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  1. 173181
    “…Advanced age (aOR 0.97, 95% CI 0.96, 0.98, p < 0.001), longstanding T2DM (aOR 0.53, 95% CI 0.39, 0.72, p < 0.001), and non-statin therapy (aOR 0.25, 95% CI 0.16, 0.37, p < 0.001) were negatively associated with lipid control (LDL < 100 mg/dL) while using oral hypoglycemic drugs or insulin (aOR 2.01, 95% CI 1.45, 2.77, p < 0.001) and having cardiovascular comorbidity (aOR 3.92, 95% CI 3.00, 5.12, p < 0.001) were positively associated with lipid control. …”
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    Status of lipid control in Bangladeshi subjects with type 2 diabetes mellitus on lipid-lowering drugs: a multicenter, facility-based, cross-sectional study
  2. 173182
    “…In contrast, the expression of TIMP-2, an inhibitor of MMP-2, was lower in the RA than in the non-RA samples (25 ± 12 versus 39 ± 9 cells/high-power field; P = 0.01). Synovial tissue expressions of MMP-2, MMP-14, and TIMP-2 were virtually undetectable in normal synovial tissue samples. …”
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    Active synovial matrix metalloproteinase-2 is associated with radiographic erosions in patients with early synovitis
  3. 173183
    “…The initial blood biochemical studies before the administration of carbon tetrachloride showed that the mean AST and ALT levels were 39.8±5.2 IU/L and 59.1±11.7 IU/L, respectively. …”
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    Quantitative Evaluation of Liver Function with MRI Using Gd-EOB-DTPA
  4. 173184
    “…The following variables were significantly (p < 0.05) lower following the fast as compared to before the fast: white blood cell count (5.68 ± 0.24 vs. 4.99 ± 0.19 10(3)·μL(-1)), blood urea nitrogen (13.07 ± 0.58 vs. 10.14 ± 0.59 mg·dL(-1)), blood urea nitrogen/creatinine (14.74 ± 0.59 vs. 11.67 ± 0.68), protein (6.95 ± 0.07 vs. 6.77 ± 0.06 g·dL(-1)), total cholesterol (171.07 ± 4.57 vs. 138.69 ± 4.39 mg·dL(-1)), LDL-C (98.38 ± 3.89 vs. 76.07 ± 3.53 mg·dL(-1)), HDL-C (55.65 ± 2.50 vs. 47.58 ± 2.19 mg·dL(-1)), SBP (114.65 ± 2.34 vs. 105.93 ± 2.12 mmHg), and DBP (72.23 ± 1.59 vs. 67.00 ± 1.43 mmHg). …”
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    Effect of a 21 day Daniel Fast on metabolic and cardiovascular disease risk factors in men and women
  5. 173185
    por Dastani, Zari, Hivert, Marie-France, Timpson, Nicholas, Perry, John R. B., Yuan, Xin, Scott, Robert A., Henneman, Peter, Heid, Iris M., Kizer, Jorge R., Lyytikäinen, Leo-Pekka, Fuchsberger, Christian, Tanaka, Toshiko, Morris, Andrew P., Small, Kerrin, Isaacs, Aaron, Beekman, Marian, Coassin, Stefan, Lohman, Kurt, Qi, Lu, Kanoni, Stavroula, Pankow, James S., Uh, Hae-Won, Wu, Ying, Bidulescu, Aurelian, Rasmussen-Torvik, Laura J., Greenwood, Celia M. T., Ladouceur, Martin, Grimsby, Jonna, Manning, Alisa K., Liu, Ching-Ti, Kooner, Jaspal, Mooser, Vincent E., Vollenweider, Peter, Kapur, Karen A., Chambers, John, Wareham, Nicholas J., Langenberg, Claudia, Frants, Rune, Willems-vanDijk, Ko, Oostra, Ben A., Willems, Sara M., Lamina, Claudia, Winkler, Thomas W., Psaty, Bruce M., Tracy, Russell P., Brody, Jennifer, Chen, Ida, Viikari, Jorma, Kähönen, Mika, Pramstaller, Peter P., Evans, David M., St. Pourcain, Beate, Sattar, Naveed, Wood, Andrew R., Bandinelli, Stefania, Carlson, Olga D., Egan, Josephine M., Böhringer, Stefan, van Heemst, Diana, Kedenko, Lyudmyla, Kristiansson, Kati, Nuotio, Marja-Liisa, Loo, Britt-Marie, Harris, Tamara, Garcia, Melissa, Kanaya, Alka, Haun, Margot, Klopp, Norman, Wichmann, H.