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  1. 173261
    “…ECHS1 is involved in valine (−log (p = 3.39E00)), isoleucine degradation (p = 0.00457), fatty acid β-oxidation (−log(p) = 2.83E00), and drug metabolism:cytochrome P450 (z-score = 2.07985196) pathways. …”
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    “Omics” data integration and functional analyses link Enoyl-CoA hydratase, short chain 1 to drug refractory dilated cardiomyopathy
  2. 173262
    por Pinto, A., Adams, S., Ahring, K., Allen, H., Almeida, M.F., Garcia-Arenas, D., Arslan, N., Assoun, M., Atik Altınok, Y., Barrio-Carreras, D., Belanger Quintana, A., Bernabei, S.M., Bontemps, C., Boyle, F., Bruni, G., Bueno-Delgado, M., Caine, G., Carvalho, R., Chrobot, A., Chyż, K., Cochrane, B., Correia, C., Corthouts, K., Daly, A., De Leo, S., Desloovere, A., De Meyer, A., De Theux, A., Didycz, B., Dijsselhof, M.E., Dokoupil, K., Drabik, J., Dunlop, C., Eberle-Pelloth, W., Eftring, K., Ekengren, J., Errekalde, I., Evans, S., Foucart, A., Fokkema, L., François, L., French, M., Forssell, E., Gingell, C., Gonçalves, C., Gökmen Özel, H., Grimsley, A., Gugelmo, G., Gyüre, E., Heller, C., Hensler, R., Jardim, I., Joost, C., Jörg-Streller, M., Jouault, C., Jung, A., Kanthe, M., Koç, N., Kok, I.L., Kozanoğlu, T., Kumru, B., Lang, F., Lang, K., Liegeois, I., Liguori, A., Lilje, R., Ļubina, O., Manta-Vogli, P., Mayr, D., Meneses, C., Newby, C., Meyer, U., Mexia, S., Nicol, C., Och, U., Olivas, S.M., Pedrón-Giner, C., Pereira, R., Plutowska-Hoffmann, K., Purves, J., Re Dionigi, A., Reinson, K., Robert, M., Robertson, L., Rocha, J.C., Rohde, C., Rosenbaum-Fabian, S., Rossi, A., Ruiz, M., Saligova, J., Gutiérrez-Sánchez, A., Schlune, A., Schulpis, K., Serrano-Nieto, J., Skarpalezou, A., Skeath, R., Slabbert, A., Straczek, K., Giżewska, M., Terry, A., Thom, R., Tooke, A., Tuokkola, J., van Dam, E., van den Hurk, T.A.M., van der Ploeg, E.M.C., Vande Kerckhove, K., Van Driessche, M., van Wegberg, A.M.J., van Wyk, K., Vasconcelos, C., Velez García, V., Wildgoose, J., Winkler, T., Żółkowska, J., Zuvadelli, J., MacDonald, A.
    Publicado 2018
    “…A second stage Phe-free L-amino acid supplement containing a higher protein equivalent was introduced by 41% (n = 39/95) of centres at infant age 26–36 weeks (mainly from Germany, Austria, Northern and Eastern Europe) and 37% (n = 35/95) at infant age > 1y mainly from Southern Europe. 53% (n = 50/95) of centres recommended a second stage Phe-free L-amino acid supplement in a spoonable or semi-solid form. …”
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    Weaning practices in phenylketonuria vary between health professionals in Europe
  3. 173263
    “…RESULTS: HER2 IHC scores of 3+, 2+, 1+, and 0 were seen in 31 (2.6%), 105 (8.8%), 475 (39.7%), and 584 (48.9%) tumors, respectively. HER2 gene amplification was seen in 24/29 tumors with an IHC score of 3+ (82.8%; unreadable in 2/31), 12/102 tumors with an IHC score of 2+ (11.8%; unreadable in 2/104), and 0 tumors with IHC score of 1+ (0/10). …”
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    Significance of HER2 protein expression and HER2 gene amplification in colorectal adenocarcinomas
  4. 173264
    “…Alternating magnetic field (AMF) was used to create controlled mild hyperthermia (39-42°C) and facilitate controlled cargo (fluorescein) release from the thermosensitive liposomes. …”
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    Magnetic Heating Stimulated Cargo Release with Dose Control using Multifunctional MR and Thermosensitive Liposome
  5. 173265
    “…For n=302: Q1(adherence) yes (Y) 252(83.4%),No 13(4.3%), sometimes 37(12.2%); Q2 (non-adherence): Y 210(69.5%), No 92 (30.5%); Q3 (lifestyle changes): Weight 168 (55.6%), Exercise 237 (78.5%), Stress 152 (50.3%), Carb control 142 (47.0%), Won’t change 18 (5.6%); Q4 (reminder): Voice 50 (16.6%), Text 203 (67.2%), Doctor’s staff 61 (20.1%), No reminder 30 (9.9%); Q5 (frequency of reminder): qday 107 (35.4%), qwk 104 (34.4%), qmonth 50 (16.6%), none 39 (12.9%); Q6 (pay for app): Y 51 (16.9%), No 248 (82.1%); Q7 (DM): Y 32 (10.6%), No 262 (86.8%), not know if diabetic 8 (2.6%); Q8 (type of DM): type 1 =5(1.7%), Type 2=24(7.9%), gestational=2(1.0%), No diabetes 262 (86.8%), not know if they have diabetes 9 (3.0%); Q9(HTN): Y 66 (21.9%), No 224 (74.2%),not know 12 (4.0%). …”
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    MON-144 Free Diabetes Mhealth Apps and a Patient Survey: Is Medication Adherence a Concern?
