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173541por Weinberg, Laurence, Li, Stephanie Ying, Louis, Maleck, Karp, Jadon, Poci, Nadia, Carp, Bradly Samuel, Miles, Lachlan Fraser, Tully, Patrick, Hahn, Robert, Karalapillai, Dharshi, Lee, Dong-Kyu“…Most studies (n = 249; 78.3%) used an absolute threshold to define hypotension; 150 (60.5%) reported SBP, 117 (47.2%) reported MAP, and 12 (4.8%) reported diastolic blood pressure (DBP). 126 (39.6%) used a relative threshold to define hypotension. …”
Publicado 2022
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173542por Indraratna, Praveen, Biswas, Uzzal, McVeigh, James, Mamo, Andrew, Magdy, Joseph, Vickers, Dominic, Watkins, Elaine, Ziegl, Andreas, Liu, Hueiming, Cholerton, Nicholas, Li, Joan, Holgate, Katie, Fildes, Jennifer, Gallagher, Robyn, Ferry, Cate, Jan, Stephen, Briggs, Nancy, Schreier, Guenter, Redmond, Stephen J, Loh, Eugene, Yu, Jennifer, Lovell, Nigel H, Ooi, Sze-Yuan“…Over a mean follow-up of 193 days, the intervention was associated with a significant reduction in unplanned hospital readmissions (21 in TCC vs 41 in the control arm; P=.02), including cardiac readmissions (11 in TCC vs 25 in the control arm; P=.03), and higher rates of cardiac rehabilitation completion (20/51, 39% vs 9/49, 18%; P=.03) and medication adherence (57/76, 75% vs 37/74, 50%; P=.002). …”
Publicado 2022
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173543por Michaeli, Jennia, Michaeli, Ofir, Rozitzky, Ariel, Grisaru-Granovsky, Sorina, Feldman, Naomi, Srebnik, Naama“…Increased NICU admission was found for neonates who were SGA compared with neonates who were AGA (group 2-TP: 182 neonates [6.0%] and group 3-FN: 328 neonates [3.9%] vs group 1-FP: 51 neonates [0.9%] and group 4-TN: 704 neonates [0.8%]; P <.001), as was increased rate of low Apgar score (eg, at 1 minute: group 2-TP: 149 neonates [4.9%] and group 3-FN: 384 neonates [4.5%] vs group 1-FP: 124 neonates [2.2%] and group 4-TN: 1595 neonates [1.9%]; P < .001). …”
Publicado 2022
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173544por Gelanew, Tesfaye, Seyoum, Berhanu, Mulu, Andargachew, Mihret, Adane, Abebe, Markos, Wassie, Liya, Gelaw, Baye, Sorsa, Abebe, Merid, Yared, Muchie, Yilkal, Teklemariam, Zelalem, Tesfaye, Bezalem, Osman, Mahlet, Jebessa, Gutema, Atinafu, Abay, Hailu, Tsegaye, Habte, Antenehe, Kenea, Dagaga, Gadisa, Anteneh, Admasu, Desalegn, Tesfaye, Emnet, Bates, Timothy A., Bulcha, Jote Tafese, Tschopp, Rea, Tsehay, Dareskedar, Mullholand, Kim, Howe, Rawleigh, Genetu, Abebe, Tafesse, Fikadu G., Abdissa, Alemseged“…The overall seroprevalence was 39.6%. The lowest (24.5%) and the highest (48.0%) seroprevalence rates were found in Hiwot Fana Specialized Hospital in Harar and ALERT Hospital in Addis Ababa, respectively. …”
Publicado 2022
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173545por Nyberg, Tommy, Ferguson, Neil M, Nash, Sophie G, Webster, Harriet H, Flaxman, Seth, Andrews, Nick, Hinsley, Wes, Bernal, Jamie Lopez, Kall, Meaghan, Bhatt, Samir, Blomquist, Paula, Zaidi, Asad, Volz, Erik, Aziz, Nurin Abdul, Harman, Katie, Funk, Sebastian, Abbott, Sam, Hope, Russell, Charlett, Andre, Chand, Meera, Ghani, Azra C, Seaman, Shaun R, Dabrera, Gavin, De Angelis, Daniela, Presanis, Anne M, Thelwall, Simon“…FINDINGS: The adjusted hazard ratio (HR) of hospital attendance (not necessarily resulting in admission) with omicron compared with delta was 0·56 (95% CI 0·54–0·58); for hospital admission and death, HR estimates were 0·41 (0·39–0·43) and 0·31 (0·26–0·37), respectively. Omicron versus delta HR estimates varied with age for all endpoints examined. …”
