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  1. 173801
    “…Levinson (1976) labeled this 20- to 39-year-old age range as "provisional adult," while Havighurst (1956) used the terms "young adult" or "early adulthood." …”
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    Challenges and Role Changes in Caring for Adult Children With Cancer
  2. 173802
    “…In Ontario, the prevalence of IBD among seniors increased by 5.2% per year, which outpaced the 3.9% per year rise observed in nonseniors. 3. Approximately 15% of IBD patients are newly diagnosed after the age of 65 years. 4. …”
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    The Impact of Inflammatory Bowel Disease in Canada 2018: IBD in Seniors
  3. 173803
    por Gameiro, S, Sousa-Leite, M, Vermeulen, N
    Publicado 2019
    “…MAIN RESULTS AND THE ROLE OF CHANCE: The final sample consisted of 658 participants (not possible to calculate response rate), with the majority being embryologists, biologists or geneticists (n = 268, 40.7%), followed by clinicians (n = 260, 39.5%), scientists (n = 48, 7.3%), nurses or midwives (n = 30, 4.6%), psychologists, counsellors or social workers (n = 28, 4.3%) and others (e.g. medical student, lab manager, marketing, ethicist; n = 24, 3.6%). …”
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    Dissemination, implementation and impact of the ESHRE evidence-based guidelines
  4. 173804
    “…The likelihood for early continuation of PrEP use (i.e., return for at least one PrEP refill within 45 days post initiation) was strongly associated with reported male-partner HIV status (HIV-positive 67%, -negative 39%, unknown 31%; overall effect p = 0.001), and a higher proportion of women ≥24 years old continued PrEP at 1 month compared with young women <24 years old (47% versus 29%; p = 0.002). …”
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    Integrating preexposure prophylaxis delivery in routine family planning clinics: A feasibility programmatic evaluation in Kenya
  5. 173805
    por Huang, Tao, Wang, Tiange, Zheng, Yan, Ellervik, Christina, Li, Xiang, Gao, Meng, Fang, Zhe, Chai, Jin-Fang, Ahluwalia, Tarun veer S., Wang, Yujie, Voortman, Trudy, Noordam, Raymond, Frazier-Wood, Alexis, Scholz, Markus, Sonestedt, Emily, Akiyama, Masato, Dorajoo, Rajkumar, Zhou, Ang, Kilpeläinen, Tuomas O., Kleber, Marcus E., Crozier, Sarah R., Godfrey, Keith M., Lemaitre, Rozenn, Felix, Janine F., Shi, Yuan, Gupta, Preeti, Khor, Chiea-Chuen, Lehtimäki, Terho, Wang, Carol A., Tiesler, Carla M. T., Thiering, Elisabeth, Standl, Marie, Rzehak, Peter, Marouli, Eirini, He, Meian, Lecoeur, Cécile, Corella, Dolores, Lai, Chao-Qiang, Moreno, Luis A., Pitkänen, Niina, Boreham, Colin A., Zhang, Tao, Saw, Seang Mei, Ridker, Paul M., Graff, Mariaelisa, van Rooij, Frank J. A., Uitterlinden, Andre G., Hofman, Albert, van Heemst, Diana, Rosendaal, Frits R., de Mutsert, Renée, Burkhardt, Ralph, Schulz, Christina-Alexandra, Ericson, Ulrika, Kamatani, Yoichiro, Yuan, Jian-Min, Power, Chris, Hansen, Torben, Sørensen, Thorkild I. A., Tjønneland, Anne, Overvad, Kim, Delgado, Graciela, Cooper, Cyrus, Djousse, Luc, Rivadeneira, Fernando, Jameson, Karen, Zhao, Wanting, Liu, Jianjun, Lee, Nanette R., Raitakari, Olli, Kähönen, Mika, Viikari, Jorma, Grote, Veit, Langhendries, Jean-Paul, Koletzko, Berthold, Escribano, Joaquin, Verduci, Elvira, Dedoussis, George, Yu, Caizheng, Tham, Yih Chung, Lim, Blanche, Lim, Sing Hui, Froguel, Philippe, Balkau, Beverley, Fink, Nadia R., Vinding, Rebecca