“…Univariate rate ratios for conditions listed by public health agencies as conferring high risk were 2.75 (95% CI 1.96–3.88, p = 6 × 10(−9)) for type 1 diabetes, 1.60 (95% CI 1.48–1.74, p = 8 × 10(−30)) for type 2 diabetes, 1.49 (95% CI 1.37–1.61, p = 3 × 10(−21)) for ischemic heart disease, 2.23 (95% CI 2.08–2.39, p = 4 × 10(−109)) for other heart disease, 1.96 (95% CI 1.83–2.10, p = 2 × 10(−78)) for chronic lower respiratory tract disease, 4.06 (95% CI 3.15–5.23, p = 3 × 10(−27)) for chronic kidney disease, 5.4 (95% CI 4.9–5.8, p = 1 × 10(−354)) for neurological disease, 3.61 (95% CI 2.60–5.00, p = 2 × 10(−14)) for chronic liver disease, and 2.66 (95% CI 1.86–3.79, p = 7 × 10(−8)) for immune deficiency or suppression. …”
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“…The ADC values were significantly lower among patients with EGFR-positive mutation ([1.19 ± 0.37] × 10(−3) mm(2)/s vs. [1.50 ± 0.53] × 10(−3) mm(2)/s, t = 3.38, P = 0.001) and high Ki-67 PI ([1.28 ± 0.39] × 10(−3) mm(2)/s vs. [1.67 ± 0.77] × 10(−3) mm(2)/s, t = 2.88, P = 0.005). …”
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“…Several secondary outcomes differed across populations randomized to VLNCs, including mean total CPD across weeks, with linear trends lower in participants receiving 0.4 mg/g (−0.28 [95%CI, −0.39 to −0.18]; P < .001) and 2.4 mg/g (−0.13 [95%CI, −0.25 to −0.01]; P < .001) doses compared with those receiving the 15.8 mg/g dose (0.30 [95% CI, 0.19 to 0.41]). …”
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“…Of these, 21 women (26%) had high EC-pY397-FAK expression that was associated with estrogen receptor positivity (71% vs 46%; P = .04), progesterone receptor positivity (67% vs 39%; P = .03), high Ki67 (86% vs 41%; P < .001), 4-immunohistochemically stained luminal-B (52% vs 8%; P < .001), higher tumor category (T3/T4 category: 90% vs 59%; P = .01), high lymph node category (N2-3 category: 43% vs 5%; P < .001), and high tumor node metastasis stage (IIIA-IIIC: 90% vs 66%; P = .03). …”
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“…Participants with f-FTLD (n = 100) with a known pathogenic variant (MAPT [n = 28], GRN [n = 33], or C9orf72 [n = 39]) were grouped according to disease stage (ie, Clinical Dementia Rating [CDR] plus National Alzheimer’s Coordinating Center [NACC] FTLD module). …”
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“…Mortality was higher in COVID-19 AKI versus COVID-19 patients without AKI (60.5% versus 27.4%, p < 0.001), and AKI was an independent predictor of mortality (OR 3.27, 95% CI 2.39 to 4.48). Compared with AKI controls, COVID-19 AKI was observed in a higher proportion of men (58.9% versus 51%, p = 0.04) and lower proportion with white ethnicity (74.7% versus 86.9%, p = 0.003); was more frequently associated with cerebrovascular disease (11.8% versus 6.0%, p = 0.006), chronic lung disease (28.0% versus 19.3%, p = 0.007), diabetes (24.7% versus 17.9%, p = 0.03), and CKD (34.2% versus 20.0%, p < 0.001); and was more likely to be hospital acquired (61.2% versus 46.4%, p < 0.001). …”
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“…We found no significant differences in FIBTEM variables between mild and moderate to severe cases (median amplitude at 10 min, 13 mm [range 8–20; IQR 11–15] vs 12 mm [range 6–25; IQR 10–15; p=0·68]; and median maximum clot firmness, 15 mm [range 9–60; IQR 13–21] vs 17 mm [range 7–39; IQR 13–23; p=0·21]); and no hyperfibrinolysis (maximum lysis >15%). …”
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“…There were small reductions in LDL from baseline to follow-up (control = −0.14 mmol/L [95% CI −0.48, 0.19), BS: −0.39 mmol/L [95% CI −0.59, −0.19], SF: −0.14 mmol/L [95% CI −0.34, 0.07]), but these were not significantly different: BS versus control p = 0.338; SF versus control p = 0.790. …”
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“…In March and April 2020, regression-adjusted use rate per 10 000 persons changed by −28.2 (95% CI, −30.5 to −25.9) and −64.5 (95% CI, −66.8 to −62.2) for colonoscopies; −149.1 (95% CI, −162.0 to −16.2) and −342.1 (95% CI, −355.0 to −329.2) for mammograms; −60.0 (95% CI, −63.3 to −54.7) and −118.1 (95% CI, −112.4 to −113.9) for hemoglobin A(1c) tests; −300.5 (95% CI, −346.5 to −254.5) and −369.0 (95% CI, −414.7 to −323.4) for child vaccines; −4.6 (95% CI, −5.3 to −3.9) and −10.9 (95% CI, −11.6 to −10.2) for musculoskeletal surgery; −1.1 (95% CI, −1.4 to −0.7) and −3.4 (95% CI, −3.8 to −3.0) for cataract surgery; −13.4 (95% CI, −14.6 to −12.2) and −31.4 (95% CI, −32.6 to −30.2) for magnetic resonance imaging; and −581.1 (95% CI, −612.9 to −549.3) and −1465 (95% CI, −1496 to −1433) for in-person office visits. …”