-Erich, Deloukas, Panos, Katsareli, Efi, Couper, David J., Duncan, Bruce B., Kloppenburg, Margreet, Adair, Linda S., Borja, Judith B., Wilson, James G., Musani, Solomon, Guo, Xiuqing, Johnson, Toby, Semple, Robert, Teslovich, Tanya M., Allison, Matthew A., Redline, Susan, Buxbaum, Sarah G., Mohlke, Karen L., Meulenbelt, Ingrid, Ballantyne, Christie M., Dedoussis, George V., Hu, Frank B., Liu, Yongmei, Paulweber, Bernhard, Spector, Timothy D., Slagboom, P. Eline, Ferrucci, Luigi, Jula, Antti, Perola, Markus, Raitakari, Olli, Florez, Jose C., Salomaa, Veikko, Eriksson, Johan G., Frayling, Timothy M., Hicks, Andrew A., Lehtimäki, Terho, Smith, George Davey, Siscovick, David S., Kronenberg, Florian, van Duijn, Cornelia, Loos, Ruth J. F., Waterworth, Dawn M., Meigs, James B., Dupuis, Josee, Richards, J. Brent
    Publicado 2012
    “…We conducted a meta-analysis of genome-wide association studies in 39,883 individuals of European ancestry to identify genes associated with metabolic disease. …”
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    Novel Loci for Adiponectin Levels and Their Influence on Type 2 Diabetes and Metabolic Traits: A Multi-Ethnic Meta-Analysis of 45,891 Individuals
  6. 173186
    “…However, in the RCP group, in addition to pain distribution towards the lower limbs, they were complaining about muscular myotonia and sensational disorder and 88% also had low back pain. 94 of them were men and 106 were women.106 subjects (80.5%) were urban residents and 39 (19.5%) rural residents. There were 42.5% housewife, 21.5% employee, 15% workers, 9.5% self-employed, and 8.5% were unemployed. …”
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    Magnetic resonance imaging findings in low back pain and lower extremity radicular chronic pain
  7. 173187
    “…Maximum mean increases from baseline were: pulse rate, +8.73 to 12.76 beats/min with either treatment alone and +17.67 to 20.85 beats/min with LDX + VXR; systolic BP, +4.32 to 6.56 mmHg with either treatment alone and +12.96 to 13.78 mmHg with LDX + VXR; diastolic BP, +5.39 to 5.74 mmHg with either treatment alone and +12.09 to 12.46 mmHg with LDX + VXR. …”
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    An Open-Label Investigation of the Pharmacokinetic Profiles of Lisdexamfetamine Dimesylate and Venlafaxine Extended-Release, Administered Alone and in Combination, in Healthy Adults
  8. 173188
    “…In addition, telehealth intervention reduced the inpatient cost in the nonsenior group from $814.93 (SD 1000.40) to US $217.39 (SD 771.01, P=.001) and the total cost per month from US $954.78 (SD 998.70) to US $485.06 (SD 952.47, P<.001). …”
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    Clinical Outcome and Cost-Effectiveness of a Synchronous Telehealth Service for Seniors and Nonseniors with Cardiovascular Diseases: Quasi-Experimental Study
  9. 173189
    Publicado 2013
    “…FINDINGS: 1206 children were randomly assigned to clinically driven (n=606) versus routine laboratory monitoring (n=600), and groups A (n=397), B (n=404), and C (n=405). 47 (8%) children on clinically driven monitoring versus 39 (7%) on routine laboratory monitoring had a new WHO stage 4 event or died (hazard ratio [HR] 1·13, 95% CI 0·73–1·73, p=0·59; non-inferiority criterion met). …”
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    Routine versus clinically driven laboratory monitoring and first-line antiretroviral therapy strategies in African children with HIV (ARROW): a 5-year open-label randomised factorial trial
  10. 173190