  6. 173266
    “…The mean (SD) age of the cohort with MDD was 39.1 (10.9) years, and the mean (SD) age of healthy controls was 37.0 (11.0) years. …”
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    Association of Repetitive Transcranial Magnetic Stimulation Treatment With Subgenual Cingulate Hyperactivity in Patients With Major Depressive Disorder: A Secondary Analysis of a Randomized Clinical Trial
  7. 173267
    “…HIV-infected individuals with a BMI <25 gained more weight at 1, 2 and 5 years post-index date compared to controls with most of these gains taking place at year 1 (3.4±7.8 vs. 2.2±7.1 Kg, 3.9±8.6 vs. 3±8 Kg, 4.4±9.8 vs. 4±9.1 Kg change from baseline at 1, 2 and 5 years respectively, all p<0.01). …”
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    SAT-093 Effect of HIV Infection and Antiretroviral Therapy Use on Body Weight and Body Weight Changes over a 5-Year Period in US Veterans
  8. 173268
    “…The proportion of patients achieving a reduction in HbA1c ≥0.5% without experiencing severe hypoglycemia was 47.2% in the 5 mg group vs. 21.3% for PBO, with 3.52 (95% CI 2.39, 5.21) greater odds of achieving this endpoint in those receiving 5 mg. …”
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    SAT-LB025 Analysis of Benefit/Risk in the Subgroup of Patients with BMI of >=27 Kg/m(2) in the Dapagliflozin DEPICT-1 and -2 Trials in Type 1 Diabetes
  9. 173269
    “…At 1 month, 3 months, 6 months, 9 months and 12 months after BS, patients lost 11.3 ± 5.0 kg (female: 10.0 ± 3.9 kg, male: 14.8 ± 6.0 kg, p<0.001), 19.3 ± 6.4 kg (female: 17.8 ± 4.4 kg, male: 25.5 ± 9.2 kg, p<0.01), 26.0 ± 8.8 kg (female: 24.7 ± 6.8 kg, male: 30.1 ± 13.2 kg, p=0.15), 28.7 ± 7.8 kg (female: 28.5 ± 7.8 kg, male: 29.6 ± 8.2 kg, p=0.77) and 30.1 ±8.1 kg (female: 30.0 ±8.2 kg, male: 30.8 ±8.4 kg, p=0.83) of body weight respectively. …”
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    SAT-116 Efficacy of Bariatric Surgery in Improving Obesity in South Asians
  10. 173270
    “…Age-adjusted first-year rates of all-cause mortality decreased by 6% from 24·5 (95% CI 23·4 to 39·2) to 23·0 (22·0 to 24·1) per 100 person-years. …”
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    20-year trends in cause-specific heart failure outcomes by sex, socioeconomic status, and place of diagnosis: a population-based study
  11. 173271
    “…For patients with erosive bleeding, the most common bleeding site detected was the pancreatic remnant (43.48%); others included the hepatic artery (39.13%), splenic artery (13.04%), and left gastric artery (4.35%). …”
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    Two forms of one complication: Late erosive and nonerosive postpancreatectomy hemorrhage following laparoscopic pancreaticoduodenectomy
  12. 173272
    por Waterson, James, Bedner, Arkadiusz
    Publicado 2019
    “…RESULTS: Initial analysis showed a mean average of 4.50 alarms per infusion in the general critical care pump population as opposed to the whole hospital rate of 1.39. In the pediatric intensive care unit (PICU) group, the alarms per infusion value was significantly above the mean average for all critical care areas, with 8.61 alarms per infusion. …”
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    Types and Frequency of Infusion Pump Alarms and Infusion-Interruption to Infusion-Recovery Times for Critical Short Half-Life Infusions: Retrospective Data Analysis
  13. 173273
    “…In total, 41 participants with RA and T2D were randomised, and 39 eligible participants were treated (age 62.72 ± 9.97 years, 74.4% female sex). …”
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    Anti-interleukin-1 treatment in patients with rheumatoid arthritis and type 2 diabetes (TRACK): A multicentre, open-label, randomised controlled trial
  14. 173274
