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  1. 173681
    “…The median values of clinical factors were 66.08 ± 6.04 years for age, 36.62 ± 23.15 mL for TPV, 26.16 ± 33.59 ng/mL for tPSA and 0.15 ± 0.25 for f/t PSA ratio, 22.34 ± 3.14 kg/m(2) for BMI, 15 (5.1%) were pT1, 116 (39.1%) were pT2 and 166 (55.9%) were pT3. According to the student’s t test, patients in high GS group had a greater proportion of patients with pT3 (P<0.001), and higher NLR (P=0.04), SII (P=0.037) and tPSA (P=0.015) compared with low GS group, the distribution of age, TPV, f/t PSA ratio, BMI, LMR, NR, PLR, LR, MPV and RDW did not show any significantly statistical differences. …”
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    Role of inflammatory factors in prediction of Gleason score and its upgrading in localized prostate cancer patients after radical prostatectomy
  2. 173682
    “…Patient characteristics and management were similar for the groups of patients infected with different variants, except that those with the delta variant had a younger median age and less hypertension and diabetes. 90-day mortality was 42% (569 of 1345 patients died) overall, and 43% (297/686) in patients infected with wild-type SARS-CoV-2, 39% (152/391) in those with the alpha variant, 40% (78/195) in those with the delta variant, and 58% (42/73) in patients infected with other variants (mainly beta and gamma). …”
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    Comparative outcomes of extracorporeal membrane oxygenation for COVID-19 delivered in experienced European centres during successive SARS-CoV-2 variant outbreaks (ECMO-SURGES): an international, multicentre, retrospective cohort study
  3. 173683
    “…The mortality with unwashed and washed samples were 93.6 ± 0.2% and 83.2 ± 0.9% for PermaNet(®) Dual, 37.5 ± 2.9% and 14.4 ± 3.9% for PermaNet(®) 3.0, and 7.4 ± 5.1% and 11.7 ± 3.4% for PermaNet(®) 2.0, respectively. …”
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    Small-scale field evaluation of PermaNet(®) Dual (a long-lasting net coated with a mixture of chlorfenapyr and deltamethrin) against pyrethroid-resistant Anopheles gambiae mosquitoes from Tiassalé, Côte d’Ivoire
  4. 173684
    “…METHODS: A total of 200 participants with an average age of 39 (SD 8.44) years, primarily female (193/200, 97%), and White (160/200, 80%) were randomized to self-guided use of either PTSD Family Coach 1.0 (n=104) or a psychoeducation-only app (n=96) for 4 weeks. …”
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    The PTSD Family Coach App in Veteran Family Members: Pilot Randomized Controlled Trial
  5. 173685
    por Smith, Emily R, Oakley, Erin, Grandner, Gargi Wable, Ferguson, Kacey, Farooq, Fouzia, Afshar, Yalda, Ahlberg, Mia, Ahmadzia, Homa, Akelo, Victor, Aldrovandi, Grace, Tippett Barr, Beth A, Bevilacqua, Elisa, Brandt, Justin S, Broutet, Nathalie, Fernández Buhigas, Irene, Carrillo, Jorge, Clifton, Rebecca, Conry, Jeanne, Cosmi, Erich, Crispi, Fatima, Crovetto, Francesca, Delgado-López, Camille, Divakar, Hema, Driscoll, Amanda J, Favre, Guillaume, Flaherman, Valerie J, Gale, Chris, Gil, Maria M, Gottlieb, Sami L, Gratacós, Eduard, Hernandez, Olivia, Jones, Stephanie, Kalafat, Erkan, Khagayi, Sammy, Knight, Marian, Kotloff, Karen, Lanzone, Antonio, Le Doare, Kirsty, Lees, Christoph, Litman, Ethan, Lokken, Erica M, Laurita