    por Fall, Tove, Hägg, Sara, Mägi, Reedik, Ploner, Alexander, Fischer, Krista, Horikoshi, Momoko, Sarin, Antti-Pekka, Thorleifsson, Gudmar, Ladenvall, Claes, Kals, Mart, Kuningas, Maris, Draisma, Harmen H. M., Ried, Janina S., van Zuydam, Natalie R., Huikari, Ville, Mangino, Massimo, Sonestedt, Emily, Benyamin, Beben, Nelson, Christopher P., Rivera, Natalia V., Kristiansson, Kati, Shen, Huei-yi, Havulinna, Aki S., Dehghan, Abbas, Donnelly, Louise A., Kaakinen, Marika, Nuotio, Marja-Liisa, Robertson, Neil, de Bruijn, Renée F. A. G., Ikram, M. Arfan, Amin, Najaf, Balmforth, Anthony J., Braund, Peter S., Doney, Alexander S. F., Döring, Angela, Elliott, Paul, Esko, Tõnu, Franco, Oscar H., Gretarsdottir, Solveig, Hartikainen, Anna-Liisa, Heikkilä, Kauko, Herzig, Karl-Heinz, Holm, Hilma, Hottenga, Jouke Jan, Hyppönen, Elina, Illig, Thomas, Isaacs, Aaron, Isomaa, Bo, Karssen, Lennart C., Kettunen, Johannes, Koenig, Wolfgang, Kuulasmaa, Kari, Laatikainen, Tiina, Laitinen, Jaana, Lindgren, Cecilia, Lyssenko, Valeriya, Läärä, Esa, Rayner, Nigel W., Männistö, Satu, Pouta, Anneli, Rathmann, Wolfgang, Rivadeneira, Fernando, Ruokonen, Aimo, Savolainen, Markku J., Sijbrands, Eric J. G., Small, Kerrin S., Smit, Jan H., Steinthorsdottir, Valgerdur, Syvänen, Ann-Christine, Taanila, Anja, Tobin, Martin D., Uitterlinden, Andre G., Willems, Sara M., Willemsen, Gonneke, Witteman, Jacqueline, Perola, Markus, Evans, Alun, Ferrières, Jean, Virtamo, Jarmo, Kee, Frank, Tregouet, David-Alexandre, Arveiler, Dominique, Amouyel, Philippe, Ferrario, Marco M., Brambilla, Paolo, Hall, Alistair S., Heath, Andrew C., Madden, Pamela A. F., Martin, Nicholas G., Montgomery, Grant W., Whitfield, John B., Jula, Antti, Knekt, Paul, Oostra, Ben, van Duijn, Cornelia M., Penninx, Brenda W. J. H., Davey Smith, George, Kaprio, Jaakko, Samani, Nilesh J., Gieger, Christian, Peters, Annette, Wichmann, H.-Erich, Boomsma, Dorret I., de Geus, Eco J. C., Tuomi, TiinaMaija, Power, Chris, Hammond, Christopher J., Spector, Tim D., Lind, Lars, Orho-Melander, Marju, Palmer, Colin Neil Alexander, Morris, Andrew D., Groop, Leif, Järvelin, Marjo-Riitta, Salomaa, Veikko, Vartiainen, Erkki, Hofman, Albert, Ripatti, Samuli, Metspalu, Andres, Thorsteinsdottir, Unnur, Stefansson, Kari, Pedersen, Nancy L., McCarthy, Mark I., Ingelsson, Erik, Prokopenko, Inga
    Publicado 2013
    “…In the IV analysis, we demonstrated novel evidence for a causal relationship between adiposity and incident heart failure (hazard ratio, 1.19 per BMI-unit increase; 95% CI, 1.03–1.39) and replicated earlier reports of a causal association with type 2 diabetes, metabolic syndrome, dyslipidemia, and hypertension (odds ratio for IV estimator, 1.1–1.4; all p<0.05). …”
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    The Role of Adiposity in Cardiometabolic Traits: A Mendelian Randomization Analysis
  11. 173191
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    Ecological and socio-cultural factors influencing plant management in Náhuatl communities of the Tehuacán Valley, Mexico
  12. 173192
    por Chen, Yu, Copeland, Wade K, Vedanthan, Rajesh, Grant, Eric, Lee, Jung Eun, Gu, Dongfeng, Gupta, Prakash C, Ramadas, Kunnambath, Inoue, Manami, Tsugane, Shoichiro, Tamakoshi, Akiko, Gao, Yu-Tang, Yuan, Jian-Min, Shu, Xiao-Ou, Ozasa, Kotaro, Tsuji, Ichiro, Kakizaki, Masako, Tanaka, Hideo, Nishino, Yoshikazu, Chen, Chien-Jen, Wang, Renwei, Yoo, Keun-Young, Ahn, Yoon-Ok, Ahsan, Habibul, Pan, Wen-Harn, Chen, Chung-Shiuan, Pednekar, Mangesh S, Sauvaget, Catherine, Sasazuki, Shizuka, Yang, Gong, Koh, Woon-Puay, Xiang, Yong-Bing, Ohishi, Waka, Watanabe, Takashi, Sugawara, Yumi, Matsuo, Keitaro, You, San-Lin, Park, Sue K, Kim, Dong-Hyun, Parvez, Faruque, Chuang, Shao-Yuan, Ge, Wenzhen, Rolland, Betsy, McLerran, Dale, Sinha, Rashmi, Thornquist, Mark, Kang, Daehee, Feng, Ziding, Boffetta, Paolo, Zheng, Wei, He, Jiang, Potter, John D