K., Sevelsted, Astrid, Bisgaard, Hans, Coltell, Oscar, Dallongeville, Jean, Gottrand, Frédéric, Pahkala, Katja, Niinikoski, Harri, Hyppönen, Elina, Pedersen, Oluf, März, Winfried, Inskip, Hazel, Jaddoe, Vincent W. V., Dennison, Elaine, Wong, Tien Yin, Sabanayagam, Charumathi, Tai, E-Shyong, Mohlke, Karen L., Mackey, David A., Gruszfeld, Dariusz, Deloukas, Panagiotis, Tucker, Katherine L., Fumeron, Frédéric, Bønnelykke, Klaus, Rossing, Peter, Estruch, Ramon, Ordovas, Jose M., Arnett, Donna K., Meirhaeghe, Aline, Amouyel, Philippe, Cheng, Ching-Yu, Sim, Xueling, Teo, Yik Ying, van Dam, Rob M., Koh, Woon-Puay, Orho-Melander, Marju, Loeffler, Markus, Kubo, Michiaki, Thiery, Joachim, Mook-Kanamori, Dennis O., Mozaffarian, Dariush, Psaty, Bruce M., Franco, Oscar H., Wu, Tangchun, North, Kari E., Davey Smith, George, Chavarro, Jorge E., Chasman, Daniel I., Qi, Lu
    Publicado 2019
    “…Study-level data showed that a 1-SD decrease in birth weight due to the genetic risk score was associated with higher risk of T2D among all participants (odds ratio [OR], 2.10; 95% CI, 1.69-2.61; P = 4.03 × 10(−5)), among European participants (OR, 1.96; 95% CI, 1.42-2.71; P = .04), and among East Asian participants (OR, 1.39; 95% CI, 1.18-1.62; P = .04). Similar results were observed from summary-level analyses. …”
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    Association of Birth Weight With Type 2 Diabetes and Glycemic Traits: A Mendelian Randomization Study
  6. 173806
    por Davies, Edward, Hajela, Vijay
    Publicado 2019
    “…Subsequent genetic analysis at the Royal Free hospital for fever syndromes has not found a pre-described genetic polymorphism. CASE DESCRIPTION: A 39-year-old woman presented to A&E with dyspnoea, night sweats, lethargy and right upper quadrant pain. …”
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    19. Fever, dyspnoea and a raised CRP: just another chest sepsis?
  7. 173807
    “…However, there was more pronounced inhibition in the SLCO1B1 variant genotypes compared to reference genotypes (IC50 [µM]: *1a 15.9 ± 1.9; *1b 18.6 ± 5.7; *5 3.9 ± 2.0; *15 4.4 ± 0.8; p≤0.01; Ki: *1a 15.0 ± 1.8; *1b 17.5 ± 5.4; *5 3.8 ± 2.9; *15 4.3 ± 0.8; p≤0.01). …”
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    3012 Functional consequences of pravastatin isomerization on OATP1B1-mediated transport
  8. 173808
    por Winthrop, Kevin L., Saag, Kenneth, Cascino, Matthew D., Pei, Jinglan, John, Ani, Jahreis, Angelika, Haselkorn, Tmirah, Furst, Daniel E., Abdulky, M., Abeles, M., Adelglass, H., Ahmed, A., Alloway, J., Alper, J., Anand, A., Anderson, J., Arora, M., Askari, A., Baca, S., Bacha, D., Bagheri, S., Ballou, S., Bennett, R., Bidula, L., Blumstein, H., Bognar, M., Bohan, A., Boniske, C., Borofsky, M., Box, E., Braun, A., Brennan, T., Brent, L., Cabalar, I., Carteron, N., Chaudhary, K., Chauhan, A., Cima, M., Cochinwala, A., Cohen, H., Colburn, K., Conaway, D., Danning, C., Dao, K., Dean, J., Diab, I., Diegel, R., Ditzian‐Kadanoff, R., Dowd, J., Dugowson, C., Eggebeen, A., El‐Kadi, H., Feinberg, H., Feinman, M., Feinstein, J., Fischer, A., Foad, B., Fondal, M., Fraser, S., Fraser, A., Freeman, P., Garber, M., Goldstein, A., Golombek, S., Greenstein, N., Greenwald, M., Hakim, C., Halla, J., Hallegua, D., Han, K., Harris, B., Hauptman, H., Hirsh, J., Hoffman, M., Huntwork, J., Husni, M., Hyer, F., Hymowitz, R., Jones, R., Kanagasegar, S., Kappes, J., Keating, R., Kelly, G., Kim, J., King, C., Klashman, D., Knee, C., Kolba, K., Krick, G., Krug, H., Kumar, U., Lakhanpal, S., Lang, T., Lauter, S., Lawrence