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  1. 173661
    “…We further describe influenza and COVID-19 vaccine coverage for the 2020-2021 season (week 40 of 2020 to week 39 of 2021), with the latter differentiated by vaccine brand. …”
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    Representativeness, Vaccination Uptake, and COVID-19 Clinical Outcomes 2020-2021 in the UK Oxford-Royal College of General Practitioners Research and Surveillance Network: Cohort Profile Summary
  2. 173662
    “…On the EORTC QLQ-C30 functional scales, patients receiving PARPi reported significantly better scores (mean ± SE) for physical functioning (80.0 ± 2.4 vs 71.9 ± 3.4; p < 0.05) and social functioning (82.0 ± 6.2 vs 63.6 ± 3.7; p < 0.05) and, on the symptom scales, reported significantly better scores for constipation (1.9 ± 1.8 vs 18.7 ± 3.2; p < 0.001), breast symptoms (0.4 ± 3.9 vs 13.3 ± 2.6; p < 0.01), arm symptoms (2.6 ± 1.3 vs 11.4 ± 2.4; p = 0.001), and systemic therapy side effects (13.5 ± 1.8 vs 29.4 ± 2.3; p < 0.001). …”
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    Real-world patient-reported outcomes and physician satisfaction with poly (ADP-ribose) polymerase inhibitors versus chemotherapy in patients with germline BRCA1/2-mutated human epidermal growth factor receptor 2–negative advanced breast cancer from the United States, Europe, and Israel
  3. 173663
    “…In the remaining 1258 patients, the association of serum S100A12 with the risk of HHF tended to be more pronounced [1.39 (1.06–1.83)]. When including the gold standard HF marker NT‐proBNP in the model, the prognostic value of S100A12 for HHF did not reach significance. …”
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    Increased serum S100A12 levels are associated with higher risk of acute heart failure in patients with type 2 diabetes
  4. 173664
    “…The evaluated treatments were 1: (TP-U) (control) = supplement with 24% crude protein (CP) containing urea as a source of non-protein nitrogen (NPN; 3%) and soybean meal, 2: (TP-PRU) = 24% CP supplement containing post-ruminal urea (PRU; 3.6%) and soybean meal; 3: (NPN-U-PRU) = 24% CP supplement containing urea + post-ruminal urea (U = 3% and PRU = 3.9%), without soybean meal; 4: (NPN-PRU) = supplement with 24% CP containing post-ruminal urea (7.5%), without soybean meal. …”
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    Effects of Post-Ruminal Urea Supplementation during the Seasonal Period on Performance and Rumen Microbiome of Rearing Grazing Nellore Cattle
  5. 173665
    “…We developed and externally validated PMHnet-alpha, a neural-network based survival model for risk-stratification in ischemic heart disease that leverages the multitude of clinical features available in modern electronical health records. METHODS: We included 39,746 IHD patients from the regional Heart Registry that had been subjected to a coronary angiography between 2006 and 2017 with confirmed coronary artery disease. …”
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    PMHnet-alpha: development and validation of a neural network based discrete-time survival model for mortality prediction in ischemic heart disease
  6. 173666
    “…The patients evaluated via e-consultation had less mortality (2.5% vs 3.9%, p<0.001), Figure 2. CONCLUSIONS: An outpatient care program that includes an e-consultation has shown to reduce waiting times significantly and is a safe model with a lower rate of mortality over the first year after the consultation. …”
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    Universal electronic consultation program (e-consultation) of a cardiology department: long-term results in mortality
  7. 173667
    por Guo, Y, Lip, G Y H, Lip, G Y H
    Publicado 2022
    “…On multivariate analysis, AI ML model driven mAFA-based upstream risk factor control significantly reduced the changes in AF burden of both Δ 6 month (adjusted OR, 95% CI, 0.51,0.43–0.59) and Δ 12 month (0.39,0.32–0.47, all p<0.001). CONCLUSION: mHealth-AF care increased the adherence of using smart devices for AF detection. …”