Publicado 2022
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173546por Netto, Lucas C, Ibrahim, Karim Y, Picone, Camila M, Alves, Ana Paula P S, Aniceto, Eliane V, Santiago, Mariana R, Parmejani, Patrícia S S, Aikawa, Nadia E, Medeiros-Ribeiro, Ana C, Pasoto, Sandra G, Yuki, Emily F N, Saad, Carla G S, Pedrosa, Tatiana, Lara, Amanda N, Ceneviva, Carina, Bonfa, Eloisa, Kallas, Esper G, Avelino-Silva, Vivian I“…Median IgG titres were 48·7 AU/mL (IQR 26·6–88·2) in people with HIV compared with 75·2 AU/mL (50·3–112·0) in people with no known immunosuppression (p<0·0001); and median NAb activity was 46·2% (26·9–69·7) compared with 60·8% (39·8–79·9; p<0·0001). In people with HIV who had CD4 counts less than 500 cells per μL seroconversion rates, NAb positivity, and NAb activity were lower than in those with CD4 counts of at least 500 cells per μL. …”
Publicado 2022
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173547por Ho, Thao-Quyen H., Bissell, Michael C. S., Kerlikowske, Karla, Hubbard, Rebecca A., Sprague, Brian L., Lee, Christoph I., Tice, Jeffrey A., Tosteson, Anna N. A., Miglioretti, Diana L.“…Regardless of modality, cumulative probabilities of false-positive results were substantially lower for biennial vs annual screening (overall recall, 35.7 to 38.1 vs 49.6 to 56.3; short-interval follow-up, 10.3 to 10.5 vs 16.6 to 17.8; and biopsy recommendation, 6.6 to 6.7 vs 11.2 to 11.7); older vs younger age groups (eg, among annual screening in women ages 70-79 vs 40-49, recall, 39.8 to 47.0 vs 60.8 to 68.0; short-interval follow-up, 13.3 to 14.2 vs 20.7 to 20.9; and biopsy recommendation, 9.1 to 9.3 vs 13.2 to 13.4); and women with entirely fatty vs extremely dense breasts (eg, among annual screening in women aged 50-59 years, recall, 29.1 to 36.3 vs 58.8 to 60.4; short-interval follow-up, 8.9 to 11.6 vs 19.5 to 19.8; and biopsy recommendation, 4.9 to 8.0 vs 15.1 to 15.3). …”
Publicado 2022
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173548por Mosha, Jacklin F, Kulkarni, Manisha A, Lukole, Eliud, Matowo, Nancy S, Pitt, Catherine, Messenger, Louisa A, Mallya, Elizabeth, Jumanne, Mohamed, Aziz, Tatu, Kaaya, Robert, Shirima, Boniface A, Isaya, Gladness, Taljaard, Monica, Martin, Jacklin, Hashim, Ramadhan, Thickstun, Charles, Manjurano, Alphaxard, Kleinschmidt, Immo, Mosha, Franklin W, Rowland, Mark, Protopopoff, Natacha“…FINDINGS: 84 clusters comprising 39 307 households were included in the study between May 11 and July 2, 2018. 147 230 LLINs were distributed among households between Jan 26 and Jan 28, 2019. …”
Publicado 2022