Longo, Valentina, Madhi, Shabir A, Magee, Laura A, Martinez-Portilla, Raigam Jafet, McClure, Elizabeth M, Metz, Tori D, Miller, Emily S, Money, Deborah, Moungmaithong, Sakita, Mullins, Edward, Nachega, Jean B, Nunes, Marta C, Onyango, Dickens, Panchaud, Alice, Poon, Liona C, Raiten, Daniel, Regan, Lesley, Rukundo, Gordon, Sahota, Daljit, Sakowicz, Allie, Sanin-Blair, Jose, Söderling, Jonas, Stephansson, Olof, Temmerman, Marleen, Thorson, Anna, Tolosa, Jorge E, Townson, Julia, Valencia-Prado, Miguel, Visentin, Silvia, von Dadelszen, Peter, Adams Waldorf, Kristina, Whitehead, Clare, Yassa, Murat, Tielsch, Jim M
    Publicado 2023
    “…Pregnant women with SARS-CoV-2 infection—as compared with uninfected pregnant women—were at significantly increased risk of maternal mortality (10 studies; n=1490; RR 7.68, 95% CI 1.70 to 34.61); admission to intensive care unit (8 studies; n=6660; RR 3.81, 95% CI 2.03 to 7.17); receiving mechanical ventilation (7 studies; n=4887; RR 15.23, 95% CI 4.32 to 53.71); receiving any critical care (7 studies; n=4735; RR 5.48, 95% CI 2.57 to 11.72); and being diagnosed with pneumonia (6 studies; n=4573; RR 23.46, 95% CI 3.03 to 181.39) and thromboembolic disease (8 studies; n=5146; RR 5.50, 95% CI 1.12 to 27.12). …”
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    Adverse maternal, fetal, and newborn outcomes among pregnant women with SARS-CoV-2 infection: an individual participant data meta-analysis
  6. 173686
    “…Statistically-significant age*metabolite Pearson correlations were observed for tCho (r(98)=0.33, p<0.001), tCr (r(98)=0.60, p<0.001), and mI (r(98)=0.32, p=0.001) in the CSO and for NAAG (r(98)=0.26, p=0.008), tCho(r(98)=0.33, p<0.001), tCr (r(98)=0.39, p<0.001), and Gln (r(98)=0.21, p=0.034) in the PCC. …”
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    Neurometabolic timecourse of healthy aging
  7. 173687
    “…Of these, 211 were randomised and 207 were included in the final analysis (n=67 in the combination group, n=71 in the infliximab withdrawal group, and n=69 in the immunosuppressant withdrawal group). 39 patients had a relapse (eight [12%] of 67 in the combination group, 25 [35%] of 71 in the infliximab withdrawal group, six [9%] of 69 in the immunosuppressant withdrawal group). 2-year relapse rates were 14% (95% CI 4–23) in the combination group, 36% (24–47) in the infliximab withdrawal group, and 10% (2–18) in the immunosuppressant withdrawal group (hazard ratio [HR] 3·45 [95% CI 1·56–7·69], p=0·003, for infliximab withdrawal vs combination, and 4·76 [1·92–11·11], p=0·0004, for infliximab withdrawal vs immunosuppressant withdrawal). …”
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    Withdrawal of infliximab or concomitant immunosuppressant therapy in patients with Crohn's disease on combination therapy (SPARE): a multicentre, open-label, randomised controlled trial
  8. 173688
    “…In Sillence types III and IV, the telescopic rod had lower revision rate (III 24.8%; IV 20.9%) compared to the plate (III 97.2%, p<0.001; IV 80.3%, p<0.001), the elastic nail (III 100.0%, p=0.019; IV 73.9%, p<0.001) and the non-elongating rod (III 65.0%, p<0.001; IV46.9%, p<0.001); the median implant survival period of the telescopic rod (III 48.00 (IQR 28.50) months; IV 43.00 (33.00) months) is longer than the plate (III 11.00 (9.00) months, p<0.001; IV 19.00 (20.00) months, p<0.001), the elastic nail (III 45.00 (37.75) months, p=1.000; IV 19.00 (35.00) months, p=0.028) and the non-elongating rod (III 39.00 (31.75) months, p=0.473; IV 38.50 (29.75) months, p=1.000).A similar trend was observed in Sillence type I (p = 0.063, p = 0.003; respectively). …”