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    mHealth based patient-centered self-management reduces the burden and episodes of atrial fibrillation
  8. 173668
    “…Among the participants, 54.8% reported acts of violence: 95.6% suffered verbal violence, 11.1% physical violence, and 19.9% other types. 39.5% of respondents experienced it at least once a week. …”
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    Aggression, mini-aggression, and abuse against health care workers during the COVID-19 pandemic
  9. 173669
    por Kong, X, Cao, R, Lu, T, Gao, S, Sun, G, Cao, F
    Publicado 2022
    “…After 12 months, compared with the control group, the intervention group saw the following metrics significantly reduced: systolic blood pressure (SBP) (131.66±9.43 vs 137.20±12.02 mmHg, P=0.000), total cholesterol (TC) (3.65±0.79 vs 4.08±0.82 mmol/L, P=0.001), low density lipoprotein cholesterol (LDL-C) (2.06±0.53 vs 2.38±0.61 mmol/L, P=0.002), and fasting blood glucose (FBG) (6.26±0.75 vs 6.81±0.97 mmol/L, P=0.000), while the following metrics went up significantly: blood pressure control rate (77.3% vs 59.1%, P=0.039), blood lipid control rate(39.4% vs 21.2%, P=0.037), glycemic control rate (71.2% vs 51.5%, P=0.031), and medication adherence score (7.10±0.77 vs 6.80±0.73, P=0.020). …”
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    Remote telemedicine strategy based on multi-risks intervention by intelligent wearable health devices in elderly comorbidities patients with coronary heart disease
  10. 173670
    “…Zio monitoring was associated with a significant reduction in the need for OPAs for fitting (0.5% vs. 96%, p<0.001) and follow-up (70.1% vs. 87.0, p<0.001), and resulted in a significant increase in ablations (5.9% vs. 1.0%, p=0.005) but not device implantations (5.9% vs. 3.9, p=0.209). CONCLUSION: Our findings indicate that Zio XT is associated with a statistically significant reduction in time to results, higher arrhythmia detection rate and a reduced need for OPAs. …”
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    A service evaluation of Zio XT: the Liverpool experience
  11. 173671
    “…RESULTS: Patients were mostly males (82%), HLA-B27 positive (84%), with a median age of 40 years (IQR: 32–48), disease duration of 5.5 years (IQR: 2–10), and a baseline Ankylosing Spondylitis Disease Activity Score (ASDAS) of 3.9 (IQR: 3.0–4.5). Compared to baseline, PRO-C1 levels were significantly increased after two weeks of treatment, C6M levels were significantly decreased after two and 22 weeks (repeated measures ANOVA, p=0.0014 and p=0.0015, respectively), EL-NE levels were significantly decreased after 2 weeks (p=0.0008), VICM levels were significantly decreased after two and 22 weeks (p=0.0163 and p=0.0374, respectively), and CRP were significantly decreased after two and 22 weeks (both p=0.0001). …”
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    Levels of extracellular matrix metabolites are associated with changes in Ankylosing Spondylitis Disease Activity Score and MRI inflammation scores in patients with axial spondyloarthritis during TNF inhibitor therapy
  12. 173672
    “…Adding three-yearly cervical screening among WLHIV (to girls' vaccination and 2 lifetime cervical screens) further reduced age-standardised cervical cancer incidence to 3.3 (1.8–3.6) per 100,000 women-years overall and to 5.2 (3.9–8.5) among WLHIV by 2120 and averted on average 12–13% additional cumulative cancer cases among all women and 21–24% among WLHIV than girls’ vaccination and 2 lifetime cervical screens over 25 years or longer. …”
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    Estimating the effect of HIV on cervical cancer elimination in South Africa: Comparative modelling of the impact of vaccination and screening
  13. 173673
    “…Rates were higher in males; the prevalence was 0·39% (0·37–0·41) in males and 0·29% (0·27–0·30) in females, and the respective incidences per 100 000 person‐years were 40·7 (38·2–43·2) and 28·3 (26·4–30·3). …”