Ford, T., Lee, W., Lee, Y., Leisen, J., Levine, J., Lidman, R., Lipstate, J., Malinak, J., Marcus, R., Martin, D., Mehta, C., Melton, G., Metyas, S., Miller, K., Moidel, R., Moore, C., Mossell, J., Munoz, G., Murphy, F., Nami, A., Nascimento, J., Neal, N., Neiman, R., Neuwelt, C., Nguyen, P., Niemer, M., Oelke, K., Oza, M., Pachaidee, S., Patel, S., Pegram, S., Penmetcha, M., Perkins, J., Perl, A., Peterson, L., Pittsley, R., Portnoff, K., Rahmani, D., Raja, N., Ratnoff, W., Rezaian, M., Rhea, C., Rice, D., Ridley, D., Rivadeneira, A., Rizzo, W., Roane, G., Rocca, P., Rosen, M., Saikali, W., Saitta, M., Sankoorikal, A., Saway, P., Schneider, P., Schwartzman, S., Scoville, C., Shergy, W., Shiel, W, Shurmur, R., Sikes, D., Singhal, A., Snyder, A., Songcharoen, S., Sosenko, M., Soto Raices, O., Stahl, N., Stark, K., Strachan, M., Stupi, A., Sullivan, N., Sylvester, R., Tabechian, D., Tagoe, C., Taylor, P., Thakker, S., Thakor, M., Thakur, N., Tidmore, W., Toth, M., Trostle, D., Udell, J., Van de Stouwe, M., Venuturupalli, R., Weiss, D., Weselman, K., Winn, D., Yung, C., Zable, E., Zamiri, B.
    Publicado 2019
    “…RESULTS: Overall, 989 patients (safety‐evaluable population) received ≥1 dose of rituximab, with a total follow‐up of 3,844 patient‐years (mean duration 3.9 years). In total, 341 significant infections occurred in 197 patients (19.9%). …”
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    Long‐Term Safety of Rituximab in Patients With Rheumatoid Arthritis: Results of a Five‐Year Observational Study
  9. 173809
    “…The following are several key principles shared by both programs: (1) The importance of creative, applicable, and inclusive mission statements: (a) REACH seeks to facilitate communication, collaborative research, and service efforts between UTMB and Institute for Translational Sciences investigators and Galveston County community leaders; (b) The SCI Café hosts interactive dialogs that serve as a medium for priming, organizing, communicating and strategizing among the individuals involved in team science via community-based research projects. (2) Increasing scientific and health literacy: (a) REACH seeks to increase literacy through both short-term and long-term interactions; (b) The SCI Café focuses on short-term yet intensive interaction through conversations among researchers, clinicians, and the public. (3) Sharing timely scientific public health information with the community: (a) REACH seeks information from community leaders on relevant topics; (b) The SCI Café can mobilize quickly to respond to timely topics by direct communication with a wide range of stakeholders, academic as well as community based. (4) Sharing leadership with the community: (a) REACH establishes formal relationships with 23 UTMB units and 39 broad-based, high impact Galveston County organizations. …”
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    2316 The extra-territorial translational team: Advances in multi-faceted community engagement
  10. 173810
    “…Low-density lipoprotein–cholesterol differences in OPCOS versus controls were lower among females (β(f) = −0.39(95%CI: −0.62 to 0.16)), but comparable between male OPCOS and male controls (β(m) = 0.27(95%CI: −0.03 to 0.57)), with interaction-test: P < 0.01. …”
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    Cardiometabolic health in offspring of women with PCOS compared to healthy controls: a systematic review and individual participant data meta-analysis
  11. 173811