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    Which is the best femoral implant in children with osteogenesis imperfecta? a retrospective cohort study of 783 procedures
  9. 173689
    “…There were significantly increased risks of second thyroid (SIR: 1.89, 95% CI 1.49–2.38), corpus uteri (SIR: 1.84, 95% CI 1.53–2.23), ovary (SIR: 1.53, 95% CI 1.35–1.73), kidney (SIR: 1.43, 95% CI 1.17–1.73), oesophagus (SIR: 1.39, 95% CI 1.26–1.55), skin (melanoma) (SIR: 1.34, 95% CI 1.18–1.52), blood (leukaemia) (SIR: 1.30, 95% CI 1.17–1.45), lung (SIR: 1.25, 95% CI 1.03–1.51), stomach (SIR: 1.23, 95% CI 1.12–1.36) and bladder (SIR: 1.15, 95% CI 1.05–1.26) primaries. …”
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    Risks of second non-breast primaries following breast cancer in women: a systematic review and meta-analysis
  10. 173690
    “…All targets with less than CR (n = 39) had more than 20 cc of underdosed tumor. D70 (p = 0.038) correlated with OR, with mean D70 of 95 Gy for responders and 60 Gy for non-responders (p = 0.042). …”
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    For Hepatocellular Carcinoma Treated with Yttrium-90 Microspheres, Dose Volumetrics on Post-Treatment Bremsstrahlung SPECT/CT Predict Clinical Outcomes
  11. 173691
    “…RESULTS: Among 138 patients (mean [SD] age, 60.0 [10.9] years; 87 men [63.0%]; all of Asian race and Korean ethnicity), 68 (mean [SD] age, 56.7 [10.4] years; 39 men [57.4%]) were randomized to receive LPG-DTR and 69 (mean [SD] age, 61.3 [11.3] years; 48 men [69.6%]) were randomized to receive LTG. …”
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    Effect of Laparoscopic Proximal Gastrectomy With Double-Tract Reconstruction vs Total Gastrectomy on Hemoglobin Level and Vitamin B(12) Supplementation in Upper-Third Early Gastric Cancer: A Randomized Clinical Trial
  12. 173692
    “…The mortality rate was significantly higher in the elderly group (39.1% versus 14.3%, p<0.001)). In the elderly, age (adjusted odds ratio (aOR) 1.13; 95% confidence interval (CI) 1.1—1.2; p<0.001), male sex (aOR 3.64; 95%CI 1.5–8.8; p=0.004), do-not-resuscitate (DNR) status (aOR 12.46; 95%CI 3.8–40.7; p<0.001), diastolic blood pressure (aOR 0.96; 95%CI 0.9–1.0; p=0.002), body temperature (aOR 1.74; 95%CI 1.0–2.9; p=0.036), and Glasgow Coma Scale (GCS) score (aOR 0.71; 95%CI 0.5–1.0; p=0.026) were independent baseline and physiologic factors associated with in-hospital mortality. …”
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    Clinical factors associated with adverse clinical outcomes in elderly versus non-elderly COVID-19 emergency patients: a multi-center observational study
  13. 173693
