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  1. 173781
    “…Primary analysis of the evaluable population (n = 39) found that the optimal doses of aldesleukin to induce 10% and 20% increases in Tregs were 0.101 × 10(6) IU/m(2) (standard error [SE] = 0.078, 95% CI = −0.052, 0.254) and 0.497 × 10(6) IU/m(2) (SE = 0.092, 95% CI = 0.316, 0.678), respectively. …”
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    Regulatory T Cell Responses in Participants with Type 1 Diabetes after a Single Dose of Interleukin-2: A Non-Randomised, Open Label, Adaptive Dose-Finding Trial
  2. 173782
    “…In treatment group, the period for involution of uterus was significantly shorter (29.39±0.50 vs. 32.12±0.82 days, p<0.05), with early onset of first postpartum estrus (67.65±1.67 vs. 79.43±3.06 days, p<0.01), shorter service period (90.89±4.41 vs. 105.09±4.76 days, p<0.05) and higher conception rate (55.00 vs. 40.00%) than in control group. …”
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    Effect of peripartum nutritional management on plasma profile of steroid hormones, metabolites, and postpartum fertility in buffaloes
  3. 173783
    “…The median duration of follow‐up after completion of treatment was between 12 and 39 months. Relapse was uncommon, with two cases among 140 participants treated for six months, and no events among 129 participants treated for nine months. …”
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    Six‐month therapy for abdominal tuberculosis
  4. 173784
    “…NAHS: 65.5 (3.7), 80.1 (3.3), 83.8 (4.5), 83.8 (3.9). Pain VAS: 5.4 (0.5), 2.6 (0.5), 2.5 (0.6), 2.6 (0.6). …”
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    Multi-centered Comparison of Patient Reported Outcomes After Hip Arthroscopy versus Combined Hip Arthroscopy Alone and Peri-acetabular Osteotomy in Patients with Acetabular Dysplasia
  5. 173785
    “…The most common Grade 3/4 adverse events were febrile neutropenia (39%; n=97/252), anemia (24%; n=61/252), thromobocytopenia (13%; n=33/252), sepsis (11%; n=28/252), and pneumonia (11%; n=27/252). …”
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    Selective Inhibition of FLT3 by Gilteritinib in Relapsed/Refractory Acute Myeloid Leukemia: a Multicenter, First-in-human, Open-label, Phase 1/2 Study
  6. 173786
    por Mackenzie, Grant A, Hill, Philip C, Sahito, Shah M, Jeffries, David J, Hossain, Ilias, Bottomley, Christian, Uchendu, Uchendu, Ameh, David, Ndiaye, Malick, Osuorah, Chidebereh D, Adeyemi, Oyedeji, Pathirana, Jayani, Olatunji, Yekini, Abatan, Bade, Ahameefula, Ebirim, Muhammad, Bilquees S, Fombah, Augustin E, Saha, Debasish, Mackenzie, Roslyn, Plumb, Ian, Akano, Aliu, Ebruke, Bernard, Ideh, Readon C, Kuti, Bankole, Githua, Peter, Olutunde, Emmanuel, Ofordile, Ogochukwu, Green, Edward, Usuf, Effua, Badji, Henry, Ikumapayi, Usman N A, Manjang, Ahmad, Salaudeen, Rasheed, Nsekpong, E David, Jarju, Sheikh, Antonio, Martin, Sambou, Sana, Ceesay, Lamin, Lowe-Jallow, Yamundow, Sowe, Dawda, Jasseh, Momodou, Mulholland, Kim, Knoll, Maria, Levine, Orin S, Howie, Stephen R, Adegbola, Richard A, Greenwood, Brian M, Corrah, Tumani
    Publicado 2017
    “…In children aged 2–4 years, incidence fell from 5·2 to 4·1 cases per 1000 person-years (22% decline, 1–39). Incidence of all clinical pneumonia increased by 4% (–1 to 8), but hospitalised cases declined by 8% (3–13). …”
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    Impact of the introduction of pneumococcal conjugate vaccination on pneumonia in The Gambia: population-based surveillance and case-control studies
  7. 173787
    “…Corticosteroids probably reduce deaths from pericarditis (RR 0.39, 95% CI 0.19 to 0.80; 660 participants, 4 trials, moderate certainty evidence). …”
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    Interventions for treating tuberculous pericarditis