    “…Having comorbid physical illness has significant negative association with physical domain (beta = − 2.74, p < 0.001), psychological (beta = − 2.13, p < 0.004), social relationships (beta = − 1.25, p < 0.007), environmental domain (beta = − 3.39, p < 0.001) and overall quality of life (beta = − 9.9, p < 0.001). …”
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    Quality of life and its association with current substance use, medication non-adherence and clinical factors of people with schizophrenia in Southwest Ethiopia: a hospital-based cross-sectional study
  12. 173812
    “…RESULTS: Of 5125 hospitalized older adults, 15% were non-frail, 39% pre-frail, 40% frail, and 6% most frail. 11% died, and poor recovery was experienced by 520/4544=11% of survivors. …”
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    Frailty Hinders Recovery From Acute Respiratory Illness in Older Adults
  13. 173813
    por Captur, Gabriella, Bhandari, Abhiyan, Brühl, Rüdiger, Ittermann, Bernd, Keenan, Kathryn E., Yang, Ye, Eames, Richard J., Benedetti, Giulia, Torlasco, Camilla, Ricketts, Lewis, Boubertakh, Redha, Fatih, Nasri, Greenwood, John P., Paulis, Leonie E. M., Lawton, Chris B., Bucciarelli-Ducci, Chiara, Lamb, Hildo J., Steeds, Richard, Leung, Steve W., Berry, Colin, Valentin, Sinitsyn, Flett, Andrew, de Lange, Charlotte, DeCobelli, Francesco, Viallon, Magalie, Croisille, Pierre, Higgins, David M., Greiser, Andreas, Pang, Wenjie, Hamilton-Craig, Christian, Strugnell, Wendy E., Dresselaers, Tom, Barison, Andrea, Dawson, Dana, Taylor, Andrew J., Mongeon, François-Pierre, Plein, Sven, Messroghli, Daniel, Al-Mallah, Mouaz, Grieve, Stuart M., Lombardi, Massimo, Jang, Jihye, Salerno, Michael, Chaturvedi, Nish, Kellman, Peter, Bluemke, David A., Nezafat, Reza, Gatehouse, Peter, Moon, James C.
    Publicado 2020
    “…RESULTS: Over 2 years, phantom gel integrity remained intact (no rips/tears), B(0) and B(1) homogenous, and “reference” T(1) stable compared to baseline (% change at 1.5 T, 1.95 ± 1.39%; 3 T, 2.22 ± 1.44%). Per degrees Celsius, 1.5 T, T(1) (MOLLI 5s(3s)3s) increased by 11.4 ms in long native blood tubes and decreased by 1.2 ms in short post-contrast myocardium tubes. …”
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    T(1) mapping performance and measurement repeatability: results from the multi-national T(1) mapping standardization phantom program (T1MES)
  14. 173814
    “…For patients, mean number of beads was 3.9 (SD 4) at baseline and 3.2 (SD 3.4) at FU, while controls decided after 6.3 (SD 4.6) beads on average at baseline and 6.5 (SD 3.2) at FU. …”
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    T52. COGNITION, METACOGNITION AND SOCIAL COGNITION AFTER A FIRST EPISODE PSYCHOSIS. PRELIMINARY RESULTS FROM A 5-YEAR-FOLLOW-UP STUDY
  15. 173815
    “…Furthermore, we found significant group-by-region interaction (F2, 68=7.97, p=0.0008), group (F1, 34=8.1, p=0.007) and ROI (F2, 68=510.9, p<0.0001) effects on DVR, with significant reductions of large effect size in the FC (SCZ=2.93 [0.17]; HV=3.48 [0.09]; t=2.89, df=34.0, p=0.01, Cohen’s d=1.0), ACC (SCZ=3.39 [0.17]; HV=3.99 [0.09]; t=3.05, df=34.0, p=0.01, Cohen’s d=1.0) and, additionally, hippocampus (SCZ=2.40 [0.12]; HV=2.74 [0.07]; t=2.32, df=34.0, p=0.03, Cohen’s d=0.8). …”
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    O11.3. SYNAPTIC MARKER PROTEIN SV2A IS REDUCED IN SCHIZOPHRENIA IN VIVO AND UNAFFECTED BY ANTIPSYCHOTICS IN RATS
  16. 173816
    “…Among all follow-up respondents, a weighted 37.5% (95% CI, 35.3%-39.9%) were aged 19 to 34 years, 34.0% (95% CI, 31.8%-36.2%) were aged 35 to 50 years, and 28.5% (95% CI, 26.7%-30.3%) were aged 51 to 64 years; 53.0% (95% CI, 50.8%-55.3%) were female. …”