    “…Meta-analysis showed that Karnofsky score: WMD = 16, 95% CI (9.52, 22.47); quality-of-life score: WMD = 8.55, 95%CI (6.08, 11.03); lesion diameter: WMD = −0.45, 95% CI (−0.75, −0.15); weight: WMD = 4.49, 95% CI (1.18, 7.80); CD3(+): WMD = 8.46, 95% CI (5.71, 11.20); CD4(+): WMD = 8.45, 95% CI (6.32, 10.57)+; CD8(+): WMD = −3.76, 95% CI (−6.34, −1.18); CD4(+)/CD8(+): WMD = 0.32, 95% CI (0.10, 0.53); MDSC: WMD = −2.88, 95% CI (−4.59, −1.17); NK: WMD = 3.67, 95% CI (2.63, 4.71); Treg: WMD = −1.42, 95% CI (−2.33, −0.51); CEA: WMD = −4.01, 95% CI (−4.12, −3.90); NSE: WMD = −4.00, 95% CI (−4.14, −3.86); IL-2: WMD = 9.45, 95% CI (8.08, 10.82); IL-4: WMD = −9.61, 95% CI (−11.16, −8.06); IL-5: WMD = −11.95, 95% CI (−13.51, −10.39); IL-6: WMD = −7.65, 95% CI (−8.70, −6.60); IL-2/IL-5: WMD = 0.51, 95% CI (0.47, 0.55); IFN-γ: WMD = 15.19, 95% CI (3.16, 27.23); IFN-γ/IL-4: WMD = 0.91, 95% CI (0.85, 0.97); VEGF: WMD = −59.29, 95% CI (−72.99, −45.58); TGF-α: WMD = −10.09, 95% CI (−12.24, −7.94); TGF-β: WMD = −135.62, 95% CI (−147.00, −124.24); TGF-β1: WMD = −4.22, 95% CI (−5.04, −3.41); arginase: WMD = −1.81, 95% CI (−3.57, −0.05); IgG: WMD = 1.62, 95% CI (0.18, 3.06); IgM: WMD = −0.45, 95% CI (−0.59, −0.31). …”
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    The Efficacy and Hemorheological Indexes of Ginseng and Its Active Components for Patients with Non-Small Cell Lung Cancer: A Systematic Review and Meta-Analysis
  14. 173694
    “…During the humanitarian intervention phase, the CCT improved coverage of measles vaccination (MCV1) from 39.2% to 77.5% (aOR 11.7, 95% CI [5.2, 26.1]; p < 0.001) and completion of the pentavalent series from 44.2% to 77.5% (aOR 8.9, 95% CI [2.6, 29.8]; p = < 0.001). …”
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    Evaluation of conditional cash transfers and mHealth audio messaging in reduction of risk factors for childhood malnutrition in internally displaced persons camps in Somalia: A 2 × 2 factorial cluster-randomised controlled trial
  15. 173695
    “…The CO bias between AutoEF and VTI(LVOT) was 1.33 l min(−1) (95%LOA: -1.72 – 4.38 l min(−1)) and 1.39 l min(−1) (95%LOA -1.34 – 4.12 l min(−1)) between AutoEF and thermodilution, respectively. …”
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    Quantification of left ventricular ejection fraction and cardiac output using a novel semi-automated echocardiographic method: a prospective observational study in coronary artery bypass patients
  16. 173696
    “…La fréquence du trouble du sommeil (score ˃ 10) était de 39 %. Les composantes 2 et 3 liées à la durée du sommeil et au délai d’endormissement étaient les plus affectées avec les scores moyens les plus élevés (1,37 ± 1,09 et 2,63 ± 0,8, respectivement). …”
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    Impact de l’infection au SARS-CoV-2 sur le sommeil du personnel soignant affecté au circuit COVID : étude comparative
  17. 173697
    por Strippel, Christine, Herrera-Rivero, Marisol, Wendorff, Mareike, Tietz, Anja K, Degenhardt, Frauke, Witten, Anika, Schroeter, Christina, Nelke, Christopher, Golombeck, Kristin S, Madlener, Marie, Rüber, Theodor, Ernst, Leon, Racz, Attila, Baumgartner, Tobias, Widman, Guido, Doppler, Kathrin, Thaler, Franziska, Siebenbrodt, Kai, Dik, Andre, Kerin, Constanze, Räuber, Saskia, Gallus, Marco, Kovac, Stjepana, Grauer, Oliver M, Grimm, Alexander, Prüss, Harald, Wickel, Jonathan, Geis, Christian, Lewerenz, Jan, Goebels, Norbert, Ringelstein, Marius, Menge, Til, Tackenberg, Björn, Kellinghaus, Christoph, Bien, Christian G, Kraft, Andrea, Zettl, Uwe, Ismail, Fatme Seval, Ayzenberg, Ilya, Urbanek, Christian, Sühs, Kurt-Wolfram, Tauber, Simone C, Mues, Sigrid, Körtvélyessy, Peter, Markewitz, Robert, Paliantonis, Asterios, Elger, Christian E, Surges, Rainer, Sommer, Claudia, Kümpfel, Tania, Gross, Catharina C, Lerche, Holger, Wellmer, Jörg, Quesada, Carlos M, Then Bergh, Florian, Wandinger, Klaus-Peter, Becker, Albert J, Kunz, Wolfram S, Meyer zu Hörste, Gerd, Malter, Michael P, Rosenow, Felix, Wiendl, Heinz, Kuhlenbäumer, Gregor, Leypoldt, Frank, Lieb, Wolfgang, Franke, Andre, Meuth, Sven G, Stoll, Monika, Melzer, Nico
