodomain in its N-terminus, which potentially plays a role in methyl-lysine recognition and SUV39H1 targeting. …”
Publicado 2012
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1527por Leal, Fabio E., Ndhlovu, Lishomwa C., Hasenkrug, Aaron M., Bruno, Fernanda R., Carvalho, Karina I., Wynn-Williams, Harry, Neto, Walter K., Sanabani, Sabri S., Segurado, Aluisio C., Nixon, Douglas F., Kallas, Esper G.“…CD4(+) T cells are the main target of infection and play a pivotal role in regulating immunity to HTLV and are hypothesized to participate in the pathogenesis of HAM/TSP. The CD39 ectonucleotidase receptor is expressed on CD4(+) T cells and based on co-expression with CD25, marks T cells with distinct regulatory (CD39(+)CD25(+)) and effector (CD39(+)CD25(−)) function. …”
Publicado 2013
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1528“…The same growth conditions impacted differently on the nonencapsulated R6, and its encapsulated progenitor D39. A semi-aerobic atmosphere and a raised concentration of uracil, a fundamental component of the D39 capsule, improved considerably D39 growth rate and biomass. …”
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1529por Jagannathan, Vidhya, Bannoehr, Jeanette, Plattet, Philippe, Hauswirth, Regula, Drögemüller, Cord, Drögemüller, Michaela, Wiener, Dominique J., Doherr, Marcus, Owczarek-Lipska, Marta, Galichet, Arnaud, Welle, Monika M., Tengvall, Katarina, Bergvall, Kerstin, Lohi, Hannes, Rüfenacht, Silvia, Linek, Monika, Paradis, Manon, Müller, Eliane J., Roosje, Petra, Leeb, Tosso“…This candidate causative variant is a missense variant in the SUV39H2 gene encoding a histone 3 lysine 9 (H3K9) methyltransferase, which mediates chromatin silencing. …”
Publicado 2013
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1530“…We sought to determine the O(2)-induced effects on the polarization of macrophages and the role of anti-inflammatory BRP-39 in macrophage phenotype and neonatal lung injury. …”
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1531por Engelken, Johannes, Carnero-Montoro, Elena, Pybus, Marc, Andrews, Glen K., Lalueza-Fox, Carles, Comas, David, Sekler, Israel, de la Rasilla, Marco, Rosas, Antonio, Stoneking, Mark, Valverde, Miguel A., Vicente, Rubén, Bosch, Elena“…Extreme differences in allele frequency between West Africans and Eurasians were observed for a leucine-to-valine substitution (Leu372Val) in the human intestinal zinc uptake transporter, ZIP4, yet no further evidence was found for a selective sweep around the ZIP4 gene (SLC39A4). By interrogating allele frequencies in more than 100 diverse human populations and resequencing Neanderthal DNA, we confirmed the ancestral state of this locus and found a strong geographical gradient for the derived allele (Val372), with near fixation in West Africa. …”
Publicado 2014
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1532por Valle, Marta, Estevez, Javier, Martial, Lisa Charlotte, Santamaria, Eva, Izquierdo, IñakiEnlace del recurso
Publicado 2014
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1533por Boonma, Prapaporn, Spinler, Jennifer K, Venable, Susan F, Versalovic, James, Tumwasorn, Somying“…Factors produced by two vancomycin-resistant lactobacilli, L. rhamnosus L34 (LR-L34) and L.casei L39 (LC-L39), suppressed the secretion and transcription of IL-8 without inhibiting C. difficile viability or toxin production. …”
Publicado 2014
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1534por Chowanadisai, Winyoo“…The zinc transporter ZIP12, which is encoded by the gene slc39a12, has previously been shown to be important for neuronal differentiation in mouse Neuro-2a neuroblastoma cells and primary mouse neurons and necessary for neurulation during Xenopus tropicalis embryogenesis. …”
Publicado 2014
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1535por Ly, Lindsey K., Underwood, Grace E., McCully, Lucy M., Bitzer, Adam S., Godino, Agustina, Bucci, Vanni, Brigham, Christopher J., Príncipe, Analía, Fischer, Sonia E., Silby, Mark W.“…Pseudomonas fluorescens SF4c and SF39a, strains isolated from wheat rhizosphere, have potential applications in plant growth promotion and biocontrol of fungal diseases of crop plants. …”
Publicado 2015
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1536“…We studied the effect of G9a and SUV39H1 inhibitors on viability and differentiation of AML cells and tested the cytotoxicity induced by combination of G9a and SUV39H1 inhibitors and various epigenetic drugs. …”
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1537por Sonnery-Cottet, Bertrand, Zayni, Rachad, Conteduca, Jacopo, Archbold, Pooler, Prost, Thierry, Carrillon, Yannick, Clechet, Julien, Thaunat, Mathieu“…Four patients with contralateral knee ligament surgery and 1 patient who sustained a traumatic rupture of his graft were excluded, leaving 39 patients for final evaluation. Clinical evaluation of knee function and laxity were recorded preoperatively and at a mean 24.2-month follow-up. …”
Publicado 2013
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1538por Abraham, Meike-Kristin, Nolte, Andrea, Reus, Rebekka, Behring, Andreas, Zengerle, Diane, Avci-Adali, Meltem, Hohmann, Jan David, Peter, Karlheinz, Schlensak, Christian, Wendel, Hans Peter, Krajewski, Stefanie“…METHODS AND FINDINGS: Our study aimed to develop an innovative bioactive stent coating that induces overexpression of CD39 in the atherosclerotic vessel. Therefore, a modified CD39-encoding mRNA was produced by in vitro transcription. …”
Publicado 2015
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1539por Reinert, Jochim, Richard, Bernhard C., Klafki, Hans W., Friedrich, Beate, Bayer, Thomas A., Wiltfang, Jens, Kovacs, Gabor G., Ingelsson, Martin, Lannfelt, Lars, Paetau, Anders, Bergquist, Jonas, Wirths, Oliver“…Aβ37 and Aβ39 were found to be widely distributed within the vasculature in the brains of the majority of studied SAD and FAD cases, the latter also presenting considerable amounts of Aβ37 containing NPs. …”
Publicado 2016
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1540“…RESULTS: A total of 13 case–control studies involving 39,736 subjects (9,237 cases and 10,838 controls on FAS rs2234767 and 8,957 cases and 10,704 controls on FASL rs763110) were included in the meta-analysis. …”
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