    Publicado 2013
    “…Elevated risk of death from cardiovascular disease was also observed at lower categories of body mass index (hazard ratio 1.19 (95% confidence interval 1.02 to 1.39) and 2.16 (1.37 to 3.40) for body mass index ranges 15.0-17.4 and <15.0, respectively), compared with the reference range. …”
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    Association between body mass index and cardiovascular disease mortality in east Asians and south Asians: pooled analysis of prospective data from the Asia Cohort Consortium
  13. 173193
    “…At follow-up, parents in the intervention condition (n=643) showed significantly less unsafe behavior compared to parents in the control condition (n=649): top of staircase (23.91% vs 32.19%; OR 0.65, 95% CI 0.50-0.85); bottom of staircase (63.53% vs 71.94%; OR 0.69, 95% CI 0.53-0.88); top and bottom of staircase (68.94% vs 78.28%; OR 0.62, 95% CI 0.48-0.81); storage of cleaning products (30.33% vs 39.91%; OR 0.67, 95% CI 0.53-0.85); bathing of the child (23.46% vs 32.25%; OR 0.65, 95% CI 0.51-0.84); drinking hot fluids (34.84% vs 41.73%; OR 0.76, 95% CI 0.61-0.96); using rear hotplates (79.34% vs 85.27%; OR 0.67, 95% CI 0.50-0.90); and the total risk score in which a higher score indicates more unsafe behavior (mean 13.63, SD 6.12 vs mean 15.34, SD 6.07; beta –1.59, 95% CI –2.26 to –0.93). …”
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    Effectiveness of Web-Based Tailored Advice on Parents’ Child Safety Behaviors: Randomized Controlled Trial
  14. 173194
    “…Parameters of the sinusoidal network that we also routinely quantify include the radius of the sinusoids (4.8 ± 2.25 μm), the branching angle (32.5 ± 11.2°), the length of intersection branches (23.93 ± 5.9 μm), the number of intersection nodes per mm(3) (120.3 × 103 ± 42.1 × 10(3)), the average length of sinusoidal vessel per mm(3) (5.4 × 10(3) ± 1.4 × 10(3)mm) and the percentage of vessel volume in relation to the whole liver volume (15.3 ± 3.9) (mean ± standard deviation). Moreover, the provided parameters of the bile canalicular network are: length of the first-order branches (7.5 ± 0.6 μm), length of the second-order branches (10.9 ± 1.8 μm), length of the dead-end branches (5.9 ± 0.7 μm), the number of intersection nodes per mm(3) (819.1 × 10(3) ± 180.7 × 10(3)), the number of dead-end branches per mm(3) (409.9 × 10(3) ± 95.6 × 10(3)), the length of the bile canalicular network per mm(3) (9.4 × 10(3) ± 0.7 × 10(3) mm) and the percentage of the bile canalicular volume with respect to the total liver volume (3.4 ± 0.005). …”
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    Protocols for staining of bile canalicular and sinusoidal networks of human, mouse and pig livers, three-dimensional reconstruction and quantification of tissue microarchitecture by image processing and analysis
  15. 173195
    “…Of the 663 An. gambiae s.l. collected, 385 were successfully tested by PCR among which 235 (61.0%) were identified as An. gambiae s.s. while 150 (39.0%) were identified as An. arabiensis. Compared with data collected before the scale-up of ITNs, daily entomological inoculation rates (EIRs) were consistently lower for An. gambiae s.l. …”
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    Persistently high estimates of late night, indoor exposure to malaria vectors despite high coverage of insecticide treated nets