  8. 173788
    “…Of 10,703 adults ages 18 years and older with coresiding household members surveyed, data from 7,522 adults (mean age 39 years) in 2,574 households with complete covariate information were analyzed. …”
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    Chronic disease concordance within Indian households: A cross-sectional study
  9. 173789
    “…The [Formula: see text] of rectum in the case of IMRT was lower than that in BW‐DAT, M‐DAT, 2A‐DAT, and DAT by 7.3%, 10.3%, 33.0%, and 17.6% of the prescribed dose (78 Gy in 39 fractions) respectively. The [Formula: see text] , [Formula: see text] , and [Formula: see text] of the rectum volume in the cases of IMRT and DAT were comparable (with a maximum variation of 4.5%); they were similarly comparable in the cases of M‐DAT and BW‐DAT (with maximum variation of 1.5%). …”
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    Comparison of intensity‐modulated radiotherapy and forward‐planning dynamic arc therapy techniques for prostate cancer
  10. 173790
    “…RESULTS: Among Wi-Fi plus 5 mmol/L trolox, Wi-Fi-exposed and Wi-Fi plus 10 mmol/L trolox groups, reactive oxygen species levels (45 min: 3.80 ± 0.41 RLU·10(−6)·ml(−1) vs. 7.50 ± 0.35 RLU·10(−6)·ml(−1) vs. 6.70 ± 0.47 RLU·10(−6)·ml(−1), P < 0.001; 90 min: 5.40 ± 0.21 RLU·10(−6)·ml(−1) vs. 10.10 ± 0.31 RLU·10(−6)·ml(−1) vs. 7.00 ± 0.42 RLU·10(−6)·ml(−1), P < 0.001, respectively), percentages of tail DNA (45 min: 16.8 ± 2.0% vs. 31.9 ± 2.5% vs. 61.3 ± 1.6%, P < 0.001; 90 min: 19.7 ± 1.5% vs. 73.7 ± 1.3% vs. 73.1 ± 1.1%, P < 0.001, respectively), 8-hydroxy-2’-deoxyguanosine (45 min: 51.89 ± 1.46 pg/ml vs. 104.89 ± 2.19 pg/ml vs. 106.11 ± 1.81 pg/ml, P = 0.012; 90 min: 79.96 ± 1.73 pg/ml vs. 141.73 ± 2.90 pg/ml vs. 139.06 ± 2.79 pg/ml; P < 0.001), and percentages of immotility sperm (45 min: 27.7 ± 2.7% vs. 41.7 ± 2.2% vs. 41.7 ± 2.5%; 90 min: 29.9 ± 3.3% vs. 58.9 ± 4.0% vs. 63.1 ± 4.0%; all P < 0.001) were lowest, and glutathione peroxidase (45 min: 60.50 ± 1.54 U/ml vs. 37.09 ± 1.77 U/ml vs. 28.18 ± 1.06 U/ml; 90 min: 44.61 ± 1.23 U/ml vs. 16.86 ± 0.93 U/ml vs. 29.94 ± 1.56 U/ml; all P < 0.001), percentages of head DNA (45 min: 83.2 ± 2.0% vs. 68.2 ± 2.5% vs. 38.8 ± 1.6%; 90 min: 80.3 ± 1.5% vs. 26.3 ± 1.3% vs. 26.9 ± 1.1%; all P < 0.001), percentages of sperm vitality (45 min: 89.5 ± 1.6% vs. 70.7 ± 3.1% vs. 57.7 ± 2.4%; 90 min: 80.8 ± 2.2% vs. 40.4 ± 4.0% vs. 34.7 ± 3.9%; all P < 0.001), and progressive sperm (45 min: 69.3 ± 2.7% vs. 55.8 ± 2.2% vs. 55.4 ± 2.5%; 90 min: 67.2 ± 3.3% vs. 38.2 ± 4.0% vs. 33.9 ± 4.0%; all P < 0.001) were highest in Wi-Fi plus 5 mmol/L trolox group at 45 and 90 min, respectively. …”
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    Moderate Dose of Trolox Preventing the Deleterious Effects of Wi-Fi Radiation on Spermatozoa In vitro through Reduction of Oxidative Stress Damage
  11. 173791
    por Harausz, Elizabeth P., Garcia-Prats, Anthony J., Law, Stephanie, Schaaf, H. Simon, Kredo, Tamara, Seddon, James A., Menzies, Dick, Turkova, Anna, Achar, Jay, Amanullah, Farhana, Barry, Pennan, Becerra, Mercedes, Chan, Edward D., Chan, Pei Chun, Ioana Chiotan, Domnica, Crossa, Aldo, Drobac, Peter C., Fairlie, Lee, Falzon, Dennis, Flood, Jennifer, Gegia, Medea, Hicks, Robert M., Isaakidis, Petros, Kadri, SM, Kampmann, Beate, Madhi, Shabir A., Marais, Else, Mariandyshev, Andrei, Méndez-Echevarría, Ana, Moore, Brittany Kathryn, Nargiza, Parpieva, Ozere, Iveta, Padayatchi, Nesri, ur-Rehman, Saleem-, Rybak, Natasha, Santiago-Garcia, Begoña, Shah, N. Sarita, Sharma, Sangeeta, Shim, Tae Sun, Skrahina, Alena, Soriano-Arandes, Antoni, van den Boom, Martin, van der Werf, Marieke J., van der Werf, Tjip S., Williams, Bhanu, Yablokova, Elena, Yim, Jae-Joon, Furin, Jennifer, Hesseling, Anneke C.