    “…Compared to women delivering by ERCS, those who had a planned VBAC were significantly more likely to have uterine rupture (0.24%, n = 69 versus 0.04%, n = 17, adjusted odds ratio [aOR] 7.3, 95% confidence interval [CI] 3.9–13.9, p < 0.001), a blood transfusion (1.14%, n = 324 versus 0.50%, n = 226, aOR 2.3, 95% CI 1.9–2.8, p < 0.001), puerperal sepsis (0.27%, n = 76 versus 0.17%, n = 78, aOR 1.8, 95% CI 1.3–2.7, p = 0.002), and surgical injury (0.17% versus 0.09%, n = 40, aOR 3.0, 95% CI 1.8–4.8, p < 0.001) and experience adverse perinatal outcomes including perinatal death, admission to a neonatal unit, resuscitation requiring drugs and/or intubation, and an Apgar score < 7 at 5 minutes (7.99%, n = 2,049 versus 6.37%, n = 2,570, aOR 1.6, 95% CI 1.5–1.7, p < 0.001). …”
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    Planned mode of delivery after previous cesarean section and short-term maternal and perinatal outcomes: A population-based record linkage cohort study in Scotland
  15. 173275
    “…Mean CHA(2)DS(2)-VASc scores (n = 1,369) increased with age from 1.1 (<60 years) to 3.9 (≥85 years); 72% of ≥65 years had ≥1 additional stroke risk factor other than age/sex. …”
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    Estimated stroke risk, yield, and number needed to screen for atrial fibrillation detected through single time screening: a multicountry patient-level meta-analysis of 141,220 screened individuals
  16. 173276
    “…Lumbar puncture showed increased cerebral spinal fluid (CSF) protein of 1.25g/L (0.1-0.4) and mildly reduced glucose of 2.1mmol/L (2.2-3.9). CSF was negative for acid fast bacilli, lyme disease, cryptococcal antigen, PCR for viruses and TB, culture and extensive immunological screening. …”
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    52. Not every rheumatologic headache is giant cell arteritis: a case of aseptic meningitis on a background of rheumatoid arthritis
  17. 173277
    “…Black individuals were less likely than White individuals to be prescribed SGLT2 inhibitors (OR 0.50, 95% CI 0.39–0.65; p < 0.001) and GLP-1 agonists (OR 0.45, 95% CI 0.35–0.57; p < 0.001). …”
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    Disparities in glycaemic control, monitoring, and treatment of type 2 diabetes in England: A retrospective cohort analysis
  18. 173278
    por Zhang, Hua, Lan, Xiang, Peng, Bing, Li, Bo
    Publicado 2019
    “…Patients who underwent TLPD had less intraoperative blood loss [weighted mean difference (WMD) = -260.08 mL, 95% confidence interval (CI): (-336.02, -184.14) mL, P < 0.00001], a lower blood transfusion rate [odds ratio (OR) = 0.51, 95%CI: 0.36-0.72, P = 0.0001], a lower perioperative overall morbidity (OR = 0.82, 95%CI: 0.73-0.92, P = 0.0008), a lower wound infection rate (OR = 0.48, 95%CI: 0.34-0.67, P < 0.0001), a lower pneumonia rate (OR = 0.72, 95%CI: 0.60-0.85, P = 0.0002), a shorter duration of intensive care unit (ICU) stay [WMD = -0.28 d, 95%CI (-2.88, -1.29) d, P < 0.00001] and a shorter length of hospital stay [WMD = -3.05 d, 95%CI (-3.93, -2.17), P < 0.00001], a lower rate of discharge to a new facility (OR = 0.55, 95%CI: 0.39-0.78, P = 0.0008), and a lower 30-d readmission rate (OR = 0.81, 95%CI: 0.68-0.95, P = 0.10) than those who underwent OPD. …”
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    Is total laparoscopic pancreaticoduodenectomy superior to open procedure? A meta-analysis
  19. 173279
    “…Most of the participants (30%) belonged to 50–64 years of age group followed by 30–39 years (23%) and 40–49 years (22%) of age group, respectively. …”
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    2285 Patient navigation training: Community-engaged workforce development
  20. 173280
    “…RESULTS/ANTICIPATED RESULTS: There were 39 patients in the final cohort; thirteen of whom who participated in the pilot project, POET (Perioperative Educational Tool). …”
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    3228 POET: A perioperative educational tool as an adjunct to enhanced recovery after surgery in patients undergoing minimally invasive gynecologic oncology surgery
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