    Publicado 2022
    “…The strongest associations were found for the DQA1*03:01-DQB1*03:02-DRB1*04:01HLA haplotype (P = 4.39 × 10(−4), OR = 2.5, 95%CI = 1.499–4.157) and DRB1*04:01 allele (P = 8.3 × 10(−5), OR = 2.4, 95%CI = 1.548–3.682) identified in our cohort. …”
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    A genome-wide association study in autoimmune neurological syndromes with anti-GAD65 autoantibodies
  18. 173698
    “…The smaller mean increases were observed specifically in the deep white matter regions of the left anterior corona radiata (intensive treatment, 30.3 mm(3) [95% CI, 16.0-44.5 mm(3)]; standard treatment, 80.5 mm(3) [95% CI, 53.8-107.2 mm(3)]), left tapetum (intensive treatment, 11.8 mm(3) [95% CI, 4.4-19.2 mm(3)]; standard treatment, 27.2 mm(3) [95% CI, 19.4-35.0 mm(3)]), left superior fronto-occipital fasciculus (intensive treatment, 3.2 mm(3) [95% CI, 0.7-5.8 mm(3)]; standard treatment, 9.4 mm(3) [95% CI, 5.5-13.4 mm(3)]), left posterior corona radiata (intensive treatment, 26.0 mm(3) [95% CI, 12.9-39.1 mm(3)]; standard treatment, 52.3 mm(3) [95% CI, 34.8-69.8 mm(3)]), left splenium of the corpus callosum (intensive treatment, 45.4 mm(3) [95% CI, 25.1-65.7 mm(3)]; standard treatment, 83.0 mm(3) [95% CI, 58.7-107.2 mm(3)]), left posterior thalamic radiation (intensive treatment, 53.0 mm(3) [95% CI, 29.8-76.2 mm(3)]; standard treatment, 106.9 mm(3) [95% CI, 73.4-140.3 mm(3)]), and right posterior thalamic radiation (intensive treatment, 49.5 mm(3) [95% CI, 24.3-74.7 mm(3)]; standard treatment, 102.6 mm(3) [95% CI, 71.0-134.2 mm(3)]). …”
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    Association of Intensive vs Standard Blood Pressure Control With Regional Changes in Cerebral Small Vessel Disease Biomarkers: Post Hoc Secondary Analysis of the SPRINT MIND Randomized Clinical Trial
  19. 173699
    “…EXPOSURES: Frailty was defined using a 39-item frailty index ranging from 0 to 1.00 as robust (<0.15), prefrail (0.15-0.24), mildly frail (0.25-0.34), and moderately to severely frail (≥0.35). …”
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    Assessment of Frailty Index at 66 Years of Age and Association With Age-Related Diseases, Disability, and Death Over 10 Years in Korea
  20. 173700
    “…Compared with early mobility group 0, mobility groups 4–7 and 1–3 were not associated with differences in incident proximal lower-limb deep-vein thrombosis (adjusted hazard ratio [aHR] 1.19, 95% confidence interval [CI] 0.16, 8.90; p = 0.87 and 0.91, 95% CI 0.39, 2.12; p = 0.83, respectively). However, early mobility groups 4–7 and 1–3 had lower 90-day mortality (aHR 0.47, 95% CI 0.22, 1.01; p = 0.052, and 0.43, 95% CI 0.30, 0.62; p < 0.0001, respectively). …”
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    Association of early mobility with the incidence of deep-vein thrombosis and mortality among critically ill patients: a post hoc analysis of PREVENT trial
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