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“…The absorbed dose in the nucleus was 3.9-fold higher for panitumumab-DOTA-[(177)Lu]Lu than panitumumab-DOTA-[(111)In]In and 7.7-fold greater than panitumumab-MCP-[(111)In]In. …”
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“…Baseline PDDS was significantly associated with functional test performance in participants with MS (mixed model–based estimate of most significant feature across functional tests [β]: finger-tapping: β=–43.64, P<.001; DSST: β=–5.47, P=.005; walk and balance: β=–.39, P=.001; finger-to-nose: β=.01, P=.01). Longitudinal Neuro-QoL scores were also significantly associated with functional tests (finger-tapping with Upper Extremity Function: β=.40, P<.001; walk and balance with Lower Extremity Function: β=–99.18, P=.02; DSST with Cognitive Function: β=1.60, P=.03). …”
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“…There was no significant difference in LBR per embryo transfer (25/64, 39.1%, vs 22/71, 31.0%; OR 1.43, 95% CI 0.70 to 2.91) after antioxidant pretreatment versus no pretreatment. …”
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“…The median follow-up was 24.1 months (range, 0.3-104.7 months), and the median OS was 44.2 months (95% CI, 39.2-48.8 months). The median PFS was 12.9 months (95% CI, 11.6-14.2 months), and the median time to WSP was 42.5 months (95% CI, 36.8-53.5 months). …”
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“…The pregnant patients experienced higher rates of intensive care unit admission (39.5% vs 17.0%; P<.01; adjusted odds ratio, 5.2; 95% confidence interval, 1.5–17.5). …”
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“…The iodine level of visceral leishmaniasis patient was affected by HIV (B -38.02 [95% CI: − 41.98 - -34.06]), DDS (B 25 .84 [95% CI: 22.57–29.1]), smoking (B -12.34 [95% CI: − 15.98 - -8.7]), chronic illness (B -5.14 [95% CI: − 7.82 - -2.46]), and regular physical exercise (B 5.82 [95% CI: 0.39–11.26]). The serum vitamin D level of visceral leishmaniasis patient was affected by HIV (B -9.43 [95% CI: − 10.92 - -7.94]), DDS (B 16.24 [95% CI: 14.89–17.58]), malaria (B -0.61 [95% CI: − 3.37 - -3.37]), and family size (B -1.15 [95% CI: − 2.03 - -0.28]). …”
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“…RÉSULTATS: Au sein d’une population de 1565 patients souffrant de maladies chroniques, 56 personnes atteintes de psoriasis (80,4 % de femmes, 48,6 ans en moyenne) étaient incluses : – 19,6 % ont eu des difficultés à trouver un médecin disponible ; – 46,4 % ont consulté leur médecin moins souvent que d’habitude ; – 39,3 % ont été contraints d’annuler ou de reporter leurs consultations ou leurs interventions chirurgicales. – Parmi les patients sous traitement de fond (n = 45), 13,3 % ont totalement ou temporairement arrêté leur traitement de fond ; – 48,2 % n’ont pas eu accès à une information spécifique liée au psoriasis et 19,6 % ont bénéficié d’une information qui n’a pas été jugée suffisante. …”
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“…Les femmes rapportaient plus souvent une peau plus sèche liée au confinement (50,5 % vs 39,6 %, p = 0,0009). Les patients avec une peau dite sensible étaient plus à même de rapporter des modifications cutanées lors du confinement (29 % vs 15 %, p < 0,00001) globalement et dans les 3 pays. …”
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“…Les principales raisons pour lesquelles ils pourraient ne pas poursuivre les TLC étaient la qualité de l’examen clinique (89 %), des problèmes techniques/connexion (43 %), un lien humain insuffisant (39 %). Trois cent vingt-six (64 %) ont réalisé des télé-expertises (TLX), respectant les règles de sécurité (31 %) ou non (69 %). …”
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“…Tout patient adulte hospitalisé en réanimation au CHU de Lille dans le cadre de la COVID19 était inclus et bénéficiait d’un examen systématique du tégument par un dermatologue sénior. RÉSULTATS: Au total, 39 patients ont été examinés (34 hommes, 5 femmes) avec un âge moyen de 60,6 ans. …”
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“…In our individual participant data meta-analysis, we found treatment significantly decreased P falciparum prevalence (adjusted RR [ARR] 0·46, 95% CI 0·40–0·53; p<0·0001; 15 648 individuals; 11 studies), anaemia (ARR 0·85, 0·77–0·92; p<0·0001; 15 026 individuals; 11 studies), and subsequent clinical malaria (ARR 0·50, 0·39–0·60; p<0·0001; 1815 individuals; four studies) across transmission settings. …”
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