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    Incidence and prevalence of psoriasis in multiethnic Johor Bahru, Malaysia: a population‐based cohort study using electronic health data routinely captured in the Teleprimary Care (TPC (®)) clinical information system from 2010 to 2020
  14. 173674
    “…For mild‐to‐moderate acne, the most effective options for each treatment type were as follows: topical pharmacological – combined retinoid with benzoyl peroxide (BPO) [mean difference 26·16%, 95% credible interval (CrI) 16·75–35·36%]; physical – chemical peels, e.g. salicylic or mandelic acid (39·70%, 95% CrI 12·54–66·78%) and photochemical therapy (combined blue/red light) (35·36%, 95% CrI 17·75–53·08%). …”
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    A systematic review and network meta‐analysis of topical pharmacological, oral pharmacological, physical and combined treatments for acne vulgaris
  15. 173675
    “…. = 1.19–2.04) and more than two (aOR = 2.32, 95% C.I. = 1.59–3.39) medical conditions were associated with low resilience level. …”
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    Resilience level and its association with maladaptive coping behaviours in the COVID-19 pandemic: a global survey of the general populations
  16. 173676
    “…RESULTS: Of the 105 patients, 50 were positive for M-CTCs (count ≥ 1 per 5 mL) and 39 showed high Ki67 expression (≥ 50% tumor cells were Ki67-positive). …”
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    Mesenchymal circulating tumor cells and Ki67: their mutual correlation and prognostic implications in hepatocellular carcinoma
  17. 173677
    por Katzdobler, Sabrina, Nitschmann, Alexander, Barthel, Henryk, Bischof, Gerard, Beyer, Leonie, Marek, Ken, Song, Mengmeng, Wagemann, Olivia, Palleis, Carla, Weidinger, Endy, Nack, Anne, Fietzek, Urban, Kurz, Carolin, Häckert, Jan, Stapf, Theresa, Ferschmann, Christian, Scheifele, Maximilian, Eckenweber, Florian, Biechele, Gloria, Franzmeier, Nicolai, Dewenter, Anna, Schönecker, Sonja, Saur, Dorothee, Schroeter, Matthias L., Rumpf, Jost-Julian, Rullmann, Michael, Schildan, Andreas, Patt, Marianne, Stephens, Andrew W., van Eimeren, Thilo, Neumaier, Bernd, Drzezga, Alexander, Danek, Adrian, Classen, Joseph, Bürger, Katharina, Janowitz, Daniel, Rauchmann, Boris-Stephan, Stöcklein, Sophia, Perneczky, Robert, Schöberl, Florian, Zwergal, Andreas, Höglinger, Günter U., Bartenstein, Peter, Villemagne, Victor, Seibyl, John, Sabri, Osama, Levin, Johannes, Brendel, Matthias
    Publicado 2022
    “…METHODS: Seventy-eight patients with 4RTs (71 ± 7 years, 39 female), 79 patients with other neurodegenerative diseases (67 ± 12 years, 35 female) and twelve age-matched controls (69 ± 8 years, 8 female) underwent dynamic (0–60 min) [(18)F]PI-2620 PET imaging. …”
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    Additive value of [(18)F]PI-2620 perfusion imaging in progressive supranuclear palsy and corticobasal syndrome
  18. 173678
    “…La détérioration clinique a été notée chez 154 patients (39,2 %) avec un transfert en milieu de réanimation pour 91 patients (23,2 %). …”
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    Pneumonie à SARS-COV-2 : rentabilité pronostique des scores de sévérité
  19. 173679
    “…La durée médiane de suivi sous double immunothérapie était de 7 mois. Au total, 36/91(39,5 %) patients ont présenté ou ont maintenu une réponse partielle avec le schéma double dose ; 8/91 (8,7 %) ont présenté ou ont maintenu une réponse complète ; 29/91 (31,8 %) ont arrêté le schéma double dose pour progression. …”
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    Sécurité et efficacité de l’immunothérapie selon un schéma double dose dans le CBNPC avancé : étude rétrospective multicentrique IDEE
  20. 173680
    “…RESULTS: Among 319 military personnel and veterans screened, 234 were randomized (mean [SD] age, 39.20 [7.72] years; 182 [78%] male participants), with 117 participants randomized to IOP-PE and 117 participants randomized to massed-PE. …”
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    Massed vs Intensive Outpatient Prolonged Exposure for Combat-Related Posttraumatic Stress Disorder: A Randomized Clinical Trial
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