  16. 173196
    “…Five studies were finally included, with 1117 patients, of these 831 received a dose of omalizumab of 75 mg (183 patients, 16.38%), 150 mg (163 patients, 14.59%), 300 mg (437 patients, 39.12%) or 600 mg (21 patients, 1.8%), as a single dose, or every 4 weeks until 24 weeks maximum. …”
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    Omalizumab vs. placebo in the management of chronic idiopathic urticaria: a systematic review
  17. 173197
    “…Antigen assay Compared to microscopy, the CCA test showed considerable heterogeneity; meta‐analytic sensitivity estimate was 39%, 95% CI 6% to 73%; specificity 78%, 95% CI 55% to 100% (four studies, 901 participants). …”
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    Circulating antigen tests and urine reagent strips for diagnosis of active schistosomiasis in endemic areas
  18. 173198
    por Papais-Alvarenga, Regina Maria, Vasconcelos, Claudia Cristina Ferreira, Carra, Adriana, de Castillo, Ibis Soto, Florentin, Sara, Diaz de Bedoya, Fernando Hamuy, Mandler, Raul, de Siervi, Luiza Campanella, Pimentel, Maria Lúcia Vellutini, Alvarenga, Marina Papais, Papais Alvarenga, Marcos, Grzesiuk, Anderson Kuntz, Gama Pereira, Ana Beatriz Calmon, Gomes Neto, Antonio Pereira, Velasquez, Carolina, Soublette, Carlos, Fleitas, Cynthia Veronica, Diniz, Denise Sisteroli, Armas, Elizabeth, Batista, Elizabeth, Hernandez, Freda, Pereira, Fernanda Ferreira Chaves da Costa, Siqueira, Heloise Helena, Cabeça, Hideraldo, Sanchez, Jose, Brooks, Joseph Bruno Bidin, Gonçalves, Marcus Vinicius, Barroso, Maria Cristina Del Negro, Ravelo, Maria Elena, Castillo, Maria Carlota, Ferreira, Maria Lúcia Brito, Rocha, Maria Sheila Guimarães, Parolin, Monica Koncke Fiuza, Molina, Omaira, Marinho, Patricia Beatriz Christino, Christo, Paulo Pereira, Brant de Souza, Renata, Pessanha Neto, Silvio, Camargo, Solange Maria das Graças, Machado, Suzana Costa, Neri, Vanderson Carvalho, Fragoso, Yara Dadalti, Alvarenga, Helcio, Thuler, Luiz Claudio Santos
    Publicado 2015
    “…Except in ADEM, the disease onset occurred between 20 and 39 years old, early onset in 8.2% of all cases, and late onset occurred in 8.9%. …”
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    Central Nervous System Idiopathic Inflammatory Demyelinating Disorders in South Americans: A Descriptive, Multicenter, Cross-Sectional Study
  19. 173199
    “…In contrast, the patients with Stanford B dissection showed it in 39 (11.11%) of 351 cases; P = 0.481. The anatomical variant defined as vertebral artery of direct origin of the aortic arch was more frequent in the patients with Stanford B dissection (5.12%). …”
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    Incidence of Branching Patterns Variations of the Arch in Aortic Dissection in Chinese Patients
  20. 173200
    “…In an exploratory analysis of a predefined subgroup of 502 patients with poor prognosis disease, 332 (66%) died (174 in the standard chemotherapy group and 158 in the bevacizumab group), and a significant difference in overall survival was noted between women who received bevacizumab plus chemotherapy and those who received chemotherapy alone (restricted mean survival time 34·5 months [95% CI 32·0–37·0] with standard chemotherapy vs 39·3 months [37·0–41·7] with bevacizumab; log-rank p=0·03). …”
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    Standard chemotherapy with or without bevacizumab for women with newly diagnosed ovarian cancer (ICON7): overall survival results of a phase 3 randomised trial
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