    Publicado 2018
    “…Of 910 (93%) children with documented HIV status, 359 (39%) were infected with HIV. When compared to clinically diagnosed patients, children with confirmed MDR-TB were more likely to be older, to be infected with HIV, to be malnourished, and to have severe tuberculosis (TB) on chest radiograph (p < 0.001 for all characteristics). …”
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    Treatment and outcomes in children with multidrug-resistant tuberculosis: A systematic review and individual patient data meta-analysis
  12. 173792
    “…Female children whose mothers were randomized to IPTp-DP4w had an apparently 4-fold higher incidence of malaria compared to female children whose mothers were randomized to IPTp-SP8w (0.65 versus 0.20 episodes PPY, aIRR 4.39, 95% CI 1.87–10.3, p = 0.001), but no significant association was observed in male children (0.20 versus 0.28 episodes PPY, aIRR 0.66, 95% CI 0.25–1.75, p = 0.42). …”
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    Dihydroartemisinin-piperaquine for intermittent preventive treatment of malaria during pregnancy and risk of malaria in early childhood: A randomized controlled trial
  13. 173793
    “…Norris, PhD(37), William Perry, PhD(7,85,39), Neil Pliskin, PhD(40), David Shafer, MBA(41), Nina Silverberg, PhD(42), Tresa Roebuck-Spencer, PhD(43,44), Colin M. …”
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    Population Health Solutions for Assessing Cognitive Impairment in Geriatric Patients
  14. 173794
    “…METHODS AND FINDINGS: The prospective cohort study Programming of Enhanced Adiposity Risk in Childhood–Early Screening (PEACHES) (n = 1,671) enrolled obese and normal weight mothers from August 2010 to December 2015 with trimester-specific data on glucose metabolism including GDM status at the end of the second trimester and maternal glycated hemoglobin (HbA(1c)) at delivery as a marker for late-pregnancy dysglycemia (HbA(1c) ≥ 5.7% [39 mmol/mol]). We assessed offspring short- and long-term outcomes up to 4 years, and maternal glucose metabolism 3.5 years postpartum. …”
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    Late-pregnancy dysglycemia in obese pregnancies after negative testing for gestational diabetes and risk of future childhood overweight: An interim analysis from a longitudinal mother–child cohort study
  15. 173795
    “…During the trial, 318 (39%) of 807 patients in the control group were prescribed an antibiotic by day 5, compared with 290 (36%) of 803 patients in CRP group A and 275 (34%) of 800 in CRP group B. …”
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    Effect of point-of-care C-reactive protein testing on antibiotic prescription in febrile patients attending primary care in Thailand and Myanmar: an open-label, randomised, controlled trial
  16. 173796
    “…Laboratory tests were as follows: creatinine kinase (CK) 3200 U/L (normal: 39–308 U/L), CK-MB 65.7 mcg/L (normal: 0–7.6 mcg/L), troponin I 0.209 ng/mL (normal: 0–0.056 ng/mL). …”
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    Myocarditis in a patient treated with Nivolumab and PROSTVAC: a case report
  17. 173797
    “…Time spent eating was significantly lower in the CON group than both HI and LC (CON = 7.79 ± 0.37, LC = 8.91 ± 0.38, LCM = 8.49 ± 0.42, HI = 9.55 ± 0.39; p = 0.007). The time spent drinking was also affected by treatment, with more time spent drinking in CON than LC (p = 0.024). …”
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    Feeding Strategies Before and at Mixing: The Effect on Sow Aggression and Behavior