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173549MicroRNA regulatory networks associated with abnormal muscle repair in survivors of critical illnesspor Walsh, Christopher J., Escudero King, Carlos, Gupta, Muskan, Plant, Pamela J., Herridge, Margaret J., Mathur, Sunita, Hu, Pingzhao, Correa, Judy, Ahmed, Sameen, Bigot, Anne, dos Santos, Claudia C., Batt, Jane“…Constitutive overexpression of miR‐744‐5p, a known regulator of myogenesis, significantly inhibited AB1167 and C2C12 myoblast differentiation (fusion index AB1167 miR‐744‐5p mimic or scrambled‐miR transfected myoblasts 8.31 ± 7.00% vs. 40.29 ± 9.37% respectively, P < 0.001; myosin heavy chain expression miR‐744‐5p mimic or scrambled‐miR transfected myoblasts 0.92 ± 0.39 vs. 13.53 ± 5.5 respectively, P = 0.01). CONCLUSIONS: Combined functional transcriptomics identified 36 miRs including miRs‐424‐3p/5p, ‐490‐3p, and ‐744‐5p as potential regulators of gene networks associated with recovery of muscle mass and strength following critical illness. …”
Publicado 2022
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173550por Moon, Sung Woo, Lee, Sang Hoon, Woo, Ala, Leem, Ah Young, Lee, Su Hwan, Chung, Kyung Soo, Kim, Eun Young, Jung, Ji Ye, Kang, Young Ae, Park, Moo Suk, Kim, Young Sam, Kim, Chang Oh, Kim, Song Yee“…To determine cutoffs, 335 participants aged 19–39 years (mean age 35.2 ± 3.6 years, 75.2% male) were selected as the healthy and younger reference group, and 4135 participants aged ≥40 years (mean age 56.4 ± 8.4 years, 65.1% male) were selected as the study group. …”
Publicado 2022
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173551“…Respondents who were married were significantly less likely to experience symptoms of general health problems (AOR, 0.10; 95% CI, 0.02–0.39), depression (AOR, 0.31; 95% CI, 0.22–0.82), insomnia (AOR, 0.46; 95% CI, 0.20–1.03), and loneliness (AOR, 0.31; 95% CI, 0.10-0.92). …”
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173552por Alandejani, Faisal, Alabed, Samer, Garg, Pankaj, Goh, Ze Ming, Karunasaagarar, Kavita, Sharkey, Michael, Salehi, Mahan, Aldabbagh, Ziad, Dwivedi, Krit, Mamalakis, Michail, Metherall, Pete, Uthoff, Johanna, Johns, Chris, Rothman, Alexander, Condliffe, Robin, Hameed, Abdul, Charalampoplous, Athanasios, Lu, Haiping, Plein, Sven, Greenwood, John P., Lawrie, Allan, Wild, Jim M., de Koning, Patrick J. H., Kiely, David G., Van Der Geest, Rob, Swift, Andrew J.“…Minimal RA area mean and SD DSC metric for observer 1 vs observer 2, automatic measurements vs observer 1 and automatic measurements vs observer 2 was 89.8 ± 3.9 cm(2), 87.0 ± 5.8 cm(2) and 91.8 ± 4.8 cm(2). …”
Publicado 2022
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173553por Yang, Tingting, Shen, Qianqian, Wang, Siyu, Dong, Tianfang, Liang, Liang, Xu, Fan, He, Youfang, Li, Chunlei, Luo, Fang, Liang, Jiahong, Tang, Chunhui, Yang, Jinghui“…The number of cases of mild, moderate and severe BPD were 39 (15.6%), 185 (74.0%) and 26 (10.4%), respectively. …”
Publicado 2022
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173554por Fu, Suochao, Zhang, Yu, Ai, Fuzhi, Wang, Jianhua, Wu, Zenghui, Ma, Xiangyang, Wu, Zixiang, Wang, Zheng, Lei, Wei, Xia, Hong“…Subgroup analysis showed the 8-hole group (161.35 ± 27.17 N) had the lower maximum axial pull-out force as compared with the 4-hole group (217.29 ± 49.68 N), 6-hole group (228.39 ± 57.83 N), and straight pore group (237.55 ± 35.96 N) (P < 0.01). …”
Publicado 2022