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    Examination of Changes in Health Status Among Michigan Medicaid Expansion Enrollees From 2016 to 2017
  17. 173817
    “…Late changes in lateral flow serological assay bands were recorded in 74 (9·3%) of 800 cassettes (35 [8·8%] of 400 Encode assays; 39 [9·8%] of 400 Onsite assays), but only seven (all Onsite assays) of these changes were concordant with the laboratory immunoassay. …”
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    Point-of-care serological assays for delayed SARS-CoV-2 case identification among health-care workers in the UK: a prospective multicentre cohort study
  18. 173818
    “…Of the remaining 6834 participants in the intervention group, 2679 (39%) expressed an interest in undergoing the Cytosponge-TFF3 procedure. …”
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    Cytosponge-trefoil factor 3 versus usual care to identify Barrett's oesophagus in a primary care setting: a multicentre, pragmatic, randomised controlled trial
  19. 173819
    por Philips, Elise M., Santos, Susana, Trasande, Leonardo, Aurrekoetxea, Juan J., Barros, Henrique, von Berg, Andrea, Bergström, Anna, Bird, Philippa K., Brescianini, Sonia, Ní Chaoimh, Carol, Charles, Marie-Aline, Chatzi, Leda, Chevrier, Cécile, Chrousos, George P., Costet, Nathalie, Criswell, Rachel, Crozier, Sarah, Eggesbø, Merete, Fantini, Maria Pia, Farchi, Sara, Forastiere, Francesco, van Gelder, Marleen M. H. J., Georgiu, Vagelis, Godfrey, Keith M., Gori, Davide, Hanke, Wojciech, Heude, Barbara, Hryhorczuk, Daniel, Iñiguez, Carmen, Inskip, Hazel, Karvonen, Anne M., Kenny, Louise C., Kull, Inger, Lawlor, Debbie A., Lehmann, Irina, Magnus, Per, Manios, Yannis, Melén, Erik, Mommers, Monique, Morgen, Camilla S., Moschonis, George, Murray, Deirdre, Nohr, Ellen A., Nybo Andersen, Anne-Marie, Oken, Emily, Oostvogels, Adriëtte J. J. M., Papadopoulou, Eleni, Pekkanen, Juha, Pizzi, Costanza, Polanska, Kinga, Porta, Daniela, Richiardi, Lorenzo, Rifas-Shiman, Sheryl L., Roeleveld, Nel, Rusconi, Franca, Santos, Ana C., Sørensen, Thorkild I. A., Standl, Marie, Stoltenberg, Camilla, Sunyer, Jordi, Thiering, Elisabeth, Thijs, Carel, Torrent, Maties, Vrijkotte, Tanja G. M., Wright, John, Zvinchuk, Oleksandr, Gaillard, Romy, Jaddoe, Vincent W. V.
    Publicado 2020
    “…However, the corresponding risk estimates were smaller than for women who continued the same amount of cigarettes throughout pregnancy (OR 1.89 [95% CI 1.52–2.34] instead of OR 2.20 [95% CI 2.02–2.42] when reducing from 5–9 to ≤4 cigarettes/day; OR 2.79 [95% CI 2.39–3.25] and OR 1.93 [95% CI 1.46–2.57] instead of OR 2.95 [95% CI 2.75–3.15] when reducing from ≥10 to 5–9 and ≤4 cigarettes/day, respectively [P values < 0.001]). …”
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    Changes in parental smoking during pregnancy and risks of adverse birth outcomes and childhood overweight in Europe and North America: An individual participant data meta-analysis of 229,000 singleton births
  20. 173820
    “…With the reduction of muscle tone, strength of those target muscles in our cases improved dramatically with statistical significance achieved (3.9 ± 1.0 at the time of last follow-up vs. 3.3 ± 0.8 pre-op), and as well as ROM. …”
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    Whether the newly modified rhizotomy protocol is applicable to guide single-level approach SDR to treat spastic quadriplegia and diplegia in pediatric patients with cerebral palsy?
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