  18. 173798
    por Voerman, Ellis, Santos, Susana, Patro Golab, Bernadeta, Amiano, Pilar, Ballester, Ferran, Barros, Henrique, Bergström, Anna, Charles, Marie-Aline, Chatzi, Leda, Chevrier, Cécile, Chrousos, George P., Corpeleijn, Eva, Costet, Nathalie, Crozier, Sarah, Devereux, Graham, Eggesbø, Merete, Ekström, Sandra, Fantini, Maria Pia, Farchi, Sara, Forastiere, Francesco, Georgiu, Vagelis, Godfrey, Keith M., Gori, Davide, Grote, Veit, Hanke, Wojciech, Hertz-Picciotto, Irva, Heude, Barbara, Hryhorczuk, Daniel, Huang, Rae-Chi, Inskip, Hazel, Iszatt, Nina, Karvonen, Anne M., Kenny, Louise C., Koletzko, Berthold, Küpers, Leanne K., Lagström, Hanna, Lehmann, Irina, Magnus, Per, Majewska, Renata, Mäkelä, Johanna, Manios, Yannis, McAuliffe, Fionnuala M., McDonald, Sheila W., Mehegan, John, Mommers, Monique, Morgen, Camilla S., Mori, Trevor A., Moschonis, George, Murray, Deirdre, Chaoimh, Carol Ní, Nohr, Ellen A., Nybo Andersen, Anne-Marie, Oken, Emily, Oostvogels, Adriëtte J. J. M., Pac, Agnieszka, Papadopoulou, Eleni, Pekkanen, Juha, Pizzi, Costanza, Polanska, Kinga, Porta, Daniela, Richiardi, Lorenzo, Rifas-Shiman, Sheryl L., Ronfani, Luca, Santos, Ana C., Standl, Marie, Stoltenberg, Camilla, Thiering, Elisabeth, Thijs, Carel, Torrent, Maties, Tough, Suzanne C., Trnovec, Tomas, Turner, Steve, van Rossem, Lenie, von Berg, Andrea, Vrijheid, Martine, Vrijkotte, Tanja G. M., West, Jane, Wijga, Alet, Wright, John, Zvinchuk, Oleksandr, Sørensen, Thorkild I. A., Lawlor, Debbie A., Gaillard, Romy, Jaddoe, Vincent W. V.
    Publicado 2019
    “…We observed that higher maternal pre-pregnancy BMI and gestational weight gain both in clinical categories and across their full ranges were associated with higher risks of childhood overweight/obesity, with the strongest effects in late childhood (odds ratios [ORs] for overweight/obesity in early, mid, and late childhood, respectively: OR 1.66 [95% CI: 1.56, 1.78], OR 1.91 [95% CI: 1.85, 1.98], and OR 2.28 [95% CI: 2.08, 2.50] for maternal overweight; OR 2.43 [95% CI: 2.24, 2.64], OR 3.12 [95% CI: 2.98, 3.27], and OR 4.47 [95% CI: 3.99, 5.23] for maternal obesity; and OR 1.39 [95% CI: 1.30, 1.49], OR 1.55 [95% CI: 1.49, 1.60], and OR 1.72 [95% CI: 1.56, 1.91] for excessive gestational weight gain). …”
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    Maternal body mass index, gestational weight gain, and the risk of overweight and obesity across childhood: An individual participant data meta-analysis
  19. 173799
    Publicado 2019
    “…We analysed individual participant data from 22 trials (n=134 537) and detailed summary data from one trial (n=12 705) of statin therapy versus control, plus individual participant data from five trials of more intensive versus less intensive statin therapy (n=39 612). We subdivided participants into six age groups (55 years or younger, 56–60 years, 61–65 years, 66–70 years, 71–75 years, and older than 75 years). …”
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    Efficacy and safety of statin therapy in older people: a meta-analysis of individual participant data from 28 randomised controlled trials
  20. 173800
    “…The primary outcome was the change in time in hypoglycaemia (<3.9 mmol/l) between baseline and 6 months in the full analysis set. …”
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    Impact of flash glucose monitoring on hypoglycaemia in adults with type 1 diabetes managed with multiple daily injection therapy: a pre-specified subgroup analysis of the IMPACT randomised controlled trial
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