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173555por Ko, Emily R., Henao, Ricardo, Frankey, Katherine, Petzold, Elizabeth A., Isner, Pamela D., Jaehne, Anja K., Allen, Nakia, Gardner-Gray, Jayna, Hurst, Gina, Pflaum-Carlson, Jacqueline, Jayaprakash, Namita, Rivers, Emanuel P., Wang, Henry, Ugalde, Irma, Amanullah, Siraj, Mercurio, Laura, Chun, Thomas H., May, Larissa, Hickey, Robert W., Lazarus, Jacob E., Gunaratne, Shauna H., Pallin, Daniel J., Jambaulikar, Guruprasad, Huckins, David S., Ampofo, Krow, Jhaveri, Ravi, Jiang, Yunyun, Komarow, Lauren, Evans, Scott R., Ginsburg, Geoffrey S., Tillekeratne, L. Gayani, McClain, Micah T., Burke, Thomas W., Woods, Christopher W., Tsalik, Ephraim L.“…A total of 13 participants (1.7%) were American Indian, 13 (1.7%) were Asian, 368 (48.7%) were Black, 131 (17.4%) were Hispanic, 3 (0.4%) were Native Hawaiian or Pacific Islander, 297 (39.3%) were White, and 60 (7.9%) were of unspecified race and/or ethnicity. …”
Publicado 2022
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173556por Cermisoni, Greta Chiara, Reschini, Marco, Piccinni, Marie-Pierre, Lombardelli, Letizia, Logiodice, Federica, Sarais, Veronica, Giacomini, Elisa, Signorelli, Simona, Cecchele, Anna, Viganò, Paola“…Inclusion criteria were female age 18–39 years, with a BMI between 18 and 25 kg/m(2). …”
Publicado 2022
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173557por Brousseau, Nicholas, Morin, Laurianne, Ouakki, Manale, Savard, Patrice, Quach, Caroline, Longtin, Yves, Cheng, Matthew P., Carignan, Alex, Dufresne, Simon F., Leduc, Jean-Michel, Lavallée, Christian, Gauthier, Nicolas, Bestman-Smith, Julie, Arrieta, Maria-Jesus, Ishak, Magued, Lévesque, Simon, Martin, Philippe, De Serres, Gaston“…La séroprévalence moindre a été associée au fait de travailler dans une unité de soins intensifs (rapport de prévalence ajusté 0,47, IC à 95 % 0,30–0,71) ou aux urgences (rapport de prévalence ajusté 0,61, IC à 95 % 0,39–0,98). INTERPRÉTATION: Les travailleurs de la santé des hôpitaux du Québec ont été exposés à un risque élevé d’infection par le SRAS-CoV-2, particulièrement lors des éclosions. …”
Publicado 2022
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173558por Verma, Abhishek, Hine, Ashley M., Joelson, Andrew, Mei, Rena, Pitts, Robert A., Lebwohl, Benjamin, Axelrad, Jordan E.“…RESULTS: Of 298 PLWH, 119 (39.9%) had a CD4 count below 200, 195 (65.4%) were hospitalized, and 137 (46.0%) had enteric infection. …”
Publicado 2022
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173559por Padwa, Howard, Huang, David, Mooney, Larissa, Grella, Christine E., Urada, Darren, Bell, Douglas S., Bass, Brittany, Boustead, Anne E.“…CUD-documented patients were significantly more likely than CU-documented patients to have HIV/AIDS (OR = 6.70; 95% CI 2.10–21.39), other substance use disorder (OR = 5.88; 95% CI 2.42–14.22), depression (OR = 2.85; 95% CI 1.90–4.26), and anxiety (OR = 2.19: 95% CI 1.57–3.05) diagnoses. …”
Publicado 2022
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173560“…When included in the diet at 60 g/kg, GP reduced the proportion of saturated fatty acids in the yolk (31.6 vs. 32.9%, p = 0.001) and that of monounsaturated fatty acids (39.5 vs. 41.4%, p < 0.001), while it increased the percentage of polyunsaturated fatty acids (28.9 vs. 25.7%, p < 0.001). …”
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